Protective effects of emodin combined with danshensu on experimental severe acute pancreatitis

Inflammation Research

Volumn 59, Issue 6, 2010, Pages 479-488

  Wang, Gang ^a   Sun, Bei ^a   Zhu, Hong ^b   Gao, Yue ^c   Li, Xiurong ^d   Xue, Dongbo ^a   Jiang, Hongchi ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^d Heilongjiang Province Hospital   (China)

Author keywords

Danshensu; Emodin; Over inflammatory reaction; Oxidative stress; Severe acute pancreatitis

Indexed keywords

3 (3,4 DIHYDROXYPHENYL)LACTIC ACID; AMYLASE; EMODIN; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LACTIC ACID; MALEIC ACID; MYELOPEROXIDASE; TAUROCHOLIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ACUTE PANCREATITIS; AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASCITES FLUID; CONTROLLED STUDY; DISEASE SEVERITY; DRUG POTENTIATION; DRY WEIGHT; ENZYME ACTIVITY; FEASIBILITY STUDY; HISTOPATHOLOGY; MALE; MONOTHERAPY; NONHUMAN; PANCREAS DUCT; PROSPECTIVE STUDY; RANDOMIZATION; RAT; TISSUE SECTION; WISTAR RAT;

ALDEHYDES; ANIMALS; ASCITIC FLUID; DRUG SYNERGISM; DRUGS, CHINESE HERBAL; EDEMA; EMODIN; ENZYME INHIBITORS; INTERLEUKIN-1BETA; LACTATES; MALE; NF-KAPPA B; PANCREAS; PANCREATITIS, ACUTE NECROTIZING; PEROXIDASE; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77953321996     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-009-0152-1     Document Type: Article

References (42)

1. AP Wilmer 2001 What's new in the management of acute pancreatitis? Curr Opin Anaesthesiol 14 137 141 10.1097/00001503-200104000-00003 1:STN:280:DC%2BD28rosVyktQ%3D%3D 17016393 (Pubitemid 32240987)
2. ZG Zhou YC Zheng Y Shu WM Hu BL Tian QS Li, et al. 2003 Laparoscopic management of severe acute pancreatitis Pancreas 27 e46 e50 10.1097/00006676- 200310000-00019 14508140
3. J Granger D Remick 2005 Acute pancreatitis: models, markers, and mediators Shock 24 45 51 10.1097/01.shk.0000191413.94461.b0 1:CAS:528: DC%2BD28XptlWmsA%3D%3D 16374372
4. GJ Van Acker G Perides ER Weiss S Das PN Tsichlis ML Steer 2007 Tumor progression locus-2 is a critical regulator of pancreatic and lung inflammation during acute pancreatitis J Biol Chem 282 22140 22149 10.1074/jbc.M702225200 17537724 (Pubitemid 47195790)
5. G Wang B Sun Y Gao QH Meng HC Jiang 2008 An experimental study of emodin assisted early enteral nutrition for the treatment of severe acute pancreatitis Hepatogastroenterology 55 33 40 1:CAS:528:DC%2BD1cXkslOhu7s%3D 18507074
6. XP Zhang Y Shi L Zhang 2007 Progress in the study of therapeutic effects of traditional Chinese medicine and extracts in treating severe acute pancreatitis JOP 8 704 714 17993723
7. Z Gong Y Yuan K Lou S Tu Z Zhai J Xu 2002 Mechanisms of Chinese herb emodin and somatostatin analogs on pancreatic regeneration in acute pancreatitis in rats Pancreas 25 154 160 10.1097/00006676-200208000-00007 12142738
8. JX Wu JY Xu YZ Yuan 1997 Effects and mechanism of emodin and sandostatin on pancreatic ischemia in acute haemorrhagic necrotizing pancreatitis Zhongguo Zhong Xi Yi Jie He Za Zhi 17 356 359 1:STN:280:DyaK1M%2FotValtQ%3D%3D 9863132
9. XP Zhang ZF Li XG Liu YT Wu JX Wang KM Wang, et al. 2005 Effects of emodin and baicalein on rats with severe acute pancreatitis World J Gastroenterol 11 2095 2100 1:CAS:528:DC%2BD2MXktlWrsbg%3D 15810074
10. JX Wu JY Xu YZ Yuan 2000 Effect of emodin and sandostatin on metabolism of eicosanoids in acute necrotizing pancreatitis World J Gastroenterol 6 293 294 1:CAS:528:DC%2BD3cXjtFahs7g%3D 11819581
11. Z Li X Xia S Zhang A Zhang W Bo R Zhou 2009 Up-regulation of Toll-like receptor 4 was suppressed by emodin and baicalin in the setting of acute pancreatitis Biomed Pharmacother 63 120 128 10.1016/j.biopha.2008.01.003 1:CAS:528:DC%2BD1MXhtlSgsLg%3D 18343629
12. G Wang B Sun Y Gao QH Meng HC Jiang 2007 The effect of emodin assisted early enteral nutrition on severe acute pancreatitis and secondary hepatic injury Mediators Inflamm 2007 29638 18288270
13. H Zhang C Yu JY Jia SW Leung YL Siow RY Man, et al. 2002 Contents of four active components in different commercial crude drugs and preparations of danshen (Salvia miltiorrhiza) Acta Pharmacol Sin 23 1163 1168 1:CAS:528:DC%2BD38Xps1eisbg%3D 12466055
14. L Wu H Qiao Y Li L Li 2007 Protective roles of puerarin and Danshensu on acute ischemic myocardial injury in rats Phytomedicine 14 652 658 10.1016/j.phymed.2007.07.060 1:CAS:528:DC%2BD2sXhtlOlsL%2FL 17870452 (Pubitemid 47419302)
15. XJ Wang ZB Wang JX Xu 2005 Effect of salvianic acid A on lipid peroxidation and membrane permeability in mitochondria J Ethnopharmacol 97 441 445 10.1016/j.jep.2004.11.036 1:CAS:528:DC%2BD2MXhvVSnsLk%3D 15740878 (Pubitemid 40312316)
16. BE Muhs S Patel H Yee S Marcus P Shamamian 2003 Inhibition of matrix metalloproteinases reduces local and distant organ injury following experimental acute pancreatitis J Surg Res 109 110 117 10.1016/S0022-4804(02)00084-7 1:CAS:528:DC%2BD3sXitVKnsb0%3D 12643851 (Pubitemid 36315737)
17. AM Kusske AJ Rongione SW Ashley DW McFadden HA Reber 1996 Interleukin-10 prevents death in lethal necrotizing pancreatitis in mice Surgery 120 284 289 10.1016/S0039-6060(96)80299-6 1:STN:280:DyaK28zltVemsQ%3D%3D 8751594
18. A Kumar S Dhawan BB Aggarwal 1998 Emodin (3-methyl-1,6,8- trihydroxyanthraquinone) inhibits TNF-induced NF-kappaB activation, IkappaB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells Oncogene 17 913 918 10.1038/sj.onc.1201998 1:CAS:528:DyaK1cXlslGgtr8%3D 9780008
19. HL Li HL Chen H Li KL Zhang XY Chen XW Wang, et al. 2005 Regulatory effects of emodin on NF-kappaB activation and inflammatory cytokine expression in RAW 264.7 macrophages Int J Mol Med 16 41 47 1:CAS:528:DC%2BD2MXmt1CmtLg%3D 15942676
20. YC Kuo HC Meng WJ Tsai 2001 Regulation of cell proliferation, inflammatory cytokine production and calcium mobilization in primary human T lymphocytes by emodin from Polygonum hypoleucum Ohwi Inflamm Res 50 73 82 10.1007/s000110050727 1:CAS:528:DC%2BD3MXivFOltb0%3D 11289657 (Pubitemid 32210147)
21. M Ding TX Ye GR Zhao YJ Yuan ZX Guo 2005 Aqueous extract of Salvia miltiorrhiza attenuates increased endothelial permeability induced by tumor necrosis factor-α Int Immunopharmacol 5 1641 1651 10.1016/j.intimp.2005. 05.005 1:CAS:528:DC%2BD2MXmsVOntb0%3D 16039554 (Pubitemid 41019435)
22. M Ding YJ Yuan 2007 Study on the mechanisms of an extract of Salvia miltiorrhiza on the regulation of permeability of endothelial cells exposed to tumor necrosis factor-alpha J Pharm Pharmacol 59 1027 1033 10.1211/jpp.59.7.0016 1:CAS:528:DC%2BD2sXntl2gsLk%3D 17637199 (Pubitemid 47051085)
23. L Zhou Z Zuo MS Chow 2005 Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use J Clin Pharmacol 45 1345 1359 10.1177/0091270005282630 1:CAS:528:DC%2BD2MXhtlSjtrzL 16291709 (Pubitemid 41643896)
24. CM Cao Q Xia X Zhang WH Xu HD Jiang JZ Chen 2003 Salvia miltiorrhiza attenuates the changes in contraction and intracellular calcium induced by anoxia and reoxygenation in rat cardiomyocytes Life Sci 72 2451 2463 10.1016/S0024-3205(03)00142-5 1:CAS:528:DC%2BD3sXitV2ns7g%3D 12650853 (Pubitemid 36321817)
25. H Jiang T Ha D Wei 2001 A study on the mechanism of the biological roles of danshensu on fibroblast Zhonghua Shao Shang Za Zhi 17 36 38 1:CAS:528:DC%2BD3MXitlGjtrY%3D 11876909
26. QB Zhang KR Gu 1987 Dihydroxyacetophenone and dihydroxyphenyllactic acid increased blood flow in rat liver microcirculation Zhong Xi Yi Jie He Za Zhi 7 608 609 1:STN:280:DyaL1c7psVyhsg%3D%3D 3447762
27. L Zhu YD Shao HJ Dai JC Dong F Xue 1986 Effects of sodium beta-3,4-dihydroxyphenyl lactate and beta-phenyl lactic acid on prostacycline and thromboxane A2 contents in the plasma of rabbits after coronary artery occlusion Zhongguo Yao Li Xue Bao 7 533 536 1:CAS:528:DyaL2sXislGrtA%3D%3D 2955643
28. CZ Li 1983 Experimental study on the anticoagulative action of Danshensu Zhong Xi Yi Jie He Za Zhi 3 297 299 1:STN:280:DyaL2c%2FlsFKkug%3D%3D 6227414
29. ZT Dong WD Jiang 1982 Effect of danshensu on isolated swine coronary artery perfusion preparation (author's transl) Yao Xue Xue Bao 17 226 228 1:CAS:528:DyaL38Xks1Kjsrw%3D 7102340
30. BL Zhao W Jiang Y Zhao JW Hou WJ Xin 1996 Scavenging effects of Salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia-reperfusion injury Biochem Mol Biol Int 38 1171 1182 8739039
31. CY Wang FL Ma JT Liu JW Tian FH Fu 2007 Protective effect of salvianic acid A on acute liver injury induced by carbon tetrachloride in rats Biol Pharm Bull 30 44 47 10.1248/bpb.30.44 1:CAS:528:DC%2BD2sXjtlWmu7k%3D 17202657 (Pubitemid 46066317)
32. SM Smith RH Eng F Buccini 1986 Use of d-lactic acid measurements in the diagnosis of bacterial infections J Infect Dis 154 658 664 1:CAS:528: DyaL28XmtVGmu7k%3D 3528318
33. M Bhatia FL Wong Y Cao HY Lau J Huang P Puneet, et al. 2005 Pathophysiology of acute pancreatitis Pancreatology 5 132 144 10.1159/000085265 15849484 (Pubitemid 40754730)
34. AS Paszkowski B Rau JM Mayer P Moller HG Beger 2002 Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis Ann Surg 235 68 76 10.1097/00000658-200201000-00009 11753044 (Pubitemid 34062401)
35. N Oruc AO Ozutemiz V Yukselen D Nart HA Celik G Yuce, et al. 2004 Infliximab: a new therapeutic agent in acute pancreatitis? Pancreas 28 el el8 10.1097/00006676-200401000-00020
36. CJ Chen H Kono D Golenbock G Reed S Akira KL Rock 2007 Identification of a key pathway required for the sterile inflammatory response triggered by dying cells Nat Med 13 851 856 10.1038/nm1603 1:CAS:528:DC%2BD2sXnsFWmtrk%3D 17572686 (Pubitemid 47038190)
37. B Rau A Paszkowski S Lillich K Baumgart P Moller HG Beger 2001 Differential effects of caspase-1/interleukin-1beta-converting enzyme on acinar cell necrosis and apoptosis in severe acute experimental pancreatitis Lab Invest 81 1001 1013 1:CAS:528:DC%2BD3MXlslamtrs%3D 11454989 (Pubitemid 32645976)
38. V Gross HG Leser A Heinisch J Scholmerich 1993 Inflammatory mediators and cytokines-new aspects of the pathophysiology and assessment of severity of acute pancreatitis? Hepatogastroenterology 40 522 530 1:STN:280: DyaK2c7msVGqsg%3D%3D 7509768
39. M Bhatia M Brady S Shokuhi S Christmas JP Neoptolemos J Slavin 2000 Inflammatory mediators in acute pancreatitis J Pathol 190 117 125 10.1002/(SICI)1096-9896(200002)190:2<117::AID-PATH494>3.0.CO;2-K 1:CAS:528:DC%2BD3cXhsFartbk%3D 10657008 (Pubitemid 30082483)
40. JA Dunn C Li T Ha RL Kao W Browder 1997 Therapeutic modification of nuclear factor Kappa B binding activity and tumor necrosis factor-alpha gene expression during acute biliary pancreatitis Am Surg 63 1036 1043 1:STN:280:DyaK1c%2FlsV2lsg%3D%3D 9393250
41. XP Zhang ZJ Li DR Liu 2006 Progress in research into the mechanism of Radix salviae miltiorrhizae in treatment of acute pancreatitis Hepatobiliary Pancreat Dis Int 5 501 504 17085332
42. CB Hughes AB el-Din M Kotb LW Gaber AO Gaber 1996 Calcium channel blockade inhibits release of TNF alpha and improves survival in a rat model of acute pancreatitis Pancreas 13 22 28 10.1097/00006676-199607000-00003 1:STN:280:DyaK28znslCqsg%3D%3D 8783330