-
1
-
-
0033379680
-
Fomivirsen-a phosphorothioate oligonucleotide for the treatment of CMV retinitis
-
De Smet, M.D., Meenken, C., and Van Den Horn, G.J., Fomivirsen-a phosphorothioate oligonucleotide for the treatment of CMV retinitis. Ocul. Immunol. Inflammation, 7(3-4): 189-198, 1999.
-
(1999)
Ocul. Immunol. Inflammation
, vol.7
, Issue.3-4
, pp. 189-198
-
-
De Smet, M.D.1
Meenken, C.2
Van Den Horn, G.J.3
-
2
-
-
0032539693
-
A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics
-
SantaLucia, J., Jr., A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics. Proc. Natl. Acad. Sci. USA, 95: 1460-1465, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1460-1465
-
-
SantaLucia, J.1
-
3
-
-
14344263974
-
Peroxide-mediated desulfurization of phosphorothioate oligonucleotides and its prevention
-
Krotz, A.H., Mehta, R.C., and Hardee, G.E., Peroxide-mediated desulfurization of phosphorothioate oligonucleotides and its prevention. J. Pharm. Sci., 94: 341-352, 2005.
-
(2005)
J. Pharm. Sci.
, vol.94
, pp. 341-352
-
-
Krotz, A.H.1
Mehta, R.C.2
Hardee, G.E.3
-
4
-
-
18844455464
-
Second generation of antisense oligonucleotides: From nuclease resistance to biological efficacy in animals
-
Altmann, K.-H. et al., Second generation of antisense oligonucleotides: from nuclease resistance to biological efficacy in animals. Chimia, 50: 168-176, 1996.
-
(1996)
Chimia
, vol.50
, pp. 168-176
-
-
Altmann, K.-H.1
-
5
-
-
10744226217
-
Pharmacokinetics of a tumor necrosis factor-α phosphorothioate 2′-O-(2-methoxyethyl) modified antisense oligonucleotide: Comparison across species
-
Geary, R.S. et al., Pharmacokinetics of a tumor necrosis factor-α phosphorothioate 2′-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species. Drug Metab. Dispos., 31(11): 1419-1428, 2003.
-
(2003)
Drug Metab. Dispos.
, vol.31
, Issue.11
, pp. 1419-1428
-
-
Geary, R.S.1
-
6
-
-
0036896204
-
Phase I trial of ISIS 104838, a 2′-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-α
-
Sewell, K.L. et al., Phase I trial of ISIS 104838, a 2′-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-α. J. Pharmacol.Exp. Ther., 303(3): 1334-1343, 2002.
-
(2002)
J. Pharmacol.Exp. Ther.
, vol.303
, Issue.3
, pp. 1334-1343
-
-
Sewell, K.L.1
-
7
-
-
0029035114
-
Transport of small molecules through the blood-brain barrier: Biology and methodology
-
Pardridge, W.M., Transport of small molecules through the blood-brain barrier: biology and methodology. Adv. Drug Delivery Rev., 15(1-3): 5-36, 1995.
-
(1995)
Adv. Drug Delivery Rev.
, vol.15
, Issue.1-3
, pp. 5-36
-
-
Pardridge, W.M.1
-
8
-
-
0030757089
-
Critical issues in the antisense inhibition of brain gene expression in vivo: Experiences targeting the 5-HT1A receptor
-
Le Corre, S.M. et al., Critical issues in the antisense inhibition of brain gene expression in vivo: experiences targeting the 5-HT1A receptor. Neurochem. Int., 31(3): 349-362, 1997.
-
(1997)
Neurochem. Int.
, vol.31
, Issue.3
, pp. 349-362
-
-
Le Corre, S.M.1
-
9
-
-
0027298897
-
Stability, clearance, and disposition of intraventricularly administered oligodeoxynucleotides: Implications for therapeutic application within the central nervous system
-
Whitesell, L. et al., Stability, clearance, and disposition of intraventricularly administered oligodeoxynucleotides: implications for therapeutic application within the central nervous system. Proc. Nat. Acad. Sci USA, 90(10): 4665-4669, 1993.
-
(1993)
Proc. Nat. Acad. Sci USA
, vol.90
, Issue.10
, pp. 4665-4669
-
-
Whitesell, L.1
-
10
-
-
0031900833
-
The spread and uptake pattern of intracerebrally administered oligonucleotides in nerve and glial cell populations of the rat brain
-
Sommer, W. et al., The spread and uptake pattern of intracerebrally administered oligonucleotides in nerve and glial cell populations of the rat brain. Antisense Nucleic Acid Drug Dev., 8(2): 75-85, 1998.
-
(1998)
Antisense Nucleic Acid Drug Dev.
, vol.8
, Issue.2
, pp. 75-85
-
-
Sommer, W.1
-
12
-
-
0029833019
-
Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide
-
Yazaki, T. et al., Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide. Mol. Pharmacol., 50(2): 236-242, 1996.
-
(1996)
Mol. Pharmacol.
, vol.50
, Issue.2
, pp. 236-242
-
-
Yazaki, T.1
-
13
-
-
12644302203
-
Pharmacokinetic properties of several novel oligonucleotide analogs in mice
-
Crooke, S.T. et al., Pharmacokinetic properties of several novel oligonucleotide analogs in mice. J. Pharmacol. Exp. Ther., 277(2): 923-937, 1996.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.277
, Issue.2
, pp. 923-937
-
-
Crooke, S.T.1
-
14
-
-
0031763412
-
Drug delivery of antisense molecules to the brain for treatment of Alzheimer’s disease and cerebral AIDS
-
Boado, R.J., Tsukamoto, H., and Pardridge, W.M., Drug delivery of antisense molecules to the brain for treatment of Alzheimer’s disease and cerebral AIDS. J. Pharm. Sci., 87(11): 1308-1315, 1998.
-
(1998)
J. Pharm. Sci.
, vol.87
, Issue.11
, pp. 1308-1315
-
-
Boado, R.J.1
Tsukamoto, H.2
Pardridge, W.M.3
-
15
-
-
85057658379
-
-
Vitravene™ product insert
-
Vitravene™ product insert.
-
-
-
-
16
-
-
0036069080
-
Down-regulation of NOSII gene expression by iontophoresis of anti-sense oligonucleotide in endotoxin-induced uveitis
-
Voigt, M. et al., Down-regulation of NOSII gene expression by iontophoresis of anti-sense oligonucleotide in endotoxin-induced uveitis. Biochem. Biophys. Res. Commun., 295: 336-341, 2002.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.295
, pp. 336-341
-
-
Voigt, M.1
-
17
-
-
0001941928
-
The structure and development of skin
-
Fitzpatrick, T.B., Eigen, A.Z., Wolff, K., Freedberg, I.M., and Austen, K.F., eds., McGraw Hill, New York
-
Holbrook, K.A. and Wolf., K., The structure and development of skin, in Dermatology in General Medicine. Fitzpatrick, T.B., Eigen, A.Z., Wolff, K., Freedberg, I.M., and Austen, K.F., eds., McGraw Hill, New York, 97-145, 1993.
-
(1993)
Dermatology in General Medicine.
, pp. 97-145
-
-
Holbrook, K.A.1
Wolf, K.2
-
19
-
-
20544444237
-
Effect of benzalkonium chloride on percutaneous absorption of antisense phosphorothioate oligonucleotides
-
Lee, Y.M. et al., Effect of benzalkonium chloride on percutaneous absorption of antisense phosphorothioate oligonucleotides. Arch. Phar. Res., 19: 435-440, 1996.
-
(1996)
Arch. Phar. Res.
, vol.19
, pp. 435-440
-
-
Lee, Y.M.1
-
20
-
-
0029125922
-
Ultrasound-mediated transdermal protein delivery
-
Mitragotri, S., Blankschtein, D., and Langer, R., Ultrasound-mediated transdermal protein delivery. Science, 269: 850-853, 1995.
-
(1995)
Science
, vol.269
, pp. 850-853
-
-
Mitragotri, S.1
Blankschtein, D.2
Langer, R.3
-
21
-
-
0031670292
-
Parameters controlling topical delivery of oligonucleotides by electroporation
-
Regnier, V., Le Doan, T., and Preat V., Parameters controlling topical delivery of oligonucleotides by electroporation. J. Drug Target., 5: 275-289, 1998.
-
(1998)
J. Drug Target.
, vol.5
, pp. 275-289
-
-
Regnier, V.1
Le Doan, T.2
Preat, V.3
-
22
-
-
0032440065
-
Assessing the potential of skin electroporation for the delivery of protein-and gene-based drugs
-
Banga, A.K. and Prausnitz, M.R., Assessing the potential of skin electroporation for the delivery of protein-and gene-based drugs. Trends Biotechnol., 16: 408-412, 1998.
-
(1998)
Trends Biotechnol.
, vol.16
, pp. 408-412
-
-
Banga, A.K.1
Prausnitz, M.R.2
-
23
-
-
0001947359
-
Water. The most natural penetration enhancer
-
Hadgraft J., ed., Marcel Dekker, New York
-
Roberts, M.S. and Walker, M., Water. The most natural penetration enhancer, in Pharmaceutical Skin Penetration Enhancers. Hadgraft J., ed., Marcel Dekker, New York, 1995, 1-30.
-
(1995)
Pharmaceutical Skin Penetration Enhancers.
, pp. 1-30
-
-
Roberts, M.S.1
Walker, M.2
-
24
-
-
4244041831
-
Mechanism of skin penetration enhancer: Ethyl acetate
-
Catz, P. and Friend, D.R., Mechanism of skin penetration enhancer: Ethyl acetate. Pharm. Res., 6: 108, 1988.
-
(1988)
Pharm. Res.
, vol.6
, pp. 108
-
-
Catz, P.1
Friend, D.R.2
-
25
-
-
0020047407
-
Mechanisms of sebum production and delivery in man
-
Millns, J.L. and Maibach, H.I., Mechanisms of sebum production and delivery in man. Arch. Dermatol. Res., 272: 351-362, 1982.
-
(1982)
Arch. Dermatol. Res.
, vol.272
, pp. 351-362
-
-
Millns, J.L.1
Maibach, H.I.2
-
26
-
-
0002095226
-
Azone. Mechanism of action and clinical effects
-
J. Hadgraft, ed., Marcel Dekker, New York
-
Hadgraft, J. and Williams, D.G., Azone. Mechanism of action and clinical effects, in Pharmaceutical Skin Penetration Enhancers. J. Hadgraft, ed., Marcel Dekker, New York, 1993, 175-197.
-
(1993)
Pharmaceutical Skin Penetration Enhancers.
, pp. 175-197
-
-
Hadgraft, J.1
Williams, D.G.2
-
27
-
-
0027456749
-
In-vitro evaluation of a series of azone analogs as dermal penetration enhancers
-
Michniak, B., In-vitro evaluation of a series of azone analogs as dermal penetration enhancers. Int. J. Pharm., 91: 85-93, 1993.
-
(1993)
Int. J. Pharm.
, vol.91
, pp. 85-93
-
-
Michniak, B.1
-
28
-
-
0030667690
-
Pharmacokinetics and metabolism in mice of a phosphorothioate oligonucleotide antisense inhibitor of C-RAF-1 kinase expression
-
Geary, R.S. et al., Pharmacokinetics and metabolism in mice of a phosphorothioate oligonucleotide antisense inhibitor of C-RAF-1 kinase expression. Drug Metab. Dispos., 25(11): 1272-1281, 1997.
-
(1997)
Drug Metab. Dispos.
, vol.25
, Issue.11
, pp. 1272-1281
-
-
Geary, R.S.1
-
29
-
-
14944350956
-
Inhaled p38α Mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice
-
Duan, W. et al., Inhaled p38α Mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice. Am. J. Respir. Crit. Care Med., 171(6): 571-578, 2005.
-
(2005)
Am. J. Respir. Crit. Care Med.
, vol.171
, Issue.6
, pp. 571-578
-
-
Duan, W.1
-
30
-
-
0342902407
-
Airway-to-biophase transfer of inhaled oligonucleotides
-
Wu-Pong, S. and Byron, P.R., Airway-to-biophase transfer of inhaled oligonucleotides. Adv. Drug Delivery Rev., 19(1): 47-71, 1996.
-
(1996)
Adv. Drug Delivery Rev.
, vol.19
, Issue.1
, pp. 47-71
-
-
Wu-Pong, S.1
Byron, P.R.2
-
31
-
-
85057654411
-
-
unpublished results
-
Deshmukh, H., unpublished results, 2002.
-
(2002)
-
-
Deshmukh, H.1
-
32
-
-
0031454495
-
Pulmonary drug delivery: Physiologic and mechanistic aspects
-
Yu, J. and Chien, Y.W., Pulmonary drug delivery: physiologic and mechanistic aspects. Crit. Rev. Ther. Drug Carrier Syst., 14(4): 395-453, 1997.
-
(1997)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.14
, Issue.4
, pp. 395-453
-
-
Yu, J.1
Chien, Y.W.2
-
33
-
-
0032751968
-
Distribution of a 20-mer phosphorothioate oligonucleotide, CGP69846A (ISIS 5132), into airway leukocytes and epithelial cells following intratracheal delivery to Brown-Norway rats
-
Danahay, H. et al., Distribution of a 20-mer phosphorothioate oligonucleotide, CGP69846A (ISIS 5132), into airway leukocytes and epithelial cells following intratracheal delivery to Brown-Norway rats. Pharm. Res., 16(10): 1542-1549, 1999.
-
(1999)
Pharm. Res.
, vol.16
, Issue.10
, pp. 1542-1549
-
-
Danahay, H.1
-
34
-
-
0033763150
-
Pharmacokinetic and toxicity profile of a phosphorothioate oligodeoxynucleotide following inhalation delivery to lung in mice
-
Templin, M.V. et al., Pharmacokinetic and toxicity profile of a phosphorothioate oligodeoxynucleotide following inhalation delivery to lung in mice. Antisense Nucleic Acid Drug Dev., 10: 359-368, 2000.
-
(2000)
Antisense Nucleic Acid Drug Dev.
, vol.10
, pp. 359-368
-
-
Templin, M.V.1
-
35
-
-
85057672890
-
-
unpublished observations
-
Hung, E., unpublished observations, 2005.
-
(2005)
-
-
Hung, E.1
-
36
-
-
0031025249
-
DNA antisense therapy for asthma in an animal model
-
(London)
-
Nyce, J.W. and Metzger, W.J., DNA antisense therapy for asthma in an animal model. Nature (London), 385(6618): 721-725, 1997.
-
(1997)
Nature
, vol.385
, Issue.6618
, pp. 721-725
-
-
Nyce, J.W.1
Metzger, W.J.2
-
37
-
-
0030850579
-
Respirable antisense oligonucleotides as novel therapeutic agents for asthma and other pulmonary diseases
-
Nyce, J.W., Respirable antisense oligonucleotides as novel therapeutic agents for asthma and other pulmonary diseases. Expert Opin. Invest. Drugs, 6(9): 1149-1156, 1997.
-
(1997)
Expert Opin. Invest. Drugs
, vol.6
, Issue.9
, pp. 1149-1156
-
-
Nyce, J.W.1
-
38
-
-
85057697627
-
Inhaled antisense oligonucleotide therapies: Inspiration and progress
-
in press
-
Karras, J.G., Geary, R.S., and Gregory, S.A., Inhaled antisense oligonucleotide therapies: inspiration and progress. Drug Discov. Today, in press.
-
Drug Discov. Today
-
-
Karras, J.G.1
Geary, R.S.2
Gregory, S.A.3
-
39
-
-
0002604431
-
The oral bioavailability of peptides and related drugs
-
Davis, S.S., Illum, L., and Tomlinson, E., eds., Plenum Press, New York
-
Humphrey, M.J., The oral bioavailability of peptides and related drugs, in Delivery Systems for Peptide Drugs. Davis, S.S., Illum, L., and Tomlinson, E., eds., Plenum Press, New York, pp. 139-151, 1986.
-
(1986)
Delivery Systems for Peptide Drugs.
, pp. 139-151
-
-
Humphrey, M.J.1
-
40
-
-
0000397940
-
Pharmacokinetics and bioavailability of antisense oligonucleotides following oral and colorectal administrations in experimental animals
-
Antisense Research and Application
-
Agrawal, S. and Zhang, R., Pharmacokinetics and bioavailability of antisense oligonucleotides following oral and colorectal administrations in experimental animals. Handb. Exp. Pharmacol., 131 (Antisense Research and Application): 525-543, 1998.
-
(1998)
Handb. Exp. Pharmacol.
, vol.131
, pp. 525-543
-
-
Agrawal, S.1
Zhang, R.2
-
41
-
-
0000433389
-
Pharmacokinetic properties of phosphorothioates in animals-absorption, distribution, metabolism and elimination
-
Antisense Research and Application
-
Nicklin, P.L., Craig, S.J., and Phillips, J.A., Pharmacokinetic properties of phosphorothioates in animals-absorption, distribution, metabolism and elimination. Handb. Exp. Pharmacol., 131(Antisense Research and Application): 141-168, 1998.
-
(1998)
Handb. Exp. Pharmacol.
, vol.131
, pp. 141-168
-
-
Nicklin, P.L.1
Craig, S.J.2
Phillips, J.A.3
-
42
-
-
0029134526
-
In vivo stability, disposition and metabolism of a “hybrid” oligonucleotide phosphorothioate in rats
-
Zhang, R. et al., In vivo stability, disposition and metabolism of a “hybrid” oligonucleotide phosphorothioate in rats. Biochem. Pharmacol., 50(4): 545-556, 1995.
-
(1995)
Biochem. Pharmacol.
, vol.50
, Issue.4
, pp. 545-556
-
-
Zhang, R.1
-
43
-
-
0030426849
-
Pharmacokinetics and tissue disposition of a chimeric oligodeoxynucleotides phosphorothioate in rats after intravenous administration
-
Zhang, R. et al., Pharmacokinetics and tissue disposition of a chimeric oligodeoxynucleotides phosphorothioate in rats after intravenous administration. J. Pharmacol. Exp. Ther., 278(2): 971-979, 1996.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.278
, Issue.2
, pp. 971-979
-
-
Zhang, R.1
-
44
-
-
18844455464
-
Second generation of antisense oligonucleotides. From nuclease resistance to biological efficacy in animals
-
Altmann, K.-H. et al., Second generation of antisense oligonucleotides. From nuclease resistance to biological efficacy in animals. Chimia, 50(4): 168-176, 1996.
-
(1996)
Chimia
, vol.50
, Issue.4
, pp. 168-176
-
-
Altmann, K.-H.1
-
45
-
-
17144374243
-
Antisense oligonucleotide-based therapeutics
-
Templeton, N.S., ed., Marcel Dekker, New York
-
Bennett, C.F. et al., Antisense oligonucleotide-based therapeutics, in Gene and Cell Therapy:Therapeutic Mechanisms and Strategies. Templeton, N.S., ed., Marcel Dekker, New York, pp. 347-374, 2004.
-
(2004)
Gene and Cell Therapy:Therapeutic Mechanisms and Strategies.
, pp. 347-374
-
-
Bennett, C.F.1
-
47
-
-
0032990267
-
Potential of low molecular mass chitosan as a DNA delivery system: Biocompatibility, body distribution and ability to complex and protect DNA
-
Richardson, S.C.W., Kolbe, H.V.J., and Duncan, R., Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA. Int. J. Pharm., 178(2): 231-243, 1999.
-
(1999)
Int. J. Pharm.
, vol.178
, Issue.2
, pp. 231-243
-
-
Richardson, S.C.W.1
Kolbe, H.V.J.2
Duncan, R.3
-
48
-
-
0033029944
-
Evaluation of aminoalkylmethacrylate nanoparticles as colloidal drug carrier systems. Part 2. Characterization of antisense oligonucleotides loaded copolymer nanoparticles
-
Zobel, H.P. et al., Evaluation of aminoalkylmethacrylate nanoparticles as colloidal drug carrier systems. Part 2. Characterization of antisense oligonucleotides loaded copolymer nanoparticles. Eur. J. Pharm. Biopharm., 48(1): 1-12, 1999.
-
(1999)
Eur. J. Pharm. Biopharm.
, vol.48
, Issue.1
, pp. 1-12
-
-
Zobel, H.P.1
-
49
-
-
0034060189
-
Absorption of antisense oligonucleotides in rat intestine: Effect of chemistry and length
-
Khatsenko, O. et al., Absorption of antisense oligonucleotides in rat intestine: effect of chemistry and length. Antisense Nucleic Acid Drug Dev, 10(1): 35-44, 2000.
-
(2000)
Antisense Nucleic Acid Drug Dev
, vol.10
, Issue.1
, pp. 35-44
-
-
Khatsenko, O.1
-
50
-
-
0027174290
-
Sodium caprate elicits dilatations in human intestinal tight junctions and enhances drug absorption by the paracellular route
-
Anderberg, E.K., Lindmark, T., and Artursson, P., Sodium caprate elicits dilatations in human intestinal tight junctions and enhances drug absorption by the paracellular route. Pharm. Res., 10(6):857-864, 1993.
-
(1993)
Pharm. Res.
, vol.10
, Issue.6
, pp. 857-864
-
-
Anderberg, E.K.1
Lindmark, T.2
Artursson, P.3
-
51
-
-
0029859233
-
The relationship between rat intestinal permeability and hydrophilic probe size
-
Lane, M.E., O’Driscoll, C.M., and Corrigan, O.I., The relationship between rat intestinal permeability and hydrophilic probe size. Pharm. Res., 13(10): 1554-1558, 1996.
-
(1996)
Pharm. Res.
, vol.13
, Issue.10
, pp. 1554-1558
-
-
Lane, M.E.1
O’Driscoll, C.M.2
Corrigan, O.I.3
-
52
-
-
0031874206
-
Reversible increase in tight junction permeability to macromolecules in rat ileal mucosa in vitro by sodium caprate, a constituent of milk fat
-
Soderholm, J.D. et al., Reversible increase in tight junction permeability to macromolecules in rat ileal mucosa in vitro by sodium caprate, a constituent of milk fat. Dig. Dis. Sci., 43(7): 1547-1552, 1998.
-
(1998)
Dig. Dis. Sci.
, vol.43
, Issue.7
, pp. 1547-1552
-
-
Soderholm, J.D.1
-
53
-
-
85057685837
-
-
unpublished results
-
Teng, C.-L., unpublished results, 1998.
-
(1998)
-
-
Teng, C.-L.1
-
54
-
-
0026329336
-
Mucosal penetration enhancers of facilitation of peptide and protein drug absorption
-
Lee, V.H., Yamamoto, A., and Kompella, U.B., Mucosal penetration enhancers of facilitation of peptide and protein drug absorption. Crit. Rev. Ther. Drug Carrier Syst., 8(2): 91-192, 1991.
-
(1991)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.8
, Issue.2
, pp. 91-192
-
-
Lee, V.H.1
Yamamoto, A.2
Kompella, U.B.3
-
55
-
-
0026630075
-
The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn’s disease
-
Hollander, D., The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn’s disease. Scand. J. Gastro., 27: 721-726, 1992.
-
(1992)
Scand. J. Gastro.
, vol.27
, pp. 721-726
-
-
Hollander, D.1
-
56
-
-
85057664545
-
-
unpublished results
-
Geary, R.S., unpublished results, 2004.
-
(2004)
-
-
Geary, R.S.1
-
57
-
-
85057687876
-
Oral delivery of antisense oligonucleotides: Plasma bioavailability of ISIS 104838 in man. Accepted for publication
-
Tillman, L.G., Geary, R.S., and Hardee, G.E., Oral delivery of antisense oligonucleotides: plasma bioavailability of ISIS 104838 in man. Accepted for publication, J. Pharm. Sci., 2007.
-
(2007)
J. Pharm. Sci.
-
-
Tillman, L.G.1
Geary, R.S.2
Hardee, G.E.3
-
59
-
-
0029836444
-
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
-
(NY)
-
Neurath, M.F. et al., Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice. Nat. Med. (NY), 2(9): 998-1004, 1996.
-
(1996)
Nat. Med.
, vol.2
, Issue.9
, pp. 998-1004
-
-
Neurath, M.F.1
-
60
-
-
85057672531
-
Down-regulation of gene expression by colorectal administration of synthetic oligonucleotides
-
WO 9840058
-
Zhang, R. and Agrawal, S., Down-regulation of gene expression by colorectal administration of synthetic oligonucleotides, PCT Int. Appl., WO 9840058, 1998.
-
(1998)
PCT Int. Appl.
-
-
Zhang, R.1
Agrawal, S.2
|