Mechanism of protracted metabolic effects of fatty acid acylated insulin, NN304, in dogs: Retention of NN304 by albumin

Diabetologia

Volumn 42, Issue 10, 1999, Pages 1254-1263

  Hamilton Wessler, M ^a   Ader, M ^a   Dea, M ^a   Moore, D ^a   Jorgensen, P N ^b   Markussen, J ^b   Bergman, R N ^c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NOVO NORDISK A S   (Denmark)

^c Dept of Physilogy and Biophysics ^*

Author keywords

Albumin binding; Fatty acid acylated insulin; Glucose turnover; Hindlimb lymph; Transendothelial transport

Indexed keywords

FATTY ACID DERIVATIVE; HUMAN INSULIN; INSULIN; INSULIN DERIVATIVE; INSULIN DETEMIR; PIG INSULIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DOG; DRUG EFFECT; DRUG HALF LIFE; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SCREENING; GLUCOSE TRANSPORT; INSULIN TREATMENT; MALE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BLOOD GLUCOSE; CARRIER PROTEINS; DOGS; EXTRACELLULAR SPACE; FATTY ACIDS, NONESTERIFIED; FEMORAL ARTERY; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; MALE; REGIONAL BLOOD FLOW; SERUM ALBUMIN;

EID: 0032845941     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051301     Document Type: Article

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