메뉴 건너뛰기




Volumn 73, Issue 2, 2013, Pages 529-538

Hyperpolarized 13C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 13; GLUCOSE; LACTIC ACID; MESSENGER RNA; MONOCARBOXYLATE TRANSPORTER 4; PYRUVIC ACID; CARBON; DIAGNOSTIC AGENT;

EID: 84872588291     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-3461     Document Type: Article
Times cited : (89)

References (50)
  • 1
    • 68949183338 scopus 로고    scopus 로고
    • Incidental renal tumours
    • Patard JJ. Incidental renal tumours. Curr Opin Urol 2009;19: 454-8.
    • (2009) Curr Opin Urol , vol.19 , pp. 454-458
    • Patard, J.J.1
  • 2
    • 55649083090 scopus 로고    scopus 로고
    • Contemporary results of percutaneous biopsy of 100 small renal masses: A single center experience
    • Volpe A, Mattar K, Finelli A, Kachura JR, Evans AJ, Geddie WR, et al. Contemporary results of percutaneous biopsy of 100 small renal masses: a single center experience. J Urol 2008;180: 2333-7.
    • (2008) J Urol , vol.180 , pp. 2333-2337
    • Volpe, A.1    Mattar, K.2    Finelli, A.3    Kachura, J.R.4    Evans, A.J.5    Geddie, W.R.6
  • 3
    • 50949098836 scopus 로고    scopus 로고
    • The value of preoperative needle core biopsy for diagnosing benign lesions among small, incidentally detected renal masses
    • Shannon BA, Cohen RJ, de Bruto H, Davies RJ. The value of preoperative needle core biopsy for diagnosing benign lesions among small, incidentally detected renal masses. J Urol 2008;180: 1257-61.
    • (2008) J Urol , vol.180 , pp. 1257-1261
    • Shannon, B.A.1    Cohen, R.J.2    De Bruto, H.3    Davies, R.J.4
  • 4
    • 33745984492 scopus 로고    scopus 로고
    • Renal cell carcinoma recurrence after nephrectomy for localized disease: Predicting survival from time of recurrence
    • Eggener SE, Yossepowitch O, Pettus JA, Snyder ME, Motzer RJ, Russo P. Renal cell carcinoma recurrence after nephrectomy for localized disease: predicting survival from time of recurrence. J Clin Oncol 2006;24: 3101-6.
    • (2006) J Clin Oncol , vol.24 , pp. 3101-3106
    • Eggener, S.E.1    Yossepowitch, O.2    Pettus, J.A.3    Snyder, M.E.4    Motzer, R.J.5    Russo, P.6
  • 5
    • 79957965672 scopus 로고    scopus 로고
    • Active surveillance of small renal masses: Progression patterns of early stage kidney cancer
    • Jewett MA, Mattar K, Basiuk J, Morash CG, Pautler SE, Siemens DR, et al. Active surveillance of small renal masses: progression patterns of early stage kidney cancer. Eur Urol 2011;60: 39-44.
    • (2011) Eur Urol , vol.60 , pp. 39-44
    • Jewett, M.A.1    Mattar, K.2    Basiuk, J.3    Morash, C.G.4    Pautler, S.E.5    Siemens, D.R.6
  • 6
    • 67649603885 scopus 로고    scopus 로고
    • Natural history, growth kinetics, and outcomes of untreated clinically localized renal tumors under active surveillance
    • Crispen PL, Viterbo R, Boorjian SA, Greenberg RE, Chen DY, Uzzo RG. Natural history, growth kinetics, and outcomes of untreated clinically localized renal tumors under active surveillance. Cancer 2009;115: 2844-52.
    • (2009) Cancer , vol.115 , pp. 2844-2852
    • Crispen, P.L.1    Viterbo, R.2    Boorjian, S.A.3    Greenberg, R.E.4    Chen, D.Y.5    Uzzo, R.G.6
  • 7
    • 18744398453 scopus 로고    scopus 로고
    • Renal cell carcinoma 2005: New frontiers in staging, prognostication and targeted molecular therapy
    • Lam JS, Shvarts O, Leppert JT, Figlin RA, Belldegrun AS. Renal cell carcinoma 2005: new frontiers in staging, prognostication and targeted molecular therapy. J Urol 2005;173: 1853-62.
    • (2005) J Urol , vol.173 , pp. 1853-1862
    • Lam, J.S.1    Shvarts, O.2    Leppert, J.T.3    Figlin, R.A.4    Belldegrun, A.S.5
  • 8
    • 80052265588 scopus 로고    scopus 로고
    • Prognostic factors and predictive models in renal cell carcinoma: A contemporary review
    • Sun M, Shariat SF, Cheng C, Ficarra V, Murai M, Oudard S, et al. Prognostic factors and predictive models in renal cell carcinoma: a contemporary review. Eur Urol 2011;60: 644-61.
    • (2011) Eur Urol , vol.60 , pp. 644-661
    • Sun, M.1    Shariat, S.F.2    Cheng, C.3    Ficarra, V.4    Murai, M.5    Oudard, S.6
  • 9
    • 80053277266 scopus 로고    scopus 로고
    • Characterization of small solid renal lesions: Can benign and malignant tumors be differentiated with CT?
    • Millet I, Doyon FC, Hoa D, Thuret R, Merigeaud S, Serre I, et al. Characterization of small solid renal lesions: can benign and malignant tumors be differentiated with CT? AJR Am J Roentgenol 2011;197: 887-96.
    • (2011) AJR Am J Roentgenol , vol.197 , pp. 887-896
    • Millet, I.1    Doyon, F.C.2    Hoa, D.3    Thuret, R.4    Merigeaud, S.5    Serre, I.6
  • 10
    • 43049181754 scopus 로고    scopus 로고
    • Decreasing size at diagnosis of stage 1 renal cell carcinoma: Analysis from the National Cancer Data Base, 1993 to 2004
    • Cooperberg MR, Mallin K, Ritchey J, Villalta JD, Carroll PR, Kane CJ. Decreasing size at diagnosis of stage 1 renal cell carcinoma: analysis from the National Cancer Data Base, 1993 to 2004. J Urol 2008; 179: 2131-5.
    • (2008) J Urol , vol.179 , pp. 2131-2135
    • Cooperberg, M.R.1    Mallin, K.2    Ritchey, J.3    Villalta, J.D.4    Carroll, P.R.5    Kane, C.J.6
  • 11
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer 2004;4: 891-9.
    • (2004) Nat Rev Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 12
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science 1956;123: 309-14.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 13
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009;324: 1029-33.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 14
    • 26844461245 scopus 로고    scopus 로고
    • 'Why do tumour cells glycolyse?': From glycolysis through citrate to lipogenesis
    • Costello LC, Franklin RB. 'Why do tumour cells glycolyse?': from glycolysis through citrate to lipogenesis. Mol Cell Biochem 2005; 280: 1-8.
    • (2005) Mol Cell Biochem , vol.280 , pp. 1-8
    • Costello, L.C.1    Franklin, R.B.2
  • 16
    • 0042861598 scopus 로고    scopus 로고
    • Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect
    • Unwin RD, Craven RA, Harnden P, Hanrahan S, Totty N, Knowles M, et al. Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect. Proteomics 2003;3: 1620-32.
    • (2003) Proteomics , vol.3 , pp. 1620-1632
    • Unwin, R.D.1    Craven, R.A.2    Harnden, P.3    Hanrahan, S.4    Totty, N.5    Knowles, M.6
  • 17
    • 35448961940 scopus 로고    scopus 로고
    • HIF-1 mediates the Warburg effect in clear cell renal carcinoma
    • Semenza GL. HIF-1 mediates the Warburg effect in clear cell renal carcinoma. J Bioenerg Biomembr 2007;39: 231-4.
    • (2007) J Bioenerg Biomembr , vol.39 , pp. 231-234
    • Semenza, G.L.1
  • 18
    • 42549156713 scopus 로고    scopus 로고
    • Metastasis is promoted by a bioenergetic switch: New targets for progressive renal cell cancer
    • Langbein S, FrederiksWM,zur Hausen A, Popa J, Lehmann J, Weiss C, et al. Metastasis is promoted by a bioenergetic switch: new targets for progressive renal cell cancer. Int J Cancer 2008;122: 2422-8.
    • (2008) Int J Cancer , vol.122 , pp. 2422-2428
    • Langbein, S.1    Frederiks, W.M.2    Zur Hausen, A.3    Popa, J.4    Lehmann, J.5    Weiss, C.6
  • 19
    • 48949097374 scopus 로고    scopus 로고
    • Metabonomic profiling of renal cell carcinoma: High-resolution proton nuclear magnetic resonance spectroscopy of human serum with multivariate data analysis
    • Gao H, Dong B, Liu X, Xuan H, Huang Y, Lin D. Metabonomic profiling of renal cell carcinoma: high-resolution proton nuclear magnetic resonance spectroscopy of human serum with multivariate data analysis. Anal Chim Acta 2008;624: 269-77.
    • (2008) Anal Chim Acta , vol.624 , pp. 269-277
    • Gao, H.1    Dong, B.2    Liu, X.3    Xuan, H.4    Huang, Y.5    Lin, D.6
  • 23
    • 43949109568 scopus 로고    scopus 로고
    • Compressed sensing for resolution enhancement of hyperpolarized (13)C flyback 3D-MRSI
    • Hu S, Lustig M, Chen AP, Crane J, Kerr A, Kelley DA, et al. Compressed sensing for resolution enhancement of hyperpolarized (13)C flyback 3D-MRSI. J Magn Reson 2008;192: 258-64.
    • (2008) J Magn Reson , vol.192 , pp. 258-264
    • Hu, S.1    Lustig, M.2    Chen, A.P.3    Crane, J.4    Kerr, A.5    Kelley, D.A.6
  • 24
    • 40449116150 scopus 로고    scopus 로고
    • Current and potential applications of clinical 13C MR spectroscopy
    • Kurhanewicz J, Bok R, Nelson SJ, Vigneron DB. Current and potential applications of clinical 13C MR spectroscopy. J Nucl Med 2008; 49: 341-4.
    • (2008) J Nucl Med , vol.49 , pp. 341-344
    • Kurhanewicz, J.1    Bok, R.2    Nelson, S.J.3    Vigneron, D.B.4
  • 25
    • 33745824936 scopus 로고    scopus 로고
    • Metabolic imaging and other applications of hyperpolarized 13C1
    • Golman K, Petersson JS. Metabolic imaging and other applications of hyperpolarized 13C1. Acad Radiol 2006;13: 932-42.
    • (2006) Acad Radiol , vol.13 , pp. 932-942
    • Golman, K.1    Petersson, J.S.2
  • 26
    • 54249093810 scopus 로고    scopus 로고
    • Hyperpolarized 13C lactate, pyruvate, and alanine: Noninvasive biomarkers for prostate cancer detection and grading
    • Albers MJ, Bok R, Chen AP, Cunningham CH, Zierhut ML, Zhang VY, et al. Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading. Cancer Res 2008;68: 8607-15.
    • (2008) Cancer Res , vol.68 , pp. 8607-8615
    • Albers, M.J.1    Bok, R.2    Chen, A.P.3    Cunningham, C.H.4    Zierhut, M.L.5    Zhang, V.Y.6
  • 27
    • 72149088738 scopus 로고    scopus 로고
    • Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice
    • Zierhut ML, Yen Y, Chen AP, Bok R, Albers MJ, Zhang V, et al. Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice. J Magn Reson 2010;202: 85-92.
    • (2010) J Magn Reson , vol.202 , pp. 85-92
    • Zierhut, M.L.1    Yen, Y.2    Chen, A.P.3    Bok, R.4    Albers, M.J.5    Zhang, V.6
  • 28
    • 75749154392 scopus 로고    scopus 로고
    • Hyperpolarized (13)C spectroscopy and an NMRcompatible bioreactor system for the investigation of real-time cellular metabolism
    • Keshari KR, Kurhanewicz J, Jeffries RE, Wilson DM, Dewar BJ, Van Criekinge M, et al. Hyperpolarized (13)C spectroscopy and an NMRcompatible bioreactor system for the investigation of real-time cellular metabolism. Magn Reson Med 2010;63: 322-9.
    • (2010) Magn Reson Med , vol.63 , pp. 322-329
    • Keshari, K.R.1    Kurhanewicz, J.2    Jeffries, R.E.3    Wilson, D.M.4    Dewar, B.J.5    Van Criekinge, M.6
  • 30
    • 0021914696 scopus 로고
    • Human renal carcinoma: Characterization of five new cell lines
    • Grossman HB, Wedemeyer G, Ren LQ. Human renal carcinoma: characterization of five new cell lines. J Surg Oncol 1985;28: 237-44.
    • (1985) J Surg Oncol , vol.28 , pp. 237-244
    • Grossman, H.B.1    Wedemeyer, G.2    Ren, L.Q.3
  • 31
    • 70949105507 scopus 로고    scopus 로고
    • UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: In vitro and in vivo model of an aberrant energy metabolic pathway in human cancer
    • Yang Y, Valera VA, Padilla-Nash HM, Sourbier C, Vocke CD, Vira MA, et al. UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer. Cancer Genet Cytogenet 2010;196: 45-55.
    • (2010) Cancer Genet Cytogenet , vol.196 , pp. 45-55
    • Yang, Y.1    Valera, V.A.2    Padilla-Nash, H.M.3    Sourbier, C.4    Vocke, C.D.5    Vira, M.A.6
  • 32
    • 39149126712 scopus 로고    scopus 로고
    • Metabolic profiling, metabolomic and metabonomic procedures forNMRspectroscopy of urine, plasma, serum and tissue extracts
    • Beckonert O, Keun HC, Ebbels TM, Bundy J, Holmes E, Lindon JC, et al. Metabolic profiling, metabolomic and metabonomic procedures forNMRspectroscopy of urine, plasma, serum and tissue extracts. Nat Protoc 2007;2: 2692-703.
    • (2007) Nat Protoc , vol.2 , pp. 2692-2703
    • Beckonert, O.1    Keun, H.C.2    Ebbels, T.M.3    Bundy, J.4    Holmes, E.5    Lindon, J.C.6
  • 34
    • 0024426557 scopus 로고
    • Osmoregulation of glycerophosphorylcholine content of mammalian renal cells
    • Nakanishi T, Burg MB. Osmoregulation of glycerophosphorylcholine content of mammalian renal cells. Am J Physiol 1989;257(4 Pt 1): C795-801.
    • (1989) Am J Physiol , vol.257 , Issue.4 PART 1
    • Nakanishi, T.1    Burg, M.B.2
  • 35
    • 77955103532 scopus 로고    scopus 로고
    • Choline kinase overexpression increases invasiveness and drug resistance of human breast cancer cells
    • Shah T, Wildes F, Penet MF, Winnard PT Jr, Glunde K, Artemov D, et al. Choline kinase overexpression increases invasiveness and drug resistance of human breast cancer cells. NMR Biomed 2010;23: 633-42.
    • (2010) NMR Biomed , vol.23 , pp. 633-642
    • Shah, T.1    Wildes, F.2    Penet, M.F.3    Winnard Jr., P.T.4    Glunde, K.5    Artemov, D.6
  • 36
    • 33947127063 scopus 로고    scopus 로고
    • Phosphocholine as a biomarker of breast cancer: Molecular and biochemical studies
    • Eliyahu G, Kreizman T, Degani H. Phosphocholine as a biomarker of breast cancer: molecular and biochemical studies. Int J Cancer 2007;120: 1721-30.
    • (2007) Int J Cancer , vol.120 , pp. 1721-1730
    • Eliyahu, G.1    Kreizman, T.2    Degani, H.3
  • 37
    • 84858337992 scopus 로고    scopus 로고
    • Functional interactions between choline kinase alpha, epidermal growth factor receptor and c-Src in breast cancer cell proliferation
    • Miyake T, Parsons SJ. Functional interactions between choline kinase alpha, epidermal growth factor receptor and c-Src in breast cancer cell proliferation. Oncogene 2012;31: 1431-41.
    • (2012) Oncogene , vol.31 , pp. 1431-1441
    • Miyake, T.1    Parsons, S.J.2
  • 38
    • 0034663601 scopus 로고    scopus 로고
    • The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells
    • Dimmer KS, Friedrich B, Lang F, Deitmer JW, Broer S. The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J 2000;350(Pt 1): 219-27.
    • (2000) Biochem J , vol.350 , Issue.PART 1 , pp. 219-227
    • Dimmer, K.S.1    Friedrich, B.2    Lang, F.3    Deitmer, J.W.4    Broer, S.5
  • 39
    • 28844495466 scopus 로고    scopus 로고
    • Compartmentation of lactate originating from glycogen and glucose in cultured astrocytes
    • Sickmann HM, Schousboe A, Fosgerau K, Waagepetersen HS. Compartmentation of lactate originating from glycogen and glucose in cultured astrocytes. Neurochem Res 2005;30: 1295-304.
    • (2005) Neurochem Res , vol.30 , pp. 1295-1304
    • Sickmann, H.M.1    Schousboe, A.2    Fosgerau, K.3    Waagepetersen, H.S.4
  • 40
    • 0030058579 scopus 로고    scopus 로고
    • Metabolic compartmentation of lactate in the glucose-perfused rat heart
    • Chatham JC, Forder Jr. Metabolic compartmentation of lactate in the glucose-perfused rat heart. Am J Physiol 1996;270(1 Pt 2):H224-9.
    • (1996) Am J Physiol , vol.270 , Issue.1 PART 2
    • Chatham, J.C.1    Forder, J.R.2
  • 41
    • 77955281020 scopus 로고    scopus 로고
    • Glutamine addiction: A new therapeutic target in cancer
    • Wise DR, Thompson CB. Glutamine addiction: a new therapeutic target in cancer. Trends Biochem Sci 2010;35: 427-33.
    • (2010) Trends Biochem Sci , vol.35 , pp. 427-433
    • Wise, D.R.1    Thompson, C.B.2
  • 42
    • 44449147036 scopus 로고    scopus 로고
    • Tumor cell metabolism: Cancer's Achilles' heel
    • Kroemer G, Pouyssegur J. Tumor cell metabolism: cancer's Achilles' heel. Cancer Cell 2008;13: 472-82.
    • (2008) Cancer Cell , vol.13 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 44
    • 79958795339 scopus 로고    scopus 로고
    • Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2alpha accumulation and promotes migration and invasion
    • Sudarshan S, Shanmugasundaram K, Naylor SL, Lin S, Livi CB, O'Neill CF, et al. Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2alpha accumulation and promotes migration and invasion. PLoS ONE 2011;6:e21037.
    • (2011) PLoS ONE , vol.6
    • Sudarshan, S.1    Shanmugasundaram, K.2    Naylor, S.L.3    Lin, S.4    Livi, C.B.5    O'Neill, C.F.6
  • 45
    • 26444570010 scopus 로고    scopus 로고
    • Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations
    • Pollard PJ, Briere JJ, Alam NA, Barwell J, Barclay E, WorthamNC, et al. Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum Mol Genet 2005;14: 2231-9.
    • (2005) Hum Mol Genet , vol.14 , pp. 2231-2239
    • Pollard, P.J.1    Briere, J.J.2    Alam, N.A.3    Barwell, J.4    Barclay, E.5    Wortham, N.C.6
  • 46
    • 84860655854 scopus 로고    scopus 로고
    • Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target
    • Gerlinger M, Santos CR, Spencer-Dene B, Martinez P, Endesfelder D, Burrell RA, et al. Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target. J Pathol 2012;227: 146-56.
    • (2012) J Pathol , vol.227 , pp. 146-156
    • Gerlinger, M.1    Santos, C.R.2    Spencer-Dene, B.3    Martinez, P.4    Endesfelder, D.5    Burrell, R.A.6
  • 48
    • 77955338803 scopus 로고    scopus 로고
    • Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo
    • Wilson DM, Keshari KR, Larson PE, Chen AP, Hu S, Van Criekinge M, et al. Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo. J Magn Reson 2010;205: 141-7.
    • (2010) J Magn Reson , vol.205 , pp. 141-147
    • Wilson, D.M.1    Keshari, K.R.2    Larson, P.E.3    Chen, A.P.4    Hu, S.5    Van Criekinge, M.6
  • 49
    • 84856733755 scopus 로고    scopus 로고
    • Generating super stimulated-echoes in MRI and their application to hyperpolarized C-13 diffusion metabolic imaging
    • Larson PE, Kerr AB, Reed GD, Hurd RE, Kurhanewicz J, Pauly JM, et al. Generating super stimulated-echoes in MRI and their application to hyperpolarized C-13 diffusion metabolic imaging. IEEE Trans Med Imaging 2012;31: 265-75.
    • (2012) IEEE Trans Med Imaging , vol.31 , pp. 265-275
    • Larson, P.E.1    Kerr, A.B.2    Reed, G.D.3    Hurd, R.E.4    Kurhanewicz, J.5    Pauly, J.M.6
  • 50
    • 84855685679 scopus 로고    scopus 로고
    • Spin tagging for hyperpolarized (1)(3)C metabolic studies
    • Chen AP, Hurd RE, Cunningham CH. Spin tagging for hyperpolarized (1)(3)C metabolic studies. J Magn Reson 2012;214: 319-23.
    • (2012) J Magn Reson , vol.214 , pp. 319-323
    • Chen, A.P.1    Hurd, R.E.2    Cunningham, C.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.