The matrix metalloproteinase inhibitor marimastat promotes neural progenitor cell differentiation into neurons by gelatinase-independent TIMP-2-dependent mechanisms

Stem Cells and Development

Volumn 22, Issue 3, 2013, Pages 345-358

  Sinno, Maddalena ^a   Biagioni, Stefano ^a   Ajmone Cat, Maria Antonietta ^b   Pafumi, Irene ^a   Caramanica, Pasquale ^a   Medda, Virginia ^c   Tonti, Gaetana ^c   Minghetti, Luisa ^b   Mannello, Ferdinando ^c   Cacci, Emanuele ^a,d  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c UNIVERSITY OF URBINO   (Italy)

^d Pasteur Institute   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE; GELATINASE A; GELATINASE B; MARIMASTAT; SMALL INTERFERING RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HES 5;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN NERVE CELL; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SYNTHESIS; GENE EXPRESSION; MOUSE; NERVE CELL CULTURE; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBVENTRICULAR ZONE; ZYMOGRAPHY;

ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HYDROXAMIC ACIDS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASE INHIBITORS; MICE; NEURAL STEM CELLS; NEURONS; RNA, SMALL INTERFERING; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

MURINAE;

EID: 84872718436     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2012.0299     Document Type: Article

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