L-Valine production with minimization of by-products' synthesis in Corynebacterium glutamicum and Brevibacterium flavum

Amino Acids

Volumn 43, Issue 6, 2012, Pages 2301-2311

  Hou, Xiaohu ^a,b,c   Chen, Xinde ^a,b   Zhang, Yue ^c   Qian, He ^c   Zhang, Weiguo ^c  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b GUANGZHOU INSTITUTE OF ENERGY CONVERSION   (China)

^c JIANGNAN UNIVERSITY   (China)

Author keywords

AlaT; AvtA; Brevibacterium flavum; Corynebacterium glutamicum; L Valine

Indexed keywords

ALANINE; GLUTAMIC ACID; ISOLEUCINE; LACTIC ACID; VALINE;

ALAT GENE; AMINO ACID SYNTHESIS; ARTICLE; AVTA GENE; BACTERIAL GENE; BACTERIAL STRAIN; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; DOWN REGULATION; FED BATCH FERMENTATION; GENE INACTIVATION; ILVEBN C GENE; NONHUMAN; OXYGEN SATURATION; OXYGEN SUPPLY; PRECURSOR; PRIORITY JOURNAL; PROMOTER REGION;

BREVIBACTERIUM FLAVUM; CORYNEBACTERIUM GLUTAMICUM; FERMENTATION; OXYGEN; VALINE;

BREVIBACTERIUM FLAVUM; CORYNEBACTERIUM GLUTAMICUM;

EID: 84872677487     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-012-1308-9     Document Type: Article

References (30)

1. Almaas E, Kovacs B, Vicsek T, Oltvai ZN, Barabasi AL (2004) Global organization of metabolic fluxes in the bacterium Escherichia coli. Nature 427(6977):839-843. doi:10.1038/nature02289 (Pubitemid 38297745)
2. Ausubel FM, Brent R, Klingston RE, Moore DD, Deidman JD, Smith JA, Struhl K (2005) Recombineering: genetic engineering in bacteria using homologous recombination. In: Thomason L, Court DL, Bubunenko M, Constantino N, Wilson H, Datta S, Oppenheim A (eds) Current protocols in molecular biology. John Wiley & Sons, New York, p 1.16.11-1.16.21
3. Becker J, Zelder O, Hafner S, Schroder H, Wittmann C (2011) From zero to hero-design-based systems metabolic engineering of Corynebacterium glutamicum for L-lysine production. Metab Eng 13(2):159-168. doi:10.1016/j.ymben.2011.01. 003
4. Blombach B, Schreiner ME, Holatko J, Bartek T, Oldiges M, Eikmanns BJ (2007) L-Valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum. Appl Environ Microbiol 73(7):2079-2084. doi:10.1128/AEM. 02826-06 (Pubitemid 46649496)
5. Blombach B, Schreiner ME, Bartek T, Oldiges M, Eikmanns BJ (2008) Corynebacterium glutamicum tailored for high-yield L-valine production. Appl Microbiol Biotechnol 79(3):471-479. doi:10.1007/s00253-008-1444-z (Pubitemid 351704103)
6. Datsenko KA, Wanner BL (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A 97(12):6640-6645. doi:10.1073/pnas. 120163297 (Pubitemid 30412767)
7. Eggeling L (2001) Amino acids. In: Ratledge C, Kristiansen B (eds) Basic biotechnology. Cambridge University Press, London, pp 281-303
8. Eggeling L, Bott M (2005) Handbook of Corynebacterium glutamicum. CRC, Boca Raton
9. Elisakova V, Patek M, Holatko J, Nesvera J, Leyval D, Goergen JL, Delaunay S (2005) Feedback-resistant acetohydroxy acid synthase increases valine production in Corynebacterium glutamicum. Appl Environ Microbiol 71(1):207-213. doi:10.1128/AEM.71.1.207-213.2005 (Pubitemid 40116269)
10. Hammer K, Mijakovic I, Jensen PR (2006) Synthetic promoter libraries-tuning of gene expression. Trends Biotechnol 24(2):53-55. doi:10.1016/j.tibtech.2005.12.003 (Pubitemid 43151974)
11. Hermann T (2003) Industrial production of amino acids by coryneform bacteria. J Biotechnol 104(1-3):155-172. doi:10.1016/S0168-1656(03)00149-4 (Pubitemid 37011355)
12. Holatko J, Elisakova V, Prouza M, Sobotka M, Nesvera J, Patek M (2009) Metabolic engineering of the L-valine biosynthesis pathway in Corynebacterium glutamicum using promoter activity modulation. J Biotechnol 139(3):203-210. doi:10.1016/j. jbiotec.2008.12.005
13. Hou X, Ge X, Wu D, Qian H, Zhang W (2012) Improvement of L-valine production at high temperature in Brevibacterium flavum by overexpressing ilvEBNrC genes. J Ind Microbiol Biotechnol 39(1):63-72. doi:10.1007/s10295-011- 1000-1
14. Ikeda M (2003) Amino acid production processes. Adv Biochem Eng Biotechnol 79:1-35
15. Lee KH, Park JH, Kim TY, Kim HU, Lee SY (2007) Systems metabolic engineering of Escherichia coli for L-threonine production. Mol Syst Biol 3:149. doi:10.1038/msb4100196 (Pubitemid 350223361)
16. Leuchtenberger W, Huthmacher K, Drauz K (2005) Biotechnological production of amino acids and derivatives: current status and prospects. Appl Microbiol Biotechnol 69(1):1-8. doi:10.1007/s00253-005-0155-y (Pubitemid 41719169)
17. Lindroth P, Mopper K (1979) High performance liquid chromatographic determination of subpicomole amounts of amino acids by precolumn fluorescence derivatization with o-phthalaldehyde. Anal Chem 51:1667-1674
18. Marienhagen J, Eggeling L (2008) Metabolic function of Corynebacterium glutamicum aminotransferases AlaT and AvtA and impact on L-valine production. Appl Environ Microbiol 74(24):7457-7462. doi:10.1128/AEM.01025-08
19. Marienhagen J, Kennerknecht N, Sahm H, Eggeling L (2005) Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum. J Bacteriol 187(22):7639-7646. doi:10.1128/Jb.187. 22.7639-7646.2005 (Pubitemid 41587702)
20. Park JH, Lee SY (2010) Fermentative production of branched chain amino acids: A focus on metabolic engineering. Appl Microbiol Biotechnol 85(3):491-506. doi:10.1007/s00253-009-2307-y
21. Park JH, Lee KH, Kim TY, Lee SY (2007) Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation. Proc Natl Acad Sci U S A 104(19):7797-7802. doi:10.1073/pnas.0702609104 (Pubitemid 47185831)
22. Patek M (2007) Branched-chain amino acid. In: VF Wendisch (ed) Amino acid biosynthesis. Springer, Berlin Heidelberg, p 130-162
23. Radmacher E, Vaitsikova A, Burger U, Krumbach K, Sahm H, Eggeling L (2002) Linking central metabolism with increased pathway flux: L-valine accumulation by Corynebacterium glutamicum. Appl Environ Microbiol 68(5):2246-2250. doi: 10.1128/AEM.68.5.2246-2250.2002 (Pubitemid 34477818)
24. Sahm H, Eggeling L (1999) D-Pantothenate synthesis in Corynebacterium glutamicum and use of panBC and genes encoding L-valine synthesis for D-pantothenate overproduction. Appl Environ Microbiol 65(5):1973-1979
25. Sambrook J, Russel DV (2001) Molecular cloning, a laboratory manual. Cold Spring Harbor Laboratory Press, New York
26. Schafer A, Tauch A, Jager W, Kalinowski J, Thierbach G, Puhler A (1994) Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicum. Gene 145(1):69-73 (Pubitemid 24224965)
27. Solem C, Koebmann B, Yang F, Jensen PR (2007) The las enzymes control pyruvate metabolism in Lactococcus lactis during growth on maltose. J Bacteriol 189(18):6727-6730. doi:10.1128/JB. 00902-07 (Pubitemid 47397380)
28. Xu DQ, Tan YZ, Huan XJ, Hu XQ, Wang XY (2010) Construction of a novel shuttle vector for use in Brevibacterium flavum, an industrial amino acid producer. J Microbiol Meth 80(1):86-92. doi:10.1016/j.mimet.2009.11.003
29. Yamada K, Kinoshita S, Tsunoda T, Aida K (1972) The microbial production of amino acids. Halsted Press, New York
30. Zimmermann HF, Anderlei T, Buchs J, Binder M (2006) Oxygen limitation is a pitfall during screening for industrial strains. Appl Microbiol Biotechnol 72(6):1157-1160. doi:10.1007/s00253-006-0414-6 (Pubitemid 44564449)