Truncated peptides from melittin and its analog with high lytic activity at endosomal pH enhance branched polyethylenimine-mediated gene transfection

Journal of Gene Medicine

Volumn 14, Issue 4, 2012, Pages 241-250

  Tan, Ying Xia ^a   Chen, Chong ^a   Wang, Ying Li ^a   Lin, Song ^b   Wang, Yang ^b   Li, Su Bo ^a   Jin, Xiao Pan ^a   Gao, Hong Wei ^a   Du, Fu Sheng ^b   Gong, Feng ^a   Ji, Shou Ping ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Branched polyethylenimine (BPEI); Cell penetrating peptides; Endosome release; Florae; Gene transfection; Melittin; Truncated peptides

Indexed keywords

CALCEIN; MELITTIN; PLASMID DNA; POLYETHYLENEIMINE;

ACIDITY; ALPHA HELIX; ANIMAL CELL; ARTICLE; CELL DISRUPTION; CELL MIGRATION; CELL PH; CELLULAR DISTRIBUTION; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; ENDOSOME; GENETIC TRANSFECTION; HEMOLYSIS; HUMAN; HUMAN CELL; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTEIN SECRETION; ZETA POTENTIAL;

ANIMALS; CELL LINE; CELL-PENETRATING PEPTIDES; CHO CELLS; CIRCULAR DICHROISM; CRICETINAE; DNA; DRUG CARRIERS; ENDOSOMES; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MELITTEN; POLYETHYLENEIMINE; TRANSFECTION;

EID: 84859813541     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.2609     Document Type: Article

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