Knockdown of p53 combined with expression of the catalytic subunit of telomerase is sufficient to immortalize primary human ovarian surface epithelial cells

Carcinogenesis

Volumn 28, Issue 1, 2007, Pages 174-182

  Yang, Gong ^a   Rosen, Daniel G ^a   Mercado Uribe, Imelda ^a   Colacino, Justin A ^a   Mills, Gordon B ^a   Bast Jr , Robert C ^a   Zhou, Chenyi ^a   Liu, Jinsong ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 18; CYTOKERATIN 8; PROTEIN P53; SMALL INTERFERING RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ARTICLE; CANCER GROWTH; CELL AGING; CELL COUNT; CELL CULTURE; CELL CYCLE REGULATION; CELL IMMORTALIZATION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBUNIT; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; IRRADIATION; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS VECTOR; SIMIAN VIRUS 40; TELOMERE;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BLOTTING, WESTERN; CATALYTIC DOMAIN; CELL AGING; CELL DIFFERENTIATION; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; FEMALE; GENETIC VECTORS; HUMANS; IMMUNOENZYME TECHNIQUES; KARYOTYPING; KERATIN-8; MICE; MICE, INBRED BALB C; MICE, NUDE; OVARY; TELOMERASE; TELOMERE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33845621580     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgl115     Document Type: Article

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