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Volumn 45, Issue 3, 2013, Pages 696-705

MiR-181a promotes osteoblastic differentiation through repression of TGF-β signaling molecules

Author keywords

C2C12 cells; Calvaria; MC3T3 cells; miR 181a; Osteoblastic differentiation; TGF BMP; Tibia

Indexed keywords

ALIZARIN; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN; MICRORNA; MICRORNA 181A; MICRORNA 181B; MICRORNA 181C; RGS4 PROTEIN; SMALL UNTRANSLATED RNA; TRANSCRIPTION FACTOR GATA 6; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG;

EID: 84872575073     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.12.008     Document Type: Article
Times cited : (115)

References (58)
  • 2
    • 0035341209 scopus 로고    scopus 로고
    • TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation
    • T. Alliston, L. Choy, P. Ducy, G. Karsenty, and R. Derynck TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation EMBO Journal 20 2001 2254 2272
    • (2001) EMBO Journal , vol.20 , pp. 2254-2272
    • Alliston, T.1    Choy, L.2    Ducy, P.3    Karsenty, G.4    Derynck, R.5
  • 4
    • 33845971522 scopus 로고    scopus 로고
    • Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
    • A. Bandyopadhyay, K. Tsuji, K. Cox, B.D. Harfe, V. Rosen, and C.J. Tabin Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis PLoS Genetics 2 2006 e216
    • (2006) PLoS Genetics , vol.2 , pp. 216
    • Bandyopadhyay, A.1    Tsuji, K.2    Cox, K.3    Harfe, B.D.4    Rosen, V.5    Tabin, C.J.6
  • 5
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 6
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • C.Z. Chen, L. Li, H.F. Lodish, and D.P. Bartel MicroRNAs modulate hematopoietic lineage differentiation Science 303 2004 83 86
    • (2004) Science , vol.303 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 7
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • B.N. Davis, A.C. Hilyard, G. Lagna, and A. Hata SMAD proteins control DROSHA-mediated microRNA maturation Nature 454 2008 56 61
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 8
    • 77955484492 scopus 로고    scopus 로고
    • Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
    • B.N. Davis, A.C. Hilyard, P.H. Nguyen, G. Lagna, and A. Hata Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha Molecular Cell 39 2010 373 384
    • (2010) Molecular Cell , vol.39 , pp. 373-384
    • Davis, B.N.1    Hilyard, A.C.2    Nguyen, P.H.3    Lagna, G.4    Hata, A.5
  • 9
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • P. Ducy, R. Zhang, V. Geoffroy, A.L. Ridall, and G. Karsenty Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation Cell 89 1997 747 754
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 13
    • 40449084522 scopus 로고    scopus 로고
    • Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
    • M.J. Hilton, X. Tu, X. Wu, S. Bai, H. Zhao, and T. Kobayashi Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation Nature Medicine 14 2008 306 314
    • (2008) Nature Medicine , vol.14 , pp. 306-314
    • Hilton, M.J.1    Tu, X.2    Wu, X.3    Bai, S.4    Zhao, H.5    Kobayashi, T.6
  • 14
    • 58149503642 scopus 로고    scopus 로고
    • Protein related to DAN and cerberus (PRDC) inhibits osteoblastic differentiation and its suppression promotes osteogenesis in vitro
    • H. Ideno, R. Takanabe, A. Shimada, K. Imaizumi, R. Araki, and M. Abe Protein related to DAN and cerberus (PRDC) inhibits osteoblastic differentiation and its suppression promotes osteogenesis in vitro Experimental Cell Research 315 2009 474 484
    • (2009) Experimental Cell Research , vol.315 , pp. 474-484
    • Ideno, H.1    Takanabe, R.2    Shimada, A.3    Imaizumi, K.4    Araki, R.5    Abe, M.6
  • 15
    • 84861972028 scopus 로고    scopus 로고
    • Expression of BMP-2 and Ets1 in BMP-2-stimulated mouse pre-osteoblast differentiation is regulated by microRNA-370
    • T. Itoh, M. Ando, Y. Tsukamasa, and Y. Akao Expression of BMP-2 and Ets1 in BMP-2-stimulated mouse pre-osteoblast differentiation is regulated by microRNA-370 FEBS Letters 586 2012 1693 1701
    • (2012) FEBS Letters , vol.586 , pp. 1693-1701
    • Itoh, T.1    Ando, M.2    Tsukamasa, Y.3    Akao, Y.4
  • 16
    • 67749145694 scopus 로고    scopus 로고
    • MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5
    • T. Itoh, Y. Nozawa, and Y. Akao MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5 Journal of Biological Chemistry 284 2009 19272 19279
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 19272-19279
    • Itoh, T.1    Nozawa, Y.2    Akao, Y.3
  • 17
    • 77956254375 scopus 로고    scopus 로고
    • MicroRNA-208 modulates BMP-2-stimulated mouse preosteoblast differentiation by directly targeting V-ets erythroblastosis virus E26 oncogene homolog 1
    • T. Itoh, S. Takeda, and Y. Akao MicroRNA-208 modulates BMP-2-stimulated mouse preosteoblast differentiation by directly targeting V-ets erythroblastosis virus E26 oncogene homolog 1 Journal of Biological Chemistry 285 2010 27745 27752
    • (2010) Journal of Biological Chemistry , vol.285 , pp. 27745-27752
    • Itoh, T.1    Takeda, S.2    Akao, Y.3
  • 18
    • 68949170622 scopus 로고    scopus 로고
    • Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells
    • J. Ji, T. Yamashita, A. Budhu, M. Forgues, H.L. Jia, and C. Li Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells Hepatology 50 2009 472 480
    • (2009) Hepatology , vol.50 , pp. 472-480
    • Ji, J.1    Yamashita, T.2    Budhu, A.3    Forgues, M.4    Jia, H.L.5    Li, C.6
  • 19
    • 79960205154 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma
    • J. Ji, T. Yamashita, and X.W. Wang Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma Cell & Bioscience 1 2011 4
    • (2011) Cell & Bioscience , vol.1 , pp. 4
    • Ji, J.1    Yamashita, T.2    Wang, X.W.3
  • 22
    • 84864115273 scopus 로고    scopus 로고
    • MiR-182 is a negative regulator of osteoblast proliferation, differentiation and skeletogenesis through targeting FoxO1
    • K.M. Kim, S.J. Park, S.H. Jung, E.J. Kim, G. Jogeswar, and J. Ajita miR-182 is a negative regulator of osteoblast proliferation, differentiation and skeletogenesis through targeting FoxO1 Journal of Bone and Mineral Research 27 2012 1669 1679
    • (2012) Journal of Bone and Mineral Research , vol.27 , pp. 1669-1679
    • Kim, K.M.1    Park, S.J.2    Jung, S.H.3    Kim, E.J.4    Jogeswar, G.5    Ajita, J.6
  • 23
    • 33751197049 scopus 로고    scopus 로고
    • Regulation of osteoblast differentiation by transcription factors
    • T. Komori Regulation of osteoblast differentiation by transcription factors Journal of Cellular Biochemistry 99 2006 1233 1239
    • (2006) Journal of Cellular Biochemistry , vol.99 , pp. 1233-1239
    • Komori, T.1
  • 24
    • 67650087599 scopus 로고    scopus 로고
    • New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites
    • I. Lee, S.S. Ajay, J.I. Yook, H.S. Kim, S.H. Hong, and N.H. Kim New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites Genome Research 19 2009 1175 1183
    • (2009) Genome Research , vol.19 , pp. 1175-1183
    • Lee, I.1    Ajay, S.S.2    Yook, J.I.3    Kim, H.S.4    Hong, S.H.5    Kim, N.H.6
  • 25
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • B.P. Lewis, C.B. Burge, and D.P. Bartel Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 120 2005 15 20
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 29
    • 17644378679 scopus 로고    scopus 로고
    • Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease
    • J. Lin, S.R. Patel, X. Cheng, E.A. Cho, I. Levitan, and M. Ullenbruch Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease Nature Medicine 11 2005 387 393
    • (2005) Nature Medicine , vol.11 , pp. 387-393
    • Lin, J.1    Patel, S.R.2    Cheng, X.3    Cho, E.A.4    Levitan, I.5    Ullenbruch, M.6
  • 30
    • 33745024718 scopus 로고    scopus 로고
    • The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epithelia
    • J. Lin, S.R. Patel, M. Wang, and G.R. Dressler The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epithelia Molecular and Cellular Biology 26 2006 4577 4585
    • (2006) Molecular and Cellular Biology , vol.26 , pp. 4577-4585
    • Lin, J.1    Patel, S.R.2    Wang, M.3    Dressler, G.R.4
  • 31
    • 84864330589 scopus 로고    scopus 로고
    • MicroRNA-181a regulates local immune balance by inhibiting proliferation and immunosuppressive properties of mesenchymal stem cells
    • L. Liu, Y. Wang, H. Fan, X. Zhao, D. Liu, and Y. Hu MicroRNA-181a regulates local immune balance by inhibiting proliferation and immunosuppressive properties of mesenchymal stem cells Stem Cells 30 2012 1756 1770
    • (2012) Stem Cells , vol.30 , pp. 1756-1770
    • Liu, L.1    Wang, Y.2    Fan, H.3    Zhao, X.4    Liu, D.5    Hu, Y.6
  • 32
    • 84255200563 scopus 로고    scopus 로고
    • Building strong bones: Molecular regulation of the osteoblast lineage
    • F. Long Building strong bones: molecular regulation of the osteoblast lineage Nature Reviews Molecular Cell Biology 13 2012 27 38
    • (2012) Nature Reviews Molecular Cell Biology , vol.13 , pp. 27-38
    • Long, F.1
  • 33
    • 1842611651 scopus 로고    scopus 로고
    • Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton
    • F. Long, U.I. Chung, S. Ohba, J. McMahon, H.M. Kronenberg, and A.P. McMahon Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton Development 131 2004 1309 1318
    • (2004) Development , vol.131 , pp. 1309-1318
    • Long, F.1    Chung, U.I.2    Ohba, S.3    McMahon, J.4    Kronenberg, H.M.5    McMahon, A.P.6
  • 35
    • 1442313955 scopus 로고    scopus 로고
    • Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells
    • S. Maeda, M. Hayashi, S. Komiya, T. Imamura, and K. Miyazono Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells EMBO Journal 23 2004 552 563
    • (2004) EMBO Journal , vol.23 , pp. 552-563
    • Maeda, S.1    Hayashi, M.2    Komiya, S.3    Imamura, T.4    Miyazono, K.5
  • 36
    • 1242272082 scopus 로고    scopus 로고
    • Identification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor beta
    • M.B. Major, and D.A. Jones Identification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor beta Journal of Biological Chemistry 279 2004 5278 5287
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 5278-5287
    • Major, M.B.1    Jones, D.A.2
  • 39
    • 0042204967 scopus 로고    scopus 로고
    • Transcriptional mechanisms in osteoblast differentiation and bone formation
    • K. Nakashima, and B. de Crombrugghe Transcriptional mechanisms in osteoblast differentiation and bone formation Trends in Genetics 19 2003 458 466
    • (2003) Trends in Genetics , vol.19 , pp. 458-466
    • Nakashima, K.1    De Crombrugghe, B.2
  • 40
    • 0037330475 scopus 로고    scopus 로고
    • Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6
    • G. Nemer, and M. Nemer Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6 Developmental Biology 254 2003 131 148
    • (2003) Developmental Biology , vol.254 , pp. 131-148
    • Nemer, G.1    Nemer, M.2
  • 41
    • 0036888627 scopus 로고    scopus 로고
    • Targets of transcriptional regulation by two distinct type i receptors for transforming growth factor-beta in human umbilical vein endothelial cells
    • T. Ota, M. Fujii, T. Sugizaki, M. Ishii, K. Miyazawa, and H. Aburatani Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells Journal of Cellular Physiology 193 2002 299 318
    • (2002) Journal of Cellular Physiology , vol.193 , pp. 299-318
    • Ota, T.1    Fujii, M.2    Sugizaki, T.3    Ishii, M.4    Miyazawa, K.5    Aburatani, H.6
  • 42
    • 44849140776 scopus 로고    scopus 로고
    • Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen
    • K.L. Posey, K. Hankenson, A.C. Veerisetty, P. Bornstein, J. Lawler, and J.T. Hecht Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen American Journal of Pathology 172 2008 1664 1674
    • (2008) American Journal of Pathology , vol.172 , pp. 1664-1674
    • Posey, K.L.1    Hankenson, K.2    Veerisetty, A.C.3    Bornstein, P.4    Lawler, J.5    Hecht, J.T.6
  • 45
    • 80052965983 scopus 로고    scopus 로고
    • MicroRNAs of rat articular cartilage at different developmental stages identified by Solexa sequencing
    • J. Sun, N. Zhong, Q. Li, Z. Min, W. Zhao, and Q. Sun MicroRNAs of rat articular cartilage at different developmental stages identified by Solexa sequencing Osteoarthritis and Cartilage 19 2011 1237 1245
    • (2011) Osteoarthritis and Cartilage , vol.19 , pp. 1237-1245
    • Sun, J.1    Zhong, N.2    Li, Q.3    Min, Z.4    Zhao, W.5    Sun, Q.6
  • 46
    • 0037011062 scopus 로고    scopus 로고
    • Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta
    • M. Takekawa, K. Tatebayashi, F. Itoh, M. Adachi, K. Imai, and H. Saito Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta EMBO Journal 21 2002 6473 6482
    • (2002) EMBO Journal , vol.21 , pp. 6473-6482
    • Takekawa, M.1    Tatebayashi, K.2    Itoh, F.3    Adachi, M.4    Imai, K.5    Saito, H.6
  • 47
    • 78650305162 scopus 로고    scopus 로고
    • Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth
    • K. Takeuchi, M. Abe, M. Hiasa, A. Oda, H. Amou, and S. Kido Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth PLoS One 5 2010 e9870
    • (2010) PLoS One , vol.5 , pp. 9870
    • Takeuchi, K.1    Abe, M.2    Hiasa, M.3    Oda, A.4    Amou, H.5    Kido, S.6
  • 48
    • 54549108798 scopus 로고    scopus 로고
    • MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
    • Y. Tay, J. Zhang, A.M. Thomson, B. Lim, and I. Rigoutsos MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation Nature 455 2008 1124 1128
    • (2008) Nature , vol.455 , pp. 1124-1128
    • Tay, Y.1    Zhang, J.2    Thomson, A.M.3    Lim, B.4    Rigoutsos, I.5
  • 50
    • 14144251874 scopus 로고    scopus 로고
    • Beta ig-h3 mediates osteoblast adhesion and inhibits differentiation
    • N. Thapa, K.B. Kang, and I.S. Kim Beta ig-h3 mediates osteoblast adhesion and inhibits differentiation Bone 36 2005 232 242
    • (2005) Bone , vol.36 , pp. 232-242
    • Thapa, N.1    Kang, K.B.2    Kim, I.S.3
  • 53
    • 84862624955 scopus 로고    scopus 로고
    • MiR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2
    • J. Wei, Y. Shi, L. Zheng, B. Zhou, H. Inose, and J. Wang miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2 Journal of Cell Biology 197 2012 509 521
    • (2012) Journal of Cell Biology , vol.197 , pp. 509-521
    • Wei, J.1    Shi, Y.2    Zheng, L.3    Zhou, B.4    Inose, H.5    Wang, J.6
  • 56
    • 0242322012 scopus 로고    scopus 로고
    • Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation
    • J. Yoo, M. Ghiassi, L. Jirmanova, A.G. Balliet, B. Hoffman, and A.J. Fornace Jr. Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation Journal of Biological Chemistry 278 2003 43001 43007
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 43001-43007
    • Yoo, J.1    Ghiassi, M.2    Jirmanova, L.3    Balliet, A.G.4    Hoffman, B.5    Fornace, Jr.A.J.6
  • 57
    • 79960633240 scopus 로고    scopus 로고
    • Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1
    • J. Zhang, Q. Tu, L.F. Bonewald, X. He, G. Stein, and J. Lian Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1 Journal of Bone and Mineral Research 26 2011 1953 1963
    • (2011) Journal of Bone and Mineral Research , vol.26 , pp. 1953-1963
    • Zhang, J.1    Tu, Q.2    Bonewald, L.F.3    He, X.4    Stein, G.5    Lian, J.6
  • 58
    • 84872687459 scopus 로고    scopus 로고
    • MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling
    • J.F. Zhang, W.M. Fu, M.L. He, W.D. Xie, Q. Lv, and G. Wan MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling RNA Biology 8 2011 829 838
    • (2011) RNA Biology , vol.8 , pp. 829-838
    • Zhang, J.F.1    Fu, W.M.2    He, M.L.3    Xie, W.D.4    Lv, Q.5    Wan, G.6


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