Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue LysB29(Nεω- carboxyheptadecanoyl) des(B30)

Biochemistry

Volumn 52, Issue 2, 2013, Pages 282-294

  Jensen, Malene Hillerup ^a,b   Wahlund, Per Olof ^b   Toft, Katrine Nørgaard ^a   Jacobsen, Jes Kristian ^b   Steensgaard, Dorte Bjerre ^b   Van De Weert, Marco ^a   Havelund, Svend ^b   Vestergaard, Bente ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ASSOCIATION REACTIONS; DICHROISM; INSULIN; LIGHT SCATTERING; LIQUID CHROMATOGRAPHY; OLIGOMERS; SIZE EXCLUSION CHROMATOGRAPHY; X RAY CRYSTALLOGRAPHY;

BUILDING BLOCKES; FIELD FLOW FRACTIONATION; INITIAL EQUILIBRIUMS; INSULIN ANALOGUES; MULTI-ANGLE LIGHT SCATTERINGS; SELF-ASSOCIATIONS; SOLUTION STRUCTURES; STRUCTURAL METHODS;

X RAY SCATTERING;

INSULIN DERIVATIVE; LYSB29 (N OMEGA CARBOXYHEPTADECANOYL)DES(B30); OLIGOMER; PHENOL; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CIRCULAR DICHROISM; DRUG STRUCTURE; FIELD FLOW FRACTIONATION; GEL PERMEATION CHROMATOGRAPHY; LIGHT SCATTERING; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

EID: 84872572711     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3008615     Document Type: Article

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