The las enzymes control pyruvate metabolism in Lactococcus lactis during growth on maltose

Journal of Bacteriology

Volumn 189, Issue 18, 2007, Pages 6727-6730

  Solem, Christian ^a   Koebmann, Brian ^a   Yang, Fen ^a   Jensen, Peter R ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTOKINASE; BACTERIAL ENZYME; CARBOXYLIC ACID; LACTATE DEHYDROGENASE; MALTOSE; PYRUVIC ACID;

ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; CARBOHYDRATE METABOLISM; ENZYME ACTIVITY; FERMENTATION; LACTOCOCCUS LACTIS; NONHUMAN; OPERON; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

BACTERIAL PROTEINS; CULTURE MEDIA; FERMENTATION; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCOLYSIS; INDUSTRIAL MICROBIOLOGY; L-LACTATE DEHYDROGENASE; LACTOCOCCUS LACTIS; MALTOSE; OPERON; PHOSPHOFRUCTOKINASES; PYRUVATE KINASE; PYRUVIC ACID;

LACTOCOCCUS LACTIS;

EID: 34548550474     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.00902-07     Document Type: Article

References (19)

1. Andersen, H. W., M. B. Pedersen, K. Hammer, and P. R. Jensen. 2001. Lactate dehydrogenase has no control on lactate production but has a strong negative control on formate production in Lactococcus lactis. Eur. J. Biochem. 268:6379-6389.
2. Andersen, H. W., C. Solem, K. Hammer, and P. R. Jensen. 2001. Twofold reduction of phosphofructokinase activity in Lactococcus lactis results in strong decreases in growth rate and in glycolytic flux. J. Bacteriol. 183:3458-3467.
3. Brøndsted, L., and K. Hammer. 1999. Use of the integration elements encoded by the temperate lactococcal bacteriophage TP901-1 to obtain chromosomal single-copy transcriptional fusions in Lactococcus lactis. Appl. Environ. Microbiol. 65:752-758.
4. Crow, V. L., and G. G. Pritchard. 1977. Fructose 1,6-diphosphate-activated L-lactate dehydrogenase from Streptococcus lactis: kinetic properties and factors affecting activation. J. Bacteriol. 131:82-91.
5. + ratio. J. Bacteriol. 179:5282-5287.
6. Gasson, M. J. 1983. Plasmid complements of Streptococcus lactis NCDO 712 and other lactic streptococci after protoplast-induced curing. J. Bacteriol. 154:1-9.
7. Koebmann, B., C. Solem, and P. R. Jensen. 2005. Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis. FEBS J. 272:2292-2303.
8. 1-ATPase results in uncoupling of glycolysis from biomass production in Lactococcus lactis. Appl. Environ. Microbiol. 68:4274-4282.
9. Llanos, R. M., C. J. Harris, A. J. Hillier, and B. E. Davidson. 1993. Identification of a novel operon in Lactococcus lactis encoding three enzymes for lactic acid synthesis: phosphofructokinase, pyruvate kinase, and lactate dehydrogenase. J. Bacteriol. 175:2541-2551.
10. Melchiorsen, C. R., K. V. Jokumsen, J. Villadsen, H. Israelsen, and J. Arnau. 2002. The level of pyruvate-formate lyase controls the shift from homolactic to mixed-acid product formation in Lactococcus lactis. Appl. Microbiol. Biotechnol. 58:338-344.
11. Sjöberg, A., and B. Hähn-Hagerdal. 1989. β-Glucose-1-phosphate, a possible mediator for polysaccharide formation in maltose-assimilating Lactococcus lactis. Appl. Environ. Microbiol. 55:1549-1554.
12. Solem, C., and P. R. Jensen. 2002. Modulation of gene expression made easy. Appl. Environ. Microbiol. 68:2397-2403.
13. Solem, C., B. J. Koebmann, and P. R. Jensen. 2003. Glyceraldehyde-3-phosphate dehydrogenase has no control over glycolytic flux in Lactococcus lactis MG1363. J. Bacteriol. 185:1564-1571.
14. Takahashi, S., K. Abbe, and T. Yamada. 1982. Purification of pyruvate formate-lyase from Streptococcus mutans and its regulatory properties. J. Bacteriol. 149:1034-1040.
15. Terzaghi, B. E., and W. E. Sandine. 1975. Improved medium for lactic streptococci and their bacteriophages. Appl. Microbiol. 29:807-813.
16. Thomas, T. D., D. C. Ellwood, and M. C. Longyear. 1979. Change from homo- to heterolactic fermentation by Streptococcus lactis resulting from glucose limitation in anaerobic chemostat cultures. J. Bacteriol. 138:109-117.
17. Thomas, T. D., K. W. Turner, and V. L. Crow. 1980. Galactose fermentation by Streptococcus lactis and Streptococcus cremoris: pathways, products, and regulation. J. Bacteriol. 144:672-682.
18. van Niel, E. W. J., J. Palmfeldt, R. Martin, M. Paese, and B. Hahn-Hägerdal. 2004. Reappraisal of the regulation of lactococcal L-lactate dehydrogenase. Appl. Environ. Microbiol. 70:1843-1846.
19. Wolin, M. J. 1964. Fructose-1,6-diphosphate requirement of streptococcal lactic dehydrogenases. Science 146:775-777.