p,p′-methoxyl-diphenyl diselenide prevents neurodegeneration and glial cell activation induced by streptozotocin in rats

Journal of Alzheimer's Disease

Volumn 33, Issue 1, 2013, Pages 133-144

  Pinton, Simone ^a   Sampaio, Tuane Bazanella ^a   Ramalho, Rita M ^b   Rodrigues, Cecília M P ^b   Nogueira, Cristina Wayne ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

Author keywords

Apoptosis; glial cells; memory; neuroinflammation; organoselenium compounds; streptozotocin

Indexed keywords

CASPASE 3; DIPHENYL DISELENIDE; GLIAL FIBRILLARY ACIDIC PROTEIN; P,P' METHOXYL DIPHENYL DISELENIDE; STREPTOZOCIN; UNCLASSIFIED DRUG; BENZENE DERIVATIVE; NEUROPROTECTIVE AGENT; ORGANOSELENIUM DERIVATIVE; P METHOXY DIPHENYL DISELENIDE; P-METHOXY-DIPHENYL DISELENIDE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; CELL ACTIVATION; CONTROLLED STUDY; DENDRITE; DIET SUPPLEMENTATION; GLIA CELL; HIPPOCAMPUS; IMMUNOFLUORESCENCE; MALE; MEMORY DISORDER; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; RAT; SYNAPSE; ANIMAL; CHEMICALLY INDUCED DISORDER; DEGENERATIVE DISEASE; DRUG EFFECT; EXPLORATORY BEHAVIOR; GLIA; MEMORY; METABOLISM; PATHOLOGY; PHYSIOLOGY; WISTAR RAT;

ANIMALS; BENZENE DERIVATIVES; EXPLORATORY BEHAVIOR; MALE; MEMORY; NEURODEGENERATIVE DISEASES; NEUROGLIA; NEUROPROTECTIVE AGENTS; ORGANOSELENIUM COMPOUNDS; RATS; RATS, WISTAR; STREPTOZOCIN;

EID: 84872464751     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-121150     Document Type: Article

References (43)

1. Dua T, Cumbrera MG, Mathers C, Saxena S (2006) Neurological Disorders: Public Health Challenges, Aarli JA, Avanzini G, Bertolote JM, Boer H, Breivik H, Dua T, Graham N, Janca A, Kesselring J, Mathers C, Muscetta A, Prilipko L, Saraceno B, Saxena S, Steiner TJ, eds.WHO,Switzerland, pp. 281-304.
2. Selkoe DJ (2011) Resolving controversies on the path to Alzheimer's therapeutics. Nat Med 17, 1060-1065.
3. Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 297, 353-356. (Pubitemid 34790756)
4. Parihar MS, Brewer GJ (2010) Mamyloid-beta as a modulator of synaptic plasticity. J Alzheimers Dis 22, 741-763.
5. Xiong S, Markesbery WR, Shao C, Lovell MA (2007) Seleno-L-methionine protects against beta-amyloid and iron/hydrogen peroxide-mediated neuron death. Antioxid Redox Signal 9, 457-467.
6. Loef M, Schrauzer GN, Walach H (2011) Selenium and Alzheimer's disease: A systematic review. J Alzheimers Dis 26, 81-104.
7. Savarino L, Granchi D, Ciapetti G, Cenni E, Ravaglia G, Forti P, Maioli F, Mattioli R (2001) Serum concentrations of zinc and selenium in elderly people: Results in healthy nonagenarians/centenarians. Exp Gerontol 36, 327-339. (Pubitemid 32164435)
8. Vural H, Demirin H, Kara Y, Eren I, Delibas N (2010) Alterations of plasma magnesium, copper, zinc, iron and selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with Alzheimer's disease. J Trace Elem Med Biol 23, 169-173.
9. Ishrat T, Parveen K, Khan MM, Khuwaja G, Khan MB, Yousuf S, Ahmad A, Shrivastav P, Islam F (2009) Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type. Brain Res 1281, 117-127.
10. Lovell MA, Xiong S, Lyubartseva G, Markesbery WR (2009) Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice. Free Radic Biol Med 46, 1527-1533.
11. Gwon AR, Park JS, Park JH, Baik SH, Jeong HY, Hyun DH, Park KW, Jo DG (2010) Selenium attenuates A production and A-induced neuronal death. Neurosci Lett 469, 391-395.
12. Corcoran NM, Martin D, Hutter-Paier B, Windisch M, Nguyen T, Nheu L, Sundstrom LE, Costello AJ, Hovens CM (2010) Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer's disease model. J Clinical Neurosci 17, 1025-1033.
13. Souza AC, Br?uning CA, Leite MR, Zeni G, Nogueira CW (2010) Diphenyl diselenide improves scopolamine-induced memory impairment in mice. Behav Pharmacol 21, 556-562.
14. Rosa RM, Flores DG, Appelt HR, Braga AL, Henriques JAP, Roesler R (2003) Facilitation of long-term object recognition memory by pretraining administration of diphenyl diselenide in mice. Neurosci Lett 341, 217-220. (Pubitemid 36403767)
15. Stangherlin EC, Luchese C, Pinton S, Rocha JBT, Nogueira CW (2008) Subchronical exposure to diphenyl diselenide enhances acquisition and retention of spatial memory in rats. Brain Res 1201, 106-113.
16. Pinton S, da Rocha JT, Zeni G, Nogueira CW (2010) Organoselenium improves memory decline in mice: Involvement of acetylcholinesterase activity. Neurosci Lett 472, 56-60.
17. Pinton S, da Rocha JT, Gai BM, Prigol M, da Rosa LV, NogueiraCW(2011) Neuroprotector effect of p,p-methoxyldiphenyl diselenide in a model of sporadic dementia of Alzheimer's type in mice: Contribution of antioxidant mechanism. Cell Biochem Funct 29, 235-243.
18. Pinton S, Br?uning CA, Oliveira CES, Prigol M, NogueiraCW (2012) Therapeutic effect of organoselenium dietary supplementation in a sporadic dementia of Alzheimer's type model in rats. J Nutr Biochem, doi:10.1016/j. jnutbio.2012.06.012.
19. Lannert H, Hoyer S (1998) Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats. Behav Neurosci 112, 1199-1208. (Pubitemid 28519002)
20. Paxinos G, Watson C (1986) The Rat Brain in Stereotaxic Coordinates. Academic Press, Sydney.
21. Paulmier C (1986) Selenium Reagents and Intermediates. Organic Synthesis, Pergamon, Oxford.
22. De Bem AF, Portella RF, Colpo E, Duarte MMMF, Frediane A, Taube PS, Nogueira CW, Farina M, Silva EL, Rocha JBT (2009) Diphenyl diselenide decreases serum levels of total cholesterol and tissue oxidative stress in cholesterol-fed rabbits. Basic Clin Pharmacol Toxicol 105, 17-23.
23. Sakaguchi M, Koseki M, Wakamatsu M, Matsumura E (2006) Effects of systemic administration of -casomorphin-5 on learning and memory in mice. Eur J Pharmacol 530, 81-87. (Pubitemid 43037127)
24. Moore AH, O'Banion MK (2002) Neuroinflammation and anti-inflammatory therapy for Alzheimer's disease. Adv Drug Deliv Rev 54, 1627-1656. (Pubitemid 35350856)
25. Hensley K (2010) Neuroinflammation in Alzheimer's disease: Mechanism, pathologic consequences, and potential for therapeutic manipulation. J Alzheimers Dis 21, 1-14.
26. da Rocha JT, Pinton S, Mazzanti A, Mazzanti CM, Beckemann DV, Nogueira CW, Zeni G (2012) Diphenyl diselenide ameliorates cognitive deficits induced by a model of menopause in rats. Behav Pharmacol 23, 98-104.
27. Agrawal R, Tyagi E, Shukla R, Nath C (2009) A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICVSTZinduced dementia. Neuropharmacology 56, 779-787.
28. Sharma N, Deshmukh R, Bedi KL (2010) SP600125, a competitive inhibitor of JNK attenuates streptozotocin induced neurocognitive deficit and oxidative stress in rats. Pharmacol Biochem Behav 96, 386-394.
29. Javed H, Khan MM, Khan A, Vaibhav K, Ahmad A, Khuwaja G, Ahmed ME, Raza SS, Ashafag M, Tabassum R, Siddiqui MS, El-Agnaf OM, Safhi MM, Islam F (2011) S-allylcysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mause model of streptozotocininduced experimental dementia of Alzheimer's type. Brain Res 1389, 133-142.
30. Gouras GK, Tampellini D, Takahashi RH, Capetillo-Zarate E (2010) Intraneural beta-amyloid accumulation and synapse pathology in Alzheimer's disease. Acta Neuropathol 119, 523-541.
31. Castro RE, Santos MM, Gloria PM, Ribeiro CJ, Ferreira DM, Xavier JM, Moreira R, Rodrigues CM (2010) Cell death targets and potential modulation in Alzheimer's disease. Curr Pharm Des 16, 2851-2864.
32. Glass CK, Saijo K,Winner B, MarchettoMC,GageFH(2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140, 918-934.
33. Patten DA, Germain M, Kelly MA, Slack RS (2010) Reactive oxygen species: Stuck in the middle of degeneration. J Alzheimers Dis 20, 357-367.
34. Kundurovic Z, Hasanagic S, Bilalovic N, Gavrankapetanovic E, Alicelebic S (2009) Pro-apoptotic protein Bax and antiapoptotic protein Bcl-2 expression in streptozotocin model of Alzheimer's disease. Healthmed 3, 520-528.
35. Saxena G, Patro IK, Nath C (2011) ICV STZ induced impairment in memory and neuronal mitochondrial function: A protective role of nicotinic receptor. Behav Brain Res 224, 50-57.
36. Rohn TT (2010) The role of caspases in Alzheimer's disease; potential novel therapeutic opportunities. Apoptosis 15, 1403-1409.
37. Steiner B,Wolf S,KempermannG(2006) Adult neurogenesis and neurodegenerative disease. Regen Med 1, 15-28.
38. Chohan MO, Bin L, Blanchard J, Tung YC, Heaney AT, Rabe A, Iqbal K, Igbal IG (2011) Enhancement of dentate gyrus neurogenesis, dendritic and synaptic plasticity and memory by a neurotrophic peptide. Neurobiol Aging 32, 1420-1434.
39. Herman AH, Khandelwal PJ, Rebeck GW, Moussa CEH (2012) Wild type TCP-43 induces neuro-inflammation and alters APP metabolism in lentiviral gene transfer models. Exp Neurol 235, 297-305.
40. Prickaerts J, Fahrig T, Blokland A (1999) Cognitive performance and biochemical markers in septum, hippocampus and striatum of rats after an i.c.v. injection of streptozotocin: A correlation analysis. Behav Brain Res 102, 73-88. (Pubitemid 29314570)
41. Weinstock M, Shoham S (2004) Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity. J Neural Transm 111, 347-366. (Pubitemid 38316610)
42. Rodrigues L, DutraMF, Ilha J, Biasibetti R, Quincozes-Santos A, Leite MC,Marcuzzo S, AchavalM, Gonçalves CA (2010) Treadmill training restores spatial cognitive deficits and neurochemical alterations in the hippocampus of rats submitted to an intracerebroventricular administration of streptozotocin. J Neural Transm 117, 1295-1305.
43. Javed H, Khan MM, Ahmad A, Vaibhav K, Ahmed ME, Khan A, Ashafaq M, Islam F, Siddiqui MS, Safhi MM, Islam F (2012) Rutin prevents cognitive impairment by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type. Neuroscience 210, 340-352.