Mechanism of the antiproliferative activity of some naphthalene diimide G-quadruplex ligands

Molecular Pharmacology

Volumn 83, Issue 2, 2013, Pages 470-480

  Hampel, Sonja M ^a   Pepe, Antonella ^b   Greulich Bode, Karin M ^c   Malhotra, Sanjay V ^b   Reszka, Anthony P ^a   Veith, Sebastian ^d   Boukamp, Petra ^c   Neidle, Stephen ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b SAIC FREDERICK INC   (United States)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GUANINE QUADRUPLEX; N,N' BIS[3 (4 METHYLPIPERAZIN 1 YL)PENTYLAMINO] 2,6 BIS[3 (4 METHYLPIPERAZIN 1 YL)PENTYLAMINO] 1,2,5,8 NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE; N,N' BIS[3 (DIMETHYLAMINE)PROPYLAMINO] 2,6 BIS[3 (DIMETHYLAMINE)PROPYLAMINO] 1,2,5,8 NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE; N,N' BIS[3 (PYRROLIDINE)PROPYLAMINO] 2,6 BIS[3 (PYRROLIDINE)PROPYLAMINO] 1,2,5,8 NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE; NAPHTHALENE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHROMOSOME INSERTION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA DAMAGE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; MITOSIS; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; SENESCENCE; STRUCTURE ACTIVITY RELATION; TELOMERE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA; DNA DAMAGE; G-QUADRUPLEXES; HUMANS; IMIDES; LIGANDS; MCF-7 CELLS; MITOSIS; NAPHTHALENES; ONCOGENES; TELOMERE;

EID: 84872738911     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.081075     Document Type: Article

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