Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression

Stem Cells and Development

Volumn 22, Issue 2, 2013, Pages 268-278

  Liu, Tong Ming ^a,b   Ng, Wei Ming ^a   Tan, Hwee San ^a   Vinitha, Denslin ^a   Yang, Zheng ^a   Fan, Jia Bing ^a   Zou, Yu ^a   Hui, James H ^a   Lee, Eng Hin ^a   Lim, Bing ^b,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b GENOME INSTITUTE OF SINGAPORE   (Singapore)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; MEMBRANE ANTIGEN; SMALL INTERFERING RNA; TELOMERASE REVERSE TRANSCRIPTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CELL AGING; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; DNA REPAIR; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; MITOSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CHONDROGENESIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; LENTIVIRUS; MESENCHYMAL STROMAL CELLS; MICE; MICE, NUDE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA, SMALL INTERFERING; TELOMERASE; TIME FACTORS; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN P53;

LENTIVIRUS;

EID: 84872473823     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2012.0222     Document Type: Article

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