-
1
-
-
16944366150
-
Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury
-
Grill R., Murai K., Blesch A., Gage F.H., Tuszynski M.H. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J Neurosci 1997, 17:5560-5572.
-
(1997)
J Neurosci
, vol.17
, pp. 5560-5572
-
-
Grill, R.1
Murai, K.2
Blesch, A.3
Gage, F.H.4
Tuszynski, M.H.5
-
2
-
-
18444381777
-
GDNF delivery using human neural progenitor cells in a rat model of ALS
-
Klein S.M., Behrstock S., McHugh J., Hoffmann K., Wallace K., Suzuki M., et al. GDNF delivery using human neural progenitor cells in a rat model of ALS. Hum Gene Ther 2005, 16:509-521.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 509-521
-
-
Klein, S.M.1
Behrstock, S.2
McHugh, J.3
Hoffmann, K.4
Wallace, K.5
Suzuki, M.6
-
3
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
-
Kordower J.H., Emborg M.E., Bloch J., Ma S.Y., Chu Y.P., Leventhal L., et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 2000, 290:767-773.
-
(2000)
Science
, vol.290
, pp. 767-773
-
-
Kordower, J.H.1
Emborg, M.E.2
Bloch, J.3
Ma, S.Y.4
Chu, Y.P.5
Leventhal, L.6
-
4
-
-
22144477188
-
Recombinant adeno-associated viral vectors in the nervous system
-
Burger C., Nash K., Mandel R.J. Recombinant adeno-associated viral vectors in the nervous system. Hum Gene Ther 2005, 16:781-791.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 781-791
-
-
Burger, C.1
Nash, K.2
Mandel, R.J.3
-
5
-
-
32944470807
-
Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders
-
Mandel R.J., Manfredsson F.P., Foust K.D., Rising A., Reimsnider S., Nash K., et al. Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders. Mol Ther 2006, 13:463-483.
-
(2006)
Mol Ther
, vol.13
, pp. 463-483
-
-
Mandel, R.J.1
Manfredsson, F.P.2
Foust, K.D.3
Rising, A.4
Reimsnider, S.5
Nash, K.6
-
6
-
-
33748290173
-
Gene therapy progress and prospects: non-viral gene therapy by systemic delivery
-
Li S.D., Huang L. Gene therapy progress and prospects: non-viral gene therapy by systemic delivery. Gene Ther 2006, 13:1313-1319.
-
(2006)
Gene Ther
, vol.13
, pp. 1313-1319
-
-
Li, S.D.1
Huang, L.2
-
7
-
-
44649111835
-
Nonviral gene transfection nanoparticles: function and applications in the brain
-
Roy I., Stachowiak M.K., Bergey E.J. Nonviral gene transfection nanoparticles: function and applications in the brain. Nanomedicine 2008, 4:89-97.
-
(2008)
Nanomedicine
, vol.4
, pp. 89-97
-
-
Roy, I.1
Stachowiak, M.K.2
Bergey, E.J.3
-
8
-
-
0003008343
-
Synthetic DNA delivery systems
-
Luo D., Saltzman W.M. Synthetic DNA delivery systems. Nat Biotech 2000, 18:33-37.
-
(2000)
Nat Biotech
, vol.18
, pp. 33-37
-
-
Luo, D.1
Saltzman, W.M.2
-
9
-
-
42049114012
-
Nonviral approaches for neuronal delivery of nucleic acids
-
Bergen J.M., Park I.K., Horner P.J., Pun S.H. Nonviral approaches for neuronal delivery of nucleic acids. Pharm Res 2008, 25:983-998.
-
(2008)
Pharm Res
, vol.25
, pp. 983-998
-
-
Bergen, J.M.1
Park, I.K.2
Horner, P.J.3
Pun, S.H.4
-
10
-
-
63949084384
-
Long-term transgene expression in the central nervous system using DNA nanoparticles
-
Yurek D.M., Fletcher A.M., Smith G.M., Seroogy K.B., Ziady A.G., Molter J., et al. Long-term transgene expression in the central nervous system using DNA nanoparticles. Mol Ther 2009, 17:641-650.
-
(2009)
Mol Ther
, vol.17
, pp. 641-650
-
-
Yurek, D.M.1
Fletcher, A.M.2
Smith, G.M.3
Seroogy, K.B.4
Ziady, A.G.5
Molter, J.6
-
11
-
-
0037409735
-
Polyethylene glycol modified polyethylenimine for improved CNS gene transfer: effects of PEGylation extent
-
Tang G.P., Zeng J.M., Gao S.J., Ma Y.X., Shi L., Li Y., et al. Polyethylene glycol modified polyethylenimine for improved CNS gene transfer: effects of PEGylation extent. Biomaterials 2003, 24:2351-2362.
-
(2003)
Biomaterials
, vol.24
, pp. 2351-2362
-
-
Tang, G.P.1
Zeng, J.M.2
Gao, S.J.3
Ma, Y.X.4
Shi, L.5
Li, Y.6
-
12
-
-
9144230031
-
CNS gene transfer mediated by a novel controlled release system based on DNA complexes of degradable polycation PPE-EA: a comparison with polyethylenimine/DNA complexes
-
Li Y., Wang J., Lee C.G., Wang C.Y., Gao S.J., Tang G.P., et al. CNS gene transfer mediated by a novel controlled release system based on DNA complexes of degradable polycation PPE-EA: a comparison with polyethylenimine/DNA complexes. Gene Ther 2004, 11:109-114.
-
(2004)
Gene Ther
, vol.11
, pp. 109-114
-
-
Li, Y.1
Wang, J.2
Lee, C.G.3
Wang, C.Y.4
Gao, S.J.5
Tang, G.P.6
-
13
-
-
22144447455
-
Design and development of polymers for gene delivery
-
Pack D.W., Hoffman A.S., Pun S., Stayton P.S. Design and development of polymers for gene delivery. Nat Rev Drug Discov 2005, 4:581-593.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 581-593
-
-
Pack, D.W.1
Hoffman, A.S.2
Pun, S.3
Stayton, P.S.4
-
14
-
-
48949098577
-
Gene therapy progress and prospects: synthetic polymer-based systems
-
Schaffert D., Wagner E. Gene therapy progress and prospects: synthetic polymer-based systems. Gene Ther 2008, 15:1131-1138.
-
(2008)
Gene Ther
, vol.15
, pp. 1131-1138
-
-
Schaffert, D.1
Wagner, E.2
-
15
-
-
80054115169
-
HPMA-oligolysine copolymers for gene delivery: optimization of peptide length and polymer molecular weight
-
Johnson R.N., Chu D.S., Shi J., Schellinger J.G., Carlson P.M., Pun S.H. HPMA-oligolysine copolymers for gene delivery: optimization of peptide length and polymer molecular weight. J Control Release 2011, 155:303-311.
-
(2011)
J Control Release
, vol.155
, pp. 303-311
-
-
Johnson, R.N.1
Chu, D.S.2
Shi, J.3
Schellinger, J.G.4
Carlson, P.M.5
Pun, S.H.6
-
16
-
-
0032473403
-
Synthetic peptide-based DNA complexes for nonviral gene delivery
-
Sparrow J.T., Edwards V.V., Tung C., Logan M.J., Wadhwa M.S., Duguid J., et al. Synthetic peptide-based DNA complexes for nonviral gene delivery. Adv Drug Deliv Rev 1998, 30:115-131.
-
(1998)
Adv Drug Deliv Rev
, vol.30
, pp. 115-131
-
-
Sparrow, J.T.1
Edwards, V.V.2
Tung, C.3
Logan, M.J.4
Wadhwa, M.S.5
Duguid, J.6
-
17
-
-
33847192134
-
Peptide-guided gene delivery
-
Martin M.E., Rice K.G. Peptide-guided gene delivery. AAPS J 2007, 9:E18-E29.
-
(2007)
AAPS J
, vol.9
-
-
Martin, M.E.1
Rice, K.G.2
-
18
-
-
33646746706
-
Peptide-enhanced nucleic acid delivery
-
Bergen J.M., Pun S.H. Peptide-enhanced nucleic acid delivery. MRS Bull 2005, 30:663-667.
-
(2005)
MRS Bull
, vol.30
, pp. 663-667
-
-
Bergen, J.M.1
Pun, S.H.2
-
19
-
-
39449130173
-
Analysis of the intracellular barriers encountered by nonviral gene carriers in a model of spatially controlled delivery to neurons
-
Bergen J.M., Pun S.H. Analysis of the intracellular barriers encountered by nonviral gene carriers in a model of spatially controlled delivery to neurons. J Gene Med 2008, 10:187-197.
-
(2008)
J Gene Med
, vol.10
, pp. 187-197
-
-
Bergen, J.M.1
Pun, S.H.2
-
20
-
-
33847396903
-
Quantifying the intracellular transport of viral and nonviral gene vectors in primary neurons
-
Suk J.S., Suh J., Lai S.K., Hanes J. Quantifying the intracellular transport of viral and nonviral gene vectors in primary neurons. Exp Biol Med 2007, 232:461-469.
-
(2007)
Exp Biol Med
, vol.232
, pp. 461-469
-
-
Suk, J.S.1
Suh, J.2
Lai, S.K.3
Hanes, J.4
-
21
-
-
78650476432
-
The proton sponge: a trick to enter cells the viruses did not exploit
-
Behr J.P. The proton sponge: a trick to enter cells the viruses did not exploit. Chimia 1997, 51:34-36.
-
(1997)
Chimia
, vol.51
, pp. 34-36
-
-
Behr, J.P.1
-
22
-
-
0032764932
-
Application of membrane-active peptides for nonviral gene delivery
-
Wagner E. Application of membrane-active peptides for nonviral gene delivery. Adv Drug Deliv Rev 1999, 38:279-289.
-
(1999)
Adv Drug Deliv Rev
, vol.38
, pp. 279-289
-
-
Wagner, E.1
-
23
-
-
0025217893
-
The actions of melittin on membranes
-
Dempsey C.E. The actions of melittin on membranes. Biochim Biophys Acta 1990, 1031:143-161.
-
(1990)
Biochim Biophys Acta
, vol.1031
, pp. 143-161
-
-
Dempsey, C.E.1
-
24
-
-
34447282684
-
Melittin: a membrane-active peptide with diverse functions
-
Raghuraman H., Chattopadhyay A. Melittin: a membrane-active peptide with diverse functions. Biosci Rep 2007, 27:189-223.
-
(2007)
Biosci Rep
, vol.27
, pp. 189-223
-
-
Raghuraman, H.1
Chattopadhyay, A.2
-
25
-
-
0034859096
-
Barrel-stave model or toroidal model? A case study on melittin pores
-
Yang L., Harroun T.A., Weiss T.M., Ding L., Huang H.W. Barrel-stave model or toroidal model? A case study on melittin pores. Biophys J 2001, 81:1475-1485.
-
(2001)
Biophys J
, vol.81
, pp. 1475-1485
-
-
Yang, L.1
Harroun, T.A.2
Weiss, T.M.3
Ding, L.4
Huang, H.W.5
-
26
-
-
79957460418
-
Endosomal escape pathways for delivery of biologicals
-
Varkouhi A.K., Scholte M., Storm G., Haisma H.J. Endosomal escape pathways for delivery of biologicals. J Control Release 2011, 151:220-228.
-
(2011)
J Control Release
, vol.151
, pp. 220-228
-
-
Varkouhi, A.K.1
Scholte, M.2
Storm, G.3
Haisma, H.J.4
-
27
-
-
0029849456
-
Synthetic melittin, its enantio, retro, and retroenantio isomers, and selected chimeric analogs: their antibacterial, hemolytic, and lipid bilayer action
-
Juvvadi P., Vunnam S., Merrifield R.B. Synthetic melittin, its enantio, retro, and retroenantio isomers, and selected chimeric analogs: their antibacterial, hemolytic, and lipid bilayer action. J Am Chem Soc 1996, 118:8989-8997.
-
(1996)
J Am Chem Soc
, vol.118
, pp. 8989-8997
-
-
Juvvadi, P.1
Vunnam, S.2
Merrifield, R.B.3
-
28
-
-
0033521226
-
Thermodynamics of the alpha-helix-coil transition of amphipathic peptides in a membrane environment: implications for the peptide-membrane binding equilibrium
-
Wieprecht T., Apostolov O., Beyermann M., Seelig J. Thermodynamics of the alpha-helix-coil transition of amphipathic peptides in a membrane environment: implications for the peptide-membrane binding equilibrium. J Mol Biol 1999, 294:785-794.
-
(1999)
J Mol Biol
, vol.294
, pp. 785-794
-
-
Wieprecht, T.1
Apostolov, O.2
Beyermann, M.3
Seelig, J.4
-
29
-
-
0035883853
-
Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells
-
Bettinger T., Carlisle R.C., Read M.L., Ogris M., Seymour L.W. Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells. Nucleic Acids Res 2001, 29:3882-3891.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 3882-3891
-
-
Bettinger, T.1
Carlisle, R.C.2
Read, M.L.3
Ogris, M.4
Seymour, L.W.5
-
30
-
-
33646152349
-
Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes
-
Boeckle S., Fahrmeir J., Roedl W., Ogris M., Wagner E. Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes. J Control Release 2006, 112:240-248.
-
(2006)
J Control Release
, vol.112
, pp. 240-248
-
-
Boeckle, S.1
Fahrmeir, J.2
Roedl, W.3
Ogris, M.4
Wagner, E.5
-
31
-
-
33746768781
-
Gene transfer with poly-melittin peptides
-
Chen C.P., Kim J.S., Steenblock E., Liu D., Rice K.G. Gene transfer with poly-melittin peptides. Bioconjug Chem 2006, 17:1057-1062.
-
(2006)
Bioconjug Chem
, vol.17
, pp. 1057-1062
-
-
Chen, C.P.1
Kim, J.S.2
Steenblock, E.3
Liu, D.4
Rice, K.G.5
-
32
-
-
41449109039
-
Breathing life into polycations: functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery
-
Meyer M., Philipp A., Oskuee R., Schmidt C., Wagner E. Breathing life into polycations: functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery. J Am Chem Soc 2008, 130:3272-3273.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 3272-3273
-
-
Meyer, M.1
Philipp, A.2
Oskuee, R.3
Schmidt, C.4
Wagner, E.5
-
33
-
-
0035861750
-
Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors
-
Ogris M., Carlisle R.C., Bettinger T., Seymour L.W. Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors. J Biol Chem 2001, 276:47550-47555.
-
(2001)
J Biol Chem
, vol.276
, pp. 47550-47555
-
-
Ogris, M.1
Carlisle, R.C.2
Bettinger, T.3
Seymour, L.W.4
-
34
-
-
34548735210
-
Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes
-
Rozema D.B., Lewis D.L., Wakefield D.H., Wong S.C., Klein J.J., Roesch P.L., et al. Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes. Proc Natl Acad Sci U S A 2007, 104:12982-12987.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12982-12987
-
-
Rozema, D.B.1
Lewis, D.L.2
Wakefield, D.H.3
Wong, S.C.4
Klein, J.J.5
Roesch, P.L.6
-
35
-
-
78650357926
-
Synthesis of statistical copolymers containing multiple functional peptides for nucleic acid delivery
-
Johnson R.N., Burke R.S., Convertine A.J., Hoffman A.S., Stayton P.S., Pun S.H. Synthesis of statistical copolymers containing multiple functional peptides for nucleic acid delivery. Biomacromolecules 2010, 11:3007-3013.
-
(2010)
Biomacromolecules
, vol.11
, pp. 3007-3013
-
-
Johnson, R.N.1
Burke, R.S.2
Convertine, A.J.3
Hoffman, A.S.4
Stayton, P.S.5
Pun, S.H.6
-
37
-
-
27644481173
-
C-versus N-terminally linked melittin-polyethylenimine conjugates: the site of linkage strongly influences activity of DNA polyplexes
-
Boeckle S., Wagner E., Ogris M. C-versus N-terminally linked melittin-polyethylenimine conjugates: the site of linkage strongly influences activity of DNA polyplexes. J Gene Med 2005, 7:1335-1347.
-
(2005)
J Gene Med
, vol.7
, pp. 1335-1347
-
-
Boeckle, S.1
Wagner, E.2
Ogris, M.3
-
38
-
-
33644887163
-
Molar-mass characterization of cationic polymers for gene delivery by aqueous size-exclusion chromatography
-
Jiang X., van der Horst A., van Steenbergen M.J., Akeroyd N., van Nostrum C.F., Schoenmakers P.J., et al. Molar-mass characterization of cationic polymers for gene delivery by aqueous size-exclusion chromatography. Pharm Res 2006, 23:595-603.
-
(2006)
Pharm Res
, vol.23
, pp. 595-603
-
-
Jiang, X.1
van der Horst, A.2
van Steenbergen, M.J.3
Akeroyd, N.4
van Nostrum, C.F.5
Schoenmakers, P.J.6
-
39
-
-
0021710691
-
Rapid analysis of amino acids using pre-column derivatization
-
Bidlingmeyer B.A., Cohen S.A., Tarvin T.L. Rapid analysis of amino acids using pre-column derivatization. J Chromatogr 1984, 336:93-104.
-
(1984)
J Chromatogr
, vol.336
, pp. 93-104
-
-
Bidlingmeyer, B.A.1
Cohen, S.A.2
Tarvin, T.L.3
-
40
-
-
0242662545
-
A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs
-
Bulmus V., Woodward M., Lin L., Murthy N., Stayton P., Hoffman A. A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs. J Control Release 2003, 93:105-120.
-
(2003)
J Control Release
, vol.93
, pp. 105-120
-
-
Bulmus, V.1
Woodward, M.2
Lin, L.3
Murthy, N.4
Stayton, P.5
Hoffman, A.6
-
41
-
-
0033872875
-
Steric stabilization of poly-L-lysine/DNA complexes by the covalent attachment of semitelechelic poly [N-(2-hydroxypropyl)methacrylamide]
-
Oupicky D., Howard K.A., Konak C., Dash P.R., Ulbrich K., Seymour L.W. Steric stabilization of poly-L-lysine/DNA complexes by the covalent attachment of semitelechelic poly [N-(2-hydroxypropyl)methacrylamide]. Bioconjug Chem 2000, 11:492-501.
-
(2000)
Bioconjug Chem
, vol.11
, pp. 492-501
-
-
Oupicky, D.1
Howard, K.A.2
Konak, C.3
Dash, P.R.4
Ulbrich, K.5
Seymour, L.W.6
-
42
-
-
0346460957
-
Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake
-
Richard J.P., Melikov K., Vives E., Ramos C., Verbeure B., Gait M.J., et al. Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J Biol Chem 2003, 278:585-590.
-
(2003)
J Biol Chem
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
Melikov, K.2
Vives, E.3
Ramos, C.4
Verbeure, B.5
Gait, M.J.6
-
43
-
-
0345704610
-
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
-
Greene L.A., Tischler A.S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A 1976, 73:2424-2428.
-
(1976)
Proc Natl Acad Sci U S A
, vol.73
, pp. 2424-2428
-
-
Greene, L.A.1
Tischler, A.S.2
-
44
-
-
74449086252
-
Targeted nonviral delivery vehicles to neural progenitor cells in the mouse subventricular zone
-
Kwon E.J., Lasiene J., Jacobson B.E., Park I.K., Horner P.J., Pun S.H. Targeted nonviral delivery vehicles to neural progenitor cells in the mouse subventricular zone. Biomaterials 2010, 31:2417-2424.
-
(2010)
Biomaterials
, vol.31
, pp. 2417-2424
-
-
Kwon, E.J.1
Lasiene, J.2
Jacobson, B.E.3
Park, I.K.4
Horner, P.J.5
Pun, S.H.6
-
45
-
-
41149086686
-
Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver
-
Burke R.S., Pun S.H. Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver. Bioconjug Chem 2008, 19:693-704.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 693-704
-
-
Burke, R.S.1
Pun, S.H.2
-
46
-
-
34548590395
-
A dimethylmaleic acid-melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential
-
Meyer M., Zintchenko A., Ogris M., Wagner E. A dimethylmaleic acid-melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential. J Gene Med 2007, 9:797-805.
-
(2007)
J Gene Med
, vol.9
, pp. 797-805
-
-
Meyer, M.1
Zintchenko, A.2
Ogris, M.3
Wagner, E.4
-
47
-
-
84859813541
-
Truncated peptides from melittin and its analog with high lytic activity at endosomal pH enhance branched polyethylenimine-mediated gene transfection
-
Tan Y.X., Chen C., Wang Y.L., Lin S., Wang Y., Li S.B., et al. Truncated peptides from melittin and its analog with high lytic activity at endosomal pH enhance branched polyethylenimine-mediated gene transfection. J Gene Med 2012, 14:241-250.
-
(2012)
J Gene Med
, vol.14
, pp. 241-250
-
-
Tan, Y.X.1
Chen, C.2
Wang, Y.L.3
Lin, S.4
Wang, Y.5
Li, S.B.6
|