Dealing with mechanics: Mechanisms of force transduction in cells

Trends in Biochemical Sciences

Volumn 29, Issue 7, 2004, Pages 364-370

  Janmey, Paul A ^a   Weitz, David A ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANE; CELL STRUCTURE; CYTOSKELETON; FLOW KINETICS; FORCE; HUMAN; LIPID BILAYER; MECHANICAL STIMULATION; MECHANOTRANSDUCTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PURIFICATION; REVIEW; RIGIDITY; SHEAR STRESS; SOFT TISSUE; VISCOELASTICITY;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CELL PHYSIOLOGY; ELASTICITY; HUMANS; MECHANOTRANSDUCTION, CELLULAR; RHEOLOGY; STRESS, MECHANICAL; VISCOSITY;

EID: 3242796694     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2004.05.003     Document Type: Review

References (81)

1. Ingber D.E. Mechanobiology and diseases of mechanotransduction. Ann. Med. 35:2003;564-577
2. Cogoli A., et al. Cell sensitivity to gravity. Science. 225:1984;228-230
3. Heidemann S.R., Buxbaum R.E. Mechanical tension as a regulator of axonal development. Neurotoxicology. 15:1994;95-107
4. Smith D.H., et al. A new strategy to produce sustained growth of central nervous system axons: continuous mechanical tension. Tissue Eng. 7:2001;131-139
5. Wang J., et al. Transcriptional regulation of a contractile gene by mechanical forces applied through integrins in osteoblasts. J. Biol. Chem. 277:2002;22889-22895
6. Passerini A.G., et al. Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta. Proc. Natl. Acad. Sci. U. S. A. 101:2004;2482-2487
7. Pelham R.J. Jr, Wang Y. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl. Acad. Sci. U. S. A. 94:1997;13661-13665
8. Flanagan L.A., et al. Neurite branching on deformable substrates. NeuroReport. 13:2002;2411-2415
9. Grodzinsky A.J., et al. Cartilage tissue remodeling in response to mechanical forces. Annu. Rev. Biomed. Eng. 2:2000;691-713
10. Ehrlich P.J., Lanyon L.E. Mechanical strain and bone cell function: a review. Osteoporos. Int. 13:2002;688-700
11. Dewey C.F. Jr, et al. The dynamic response of vascular endothelial cells to fluid shear stress. J. Biomech. Eng. 103:1981;177-185
12. Garcia-Cardena G., et al. Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proc. Natl. Acad. Sci. U. S. A. 98:2001;4478-4485
13. Fukuda S., Schmid-Schonbein G.W. Regulation of CD18 expression on neutrophils in response to fluid shear stress. Proc. Natl. Acad. Sci. U. S. A. 100:2003;13152-13157
14. Ohura N., et al. Global analysis of shear stress-responsive genes in vascular endothelial cells. J. Atheroscler. Thromb. 10:2003;304-313
15. Waters C.M., et al. Cellular biomechanics in the lung. Am. J. Physiol. Lung Cell. Mol. Physiol. 283:2002;L503-L509
16. Ingber D.E. Tensegrity I. Cell structure and hierarchical systems biology. J. Cell Sci. 116:2003;1157-1173
17. Maniotis A.J., et al. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc. Natl. Acad. Sci. U. S. A. 94:1997;849-854
18. Allemand J.F., et al. Stretching DNA and RNA to probe their interactions with proteins. Curr. Opin. Struct. Biol. 13:2003;266-274
19. Glogauer M., et al. Calcium ions and tyrosine phosphorylation interact coordinately with actin to regulate cytoprotective responses to stretching. J. Cell Sci. 110:1997;11-21
20. 2+ entry. J. Cell Sci. 117:2004;85-92
21. D'Addario M., et al. Interaction of p38 and Sp1 in a mechanical force-induced, β1 integrin-mediated transcriptional circuit that regulates the actin-binding protein filamin-A. J. Biol. Chem. 277:2002;47541-47550
22. Wang H.B., et al. Focal adhesion kinase is involved in mechanosensing during fibroblast migration. Proc. Natl. Acad. Sci. U. S. A. 98:2001;11295-11300
23. von Wichert G., et al. RPTP-α acts as a transducer of mechanical force on αv/β3-integrin-cytoskeleton linkages. J. Cell Biol. 161:2003;143-153
24. von Wichert G., et al. Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2. EMBO J. 22:2003;5023-5035
25. Oberhauser A.F., et al. The mechanical hierarchies of fibronectin observed with single-molecule AFM. J. Mol. Biol. 319:2002;433-447
26. Gao M., et al. Structure and functional significance of mechanically unfolded fibronectin type III1 intermediates. Proc. Natl. Acad. Sci. U. S. A. 100:2003;14784-14789
27. Jiang G., et al. Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin. Nature. 424:2003;334-337
28. Riveline D., et al. Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J. Cell Biol. 153:2001;1175-1186
29. Galbraith C.G., et al. The relationship between force and focal complex development. J. Cell Biol. 159:2002;695-705
30. Sampath R., et al. Cytoskeletal interactions with the leukocyte integrin β2 cytoplasmic tail. Activation-dependent regulation of associations with talin and α-actinin. J. Biol. Chem. 273:1998;33588-33594
31. Steimle P.A., et al. Polyphosphoinositides inhibit the interaction of vinculin with actin filaments. J. Biol. Chem. 274:1999;18414-18420
32. Gilmore A.P., Burridge K. Cell adhesion. Cryptic sites in vinculin. Nature. 373:1995;197
33. Yin H.L., Janmey P.A. Phosphoinositide regulation of the actin cytoskeleton. Annu. Rev. Physiol. 65:2003;761-789
34. Giannone G., et al. Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation. J. Cell Biol. 163:2003;409-419
35. Sawada Y., Sheetz M.P. Force transduction by Triton cytoskeletons. J. Cell Biol. 156:2002;609-615
36. Davies P.F., et al. Hemodynamics and the focal origin of atherosclerosis: a spatial approach to endothelial structure, gene expression, and function. Ann. N.Y. Acad. Sci. 947:2001;7-17
37. Helmke B.P., Davies P.F. The cytoskeleton under external fluid mechanical forces: hemodynamic forces acting on the endothelium. Ann. Biomed. Eng. 30:2002;284-296
38. Hu S., et al. Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. Am. J. Physiol. Cell Physiol. 285:2003;C1082-C1090
39. Cantor R.S. The influence of membrane lateral pressures on simple geometric models of protein conformational equilibria. Chem. Phys. Lipids. 101:1999;45-56
40. Cantor R.S. Solute modulation of conformational equilibria in intrinsic membrane proteins: apparent "Cooperativity" without binding. Biophys. J. 77:1999;2643-2647
41. Perozo E., et al. Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating. Nat. Struct. Biol. 9:2002;696-703
42. Gullingsrud J., Schulten K. Gating of MscL studied by steered molecular dynamics. Biophys. J. 85:2003;2087-2099
43. Colombo G., et al. Simulation of MscL gating in a bilayer under stress. Biophys. J. 84:2003;2331-2337
44. Baumgart T., et al. Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension. Nature. 425:2003;821-824
45. Brumm T., et al. The effect of increasing membrane curvature on the phase transition and mixing behavior of a dimyristoyl-sn-glycero-3- phosphatidylcholine/distearoyl-sn-glycero-3-phosphatidylcholine lipid mixture as studied by Fourier transform infrared spectroscopy and differential scanning calorimetry. Biophys. J. 70:1996;1373-1379
46. Rand R.P., et al. Membrane curvature, lipid segregation, and structural transitions for phospholipids under dual-solvent stress. Biochemistry. 29:1990;76-87
47. Corey D.P. New TRP channels in hearing and mechanosensation. Neuron. 39:2003;585-588
48. Clapham D.E., et al. The TRP ion channel family. Nat. Rev. Neurosci. 2:2001;387-396
49. McNeil P.L., Steinhardt R.A. Plasma membrane disruption: repair, prevention, adaptation. Annu. Rev. Cell Dev. Biol. 19:2003;697-731
50. Chen C.S., et al. Geometric control of cell life and death. Science. 276:1997;1425-1428
51. Tschumperlin, D.J., et al. Mechanotransduction through growth-factor shedding into the extracellular space. Nature 429, 83-86.
52. Harris A.K., et al. Silicone rubber substrata: a new wrinkle in the study of cell locomotion. Science. 208:1980;177-179
53. Schwarz U.S., et al. Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization. Biophys. J. 83:2002;1380-1394
54. Galbraith C.G., Sheetz M.P. A micromachined device provides a new bend on fibroblast traction forces. Proc. Natl. Acad. Sci. U. S. A. 94:1997;9114-9118
55. Tan J.L., et al. Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proc. Natl. Acad. Sci. U. S. A. 100:2003;1484-1489
56. Boulbitch A., et al. Shape instability of a biomembrane driven by a local softening of the underlying actin cortex. Phys. Rev. E. 62:2000;3974-3985
57. Luby-Phelps K., Taylor D. Subcellular compartmentalization by local differentiation of cytoplasmic structure. Cell Motil. Cytoskeleton. 10:1988;28-37
58. Glogauer M., et al. The role of actin-binding protein 280 in integrin-dependent mechanoprotection. J. Biol. Chem. 273:1998;1689-1698
59. D'Addario M., et al. Cytoprotection against mechanical forces delivered through β1 integrins requires induction of filamin A. J. Biol. Chem. 276:2001;31969-31977
60. Fabry B., Fredberg J.J. Remodeling of the airway smooth muscle cell: are we built of glass? Respir. Physiol. Neurobiol. 137:2003;109-124
61. Fabry B., et al. Scaling the microrheology of living cells. Phys. Rev. Lett. 87:2001;148102
62. Tseng Y., et al. Micromechanical mapping of live cells by multiple-particle-tracking microrheology. Biophys. J. 83:2002;3162-3176
63. Alcaraz J., et al. Microrheology of human lung epithelial cells measured by atomic force microscopy. Biophys. J. 84:2003;2071-2079
64. Chen D.T., et al. Rheological microscopy: local mechanical properties from microrheology. Phys. Rev. Lett. 90:2003;108301
65. Gardel M.L., et al. Microrheology of entangled F-actin solutions. Phys. Rev. Lett. 91:2003;158302
66. Lau A.W., et al. Microrheology, stress fluctuations, and active behavior of living cells. Phys. Rev. Lett. 91:2003;198101
67. Keller M., et al. Slow filament dynamics and viscoelasticity in entangled and active actin networks. Philos. Trans. R. Soc. Lond. Ser. A. 361:2003;699-711
68. Wachsstock D.H., et al. Cross-linker dynamics determine the mechanical properties of actin gels. Biophys. J. 66:1994;801-809
69. Janmey P.A., et al. The mechanical properties of actin gels. Elastic modulus and filament motions. J. Biol. Chem. 269:1994;32503-32513
70. MacKintosh F.C., et al. Elasticity of semiflexible biopolymer networks. Phys. Rev. Lett. 75:1995;4425-4428
71. Satcher R.L. Jr, Dewey C.F. Jr. Theoretical estimates of mechanical properties of the endothelial cell cytoskeleton. Biophys. J. 71:1996;109-118
72. Janmey P.A., et al. Viscoelastic properties of vimentin compared with other filamentous biopolymer networks. J. Cell Biol. 113:1991;155-160
73. Freundlich H., Seifriz W. Über die Elastizität von Sollen und Gelen. Z. Phys. Chem. 104:1922;233-261
74. Puig-De-Morales M., et al. Measurement of cell microrheology by magnetic twisting cytometry with frequency domain demodulation. J. Appl. Physiol. 91:2001;1152-1159
75. Bausch A.R., et al. Rapid stiffening of integrin receptor-actin linkages in endothelial cells stimulated with thrombin: a magnetic bead microrheology study. Biophys. J. 80:2001;2649-2657
76. Feneberg W., et al. Dictyostelium cells' cytoplasm as an active viscoplastic body. Eur. Biophys. J. 30:2001;284-294
77. Crocker J.C., et al. Two-point microrheology of inhomogeneous soft materials. Phys. Rev. Lett. 85:2000;888-891
78. Jones J.D., Luby-Phelps K. Tracer diffusion through F-actin: effect of filament length and cross-linking. Biophys. J. 71:1996;2742-2750
79. Luby-Phelps K. Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area. Int. Rev. Cytol. 192:2000;189-221
80. Laurent V.M., et al. Partitioning of cortical and deep cytoskeleton responses from transient magnetic bead twisting. Ann. Biomed. Eng. 31:2003;1263-1278
81. Trickey W.R., et al. The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes. J. Orthop. Res. 22:2004;131-139