Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma

Cell and Bioscience

Volumn 1, Issue 1, 2011, Pages

  Ji, Junfang ^a   Yamashita, Taro ^a,b   Wang, Xin W ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b KANAZAWA UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79960205154     PISSN: None     EISSN: 20453701     Source Type: Journal    
DOI: 10.1186/2045-3701-1-4     Document Type: Article

References (20)

1. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005, 55:74-108. 10.3322/canjclin.55.2.74, 15761078.
2. Budhu A, Jia HL, Forgues M, Liu CG, Goldstein D, Lam A, et al. Identification of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology 2008, 47:897-907. 10.1002/hep.22160, 18176954.
3. Yamashita T, Forgues M, Wang W, Kim JW, Ye Q, Jia H, et al. EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma. Cancer Res 2008, 68:1451-1461. 10.1158/0008-5472.CAN-07-6013, 18316609.
4. Budhu A, Forgues M, Ye QH, Jia LH, He P, Zanetti KA, et al. Prediction of venous metastases, recurrence and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. Cancer Cell 2006, 10:99-111. 10.1016/j.ccr.2006.06.016, 16904609.
5. Yamashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY, et al. EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. Gastroenterology 2009, 136:1012-1024. 10.1053/j.gastro.2008.12.004, 2828822, 19150350.
6. Ye QH, Qin LX, Forgues M, He P, Kim JW, Peng AC, et al. Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med 2003, 9:416-423. 10.1038/nm843, 12640447.
7. Branda M, Wands JR. Signal transduction cascades and hepatitis B and C related hepatocellular carcinoma. Hepatology 2006, 43:891-902. 10.1002/hep.21196, 16628664.
8. Laurent-Puig P, Legoix P, Bluteau O, Belghiti J, Franco D, Binot F, et al. Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis. Gastroenterology 2001, 120:1763-1773. 10.1053/gast.2001.24798, 11375957.
9. Ji J, Yamashita T, Budhu A, Forgues M, Jia HL, Li C, et al. Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells. Hepatology 2009, 50:472-480. 10.1002/hep.22989, 2721019, 19585654.
10. Ji J, Wang XW. New kids on the block: Diagnostic and prognostic microRNAs in hepatocellular carcinoma. Cancer Biol Ther 2009, 8:1686-1693.
11. Liu H, Fergusson MM, Castilho RM, Liu J, Cao L, Chen J, et al. Augmented Wnt signaling in a mammalian model of accelerated aging. Science 2007, 317:803-806. 10.1126/science.1143578, 17690294.
12. Yoshikawa H, Matsubara K, Zhou X, Okamura S, Kubo T, Murase Y, et al. WNT10B Functional Dualism: beta-Catenin/Tcf-dependent Growth Promotion or Independent Suppression with Deregulated Expression in Cancer. Mol Biol Cell 2007, 18:4292-4303. 10.1091/mbc.E06-10-0889, 2043567, 17761539.
13. Derksen PW, Tjin E, Meijer HP, Klok MD, MacGillavry HD, van Oers MH, et al. Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proc Natl Acad Sci USA 2004, 101:6122-6127. 10.1073/pnas.0305855101, 395933, 15067127.
14. Morin PJ, Vogelstein B, Kinzler KW. Apoptosis and APC in colorectal tumorigenesis. Proc Natl Acad Sci USA 1996, 93:7950-7954. 10.1073/pnas.93.15.7950, 38855, 8755583.
15. Yamashita T, Budhu A, Forgues M, Wang XW. Activation of hepatic stem cell marker EpCAM by Wnt-ß-catenin signaling in hepatocellular carcinoma. Cancer Research 2007, 67:10831-10839. 10.1158/0008-5472.CAN-07-0908, 18006828.
16. Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999, 398:422-426. 10.1038/18884, 10201372.
17. Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005, 434:843-850. 10.1038/nature03319, 15829953.
18. Micsenyi A, Tan X, Sneddon T, Luo JH, Michalopoulos GK, Monga SP. Beta-catenin is temporally regulated during normal liver development. Gastroenterology 2004, 126:1134-1146. 10.1053/j.gastro.2003.12.047, 15057752.
19. Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006, 127:469-480. 10.1016/j.cell.2006.10.018, 17081971.
20. Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997, 275:1787-1790. 10.1126/science.275.5307.1787, 9065402.