Virtual ligand-based screening reveals purmorphamine analogs with the capacity to induce the osteogenic differentiation of human mesenchymal stem cells

Cells Tissues Organs

Volumn 197, Issue 2, 2013, Pages 89-102

  Granéli, Cecilia ^a,b   Karlsson, Camilla ^a,b   Lindahl, Anders ^a,b   Thomsen, Peter ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b BIOMATCELL   (Sweden)

Author keywords

Mesenchymal stem cells; Osteoblast differentiation; Purmorphamine; Virtual ligand based screening

Indexed keywords

ALKALINE PHOSPHATASE; AMINE; BIOLOGICAL MARKER; CALCIUM; PROTEIN CCND1; PURMORPHAMINE DERIVATIVE; PURVALANOL; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ARTICLE; BONE DEVELOPMENT; BONE MARROW; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL RENEWAL; CONNECTIVE TISSUE; CONTROLLED STUDY; DRUG SCREENING; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE ENGINEERING; VIRTUAL LIGAND BASED SCREENING;

EID: 84872681406     PISSN: 14226405     EISSN: 14226421     Source Type: Journal    
DOI: 10.1159/000342796     Document Type: Article

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