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Volumn 10, Issue 1, 2000, Pages 35-44

Absorption of antisense oligonucleotides in rat intestine: Effect of chemistry and length

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYTOSINE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; OLIGORIBONUCLEOTIDE;

EID: 0034060189     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.2000.10.35     Document Type: Article
Times cited : (55)

References (35)
  • 1
    • 0031278019 scopus 로고    scopus 로고
    • Perspectives in antisense therapeutics
    • AGRAWAL, S., and IYER, R.P. (1997). Perspectives in antisense therapeutics. Pharmacol. Ther. 76, 151-160.
    • (1997) Pharmacol. Ther. , vol.76 , pp. 151-160
    • Agrawal, S.1    Iyer, R.P.2
  • 2
    • 0000397940 scopus 로고    scopus 로고
    • Pharmacokinetics and bioavailability of antisense oligonucleotides following oral and colorectal administrations in experimental animals
    • "Antisense Research and Application." S.T. Crooke, ed. (Springer-Verlag, Berlin, Heidelberg)
    • AGRAWAL, S., and ZHANG, R. (1998). Pharmacokinetics and bioavailability of antisense oligonucleotides following oral and colorectal administrations in experimental animals. In: Handbook of Experimental Pharmacology, "Antisense Research and Application." S.T. Crooke, ed. (Springer-Verlag, Berlin, Heidelberg), vol. 131, 525-543.
    • (1998) Handbook of Experimental Pharmacology , vol.131 , pp. 525-543
    • Agrawal, S.1    Zhang, R.2
  • 4
    • 0027981853 scopus 로고
    • Efficient synthesis of antisense oligodeoxyribonucleotide phosphorothioates
    • ANDRADE, M., SCOZZARI, A., COLE, D.L., and RAVIJUMAR, V.T. (1994). Efficient synthesis of antisense oligodeoxyribonucleotide phosphorothioates. Bioorg. Med. Chem. Lett. 4, 2017-2022.
    • (1994) Bioorg. Med. Chem. Lett. , vol.4 , pp. 2017-2022
    • Andrade, M.1    Scozzari, A.2    Cole, D.L.3    Ravijumar, V.T.4
  • 5
    • 0031889133 scopus 로고    scopus 로고
    • Effects of size and sequence on the iontophoretic delivery of oligonucleotides
    • BRAND, R.M., WAHL, A., and IVERSEN, P.L. (1997). Effects of size and sequence on the iontophoretic delivery of oligonucleotides. J. Pharm. Sci. 87, 49-52.
    • (1997) J. Pharm. Sci. , vol.87 , pp. 49-52
    • Brand, R.M.1    Wahl, A.2    Iversen, P.L.3
  • 7
    • 0029077840 scopus 로고
    • Characterization of fully 2′-modified oligoribonucleotide hetero- And homoduplex hybridization and nuclease sensitivity
    • CUMMINS, L.L., OWENS, S.R., RISEN, L.M., LESNIK, E.A., FREIER, S.M., McGEE, D., GUINOSSO, C.J., and COOK, P.D. (1995). Characterization of fully 2′-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity. Nucleic Acids Res. 23, 2019-2024.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2019-2024
    • Cummins, L.L.1    Owens, S.R.2    Risen, L.M.3    Lesnik, E.A.4    Freier, S.M.5    McGee, D.6    Guinosso, C.J.7    Cook, P.D.8
  • 8
    • 0030839546 scopus 로고    scopus 로고
    • Identification and characterization of second-generation antisense oligonucleotides
    • DEAN, N.M., and GRIFFEY, R.H. (1997). Identification and characterization of second-generation antisense oligonucleotides. Antisense Nucleic Acid Drug Dev. 7, 229-233.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 229-233
    • Dean, N.M.1    Griffey, R.H.2
  • 9
    • 0014589701 scopus 로고
    • Drug absorption. I. An in situ rat gut technique yielding realistic absorption rates
    • DOLUISIO, J.T., BILLUPS, N.F., DITTERT, L.W., SUGITA, E.T., and SWINTOSKY, J.V. (1969). Drug absorption. I. An in situ rat gut technique yielding realistic absorption rates. J. Pharm. Sci. 58, 1196-1200.
    • (1969) J. Pharm. Sci. , vol.58 , pp. 1196-1200
    • Doluisio, J.T.1    Billups, N.F.2    Dittert, L.W.3    Sugita, E.T.4    Swintosky, J.V.5
  • 10
  • 11
    • 0030667690 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism in mice of a phosphorothioate oligonucleotide antisense inhibitor of C-raf-1 kinase expression
    • GEARY, R.S. LEEDS, J.M., FITCHETT, J., BURCKIN, T., TROUNG, L., SPAINHOUR, C., CREEK, M., and LEVIN, A.A. (1997a). Pharmacokinetics and metabolism in mice of a phosphorothioate oligonucleotide antisense inhibitor of C-raf-1 kinase expression. Drug Metab. Dispos. 25, 1272-1281.
    • (1997) Drug Metab. Dispos. , vol.25 , pp. 1272-1281
    • Geary, R.S.1    Leeds, J.M.2    Fitchett, J.3    Burckin, T.4    Troung, L.5    Spainhour, C.6    Creek, M.7    Levin, A.A.8
  • 12
    • 0030797704 scopus 로고    scopus 로고
    • Antisense oligonucleotide inhibitors for the treatment of cancer: 1. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides
    • GEARY, R.S., LEEDS, J.M., HENRY, S.P., MONTEITH, D.M., and LEVIN, A.A. (1997b). Antisense oligonucleotide inhibitors for the treatment of cancer: 1. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides. Anti-Cancer Drug Design 12, 383-394.
    • (1997) Anti-Cancer Drug Design , vol.12 , pp. 383-394
    • Geary, R.S.1    Leeds, J.M.2    Henry, S.P.3    Monteith, D.M.4    Levin, A.A.5
  • 15
    • 0030797705 scopus 로고    scopus 로고
    • Toxicological and pharmacokinetic properties of chemically modified antisense oligonucleotide inhibitors of PKC-alpha and C-raf kinase
    • HENRY, S.P., MONTEITH, D., BENNETT, C.F., and LEVIN, A.A. (1997). Toxicological and pharmacokinetic properties of chemically modified antisense oligonucleotide inhibitors of PKC-alpha and C-raf kinase. Anti-Cancer Drug Design 12, 409-420.
    • (1997) Anti-Cancer Drug Design , vol.12 , pp. 409-420
    • Henry, S.P.1    Monteith, D.2    Bennett, C.F.3    Levin, A.A.4
  • 16
    • 0030984740 scopus 로고    scopus 로고
    • Simultaneous analysis of several non-steroidal anti-inflammatory drugs in human urine by high-performance liquid chromatography with normal solid-phase extraction
    • MIRAI, T., MATSUMOTO, S., and KISHI, I. (1997). Simultaneous analysis of several non-steroidal anti-inflammatory drugs in human urine by high-performance liquid chromatography with normal solid-phase extraction. J. Chromatogr. Biomed. Sci. Appl. 692, 375-388.
    • (1997) J. Chromatogr. Biomed. Sci. Appl. , vol.692 , pp. 375-388
    • Mirai, T.1    Matsumoto, S.2    Kishi, I.3
  • 18
    • 0026919380 scopus 로고
    • Binding of antisense phosphorothioate oligonucleotides to murine lymphocytes is lineage specific and inducible
    • IVERSEN, P.L., CROUSE, D., ZON, G., and PERRY, G. (1992). Binding of antisense phosphorothioate oligonucleotides to murine lymphocytes is lineage specific and inducible. Antisense Res. Dev. 2, 223-233.
    • (1992) Antisense Res. Dev. , vol.2 , pp. 223-233
    • Iversen, P.L.1    Crouse, D.2    Zon, G.3    Perry, G.4
  • 19
    • 0018850819 scopus 로고
    • Quantitative mechanistic studies in simultaneous fluid flow and intestinal absorption using steroids as model solutes
    • KOMIYA, J., PARK, A., KAMANI, A., HO, N.F.H., and HIGUCHI, W.J. (1980). Quantitative mechanistic studies in simultaneous fluid flow and intestinal absorption using steroids as model solutes. Int. J. Pharm. 4, 249-262.
    • (1980) Int. J. Pharm. , vol.4 , pp. 249-262
    • Komiya, J.1    Park, A.2    Kamani, A.3    Ho, N.F.H.4    Higuchi, W.J.5
  • 20
    • 0029859233 scopus 로고    scopus 로고
    • The relationship between rat intestinal permeability and hydrophilic probe size
    • LANE, M.E., O'DRISCOLL, C.M., and CORRIGAN, O.I. (1996). The relationship between rat intestinal permeability and hydrophilic probe size. Pharm. Res. 13, 1554-1558.
    • (1996) Pharm. Res. , vol.13 , pp. 1554-1558
    • Lane, M.E.1    O'Driscoll, C.M.2    Corrigan, O.I.3
  • 21
    • 0030065059 scopus 로고    scopus 로고
    • Quantitation of phosphorothioate oligonucleotides in human plasma
    • LEEDS, J.M., GRAHAM, M.J., TROUNG, L., and CUMMINS, L.L. (1996). Quantitation of phosphorothioate oligonucleotides in human plasma. Anal. Biochem. 235, 36-43.
    • (1996) Anal. Biochem. , vol.235 , pp. 36-43
    • Leeds, J.M.1    Graham, M.J.2    Troung, L.3    Cummins, L.L.4
  • 22
    • 0030874388 scopus 로고    scopus 로고
    • Pharmacokinetics of a potential human cytomegalovirus therapeutic, a phosphorothioate oligonucleotide, after intravitreal injections in the rabbit
    • LEEDS, J.M., HENRY, S.P., TRUONG, L., ZUTSI, A., LEVIN, A.A., and KORNBRUST, D.J. (1997). Pharmacokinetics of a potential human cytomegalovirus therapeutic, a phosphorothioate oligonucleotide, after intravitreal injections in the rabbit. Drug Metab. Dispos. 25, 921-926.
    • (1997) Drug Metab. Dispos. , vol.25 , pp. 921-926
    • Leeds, J.M.1    Henry, S.P.2    Truong, L.3    Zutsi, A.4    Levin, A.A.5    Kornbrust, D.J.6
  • 25
    • 0028598284 scopus 로고
    • Study of antisense oligonucleotide phosphorothioates containing segments of oligodeoxynucleotides and 2′-O-methyloligoribonucleotides
    • METELEV, V., LISZIEWWICZ, J., and AGRAWAL, S. (1994). Study of antisense oligonucleotide phosphorothioates containing segments of oligodeoxynucleotides and 2′-O-methyloligoribonucleotides. Bioorg. Med. Chem. 4, 2929-2934.
    • (1994) Bioorg. Med. Chem. , vol.4 , pp. 2929-2934
    • Metelev, V.1    Lisziewwicz, J.2    Agrawal, S.3
  • 27
    • 0031950147 scopus 로고    scopus 로고
    • Pulmonary bioavailability of a phosphorothioate oligonucleotide (CGP 64128A): Comparison with other delivery routes
    • NICKLIN, P.L., BAYLEY, D., GIDDINGS, J., CRAIG, S.J., CUMMINS, L.L., HASTEWELL, J.G., and PHILLIPS, J.A. (1998). Pulmonary bioavailability of a phosphorothioate oligonucleotide (CGP 64128A): Comparison with other delivery routes. Pharm. Res. 15, 583-591.
    • (1998) Pharm. Res. , vol.15 , pp. 583-591
    • Nicklin, P.L.1    Bayley, D.2    Giddings, J.3    Craig, S.J.4    Cummins, L.L.5    Hastewell, J.G.6    Phillips, J.A.7
  • 28
    • 0029142539 scopus 로고
    • Iontophoretic delivery of oligonucleotides across full thickness hairless mouse skin
    • OLDENBURG, K.R., VO, K.T., SMITH, G.A., and SELICK, H.E. (1995). Iontophoretic delivery of oligonucleotides across full thickness hairless mouse skin. J. Pharm. Sci. 84, 915-921.
    • (1995) J. Pharm. Sci. , vol.84 , pp. 915-921
    • Oldenburg, K.R.1    Vo, K.T.2    Smith, G.A.3    Selick, H.E.4
  • 32
    • 0001929474 scopus 로고    scopus 로고
    • Shutting down a gene. Antisense drug wins approval
    • STIX, G. (1998). Shutting down a gene. Antisense drug wins approval. Sci. Am. 279, 46-50.
    • (1998) Sci. Am. , vol.279 , pp. 46-50
    • Stix, G.1
  • 33
    • 0025147202 scopus 로고
    • Absorption rate of drugs in rats. Application of the improved modified Doluisio method to various classes of drugs
    • VONDERSCHER, J., BURI, P., DESHUSSES, J., and SUCKER, H. (1990). Absorption rate of drugs in rats. Application of the improved modified Doluisio method to various classes of drugs. Acta Pharm. Technol. 36, 133-138.
    • (1990) Acta Pharm. Technol. , vol.36 , pp. 133-138
    • Vonderscher, J.1    Buri, P.2    Deshusses, J.3    Sucker, H.4
  • 35
    • 0029002066 scopus 로고
    • In vivo stability and disposition of a self-stabilized oligodeoxynucleotide phosphorothioate in rats
    • ZHANG, R., LU, Z., ZHANG, X., ZHAO, H., DIASIO, R.B., LIU, T., JIANG, Z., and AGRAWAL, S. (1995). In vivo stability and disposition of a self-stabilized oligodeoxynucleotide phosphorothioate in rats. Clin. Chem. 41, 836-843.
    • (1995) Clin. Chem. , vol.41 , pp. 836-843
    • Zhang, R.1    Lu, Z.2    Zhang, X.3    Zhao, H.4    Diasio, R.B.5    Liu, T.6    Jiang, Z.7    Agrawal, S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.