Carboxylate ions are strong allosteric ligands for the HisB10 sites of the R-state insulin hexamer

Biochemistry

Volumn 36, Issue 32, 1997, Pages 9878-9888

  Huang, Sheng Tung ^a,b   Choi, Wonjae E ^a   Bloom, Curtis ^a,c   Leuenberger, Melissa ^a   Dunn, Michael F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BRANDEIS UNIVERSITY   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANION; CARBOXYLIC ACID; COBALT; DIMER; INSULIN; LIGAND; PHENOL; PROTEIN; ZINC;

ARTICLE; BINDING SITE; LIGAND BINDING; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ALLOSTERIC SITE; CARBOXYLIC ACIDS; COBALT; HISTIDINE; HUMANS; INSULIN; KINETICS; LIGANDS; PROTEIN CONFORMATION; ZINC;

EID: 0003100023     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9701639     Document Type: Article

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