Microactuator device for integrated measurement of epithelium mechanics

Biomedical Microdevices

Volumn 15, Issue 1, 2013, Pages 117-123

  Mukundan, Vikram ^a,c   Nelson, W James ^b   Pruitt, Beth L ^a  

^a Stanford University   (United States)

^b STANFORD UNIVERSITY   (United States)

^c MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

Cell mechanics; Electrostatic actuator; Epithelium; Force measurement

Indexed keywords

ADHERENT CELLS; CELL MECHANICS; CELLULAR FUNCTION; DEVICE SURFACES; EPITHELIAL CELLS; EPITHELIUM; FUNCTIONALIZED; MECHANICAL FORCE; MICROFABRICATED DEVICES; ON-CHIP ACTUATION; SINGLE CELLS;

CELLS; CYTOLOGY; ELASTICITY; ELECTROSTATIC ACTUATORS; FORCE MEASUREMENT; MECHANICAL TESTING; STIFFNESS;

BIOMECHANICS;

COLLAGEN;

ANIMAL CELL; ARTICLE; CALIBRATION; CELL ADHESION; CONTROLLED STUDY; ELECTROSTATIC ACTUATOR; EPITHELIUM CELL; FORCE; GENERAL DEVICE; HYSTERESIS; MICROTECHNOLOGY; NONHUMAN; PRIORITY JOURNAL; RIGIDITY; STRETCHING; SURFACE PROPERTY; VISCOELASTICITY;

ANIMALS; BIOMECHANICS; CALIBRATION; CELL ADHESION; DOGS; EPITHELIAL CELLS; EQUIPMENT DESIGN; MADIN DARBY CANINE KIDNEY CELLS; MECHANICAL PROCESSES; MICROTECHNOLOGY; REPRODUCIBILITY OF RESULTS; SYSTEMS INTEGRATION;

EID: 84872601118     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-012-9693-0     Document Type: Article

References (32)

1. D. Mizuno, C. Tardin, C.F. Schmidt, F.C. MacKintosh, Nonequilibrium mechanics of active cytoskeletal networks. Science 315(5810), 370-373 (2007) (Pubitemid 46175516)
2. D.E. Ingber, Mechanobiology and diseases of mechanotransduction. Ann. Med. 35(8), 564-577 (2003) (Pubitemid 38005314)
3. S. Suresh, J. Spatz, J.P. Mills, A. Micoulet, M. Dao, C.T. Lim, M. Beil, T. Seufferlein, Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria. Acta Biomater. 1(1), 15-30 (2005) (Pubitemid 43348807)
4. R.M. Hocumuth, Micropipette aspiration of living cells. J. Biomech. 33(1), 15-22 (2000)
5. M. Frisen, M. Magi, L. Sonnerup, A. Viidik, Rheological analysis of soft collagenous tissue. part ii: experimental evaluations and verifications. J. Biomech. 2(1), 21-8 (1969)
6. P.A. Janmey, D.A. Weitz, Dealing with mechanics: mechanisms of force transduction in cells. Trends Biochem. Sci. 29(7), 364-370 (2004) (Pubitemid 38968753)
7. N. Wang, J.P. Butler, D.E. Ingber, Mechanotransduction across cell surface through cytoskeleton. Science 260(5111), 1124-1127 (1993) (Pubitemid 23186787)
8. R.E. Mahaffy, S. Park, E. Gerde, J. Ka, C.K. Shih, Quantitative analysis of the viscoelastic properties of thin regions of fibroblasts using atomic force microscopy. Biophys. J. 86, 1777-17793 (2004)
9. M.T.A. Saif, C.R. Sager, S. Coyer, Functionalized biomicroelectromechanical systems sensors for force response study at local adhesion sites of single livling cells on substrates. Ann. Biomed. Eng. 31, 950-961 (2003)
10. J. Rajagopalan, A. Tofangchi, M.T.A. Saif, Drosophila neurons actively regulate axonal tension in vivo. Biophys. J. 99(10), 3208-3215 (2010)
11. O. Thoumine, A. Ott, Time scale dependent viscoelastic and contractile regimes in fibroblasts probed by microplate manipulation. J. Cell Sci. 110(17), 2109-2116 (1997) (Pubitemid 27440434)
12. A. Micoulet, J.P. Spatz, A. Ott, Mechanical response analysis and power generation by single-cell stretching. ChemPhysChem 6(4), 663-670 (2005) (Pubitemid 40579969)
13. N. Desprat, A. Richert, J. Simeon, A. Asnacios, Creep function of a single living cell. Biophys. J. 88(3), 2224-2233 (2005) (Pubitemid 40976229)
14. G. Bao, S. Suresh, Cell and molecular mechanics of biological materials. Nat. Mater. 2, 715-725 (2003)
15. K.J.V. Vliet, G. Bao, S. Suresh, The biomechanics toolbox: experimental approaches for living cells and biomolecules. Acta Mater. 51, 5881-5905 (2003)
16. O. Loh, A. Vaziri, H. Espinosa, The potential of MEMS for advancing experiments and modeling in cell mechanics. Exp. Mech. 49(1), 105-124 (2009)
17. J. Rajagopalan, M.T.A. Saif, MEMS sensors and microsystems for cell mechanobiology. J. Micromechanics Microengineering 21(5), 054002 (2011)
18. D.B. Serrell, T.L. Oreskovic, A.J. Slifka, R.L. Mahajan, D.S. Finch, A uniaxial biomems device for quantitative force-displacement measurements. Biomed. Microdevices 9(2), 267-275 (2007) (Pubitemid 46554135)
19. D.B. Serrell, J. Law, A.J. Slifka, R.L. Mahajan, D.S. Finch, A uniaxial biomems device for imaging single cell response during quantitative force-displacement measurements. Biomed. Microdevices 10(6), 883-889 (2008)
20. M.E. Chicurel, C.S. Chen, D.E. Ingber, Cellular control lies in the balance of forces. Curr. Opin. Cell Biol. 10, 232-239 (1998) (Pubitemid 28174765)
21. N.Q. Balaban, U.S. Schwarz, D. Riveline, P. Goichberg, G. Tzur, I. Sabanay, D. Mahalu, S. Safran, A. Bershadsky, L. Addadi, B. Geiger, Force and focal adhesion assebly: a close relationship studied using elastic micropatterned substrates. Nat. Cell Biol. 3, 466-427 (2001) (Pubitemid 32422082)
22. N. Chronis, L.P. Lee, Electrothermally activated su-8 microgripper for single cell manipulation in solution. J. Microeletromech. Sys. 14(4), 857-863 (2005) (Pubitemid 41488605)
23. Y. Sun, K.-T. Wan, K.P. Roberts, J.C. Bischof, B.J. Nelson, Mechanical property characterization of mouse zona pellucida. IEEE Trans. NanoBioSci. 2(4), 279-286 (2003)
24. Y. Sun, B. Nelson, M.A. Greminger, Investigating protein structure change in the zona pellucida with a microrobotic system. Int. J. Rob. Res. 24(2-3), 211-208 (2004)
25. T.L. Sounart, T.A. Michalske, K.R. Zavadil, Frequency-dependent electrostatic actuation in microfluidic mems. J. Microeletromech. Sys. 14(1), 125-133 (2005) (Pubitemid 40274561)
26. V. Mukundan, B.L. Pruitt, Mems electrostatic actuation in conducting biological media. J. Microeletromech. Sys. 18(2), 405-413 (2009)
27. C. Brunner, A. Niendorf, J.A. Kas, Passive and active single-cell biomechanics: a new perspective in cancer diagnosis. Soft Matter 5, 2171-2178 (2009)
28. V. Mukundan, P. Ponce, H.E. Butterfield, B.L. Pruitt, Modeling and characterization of electrostatic comb-drive actuators in conducting liquid media. J. Micromechanics Microengineering 19(065008), 9 (2009)
29. R. Legtenberg, A.W. Groeneveld, M. Elwenspoek, Comb-drive actuators for large displacements. J. Micromechanics Microengineering 6, 320-329 (1996) (Pubitemid 126607103)
30. N.A. Burnham, X. Chen, C.S. Hodges, G.A. Matei, E.J. Thoreson, C.J. Roberts, M.C. Davies, S.J.B. Tendler, Comparison of calibration methods for atomic-force microscopy cantilevers. Nanotechnology 14, 1-6 (2003)
31. P. Fernandez, A. Ott, Single cell mechanics: stress stiffening and kinematic hardening. Phys. Rev. Lett. 100(23), 238102 (2008)
32. Y.C. Fung, Biomechanics: Mechanical Properties of Living Tissues. Springer, New York (1993)