TGF-β as a therapeutic target in high grade gliomas-Promises and challenges

Biochemical Pharmacology

Volumn 85, Issue 4, 2013, Pages 478-485

  Joseph, Justin V ^a   Balasubramaniyan, Veerakumar ^a   Walenkamp, Annemiek ^a   Kruyt, Frank A E ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Cancer stem cells; Glioma; Microenvironment; TGF ; Therapy

Indexed keywords

2 (5 CHLORO 2 FLUOROPHENYL) 4 (4 PYRIDINYLAMINO)PTERIDINE; 4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; FRESOLIMUMAB; LOMUSTINE; LY 2109761; LY 2157299; LY 364947; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY ID 11; NEUTRALIZING ANTIBODY; PEPTIDE VACCINE; PHOSPHOTRANSFERASE INHIBITOR; TEMOZOLOMIDE; TRABEDERSEN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1 INHIBITOR; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; BRAIN; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STEM CELL; CELL INVASION; CELL PROLIFERATION; DRUG DOSE ESCALATION; DRUG TARGETING; GLIOBLASTOMA; GLIOMA; HUMAN; HYPOXIA; IMMUNE RESPONSE; NONHUMAN; OUTCOME ASSESSMENT; PHENOTYPE; PRIORITY JOURNAL; RADIOSENSITIVITY; REVIEW; THERAPY RESISTANCE; TUMOR GROWTH; TUMOR IMMUNITY;

EID: 84872684798     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.11.005     Document Type: Note

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