Comparison of the allosteric properties of the Co(II)- and Zn(II)- substituted insulin hexamers

Biochemistry

Volumn 37, Issue 31, 1998, Pages 10937-10944

  Bloom, Curtis R ^a,b   Wu, Nancy ^a   Dunn, Alex ^a,b   Kaarsholm, Niels C ^a,c   Dunn, Michael F ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NOVO NORDISK A S   (Denmark)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COBALT; INSULIN DERIVATIVE; ZINC;

ALLOSTERISM; ARTICLE; BINDING KINETICS; CIRCULAR DICHROISM; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; ULTRAVIOLET SPECTROSCOPY;

ALLOSTERIC SITE; COBALT; FLUORESCENT DYES; GLUTAMIC ACID; GLUTAMINE; INSULIN; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NITROBENZOATES; PARABENS; PROTEIN CONFORMATION; SPECTROPHOTOMETRY, ULTRAVIOLET; ZINC;

EID: 0032483096     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980071z     Document Type: Article

References (31)

1. Kaarsholm, N. C., Ko, H.-C., and Dunn, M. F. (1989) Biochemistry 28, 4427-4435.
2. Bloom, C. R., Choi, W. E., Brzović, P. S., Ha, J. J., Huang, S.-T., Kaarsholm, N. C., and Dunn, M. F. (1995) J. Mol. Biol. 245, 324-330.
3. Bloom, C. R., Heymann, R., Kaarsholm, N. C., and Dunn, M. F. (1997) Biochemistry 36, 12746-12758.
4. Bloom, C. R., Kaarsholm, N. C., Ha, J., and Dunn, M. F. (1997) Biochemistry 36, 12759-12765.
5. Birnbaum, D. T., Dodd, S. W., Saxberg, B. E. H., Varshavsky, A. D., and Beals, J. M. (1996) Biochemistry 35, 5366-5378.
6. Rahuel-Clermont, S., French, C. A., Kaarsholm, N. C., and Dunn, M. F. (1997) Biochemistry 36, 5837-5845.
7. Brzović, P. S., Choi, W. E., Borchardt, D., Kaarsholm, N. C. and Dunn, M. F. (1994) Biochemistry 33, 13057-13069.
8. Huang, S. T., Choi, W. E., Bloom, C. R., Leuenberger, M., and Dunn, M. F. (1997) Biochemistry 36, 9878-9888.
9. Seydoux, F., Malhotra, O. P., and Bernhard, S. A. (1974) CRC Crit. Rev. Biochem. 2, 227-257.
10. Baker, E. N., Blundell, T. L., Cutfield, J. F., Cutfield, S. M., Dodson, E. J., Dodson, G. G., Hodgkin, D. C., Hubbard, R. E., Isaacs, N. W., Reynolds, C. D., Sakabe, K., Sakabe, N., and Vijayan, N. M. (1988) Philos. Trans. R. Soc. London, Ser. B 319, 369-456.
11. Derewenda, U., Derewenda, Z., Dodson, E. J., Dodson, G. G., Reynolds, C. D., Smith, G. D., Sparks, C., and Swensen, D. (1989) Nature 338, 594-596.
12. Ciszak, E., and Smith, G. D. (1994) Biochemistry 33, 1512-1517.
13. Smith, G. D., and Dodson, G. G. (1992) Biopolymers 32, 1749-1756.
14. Smith, G. D., and Dodson, G. G. (1992) Proteins: Struct., Funct., Genet. 14, 401-408.
15. Bentley, G. A., Brange, J., Derewenda, Z., Dodson, E. J., Dodson, G. G., Markussen, J., Wilkinson, A. J., Wollmer, A., and Xaio, B. (1992) J. Mol. Biol. 228, 1163-1176.
16. Whittingham, J. L., Chaudhuri, S., Dodson, E. J., Moody, P. C. E., and Dodson, G. G. (1995) Biochemistry 34, 15553-15563.
17. Roy, M., Brader, M. L., Lee, R. W.-K., Kaarsholm, N. C., Hansen, J., and Dunn, M. F. (1989) J. Biol. Chem. 264, 19081-19085.
18. Choi, W. E., Brader, M. L., Aguilar, V., Kaarsholm, N. C., and Dunn, M. F. (1993) Biochemistry 32, 11638-11645.
19. Choi, W. E., Borchardt, D., Kaarsholm, N. C., Brzovic, P. S., and Dunn, M. F. (1996) Proteins: Struct., Funct., Genet. 26, 377-390.
20. Blundell, T., Dodson, G., Hodgkin, D., and Mercola, D. (1972) Adv. Protein Chem. 26, 279-402.
21. Smith, G. D., Swenson, D. C., Dodson, E. J., Dodson, G. G., and Reynolds, C. D. (1984) Proc. Natl. Acad. Sci. U.S.A. 81, 7093-7079.
22. Brader, M. L., Kaarsholm, N. C., Lee, W.-K., and Dunn, M. F. (1991) Biochemistry 30, 6636-6645.
23. Brader, M. L., Borchardt, D., and Dunn, M. F. (1992) J. Am. Chem. Soc. 114, 4480-4486.
24. Brader, M. L., Borchardt, D., and Dunn, M. F. (1992) Biochemistry 31, 4691-4696.
25. Brader, M. L., Kaarsholm, N. C., Harnung, S. E., and Dunn, M. F. (1997) J. Biol. Chem. 272, 1088-1094.
26. Porter, R. R. (1953) Biochem. J. 53, 320-328.
27. Oppenheimer, H. L., Labouesse, B., and Hess, G. P. (1966) J. Biol. Chem. 241, 2720-2730.
28. Fersht, A. R., and Requena, Y. (1971) J. Mol. Biol. 60, 279-290.
29. Perutz, M. F. (1989) Q. Rev. Biophys. 22, 139-236.
30. Kyte, J. (1995) Structure in Protein Chemistry, p 157, Garland Publishing Co., New York.
31. Blasie, C. A., and Berg, J. M. (1997) Biochemistry 36, 6218-6222.