Inhibition of hydrogen sulfide synthesis provides protection for severe acute pancreatitis rats via apoptosis pathway

Apoptosis

Volumn 18, Issue 1, 2013, Pages 28-42

  Wang, Gang ^a   Han, Bing ^a   Zhou, Haoxin ^a   Wu, Linfeng ^a   Wang, Yongwei ^a   Jia, Guang ^a   Lv, Jiachen ^a   Cheng, Zhuoxin ^a   Pan, Shangha ^b   Liu, Ji ^a   Zhou, Yinan ^a   Sun, Bei ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Death receptor pathway; Hydrogen sulfide; Mitochondrial pathway; NF B; Severe acute pancreatitis

Indexed keywords

ALDEHYDE; CASPASE 3; CASPASE 8; CASPASE 9; ENZYME; HYDROGEN SULFIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; JANUS KINASE 1; JANUS KINASE 2; MALEIC DIALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE 3; MYELOPEROXIDASE; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACINAR CELL; ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME INHIBITION; ENZYME RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SCORING SYSTEM;

ALDEHYDES; ALKYNES; ANIMALS; APOPTOSIS; CASPASES; CYSTATHIONINE GAMMA-LYASE; ENZYME INHIBITORS; GLYCINE; HYDROGEN SULFIDE; INTERLEUKIN-10; MALE; PANCREAS; PANCREATITIS, ACUTE NECROTIZING; PEROXIDASE; RATS; RATS, WISTAR; SULFIDES; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; RATTUS;

EID: 84872615294     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-012-0770-x     Document Type: Article

References (55)

1. Chen P, Sun B, Chen H, Wang G, Pan S, Kong R, Bai X, Wang S (2010) Effects of carbon monoxide releasing molecule-liberated CO on severe acute pancreatitis in rats. Cytokine 49(1):15-23
2. Escobar J, Pereda J, Arduini A, Sandoval J, Sabater L, Aparisi L, Vento M, López-Rodas G, Sastre J (2010) Role of redox signaling, protein phosphatases and histone acetylation in the inflammatory cascade in acute pancreatitis: therapeutic implications. Inflamm Allergy Drug Targets 9(2):97-108
3. Melino G, Knight RA, Nicotera P (2005) How many ways to die? How many different models of cell death? Cell Death Differ 12(Suppl 2):1457-1462
4. Criddle DN, Gerasimenko JV, Baumgartner HK, Jaffar M, Voronina S, Sutton R, Petersen OH, Gerasimenko OV (2007) Calcium signalling and pancreatic cell death: apoptosis or necrosis? Cell Death Differ 14(7):1285-1294
5. Zhang XP, Lin Q, Zhou YF (2007) Progress of study on the relationship between mediators of inflammation and apoptosis in acute pancreatitis. Dig Dis Sci 52(5):1199-1205
6. Cao Y, Adhikari S, Ang AD, Moore PK, Bhatia M (2006) Mechanism of induction of pancreatic acinar cell apoptosis by hydrogen sulfide. Am J Physiol Cell Physiol 291(3):503-510
7. Kobayashi C, Yaegaki K, Calenic B, Ishkitiev N, Imai T, Ii H, Aoyama I, Kobayashi H, Izumi Y, Haapasalo M (2011) Hydrogen sulfide causes apoptosis in human pulp stem cells. J Endod 37(4):479-484
8. Chen H, Sun B, Pan S, Jiang H, Sun X (2009) Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo. Anticancer Drugs 20(2):131-140
9. McHugh P, Turina M (2006) Apoptosis and necrosis: a review for surgeons. Surg Infect (Larchmt) 7(1):53-68
10. Takeyama Y (2005) Significance of apoptotic cell death in systemic complications with severe acute pancreatitis. J Gastroenterol 40(1):1-10
11. Wagner F, Asfar P, Calzia E, Radermacher P, Szabó C (2009) Bench-to-bedside review: hydrogen sulfide - the third gaseous transmitter: applications for critical care. Crit Care 13(3):213
12. Bhatia M, Sidhapuriwala JN, Ng SW, Tamizhselvi R, Moochhala SM (2008) Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis. J Cell Mol Med 12(2):580-590
13. Tamizhselvi R, Shrivastava P, Koh YH, Zhang H, Bhatia M (2011) Preprotachykinin-A gene deletion regulates hydrogen sulfide-induced toll-like receptor 4 signaling pathway in cerulein-treated pancreatic acinar cells. Pancreas 40(3):444-452
14. Bhatia M, Wong FL, Fu D, Lau HY, Moochhala SM, Moore PK (2005) Role of hydrogen sulfide in acute pancreatitis and associated lung injury. FASEB J 19(6):623-625
15. Gu X, Zhu YZ (2011) Therapeutic applications of organosulfur compounds as novel hydrogen sulfide donors and/or mediators. Expert Rev Clin Pharmacol 4(1):123-133
16. Hegde A, Bhatia M (2011) Hydrogen sulfide in inflammation: friend or foe? Inflamm Allergy Drug Targets 10(2):118-122
17. Whiteman M, Winyard PG (2011) Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising. Expert Rev Clin Pharmacol 4(1):13-32
18. Tamizhselvi RMP, Bhatia M (2007) Hydrogen sulfide acts as a mediator of inflammation in acute pancreatitis: in vitro studies using isolated mouse pancreatic acinar cells. J Cell Mol Med 11(2):315-326
19. Tamizhselvi R, Koh YH, Sun J, Zhang H, Bhatia M (2010) Hydrogen sulfide induces ICAM-1 expression and neutrophil adhesion to caerulein-treated pancreatic acinar cells through NF-kappaB and Src-family kinases pathway. Exp Cell Res 316(9):1625-1636
20. Biermann J, Lagrèze WA, Schallner N, Schwer CI, Goebel U (2011) Inhalative preconditioning with hydrogen sulfide attenuated apoptosis after retinal ischemia/reperfusion injury. Mol Vis 17:1275-1286
21. Adhikari S, Bhatia M (2008) H2S-induced pancreatic acinar cell apoptosis is mediated via JNK and p38 MAP kinase. J Cell Mol Med 12(4):1374-1383
22. Wang G, Sun B, Zhu H, Gao Y, Li X, Xue D, Jiang H (2010) Protective effects of emodin combined with danshensu on experimental severe acute pancreatitis. Inflamm Res 59(6):479-488
23. Kang K, Zhao M, Jiang H, Tan G, Pan S, Sun X (2009) Role of hydrogen sulfide in hepatic ischemia-reperfusion-induced injury in rats. Liver Transpl 15(10):1306-1314
24. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 25(4):402-408
25. Wang G, Sun B, Gao Y, Meng QH, Jiang HC (2007) The effect of emodin-assisted early enteral nutrition on severe acute pancreatitis and secondary hepatic injury. Mediators Inflamm 2007:29638
26. Kusske AM, Rongione AJ, Ashley SW, McFadden DW, Reber HA (1996) Interleukin-10 prevents death in lethal necrotizing pancreatitis in mice. Surgery 120(2):284-288
27. Wang YW, Wang SJ, Zhou YN, Pan SH, Sun B (2012) Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer both in vitro and in vivo. J Cancer Res Clin Oncol 138(5):785-797
28. Tan G, Pan S, Li J, Dong X, Kang K, Zhao M, Jiang X, Kanwar JR, Qiao H, Jiang H, Sun X (2011) Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats. PLoS ONE 6(10):e25943
29. Thrower E, Husain S, Gorelick F (2008) Molecular basis for pancreatitis. Curr Opin Gastroenterol 24(5):580-585
30. Guzman EA, Rudnicki M (2006) Intricacies of host response in acute pancreatitis. J Am Coll Surg 202(3):509-519
31. Dawra R, Sah RP, Dudeja V, Rishi L, Talukdar R, Garg P, Saluja AK (2011) Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis. Gastroenterology 141(6):2210-2217
32. Criddle DN, Gillies S, Baumgartner-Wilson HK, Jaffar M, Chinje EC, Passmore S, Chvanov M, Barrow S, Gerasimenko OV, Tepikin AV, Sutton R, Petersen OH (2006) Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells. J Biol Chem 281(52):40485-40492
33. Gukovskaya AS, Vaquero E, Zaninovic V, Gorelick FS, Lusis AJ, Brennan ML, Holland S, Pandol SJ (2002) Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis. Gastroenterology 122(4):974-984
34. Gukovskaya AS, Pandol SJ (2004) Cell death pathways in pancreatitis and pancreatic cancer. Pancreatology 4(6):567-586
35. Booth DM, Murphy JA, Mukherjee R, Awais M, Neoptolemos JP, Gerasimenko OV, Tepikin AV, Petersen OH, Sutton R, Criddle DN (2011) Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells. Gastroenterology 140(7):2116-2125
36. Bhatia M, Wallig MA, Hofbauer B, Lee HS, Frossard JL, Steer ML, Saluja AK (1998) Induction of apoptosis in pancreatic acinar cells reduces the severity of acute pancreatitis. Biochem Biophys Res Commun 246(2):476-483
37. Mareninova OA, Sung KF, Hong P, Lugea A, Pandol SJ, Gukovsky I, Gukovskaya AS (2006) Cell death in pancreatitis: caspases protect from necrotizing pancreatitis. J Biol Chem 281(6):3370-3381
38. Nakka VP, Gusain A, Mehta SL, Raghubir R (2008) Molecular mechanisms of apoptosis in cerebral ischemia: multiple neuroprotective opportunities. Mol Neurobiol 37(1):7-38
39. Escobar J, Pereda J, Arduini A, Sandoval J, Sabater L, Aparisi L, López-Rodas G, Sastre J (2009) Cross-talk between oxidative stress and pro-inflammatory cytokines in acute pancreatitis: a key role for protein phosphatases. Curr Pharm Des 15(26):3027-3042
40. Norman J (1998) The role of cytokines in the pathogenesis of acute pancreatitis. Am J Surg 175(1):76-83
41. Malleo G, Mazzon E, Siriwardena AK, Cuzzocrea S (2007) Role of tumor necrosis factor-alpha in acute pancreatitis: from biological basis to clinical evidence. Shock 28(2):130-140
42. Wang G, Sun B, Gao Y, Meng QH, Jiang HC (2008) An experimental study of emodin assisted early enteral nutrition for the treatment of severe acute pancreatitis. Hepatogastroenterology 55(81):33-40
43. Keceli M, Kucuk C, Sozuer E, Kerek M, Ince O, Arar M (2005) The effect of interleukin-10 on acute pancreatitis induced by cerulein in a rat experimental model. J Invest Surg 18(1):7-12
44. Dagvadorj J, Naiki Y, Tumurkhuu G, Hassan F, Islam S, Koide N, Mori I, Yoshida T, Yokochi T (2008) Interleukin-10 inhibits tumor necrosis factor-alpha production in lipopolysaccharide-stimulated RAW 264.7 cells through reduced MyD88 expression. Innate Immun 14(2):109-115
45. Rakonczay Z Jr, Hegyi P, Takács T, McCarroll J, Saluja AK (2008) The role of NF-kappaB activation in the pathogenesis of acute pancreatitis. Gut 57(2):259-267
46. Kong R, Sun B, Jiang H, Pan S, Chen H, Wang S, Krissansen GW, Sun X (2010) Downregulation of nuclear factor-kappaB p65 subunit by small interfering RNA synergizes with gemcitabine to inhibit the growth of pancreatic cancer. Cancer Lett 291(1):90-98
47. Salminen A, Ojala J, Kaarniranta K (2011) Apoptosis and aging: increased resistance to apoptosis enhances the aging process. Cell Mol Life Sci 68(6):1021-1031
48. Gukovsky I, Reyes CN, Vaquero EC, Gukovskaya AS, Pandol SJ (2003) Curcumin ameliorates ethanol and nonethanol experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol 284(1):G85-G95
49. Keshet Y, Seger R (2010) The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions. Methods Mol Biol 661:3-38
50. Yang X, Zhou G, Ren T, Li H, Zhang Y, Yin D, Qian H, Li Q (2012) β-Arrestin prevents cell apoptosis through pro-apoptotic ERK1/2 and p38 MAPKs and anti-apoptotic Akt pathways. Apoptosis 17(9):1019-1026
51. Escobar J, Pereda J, López-Rodas G, Sastre J (2012) Redox signaling and histone acetylation in acute pancreatitis. Free Radic Biol Med 52(5):819-837
52. Junttila MR, Li SP, Westermarck J (2008) Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J 22(4):954-965
53. Dabrowski A (2003) Exocrine pancreas; molecular basis for intracellular signaling, damage and protection - Polish experience. J Physiol Pharmacol 54(Suppl 3):167-181
54. Yang G, Yang W, Wu L, Wang R (2007) H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells. J Biol Chem 282(22):16567-16576
55. Zhang LM, Jiang CX, Liu DW (2009) Hydrogen sulfide attenuates neuronal injury induced by vascular dementia via inhibiting apoptosis in rats. Neurochem Res 34(11):1984-1992