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Volumn 54, Issue SUPPL. 3, 2003, Pages 167-181

Exocrine pancreas; molecular basis for intracellular signaling, damage and protection - Polish experience

Author keywords

Apoptosis; MAP kinases; Pancreatic acinar cells; Pancreatic stellate cells; Pancreatitis; Reactive oxygen species

Indexed keywords

CHOLECYSTOKININ; EPIDERMAL GROWTH FACTOR; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

EID: 23244460378     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (45)
  • 1
    • 0029864407 scopus 로고    scopus 로고
    • Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo
    • Dabrowski A, Grady T, Logsdon CD et al. Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo. J Biol Chem 1996; 271(10): 5686-5690.
    • (1996) J Biol Chem , vol.271 , Issue.10 , pp. 5686-5690
    • Dabrowski, A.1    Grady, T.2    Logsdon, C.D.3
  • 2
    • 0030567987 scopus 로고    scopus 로고
    • Stress-activated protein kinase activation is the earliest direct correlate to the induction of secretagogue-induced pancreatitis in rats
    • Grady T, Dabrowski A, Williams JA et al. Stress-activated protein kinase activation is the earliest direct correlate to the induction of secretagogue-induced pancreatitis in rats. Biochem Biophys Res Commun 1996; 227(1): 1-7.
    • (1996) Biochem Biophys Res Commun , vol.227 , Issue.1 , pp. 1-7
    • Grady, T.1    Dabrowski, A.2    Williams, J.A.3
  • 3
    • 0029864557 scopus 로고    scopus 로고
    • Cholecystokinin stimulates formation of shc-grb2 complex in rat pancreatic acinar cells through a protein kinase C-dependent mechanism
    • Dabrowski A, VanderKuur JA, Carter-Su C et al. Cholecystokinin stimulates formation of shc-grb2 complex in rat pancreatic acinar cells through a protein kinase C-dependent mechanism. J Biol Chem 1996; 271(43): 27125-27129.
    • (1996) J Biol Chem , vol.271 , Issue.43 , pp. 27125-27129
    • Dabrowski, A.1    Vanderkuur, J.A.2    Carter-Su, C.3
  • 4
    • 0030900843 scopus 로고    scopus 로고
    • CCK activates p90rsk in rat pancreatic acini through protein kinase C
    • Bragado MJ, Dabrowski A, Groblewski GE et al. CCK activates p90rsk in rat pancreatic acini through protein kinase C. Am J Physiol 1997; 272(3 Pt 1): G401-407.
    • (1997) Am J Physiol , vol.272 , Issue.3 PART 1
    • Bragado, M.J.1    Dabrowski, A.2    Groblewski, G.E.3
  • 5
    • 0030864018 scopus 로고    scopus 로고
    • Stimulation of both CCK-A and CCK-B receptors activates MAP kinases in AR42J and receptor-transfected CHO cells
    • Dabrowski A, Detjen KM, Logsdon CD et al. Stimulation of both CCK-A and CCK-B receptors activates MAP kinases in AR42J and receptor-transfected CHO cells. Digestion 1997; 58(4): 361-367.
    • (1997) Digestion , vol.58 , Issue.4 , pp. 361-367
    • Dabrowski, A.1    Detjen, K.M.2    Logsdon, C.D.3
  • 6
    • 0030720786 scopus 로고    scopus 로고
    • Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells
    • Dabrowski A, Groblewski GE, Schafer C et al. Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells. Am J Physiol 1997; 273(5 Pt 1): C1472-1479.
    • (1997) Am J Physiol , vol.273 , Issue.5 PART 1
    • Dabrowski, A.1    Groblewski, G.E.2    Schafer, C.3
  • 7
    • 0031536705 scopus 로고    scopus 로고
    • Novel kinase signaling cascades in pancreatic acinar cells
    • Williams JA, Dabrowski A, Logsdon CD. Novel kinase signaling cascades in pancreatic acinar cells. News Physiol Sci 1997; 12: 117-121.
    • (1997) News Physiol Sci , vol.12 , pp. 117-121
    • Williams, J.A.1    Dabrowski, A.2    Logsdon, C.D.3
  • 8
    • 0036968193 scopus 로고    scopus 로고
    • Cholecystokinin activates a variety of intracellular signal transduction mechanisms in rodent pancreatic acinar cells
    • Williams JA, Sans MD, Tashiro M et al. Cholecystokinin activates a variety of intracellular signal transduction mechanisms in rodent pancreatic acinar cells. Pharmacol Toxicol 2002; 91(6): 297-303.
    • (2002) Pharmacol Toxicol , vol.91 , Issue.6 , pp. 297-303
    • Williams, J.A.1    Sans, M.D.2    Tashiro, M.3
  • 9
    • 0018033383 scopus 로고
    • Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini
    • Williams JA, Korc M, Dormer RL. Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini. Am J Physiol 1978; 235: E517-E524.
    • (1978) Am J Physiol , vol.235
    • Williams, J.A.1    Korc, M.2    Dormer, R.L.3
  • 10
    • 0027136045 scopus 로고
    • Cholecystokinin and regulation of pancreatic acinar cell function
    • Williams JA, Blevins GT. Cholecystokinin and regulation of pancreatic acinar cell function. Physiol Rev 1993; 73: 701-723.
    • (1993) Physiol Rev , vol.73 , pp. 701-723
    • Williams, J.A.1    Blevins, G.T.2
  • 11
    • 0001030641 scopus 로고
    • Stimulus-secretion coupling in pancreatic acinar cells
    • Edited by Vay Liang W. Go, et al. New York: Raven Press
    • Williams JA, Yule DI. Stimulus-secretion coupling in pancreatic acinar cells. In The pancreas: Biology, Pathobiology, and Disease, second edition. Edited by Vay Liang W. Go, et al. New York: Raven Press; 1993: 167-189.
    • (1993) The Pancreas: Biology, Pathobiology, and Disease, Second Edition , pp. 167-189
    • Williams, J.A.1    Yule, D.I.2
  • 12
    • 0030747173 scopus 로고    scopus 로고
    • Pancreatic acinar cell intracellular signaling mechanisms
    • Williams JA. Pancreatic acinar cell intracellular signaling mechanisms. Curr Opin Gastroenterol 1997; 13: 369-374.
    • (1997) Curr Opin Gastroenterol , vol.13 , pp. 369-374
    • Williams, J.A.1
  • 13
    • 0028000213 scopus 로고
    • The mitogen activated protein kinase signal transduction pathway: From the cell surface to the nucleus
    • Guan K-L. The mitogen activated protein kinase signal transduction pathway: from the cell surface to the nucleus. Cell Signal 1994; 6: 581-589.
    • (1994) Cell Signal , vol.6 , pp. 581-589
    • Guan, K.-L.1
  • 14
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger R, Krebs EG. The MAPK signaling cascade. FEBS J 1995; 9: 726-735.
    • (1995) FEBS J , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 15
    • 0029025036 scopus 로고
    • The regulation of tyrosine kinase signaling pathways by growth factor and G-protein-coupled receptors
    • Malarkey K, Belham CM, Paul A et al. The regulation of tyrosine kinase signaling pathways by growth factor and G-protein-coupled receptors. Biochem J 1995; 309: 361-375.
    • (1995) Biochem J , vol.309 , pp. 361-375
    • Malarkey, K.1    Belham, C.M.2    Paul, A.3
  • 16
    • 0028926263 scopus 로고
    • Parallel signal processing among mammalian MAPKs
    • Cano E, and Mahadevan LC. Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 1995; 20: 117-122.
    • (1995) Trends Biochem Sci , vol.20 , pp. 117-122
    • Cano, E.1    Mahadevan, L.C.2
  • 17
    • 0029900434 scopus 로고    scopus 로고
    • G protein-coupled receptors and signaling pathways regulating growth responses
    • Post GR, and Brown JH. G protein-coupled receptors and signaling pathways regulating growth responses. FASEB J 1996; 10: 741-749.
    • (1996) FASEB J , vol.10 , pp. 741-749
    • Post, G.R.1    Brown, J.H.2
  • 18
    • 0028156378 scopus 로고
    • Cholecystokinin rapidly activates mitogen-activated protein kinase in rat pancreatic acini
    • Duan RD, Williams JA. Cholecystokinin rapidly activates mitogen-activated protein kinase in rat pancreatic acini. Am J Physiol (Gastrointest Liver Physiol 30), 1994; 267: G401-G408.
    • (1994) Am J Physiol (Gastrointest Liver Physiol 30) , vol.267
    • Duan, R.D.1    Williams, J.A.2
  • 19
    • 0028835482 scopus 로고
    • Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
    • Duan R-D, Zheng C-F, Guan K-L et al. Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini. Am J Physiol (Gastrointest Liver Physiol 31), 1995; 268: G1060-G1065.
    • (1995) Am J Physiol (Gastrointest Liver Physiol 31) , vol.268
    • Duan, R.-D.1    Zheng, C.-F.2    Guan, K.-L.3
  • 20
    • 0028858632 scopus 로고
    • Oxidative stress in acute and chronic pancreatitis
    • Schoenberg MH, Birk D, Beger HG. Oxidative stress in acute and chronic pancreatitis. Am J Clin Nutr 1995; 62: 1306S-1314S.
    • (1995) Am J Clin Nutr , vol.62
    • Schoenberg, M.H.1    Birk, D.2    Beger, H.G.3
  • 21
    • 0029786105 scopus 로고    scopus 로고
    • Role of oxidative stress in the pathogenesis of acute pancreatitis
    • Sweiry JH, Mann GE. Role of oxidative stress in the pathogenesis of acute pancreatitis. Scand J Gastroenterol 1996; 31 Suppl 219: 10-15.
    • (1996) Scand J Gastroenterol , vol.31 , Issue.SUPPL. 219 , pp. 10-15
    • Sweiry, J.H.1    Mann, G.E.2
  • 22
    • 0000285572 scopus 로고
    • Evolution of pancreatitis
    • Braganza JM (ed). Manchester University Press, Manchester and New York
    • Braganza JM. Evolution of pancreatitis; pp 19-33, in Braganza JM (ed). The Pathogenesis of Pancreatitis. Manchester University Press, Manchester and New York, 1991.
    • (1991) The Pathogenesis of Pancreatitis , pp. 19-33
    • Braganza, J.M.1
  • 23
    • 0033027090 scopus 로고    scopus 로고
    • Role of oxidative stress in the pathogenesis of caerulein-induced acute pancreatitis
    • Da̧browski A, Konturek SJ, Konturek JW et al. Role of oxidative stress in the pathogenesis of caerulein-induced acute pancreatitis. Eur J Pharmacol 1999; 377: 1-11.
    • (1999) Eur J Pharmacol , vol.377 , pp. 1-11
    • Da̧browski, A.1    Konturek, S.J.2    Konturek, J.W.3
  • 24
    • 0031036917 scopus 로고    scopus 로고
    • An essential role for free radicals and derived species in signal transduction
    • Lander HM. An essential role for free radicals and derived species in signal transduction. FASEB J 1997; 11: 118-124.
    • (1997) FASEB J , vol.11 , pp. 118-124
    • Lander, H.M.1
  • 25
    • 0031000105 scopus 로고    scopus 로고
    • Superoxides relay Ras protein's oncogenic message
    • Pennisi E. Superoxides relay Ras protein's oncogenic message. Science 1997; 275: 1567-1568.
    • (1997) Science , vol.275 , pp. 1567-1568
    • Pennisi, E.1
  • 26
    • 0033743875 scopus 로고    scopus 로고
    • Reactive oxygen species activate mitogen-activated protein kinases in pancreatic acinar cells
    • Dabrowski A, Boguslowicz C, Dabrowska M et al. Reactive oxygen species activate mitogen-activated protein kinases in pancreatic acinar cells. Pancreas 2000; 21(4): 376-384.
    • (2000) Pancreas , vol.21 , Issue.4 , pp. 376-384
    • Dabrowski, A.1    Boguslowicz, C.2    Dabrowska, M.3
  • 27
    • 0030988742 scopus 로고    scopus 로고
    • Biochemistry and pathology of radical-mediated protein oxidation
    • Dean RT, Fu S, Stocker R, Davies MJ. Biochemistry and pathology of radical-mediated protein oxidation. Biochem J 1997; 324: 1-18.
    • (1997) Biochem J , vol.324 , pp. 1-18
    • Dean, R.T.1    Fu, S.2    Stocker, R.3    Davies, M.J.4
  • 28
    • 0029955623 scopus 로고    scopus 로고
    • Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases
    • Lo YYC, Wong JMS, Cruz TF. Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases. J Biol Chem 1996; 271: 15703-15707.
    • (1996) J Biol Chem , vol.271 , pp. 15703-15707
    • Lo, Y.Y.C.1    Wong, J.M.S.2    Cruz, T.F.3
  • 29
    • 0030049439 scopus 로고    scopus 로고
    • 2. Role of cell survival following oxidant injury
    • 2. Role of cell survival following oxidant injury. J Biol Chem 1996; 271: 4138-4142.
    • (1996) J Biol Chem , vol.271 , pp. 4138-4142
    • Guyton, K.Z.1    Liu, Y.2    Gorospe, M.3
  • 30
    • 0028881770 scopus 로고
    • UV irradiation and heat shock mediate JNK activation via alternative pathways
    • Adler V, Schaffer A, Kim J et al. UV irradiation and heat shock mediate JNK activation via alternative pathways. J Biol Chem 1995; 270: 26071-26077.
    • (1995) J Biol Chem , vol.270 , pp. 26071-26077
    • Adler, V.1    Schaffer, A.2    Kim, J.3
  • 31
    • 0024602827 scopus 로고
    • Tissue destruction by neutrophils
    • Weiss SJ. Tissue destruction by neutrophils. N J Engl Med 1989; 320: 365-376.
    • (1989) N J Engl Med , vol.320 , pp. 365-376
    • Weiss, S.J.1
  • 33
    • 0033598131 scopus 로고    scopus 로고
    • Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways
    • Carpenter G. Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways. J Cell Biol 1999; 146: 697-702.
    • (1999) J Cell Biol , vol.146 , pp. 697-702
    • Carpenter, G.1
  • 34
    • 0032508660 scopus 로고    scopus 로고
    • A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini
    • Schäfer C, Ross SE, Bragado MJ et al. A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini. J Biol Chem 1998; 273: 24173-24180.
    • (1998) J Biol Chem , vol.273 , pp. 24173-24180
    • Schäfer, C.1    Ross, S.E.2    Bragado, M.J.3
  • 35
    • 0029046949 scopus 로고
    • Effect of cerulein hyperstimulation on the paracellular barrier of rat exocrine pancreas
    • Fallon MB, Gorelick FS, Anderson JM et al. Effect of cerulein hyperstimulation on the paracellular barrier of rat exocrine pancreas. Gastroenterolgy 1995; 108: 1863-1872.
    • (1995) Gastroenterolgy , vol.108 , pp. 1863-1872
    • Fallon, M.B.1    Gorelick, F.S.2    Anderson, J.M.3
  • 36
    • 0028963543 scopus 로고
    • Disassembly of rat pancreatic acinar cell cytoskeleton during supramaximal secretagogue stimulation
    • Jungerman J, Lerch MM, Weidenbach H et al. Disassembly of rat pancreatic acinar cell cytoskeleton during supramaximal secretagogue stimulation. Am J Physiol 1995; 268: G328-G338.
    • (1995) Am J Physiol , vol.268
    • Jungerman, J.1    Lerch, M.M.2    Weidenbach, H.3
  • 37
    • 0032897552 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells
    • Shimizu H, Banno Y, Sumi N et al. Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells. J Invest Dermatol 1999; 112:769-774.
    • (1999) J Invest Dermatol , vol.112 , pp. 769-774
    • Shimizu, H.1    Banno, Y.2    Sumi, N.3
  • 38
    • 0033617288 scopus 로고    scopus 로고
    • P38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389
    • Huang C, Ma W-Y, Maxiner A et al. P38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389. J Biol Chem 1999; 274: 12229-12235.
    • (1999) J Biol Chem , vol.274 , pp. 12229-12235
    • Huang, C.1    Ma, W.-Y.2    Maxiner, A.3
  • 39
    • 0033598155 scopus 로고    scopus 로고
    • Extranuclear apoptosis: The role of the cytoplasm in the execution phase
    • Mills JC, Stone NL, Pittman RN. Extranuclear apoptosis: The role of the cytoplasm in the execution phase. J Cell Biol 1999; 146: 703-707.
    • (1999) J Cell Biol , vol.146 , pp. 703-707
    • Mills, J.C.1    Stone, N.L.2    Pittman, R.N.3
  • 40
    • 0033947758 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinases in different models of pancreatic acinar cell damage
    • Dabrowski A, Tribillo I, Dabrowska MI et al. Activation of mitogen-activated protein kinases in different models of pancreatic acinar cell damage. Z Gastroenterol 2000; 38(6): 469-481.
    • (2000) Z Gastroenterol , vol.38 , Issue.6 , pp. 469-481
    • Dabrowski, A.1    Tribillo, I.2    Dabrowska, M.I.3
  • 41
    • 0029841658 scopus 로고    scopus 로고
    • The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis
    • Sandoval D, Gukovskaya A, Reavey P et al. The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis. Gastroenterology 1996; 111: 1081-1091.
    • (1996) Gastroenterology , vol.111 , pp. 1081-1091
    • Sandoval, D.1    Gukovskaya, A.2    Reavey, P.3
  • 42
    • 0032546791 scopus 로고    scopus 로고
    • Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells
    • Iordanov MS, Pribnow D, Magun JL et al. Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells. J Biol Chem 1998; 273: 15794-15803.
    • (1998) J Biol Chem , vol.273 , pp. 15794-15803
    • Iordanov, M.S.1    Pribnow, D.2    Magun, J.L.3
  • 43
    • 0027996763 scopus 로고
    • Signalling from TPA to MAP kinase requires protein kinase C, raf and MEK: Reconstitution of the signalling pathway in vitro
    • Marquardt B, Frith D, Stabel S. Signalling from TPA to MAP kinase requires protein kinase C, raf and MEK: reconstitution of the signalling pathway in vitro. Oncogene 1994; 9: 3213-3218.
    • (1994) Oncogene , vol.9 , pp. 3213-3218
    • Marquardt, B.1    Frith, D.2    Stabel, S.3
  • 45
    • 0036060344 scopus 로고    scopus 로고
    • Leptin modulates the inflammatory response in acute pancreatitis
    • Konturek PC, Jaworek J, Maniatoglou A et al. Leptin modulates the inflammatory response in acute pancreatitis. Digestion 2002; 65(3):149-160.
    • (2002) Digestion , vol.65 , Issue.3 , pp. 149-160
    • Konturek, P.C.1    Jaworek, J.2    Maniatoglou, A.3


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