Pharmacological modulation of histone demethylase activity by a small molecule isolated from subcritical water extracts of Sasa senanensis leaves prolongs the lifespan of Drosophila melanogaster

BMC Complementary and Alternative Medicine

Volumn 12, Issue , 2012, Pages

  Nakagawa Yagi, Yuzo ^a   Sato, Yukiko ^b   Matsumoto, Emi ^c   Nakatsuka, Shin ichi ^c   Sakaki, Tsuyoshi ^d   Muramatsu, Yukiko ^a   Hara, Takaaki ^a   Aigaki, Toshiro ^b  

^a Hakuju Institute for Health Science   (Japan)

^b TOKYO METROPOLITAN UNIVERSITY   (Japan)

^c Nagara Science Co Ltd   (Japan)

^d Kyushu)   (Japan)

Author keywords

Drosophila; Histone demethylase; Lifespan extension; Traditional Japanese medicine

Indexed keywords

ANTIOXIDANT; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 8; HISTONE DEMETHYLASE; INITIATION FACTOR 4E BINDING PROTEIN 1; JUMONJI DOMAIN CONTAINING PROTEIN 2A; LYSINE SPECIFIC DEMETHYLASE; PLANT EXTRACT; PROTEIN; PROTOCATECHUALDEHYDE; RESVERATROL; SASA SENANENSIS EXTRACT; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; DRUG EXPOSURE; DRUG ISOLATION; DRUG SCREENING; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IC 50; LIFE EXTENSION; MALE; MINIMUM INHIBITORY CONCENTRATION; MODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT LEAF; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; UPREGULATION;

ANIMALS; BENZALDEHYDES; CATECHOLS; DROSOPHILA MELANOGASTER; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION; HISTONE DEMETHYLASES; HUMANS; LIFE EXPECTANCY; MALE; MODELS, ANIMAL; MODELS, MOLECULAR; PLANT EXTRACTS; PLANT LEAVES; SASA; SPECIES SPECIFICITY;

EID: 84872662251     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-12-101     Document Type: Article

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