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Volumn 11, Issue 1, 2013, Pages 1-15

Resveratrol: Botanical origin, pharmacological activity and applications

Author keywords

Applications; Botanical origin; Pharmacological effects; Resveratrol

Indexed keywords

CASPASE 3; CASPASE 9; CLOFARABINE; CYCLIN D1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEMOGLOBIN A1C; NITRIC OXIDE; PROTEIN P21; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RESVERATROL; SCATTER FACTOR RECEPTOR; SIRTUIN 1; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84872376924     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(13)60001-1     Document Type: Article
Times cited : (76)

References (145)
  • 1
    • 77956716582 scopus 로고    scopus 로고
    • Dietary polyphenols: Focus on resveratrol, a promising agent in the prevention of cardiovascular diseases and control of glucose homeostasis [J]
    • Borriello A, Cucciolla V, Ragione FD, et al. Dietary polyphenols: Focus on resveratrol, a promising agent in the prevention of cardiovascular diseases and control of glucose homeostasis [J]. Nutr Metab Cardiovas 2010, 20(8):618-625.
    • (2010) Nutr Metab Cardiovas , vol.20 , Issue.8 , pp. 618-625
    • Borriello, A.1    Cucciolla, V.2    Ragione, F.D.3
  • 2
    • 0017774510 scopus 로고
    • A new class of phytoalexins from grapevines [J]
    • Langcake P, Pryce R A new class of phytoalexins from grapevines [J]. Cellul Mol Life Sci 1977, 33(2):151-152.
    • (1977) Cellul Mol Life Sci , vol.33 , Issue.2 , pp. 151-152
    • Langcake, P.1    Pryce, R.2
  • 3
    • 56749153720 scopus 로고    scopus 로고
    • Effect of food on the pharmacokinetic profile of trans-resveratrol [J]
    • Silva MV, Loureiro A, Falcao A, et al. Effect of food on the pharmacokinetic profile of trans-resveratrol [J]. Int J Clin Pharmacol Ther 2008, 46(11):564-570.
    • (2008) Int J Clin Pharmacol Ther , vol.46 , Issue.11 , pp. 564-570
    • Silva, M.V.1    Loureiro, A.2    Falcao, A.3
  • 4
    • 79952661832 scopus 로고    scopus 로고
    • The grape antioxidant resveratrol for skin disorders: Promise, prospects, and challenges [J]
    • Ndiaye M, Philippe C, Mukhtar H, et al. The grape antioxidant resveratrol for skin disorders: Promise, prospects, and challenges [J]. Arch Biochem Biophys 2011, 508(2):164-170.
    • (2011) Arch Biochem Biophys , vol.508 , Issue.2 , pp. 164-170
    • Ndiaye, M.1    Philippe, C.2    Mukhtar, H.3
  • 5
    • 70450123699 scopus 로고    scopus 로고
    • Resveratrol: A natural polyphenol with multiple chemopreventive properties [J]
    • Brisdelli F, Andrea GD, Bozzi A Resveratrol: A natural polyphenol with multiple chemopreventive properties [J]. Curr Drug Metab 2009, 10(6):530-546.
    • (2009) Curr Drug Metab , vol.10 , Issue.6 , pp. 530-546
    • Brisdelli, F.1    Andrea, G.D.2    Bozzi, A.3
  • 6
    • 84862786365 scopus 로고    scopus 로고
    • Resveratrol attenuates brain damage in a rat model of focal cerebral ischemia via up-regulation of hippocampal Bcl-2 [J]
    • Li Z, Pang L, Fang F, et al. Resveratrol attenuates brain damage in a rat model of focal cerebral ischemia via up-regulation of hippocampal Bcl-2 [J]. Brain Res 2012, 1450:116-124.
    • (2012) Brain Res , vol.1450 , pp. 116-124
    • Li, Z.1    Pang, L.2    Fang, F.3
  • 7
    • 84863324004 scopus 로고    scopus 로고
    • Using PDE inhibitors to harness the benefits of calorie restriction: lessons from resveratrol [J]
    • Chung JH Using PDE inhibitors to harness the benefits of calorie restriction: lessons from resveratrol [J]. Aging 2012, 4(3):144-145.
    • (2012) Aging , vol.4 , Issue.3 , pp. 144-145
    • Chung, J.H.1
  • 8
    • 84860333568 scopus 로고    scopus 로고
    • Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity [J]
    • Jeong JK, Moon MH, Bae BC, et al. Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity [J]. Neurosci Res 2012, 73(2):99-105.
    • (2012) Neurosci Res , vol.73 , Issue.2 , pp. 99-105
    • Jeong, J.K.1    Moon, M.H.2    Bae, B.C.3
  • 10
    • 84863328591 scopus 로고    scopus 로고
    • The journey of resveratrol from yeast to human [J]
    • Timmers S, Auwerx O, Schrauwen P The journey of resveratrol from yeast to human [J]. Aging 2012, 4(3):1-13.
    • (2012) Aging , vol.4 , Issue.3 , pp. 1-13
    • Timmers, S.1    Auwerx, O.2    Schrauwen, P.3
  • 11
    • 84867865164 scopus 로고    scopus 로고
    • Resveratrol role in cardiovascular and metabolic health and potential mechanisms of action [J]
    • Xu Q, Si LY Resveratrol role in cardiovascular and metabolic health and potential mechanisms of action [J]. Nutr Res 2012, 32(9):648-658.
    • (2012) Nutr Res , vol.32 , Issue.9 , pp. 648-658
    • Xu, Q.1    Si, L.Y.2
  • 12
    • 0141631443 scopus 로고    scopus 로고
    • Resveratrol in raw and baked blueberries and bilberries [J]
    • Lyons M, Yu C, Toma RB, et al. Resveratrol in raw and baked blueberries and bilberries [J]. J Agric Food Chem 2003, 51(20):5867-5870.
    • (2003) J Agric Food Chem , vol.51 , Issue.20 , pp. 5867-5870
    • Lyons, M.1    Yu, C.2    Toma, R.B.3
  • 13
    • 6944250259 scopus 로고    scopus 로고
    • Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies [J]
    • Aggarwal BB, Bhardwaj A, Aggarwal RS, et al. Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies [J]. Anticancer Res 2004, 24(5A):2783-2840.
    • (2004) Anticancer Res , vol.24 , Issue.5 A , pp. 2783-2840
    • Aggarwal, B.B.1    Bhardwaj, A.2    Aggarwal, R.S.3
  • 14
    • 34247844600 scopus 로고    scopus 로고
    • Antioxidant activity of Sicilian pistachio (Pistacia vera L. var. Bronte) nut extract and its bioactive components [J]
    • Gentile C, Tesoriere L, Butera D, et al. Antioxidant activity of Sicilian pistachio (Pistacia vera L. var. Bronte) nut extract and its bioactive components [J]. J Agric Food Chem 2007, 55(3):643-648.
    • (2007) J Agric Food Chem , vol.55 , Issue.3 , pp. 643-648
    • Gentile, C.1    Tesoriere, L.2    Butera, D.3
  • 15
    • 0032801975 scopus 로고    scopus 로고
    • The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury [J]
    • Ray PS, Maulik G, Cordis GA, et al. The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury [J]. Free Radical Bio Med 1999, 27(1-2):160-169.
    • (1999) Free Radical Bio Med , vol.27 , Issue.1-2 , pp. 160-169
    • Ray, P.S.1    Maulik, G.2    Cordis, G.A.3
  • 16
    • 78649346690 scopus 로고    scopus 로고
    • Red wine antioxidant resveratrol-modified cardiac stem cells regenerate infarcted myocardium [J]
    • Gurusamy N, Ray D, Lekli I, et al. Red wine antioxidant resveratrol-modified cardiac stem cells regenerate infarcted myocardium [J]. J Cell Mol Med 2010, 14(9):2235-2239.
    • (2010) J Cell Mol Med , vol.14 , Issue.9 , pp. 2235-2239
    • Gurusamy, N.1    Ray, D.2    Lekli, I.3
  • 17
    • 0036086657 scopus 로고    scopus 로고
    • Pharmacological preconditioning with resveratrol: role of nitric oxide [J]
    • Hattori R, Otani H, Maulik N, et al. Pharmacological preconditioning with resveratrol: role of nitric oxide [J]. Am J Physiol Heart Circ Physiol 2002, 282(6):1988-1995.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282 , Issue.6 , pp. 1988-1995
    • Hattori, R.1    Otani, H.2    Maulik, N.3
  • 18
    • 34250857969 scopus 로고    scopus 로고
    • Prevention of concentric hypertrophy and diastolic impairment in aortic-banded rats treated with resveratrol [J]
    • Juric D, Wojciechowski P, Das DK, et al. Prevention of concentric hypertrophy and diastolic impairment in aortic-banded rats treated with resveratrol [J]. Am J Physiol-Heart C 2007, 292(5):2138-2143.
    • (2007) Am J Physiol-Heart C , vol.292 , Issue.5 , pp. 2138-2143
    • Juric, D.1    Wojciechowski, P.2    Das, D.K.3
  • 19
    • 70349260424 scopus 로고    scopus 로고
    • Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats [J]
    • Csiszar A, Labinskyy N, Olson S, et al. Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats [J]. Hypertension 2009, 54(3):668-675.
    • (2009) Hypertension , vol.54 , Issue.3 , pp. 668-675
    • Csiszar, A.1    Labinskyy, N.2    Olson, S.3
  • 20
    • 33749265695 scopus 로고    scopus 로고
    • Cardioprotective effect of resveratrol via HO-1 expression involves p38 map kinase and PI-3-kinase signaling, but does not involve NFκB [J]
    • Das S, Fraga CG, Das DK Cardioprotective effect of resveratrol via HO-1 expression involves p38 map kinase and PI-3-kinase signaling, but does not involve NFκB [J]. Free Radic Res 2006, 40(10):1066-1075.
    • (2006) Free Radic Res , vol.40 , Issue.10 , pp. 1066-1075
    • Das, S.1    Fraga, C.G.2    Das, D.K.3
  • 21
    • 34547101726 scopus 로고    scopus 로고
    • Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase [J]
    • Thirunavukkarasu M, Penumathsa SV, Koneru S, et al. Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase [J]. Free Radic Bio Med 2007, 43(5):720-729.
    • (2007) Free Radic Bio Med , vol.43 , Issue.5 , pp. 720-729
    • Thirunavukkarasu, M.1    Penumathsa, S.V.2    Koneru, S.3
  • 22
    • 77953741269 scopus 로고    scopus 로고
    • Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2 [J]
    • Ungvari Z, Bagi Z, Feher A, et al. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2 [J]. Am J Physiol-Heart C 2010, 299(1):18-24.
    • (2010) Am J Physiol-Heart C , vol.299 , Issue.1 , pp. 18-24
    • Ungvari, Z.1    Bagi, Z.2    Feher, A.3
  • 23
    • 34250842528 scopus 로고    scopus 로고
    • Resveratrol increases vascular oxidative stress resistance [J]
    • Ungvari Z, Orosz Z, Rivera A, et al. Resveratrol increases vascular oxidative stress resistance [J]. Am J Physiol-Heart C 2007, 292(5):2417-2424.
    • (2007) Am J Physiol-Heart C , vol.292 , Issue.5 , pp. 2417-2424
    • Ungvari, Z.1    Orosz, Z.2    Rivera, A.3
  • 24
    • 34147182364 scopus 로고    scopus 로고
    • Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages [J]
    • Chow SE, Hshu YC, Wang JS, et al. Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages [J]. J Appl Physiol 2007, 102(4):1520-1527.
    • (2007) J Appl Physiol , vol.102 , Issue.4 , pp. 1520-1527
    • Chow, S.E.1    Hshu, Y.C.2    Wang, J.S.3
  • 25
    • 70350464512 scopus 로고    scopus 로고
    • Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells [J]
    • Ungvari Z, Labinskyy N, Mukhopadhyay P, et al. Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells [J]. Am J Physiol-Heart C 2009, 297(5):1876-1881.
    • (2009) Am J Physiol-Heart C , vol.297 , Issue.5 , pp. 1876-1881
    • Ungvari, Z.1    Labinskyy, N.2    Mukhopadhyay, P.3
  • 26
    • 49249100288 scopus 로고    scopus 로고
    • Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations [J]
    • Csiszar A, Labinskyy N, Podlutsky A, et al. Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations [J]. Am J Physiol-Heart C 2008, 294(6):2721-2735.
    • (2008) Am J Physiol-Heart C , vol.294 , Issue.6 , pp. 2721-2735
    • Csiszar, A.1    Labinskyy, N.2    Podlutsky, A.3
  • 27
    • 33749365317 scopus 로고    scopus 로고
    • Resveratrol attenuates TNF-a-induced activation of coronary arterial endothelial cells: role of NF-κB inhibition [J]
    • Csiszar A, Smith K, Labinskyy N, et al. Resveratrol attenuates TNF-a-induced activation of coronary arterial endothelial cells: role of NF-κB inhibition [J]. Am J Physiol-Heart C 2006, 291(4):1694-1699.
    • (2006) Am J Physiol-Heart C , vol.291 , Issue.4 , pp. 1694-1699
    • Csiszar, A.1    Smith, K.2    Labinskyy, N.3
  • 28
    • 0031769485 scopus 로고    scopus 로고
    • Activity in vitro of resveratrol on granulocyte and monocyte adhesion to endothelium [J]
    • Ferrero ME, Bertelli A, Fulgenzi A, et al. Activity in vitro of resveratrol on granulocyte and monocyte adhesion to endothelium [J]. Am J Clin Nutr 1998, 68(6):1208-1214.
    • (1998) Am J Clin Nutr , vol.68 , Issue.6 , pp. 1208-1214
    • Ferrero, M.E.1    Bertelli, A.2    Fulgenzi, A.3
  • 29
    • 0034660659 scopus 로고    scopus 로고
    • Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-κB, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation [J]
    • Manna SK, Mukhopadhyay A, Aggarwal BB Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-κB, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation [J]. J Immunol 2000, 164(12):6509-6519.
    • (2000) J Immunol , vol.164 , Issue.12 , pp. 6509-6519
    • Manna, S.K.1    Mukhopadhyay, A.2    Aggarwal, B.B.3
  • 30
    • 33745273633 scopus 로고    scopus 로고
    • Resveratrol suppresses tumor necrosis factor-a-induced fractalkine expression in endothelial cells [J]
    • Moon SO, Kim W, Sung MJ, et al. Resveratrol suppresses tumor necrosis factor-a-induced fractalkine expression in endothelial cells [J]. Mol Pharmacol 2006, 70(1):112-119.
    • (2006) Mol Pharmacol , vol.70 , Issue.1 , pp. 112-119
    • Moon, S.O.1    Kim, W.2    Sung, M.J.3
  • 31
    • 0037376409 scopus 로고    scopus 로고
    • Resveratrol, a red wine constituent polyphenol, prevents superoxide-dependent inflammatory responses induced by ischemia/reperfusion, platelet-activating factor, or oxidants [J]
    • Shigematsu S, Ishida S, Hara M, et al. Resveratrol, a red wine constituent polyphenol, prevents superoxide-dependent inflammatory responses induced by ischemia/reperfusion, platelet-activating factor, or oxidants [J]. Free Radical Bio Med 2003, 34(7):810-817.
    • (2003) Free Radical Bio Med , vol.34 , Issue.7 , pp. 810-817
    • Shigematsu, S.1    Ishida, S.2    Hara, M.3
  • 32
    • 0033023541 scopus 로고    scopus 로고
    • Suppression of nitric oxide synthase and the down-regulation of the activation of NFκB in macrophages by resveratrol [J]
    • Tsai SH, Lin-Shiau SY, Lin JK Suppression of nitric oxide synthase and the down-regulation of the activation of NFκB in macrophages by resveratrol [J]. Brit J Pharmacol 1999, 126(3):673-680.
    • (1999) Brit J Pharmacol , vol.126 , Issue.3 , pp. 673-680
    • Tsai, S.H.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 33
    • 34547178903 scopus 로고    scopus 로고
    • 2 production promotes endothelial NF-κB activation in aged rat arteries [J]
    • 2 production promotes endothelial NF-κB activation in aged rat arteries [J]. Am J Physiol-Heart C 2007, 293(1):37-47.
    • (2007) Am J Physiol-Heart C , vol.293 , Issue.1 , pp. 37-47
    • Ungvari, Z.1    Orosz, Z.2    Labinskyy, N.3
  • 34
    • 27744438212 scopus 로고    scopus 로고
    • Resveratrol suppresses IL-6-induced ICAM-1 gene expression in endothelial cells: effects on the inhibition of STAT3 phosphorylation [J]
    • Wung B, Hsu M, Wu C, et al. Resveratrol suppresses IL-6-induced ICAM-1 gene expression in endothelial cells: effects on the inhibition of STAT3 phosphorylation [J]. Life Sci 2005, 78(4):389-397.
    • (2005) Life Sci , vol.78 , Issue.4 , pp. 389-397
    • Wung, B.1    Hsu, M.2    Wu, C.3
  • 35
    • 0037167677 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase [J]
    • Wallerath T, Deckert G, Ternes T, et al. Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase [J]. Circulation 2002, 106(13):1652-1658.
    • (2002) Circulation , vol.106 , Issue.13 , pp. 1652-1658
    • Wallerath, T.1    Deckert, G.2    Ternes, T.3
  • 36
    • 77950469163 scopus 로고    scopus 로고
    • Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and NADPH oxidase subunit (Nox4) [J]
    • Spanier G, Xu H, Xia N, et al. Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and NADPH oxidase subunit (Nox4) [J]. J Physiol Pharmacol 2009, 60(Suppl 4):111-116.
    • (2009) J Physiol Pharmacol , vol.60 , Issue.SUPPL 4 , pp. 111-116
    • Spanier, G.1    Xu, H.2    Xia, N.3
  • 37
    • 43649087274 scopus 로고    scopus 로고
    • High glucose downregulates endothelial progenitor cell number via SIRT1 [J]
    • Balestrieri ML, Rienzo M, Felice F, et al. High glucose downregulates endothelial progenitor cell number via SIRT1 [J]. BBA-Proteins Proteom 2008, 1784(6):936-945.
    • (2008) BBA-Proteins Proteom , vol.1784 , Issue.6 , pp. 936-945
    • Balestrieri, M.L.1    Rienzo, M.2    Felice, F.3
  • 38
    • 77249158771 scopus 로고    scopus 로고
    • SIRT1 regulates oxidant-and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol [J]
    • Arunachalam G, Yao H, Sundar IK, et al. SIRT1 regulates oxidant-and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol [J]. Biochem Biophys Res Commun 2010, 393(1):66-72.
    • (2010) Biochem Biophys Res Commun , vol.393 , Issue.1 , pp. 66-72
    • Arunachalam, G.1    Yao, H.2    Sundar, I.K.3
  • 39
    • 67650091375 scopus 로고    scopus 로고
    • Resveratrol induces mitochondrial biogenesis in endothelial cells [J]
    • Csiszar A, Labinskyy N, Pinto JT, et al. Resveratrol induces mitochondrial biogenesis in endothelial cells [J]. Am J Physiol-Heart C 2009, 297(1):13-20.
    • (2009) Am J Physiol-Heart C , vol.297 , Issue.1 , pp. 13-20
    • Csiszar, A.1    Labinskyy, N.2    Pinto, J.T.3
  • 40
    • 74249099068 scopus 로고    scopus 로고
    • Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype [J]
    • Gracia Sancho J, Villarreal G, Zhang Y, et al. Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype [J]. Cardiovasc Res 2010, 85(3):514-519.
    • (2010) Cardiovasc Res , vol.85 , Issue.3 , pp. 514-519
    • Gracia Sancho, J.1    Villarreal, G.2    Zhang, Y.3
  • 41
    • 77949357437 scopus 로고    scopus 로고
    • Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway [J]
    • Gurusamy N, Lekli I, Mukherjee S, et al. Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway [J]. Cardiovasc Res 2010, 86(1):103-112.
    • (2010) Cardiovasc Res , vol.86 , Issue.1 , pp. 103-112
    • Gurusamy, N.1    Lekli, I.2    Mukherjee, S.3
  • 42
    • 77649213393 scopus 로고    scopus 로고
    • Metabolic effects of resveratrol in mammals-a link between improved insulin action and aging [J]
    • Frojdo S, Durand C, Pirola L Metabolic effects of resveratrol in mammals-a link between improved insulin action and aging [J]. Curr Aging Sci 2008, 1(3):145-151.
    • (2008) Curr Aging Sci , vol.1 , Issue.3 , pp. 145-151
    • Frojdo, S.1    Durand, C.2    Pirola, L.3
  • 43
    • 77952321187 scopus 로고    scopus 로고
    • Resveratrol, obesity and diabetes [J]
    • Szkudelska K, Szkudelski T Resveratrol, obesity and diabetes [J]. Eur J Pharmacol 2010, 635(1):1-8.
    • (2010) Eur J Pharmacol , vol.635 , Issue.1 , pp. 1-8
    • Szkudelska, K.1    Szkudelski, T.2
  • 44
    • 57349153327 scopus 로고    scopus 로고
    • Beneficial effects of resveratrol on atherosclerosis [J]
    • Fan E, Zhang L, Jiang S, et al. Beneficial effects of resveratrol on atherosclerosis [J]. J Med Food 2008, 11(4):610-614.
    • (2008) J Med Food , vol.11 , Issue.4 , pp. 610-614
    • Fan, E.1    Zhang, L.2    Jiang, S.3
  • 45
    • 39149137233 scopus 로고    scopus 로고
    • Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelin [J]
    • Lekli I, Szabo G, Juhasz B, et al. Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelin [J]. Am J Physiol-Heart C 2008, 294(2):H859-H866.
    • (2008) Am J Physiol-Heart C , vol.294 , Issue.2
    • Lekli, I.1    Szabo, G.2    Juhasz, B.3
  • 46
    • 78650636700 scopus 로고    scopus 로고
    • Antidiabetic activity of resveratrol, a known SIRT1 activator in a genetic model for type 2 diabetes [J]
    • Sharma S, Misra CS, Arumugam S, et al. Antidiabetic activity of resveratrol, a known SIRT1 activator in a genetic model for type 2 diabetes [J]. Phytother Res 2011, 25(1):67-73.
    • (2011) Phytother Res , vol.25 , Issue.1 , pp. 67-73
    • Sharma, S.1    Misra, C.S.2    Arumugam, S.3
  • 47
    • 54049155669 scopus 로고    scopus 로고
    • Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced experimental diabetic rats [J]
    • Palsamy P, Subramanian S Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced experimental diabetic rats [J]. Biomed Pharmacother 2008, 62(9):598-605.
    • (2008) Biomed Pharmacother , vol.62 , Issue.9 , pp. 598-605
    • Palsamy, P.1    Subramanian, S.2
  • 48
    • 62549115284 scopus 로고    scopus 로고
    • Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats [J]
    • Palsamy P, Subramanian S Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats [J]. Chem-Biol Interact 2009, 179(2-3):356-362.
    • (2009) Chem-Biol Interact , vol.179 , Issue.2-3 , pp. 356-362
    • Palsamy, P.1    Subramanian, S.2
  • 49
    • 77953644361 scopus 로고    scopus 로고
    • Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic β-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats [J]
    • Palsamy P, Subramanian S Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic β-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats [J]. J Cell Physiol 2010, 224(2):423-432.
    • (2010) J Cell Physiol , vol.224 , Issue.2 , pp. 423-432
    • Palsamy, P.1    Subramanian, S.2
  • 50
    • 57149123016 scopus 로고    scopus 로고
    • Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium [J]
    • Penumathsa SV, Thirunavukkarasu M, Zhan L, et al. Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium [J]. J Cell Mol Med 2008, 12(6a):2350-2361.
    • (2008) J Cell Mol Med , vol.12 , Issue.6 A , pp. 2350-2361
    • Penumathsa, S.V.1    Thirunavukkarasu, M.2    Zhan, L.3
  • 51
    • 44349141200 scopus 로고    scopus 로고
    • The effects of chronic resveratrol treatment on vascular responsiveness of streptozotocin-induced diabetic rats [J]
    • Silan C The effects of chronic resveratrol treatment on vascular responsiveness of streptozotocin-induced diabetic rats [J]. Bio Pharm Bull 2008, 31(5):897-902.
    • (2008) Bio Pharm Bull , vol.31 , Issue.5 , pp. 897-902
    • Silan, C.1
  • 52
    • 33744946526 scopus 로고    scopus 로고
    • Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats [J]
    • Su HC, Hung LM, Chen JK Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats [J]. Am J Physiol-Endoc M 2006, 290(6):1339-1346.
    • (2006) Am J Physiol-Endoc M , vol.290 , Issue.6 , pp. 1339-1346
    • Su, H.C.1    Hung, L.M.2    Chen, J.K.3
  • 53
    • 33750455515 scopus 로고    scopus 로고
    • Resveratrol inhibits insulin secretion from rat pancreatic islets [J]
    • Szkudelski T Resveratrol inhibits insulin secretion from rat pancreatic islets [J]. Eur J Pharmacol 2006, 552(1):176-181.
    • (2006) Eur J Pharmacol , vol.552 , Issue.1 , pp. 176-181
    • Szkudelski, T.1
  • 54
    • 77950841396 scopus 로고    scopus 로고
    • Effects of different doses of resveratrol on body fat and serum parameters in rats fed a hypercaloric diet [J]
    • Macarulla MT, Alberdi G, Gomez S, et al. Effects of different doses of resveratrol on body fat and serum parameters in rats fed a hypercaloric diet [J]. J Physiol Biochem 2009, 65(4):369-376.
    • (2009) J Physiol Biochem , vol.65 , Issue.4 , pp. 369-376
    • Macarulla, M.T.1    Alberdi, G.2    Gomez, S.3
  • 55
    • 67349286501 scopus 로고    scopus 로고
    • Resveratrol toxicity: effects on risk factors for atherosclerosis and hepatic oxidative stress in standard and high-fat diets [J]
    • Rocha K, Souza G, Ebaid G, et al. Resveratrol toxicity: effects on risk factors for atherosclerosis and hepatic oxidative stress in standard and high-fat diets [J]. Food Chem Toxicol 2009, 47(6):1362-1367.
    • (2009) Food Chem Toxicol , vol.47 , Issue.6 , pp. 1362-1367
    • Rocha, K.1    Souza, G.2    Ebaid, G.3
  • 56
    • 44849131936 scopus 로고    scopus 로고
    • Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase1 [J]
    • Shang J, Chen L, Xiao F, et al. Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase1 [J]. Acta Pharmacol Sin 2008, 29(6):698-706.
    • (2008) Acta Pharmacol Sin , vol.29 , Issue.6 , pp. 698-706
    • Shang, J.1    Chen, L.2    Xiao, F.3
  • 57
    • 63249112836 scopus 로고    scopus 로고
    • Overexpression of SIRT1 protects pancreatic β-cells against cytokine toxicity by suppressing the nuclear factor-κB signaling pathway [J]
    • Lee JH, Song MY, Song EK, et al. Overexpression of SIRT1 protects pancreatic β-cells against cytokine toxicity by suppressing the nuclear factor-κB signaling pathway [J]. Diabetes 2009, 58(2):344-351.
    • (2009) Diabetes , vol.58 , Issue.2 , pp. 344-351
    • Lee, J.H.1    Song, M.Y.2    Song, E.K.3
  • 58
    • 33750502270 scopus 로고    scopus 로고
    • Oxidative stress and impaired insulin secretion in type 2 diabetes [J]
    • Robertson RP Oxidative stress and impaired insulin secretion in type 2 diabetes [J]. Curr Opin Pharmacol 2006, 6(6):615-619.
    • (2006) Curr Opin Pharmacol , vol.6 , Issue.6 , pp. 615-619
    • Robertson, R.P.1
  • 59
    • 77953734595 scopus 로고    scopus 로고
    • Endothelial Nrf2 activation: a new target for resveratrol[J]?
    • Hasko G, Pacher P Endothelial Nrf2 activation: a new target for resveratrol[J]?. Am J Physiol-Heart C 2010, 299(1):H10-H12.
    • (2010) Am J Physiol-Heart C , vol.299 , Issue.1
    • Hasko, G.1    Pacher, P.2
  • 60
    • 0019940467 scopus 로고
    • Effects of stilbene components of the roots of Polygonum cuspidatum Sieb. et Zucc. on lipid metabolism [J]
    • Arichi H, Kimura Y, Okuda H, et al. Effects of stilbene components of the roots of Polygonum cuspidatum Sieb. et Zucc. on lipid metabolism [J]. Chem Pharm Bull (Tokyo) 1982, 30(5):1766-1770.
    • (1982) Chem Pharm Bull (Tokyo) , vol.30 , Issue.5 , pp. 1766-1770
    • Arichi, H.1    Kimura, Y.2    Okuda, H.3
  • 61
    • 0021046446 scopus 로고
    • Effects of stilbene components of roots of Polygonum ssp. on liver injury in peroxidized oil-fed rats [J]
    • Kimura Y, Ohminami H, Okuda H, et al. Effects of stilbene components of roots of Polygonum ssp. on liver injury in peroxidized oil-fed rats [J]. Planta Med 1983, 49(1):51-54.
    • (1983) Planta Med , vol.49 , Issue.1 , pp. 51-54
    • Kimura, Y.1    Ohminami, H.2    Okuda, H.3
  • 62
    • 0029103838 scopus 로고
    • Does wine work [J]?
    • Goldberg DM Does wine work [J]?. Clin Chem 1995, 41(1):14-16.
    • (1995) Clin Chem , vol.41 , Issue.1 , pp. 14-16
    • Goldberg, D.M.1
  • 63
    • 0030963473 scopus 로고    scopus 로고
    • Resveratrol: a molecule whose time has come? And gone[J]?
    • Soleas GJ, Diamandis EP, Goldberg DM Resveratrol: a molecule whose time has come? And gone[J]?. Clin Biochem 1997, 30(2):91-113.
    • (1997) Clin Biochem , vol.30 , Issue.2 , pp. 91-113
    • Soleas, G.J.1    Diamandis, E.P.2    Goldberg, D.M.3
  • 64
    • 50649112638 scopus 로고    scopus 로고
    • SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase [J]
    • Hou X, Xu S, Maitland-Toolan KA, et al. SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase [J]. J Biol Chem 2008, 283(29):20015-20026.
    • (2008) J Biol Chem , vol.283 , Issue.29 , pp. 20015-20026
    • Hou, X.1    Xu, S.2    Maitland-Toolan, K.A.3
  • 65
    • 34447100874 scopus 로고    scopus 로고
    • Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D [J]
    • Trincheri NF, Nicotra G, Follo C, et al. Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D [J]. Carcinogenesis 2007, 28(5):922-931.
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 922-931
    • Trincheri, N.F.1    Nicotra, G.2    Follo, C.3
  • 66
    • 34548827057 scopus 로고    scopus 로고
    • Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria [J]
    • Ginkel V, Sareen D, Subramanian L, et al. Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria [J]. Clin Cancer Res 2007, 13(17):5162-5169.
    • (2007) Clin Cancer Res , vol.13 , Issue.17 , pp. 5162-5169
    • Ginkel, V.1    Sareen, D.2    Subramanian, L.3
  • 67
    • 84869788456 scopus 로고    scopus 로고
    • Antiproliferative and cytotoxic effects of resveratrol in mitochondria-mediated apoptosis in rat B103 neuroblastoma cells [J]
    • Rahman MA, Kim NH, Kim SH, et al. Antiproliferative and cytotoxic effects of resveratrol in mitochondria-mediated apoptosis in rat B103 neuroblastoma cells [J]. Korean J Physiol Pha 2012, 16(5):321-326.
    • (2012) Korean J Physiol Pha , vol.16 , Issue.5 , pp. 321-326
    • Rahman, M.A.1    Kim, N.H.2    Kim, S.H.3
  • 68
    • 84869868260 scopus 로고    scopus 로고
    • Synergistic anti-cancer effects of resveratrol and chemotherapeutic agent clofarabine against human malignant mesothelioma MSTO-211H cells [J]
    • Lee YJ, Lee YJ, Im JH, et al. Synergistic anti-cancer effects of resveratrol and chemotherapeutic agent clofarabine against human malignant mesothelioma MSTO-211H cells [J]. Food Chem Toxicol 2013, 52C:61-68.
    • (2013) Food Chem Toxicol , vol.52 C , pp. 61-68
    • Lee, Y.J.1    Lee, Y.J.2    Im, J.H.3
  • 69
    • 84872393155 scopus 로고    scopus 로고
    • Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis [J]
    • pii: S0300-483X(12)00373-3.
    • Wang H, Zhang H, Tang L, et al. Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis [J]. Toxicology 2012, pii: S0300-483X(12)00373-3.
    • (2012) Toxicology
    • Wang, H.1    Zhang, H.2    Tang, L.3
  • 70
    • 34547107359 scopus 로고    scopus 로고
    • Forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol [J]
    • Su JL, Yang CY, Zhao M, et al. Forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol [J]. J Biol Chem 2007, 282(27):19385-19398.
    • (2007) J Biol Chem , vol.282 , Issue.27 , pp. 19385-19398
    • Su, J.L.1    Yang, C.Y.2    Zhao, M.3
  • 71
    • 33847665667 scopus 로고    scopus 로고
    • Resveratrol inhibits pancreatic cancer cell proliferation through transcriptional induction of macrophage inhibitory cytokine-1 [J]
    • Golkar L, Ding XZ, Ujiki MB, et al. Resveratrol inhibits pancreatic cancer cell proliferation through transcriptional induction of macrophage inhibitory cytokine-1 [J]. J Surg Res 2007, 138(2):163-169.
    • (2007) J Surg Res , vol.138 , Issue.2 , pp. 163-169
    • Golkar, L.1    Ding, X.Z.2    Ujiki, M.B.3
  • 72
    • 33947197883 scopus 로고    scopus 로고
    • Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells [J]
    • Bhardwaj A, Sethi G, Vadhan-Raj S, et al. Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells [J]. Blood 2007, 109(6):2293-2302.
    • (2007) Blood , vol.109 , Issue.6 , pp. 2293-2302
    • Bhardwaj, A.1    Sethi, G.2    Vadhan-Raj, S.3
  • 73
    • 33748357134 scopus 로고    scopus 로고
    • Resveratrol-induced cyclooxygenase-2 facilitates p53-dependent apoptosis in human breast cancer cells [J]
    • Tang HY, Shih A, Cao HJ, et al. Resveratrol-induced cyclooxygenase-2 facilitates p53-dependent apoptosis in human breast cancer cells [J]. Mol Cancer Ther 2006, 5(8):2034-2042.
    • (2006) Mol Cancer Ther , vol.5 , Issue.8 , pp. 2034-2042
    • Tang, H.Y.1    Shih, A.2    Cao, H.J.3
  • 74
    • 32844461956 scopus 로고    scopus 로고
    • Resveratrol downregulates the constitutional activation of nuclear factor-κB in multiple myeloma cells, leading to suppression of proliferation and invasion, arrest of cell cycle, and induction of apoptosis [J]
    • Sun C, Hu Y, Liu X, et al. Resveratrol downregulates the constitutional activation of nuclear factor-κB in multiple myeloma cells, leading to suppression of proliferation and invasion, arrest of cell cycle, and induction of apoptosis [J]. Cancer Genet Cytogen 2006, 165(1):9-19.
    • (2006) Cancer Genet Cytogen , vol.165 , Issue.1 , pp. 9-19
    • Sun, C.1    Hu, Y.2    Liu, X.3
  • 75
    • 34247844379 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis in chemoresistant cancer cells via modulation of AMPK signaling pathway [J]
    • Hwang J, Kwak DW, LIin S, et al. Resveratrol induces apoptosis in chemoresistant cancer cells via modulation of AMPK signaling pathway [J]. Ann NY Acad Sci 2007, 1095(1):441-448.
    • (2007) Ann NY Acad Sci , vol.1095 , Issue.1 , pp. 441-448
    • Hwang, J.1    Kwak, D.W.2    LIin, S.3
  • 76
    • 35349009090 scopus 로고    scopus 로고
    • Resveratrol-induced apoptosis in human T-cell acute lymphoblastic leukaemia MOLT-4 cells [J]
    • Cecchinato V, Chiaramonte R, Nizzardo M, et al. Resveratrol-induced apoptosis in human T-cell acute lymphoblastic leukaemia MOLT-4 cells [J]. Biochem Pharmacol 2007, 74(11):1568-1574.
    • (2007) Biochem Pharmacol , vol.74 , Issue.11 , pp. 1568-1574
    • Cecchinato, V.1    Chiaramonte, R.2    Nizzardo, M.3
  • 77
    • 33947219035 scopus 로고    scopus 로고
    • Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines [J]
    • Benitez DA, Pozo-Guisado E, Alvarez-Barrientos A, et al. Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines [J]. J Androl 2007, 28(2):282-293.
    • (2007) J Androl , vol.28 , Issue.2 , pp. 282-293
    • Benitez, D.A.1    Pozo-Guisado, E.2    Alvarez-Barrientos, A.3
  • 78
    • 83655196879 scopus 로고    scopus 로고
    • An anticancer/cytotoxic activity of resveratrol is not hampered by its ability to induce the expression of the antioxidant/cytoprotective heme oxygenase-1 in RAW264.7 cells [J]
    • Sang Kil J, Son Y, Cheong YK, et al. An anticancer/cytotoxic activity of resveratrol is not hampered by its ability to induce the expression of the antioxidant/cytoprotective heme oxygenase-1 in RAW264.7 cells [J]. Biomed Pharmacother 2011, 1(2):146-152.
    • (2011) Biomed Pharmacother , vol.1 , Issue.2 , pp. 146-152
    • Sang Kil, J.1    Son, Y.2    Cheong, Y.K.3
  • 79
    • 75649091175 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo [J]
    • Bai Y, Mao Q, Qin J, et al. Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo [J]. Cancer Sci 2010, 101(2):488-493.
    • (2010) Cancer Sci , vol.101 , Issue.2 , pp. 488-493
    • Bai, Y.1    Mao, Q.2    Qin, J.3
  • 80
    • 79952661832 scopus 로고    scopus 로고
    • The grape antioxidant resveratrol for skin disorders: Promise, prospects, and challenges [J]
    • Ndiaye M, Philippe C, Mukhtar H, et al. The grape antioxidant resveratrol for skin disorders: Promise, prospects, and challenges [J]. Arch Biochem Biophys 2011, 508(2):164-170.
    • (2011) Arch Biochem Biophys , vol.508 , Issue.2 , pp. 164-170
    • Ndiaye, M.1    Philippe, C.2    Mukhtar, H.3
  • 81
    • 34848893955 scopus 로고    scopus 로고
    • Resveratrol suppresses prostate cancer progression in transgenic mice [J]
    • Harper CE, Patel BB, Wang J, et al. Resveratrol suppresses prostate cancer progression in transgenic mice [J]. Carcinogenesis 2007, 28(9):1946-1953.
    • (2007) Carcinogenesis , vol.28 , Issue.9 , pp. 1946-1953
    • Harper, C.E.1    Patel, B.B.2    Wang, J.3
  • 82
    • 33845663532 scopus 로고    scopus 로고
    • Resveratrol, a natural diphenol, reduces metastatic growth in an experimental cancer model [J]
    • Busquets S, Ametller E, Fuster G, et al. Resveratrol, a natural diphenol, reduces metastatic growth in an experimental cancer model [J]. Cancer Lett 2007, 245(1):144-148.
    • (2007) Cancer Lett , vol.245 , Issue.1 , pp. 144-148
    • Busquets, S.1    Ametller, E.2    Fuster, G.3
  • 83
    • 33746764998 scopus 로고    scopus 로고
    • 3H] trans-resveratrol in rat tissues following oral administration [J]
    • 3H] trans-resveratrol in rat tissues following oral administration [J]. Brit J Nutr 2006, 96(01):62-70.
    • (2006) Brit J Nutr , vol.96 , Issue.1 , pp. 62-70
    • El-mohsen, M.A.1    Bayele, H.2    Kuhnle, G.3
  • 84
    • 33748762484 scopus 로고    scopus 로고
    • Protective effect of resveratrol against oxygen-glucose deprivation in organotypic hippocampal slice cultures: involvement of PI3-K pathway [J]
    • Zamin LL, Dillenburg-Pilla P, Argenta Comiran R, et al. Protective effect of resveratrol against oxygen-glucose deprivation in organotypic hippocampal slice cultures: involvement of PI3-K pathway [J]. Neurobiol Dis 2006, 24(1):170-182.
    • (2006) Neurobiol Dis , vol.24 , Issue.1 , pp. 170-182
    • Zamin, L.L.1    Dillenburg-Pilla, P.2    Argenta Comiran, R.3
  • 85
    • 33947219035 scopus 로고    scopus 로고
    • Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines [J]
    • Benitez DA, Pozo Guisado E, Alvarez Barrientos A, et al. Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines [J]. J Androl 2007, 28(2):282-293.
    • (2007) J Androl , vol.28 , Issue.2 , pp. 282-293
    • Benitez, D.A.1    Pozo Guisado, E.2    Alvarez Barrientos, A.3
  • 86
    • 10344228747 scopus 로고    scopus 로고
    • Resveratrol inhibits nitric oxide and TNF-a production by lipopolysaccharide-activated microglia [J]
    • Bi XL, Yang JY, Dong YX, et al. Resveratrol inhibits nitric oxide and TNF-a production by lipopolysaccharide-activated microglia [J]. Int Immunopharmacol 2005, 5(1):185-193.
    • (2005) Int Immunopharmacol , vol.5 , Issue.1 , pp. 185-193
    • Bi, X.L.1    Yang, J.Y.2    Dong, Y.X.3
  • 87
    • 52649105485 scopus 로고    scopus 로고
    • Inhibitory effect of a novel resveratrol derivative on nitric oxide production in lipopolysaccharide-activated microglia [J]
    • Meng X, Chen G, Yang J, et al. Inhibitory effect of a novel resveratrol derivative on nitric oxide production in lipopolysaccharide-activated microglia [J]. Pharmazie 2008, 63(9):671-675.
    • (2008) Pharmazie , vol.63 , Issue.9 , pp. 671-675
    • Meng, X.1    Chen, G.2    Yang, J.3
  • 88
    • 45849091854 scopus 로고    scopus 로고
    • Effects of resveratrol and its derivatives on lipopolysaccharide-induced microglial activation and their structure-activity relationships [J]
    • Meng XL, Yang JY, Chen GL, et al. Effects of resveratrol and its derivatives on lipopolysaccharide-induced microglial activation and their structure-activity relationships [J]. Chem-Biol Interact 2008, 174(1):51-59.
    • (2008) Chem-Biol Interact , vol.174 , Issue.1 , pp. 51-59
    • Meng, X.L.1    Yang, J.Y.2    Chen, G.L.3
  • 89
    • 50949116213 scopus 로고    scopus 로고
    • RV09, a novel resveratrol analogue, inhibits NO and TNF-a production by LPS-activated microglia [J]
    • Meng XL, Yang JY, Chen GL, et al. RV09, a novel resveratrol analogue, inhibits NO and TNF-a production by LPS-activated microglia [J]. Int Immunopharmacol 2008, 8(8):1074-1082.
    • (2008) Int Immunopharmacol , vol.8 , Issue.8 , pp. 1074-1082
    • Meng, X.L.1    Yang, J.Y.2    Chen, G.L.3
  • 90
    • 24044472030 scopus 로고    scopus 로고
    • Trans-resveratrol, a red wine ingredient, inhibits voltage-activated potassium currents in rat hippocampal neurons [J]
    • Gao ZB, Hu GY Trans-resveratrol, a red wine ingredient, inhibits voltage-activated potassium currents in rat hippocampal neurons [J]. Brain Res 2005, 1056(1):68-75.
    • (2005) Brain Res , vol.1056 , Issue.1 , pp. 68-75
    • Gao, Z.B.1    Hu, G.Y.2
  • 91
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis [J]
    • Rosen DR, Siddique T, Patterson D, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis [J]. Nature 1993, 362(6415):59-62.
    • (1993) Nature , vol.362 , Issue.6415 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3
  • 92
    • 33846260752 scopus 로고    scopus 로고
    • Effect of resveratrol, a polyphenolic phytoalexin, on thermal hyperalgesia in a mouse model of diabetic neuropathic pain [J]
    • Sharma S, Kulkarni SK, Chopra K Effect of resveratrol, a polyphenolic phytoalexin, on thermal hyperalgesia in a mouse model of diabetic neuropathic pain [J]. Fund Clin Pharmacol 2007, 21(1):89-94.
    • (2007) Fund Clin Pharmacol , vol.21 , Issue.1 , pp. 89-94
    • Sharma, S.1    Kulkarni, S.K.2    Chopra, K.3
  • 93
    • 33847105184 scopus 로고    scopus 로고
    • Advances in the treatment of Parkinson's disease [J]
    • Singh N, Pillay V, Choonara YE Advances in the treatment of Parkinson's disease [J]. Prog Neurobiol 2007, 81(1):29-44.
    • (2007) Prog Neurobiol , vol.81 , Issue.1 , pp. 29-44
    • Singh, N.1    Pillay, V.2    Choonara, Y.E.3
  • 94
    • 33749557821 scopus 로고    scopus 로고
    • Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III [J]
    • Solans A, Zambrano A, Rodríguez M, et al. Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III [J]. Hum Mol Genet 2006, 15(20):3063-3081.
    • (2006) Hum Mol Genet , vol.15 , Issue.20 , pp. 3063-3081
    • Solans, A.1    Zambrano, A.2    Rodríguez, M.3
  • 95
    • 33845334891 scopus 로고    scopus 로고
    • Inhibitory activity of stilbenes on Alzheimer's β-amyloid fibrils in vitro [J]
    • Riviere C, Richard T, Quentin L, et al. Inhibitory activity of stilbenes on Alzheimer's β-amyloid fibrils in vitro [J]. Bioorg Med Chem 2007, 15(2):1160-1167.
    • (2007) Bioorg Med Chem , vol.15 , Issue.2 , pp. 1160-1167
    • Riviere, C.1    Richard, T.2    Quentin, L.3
  • 96
    • 27844497059 scopus 로고    scopus 로고
    • Resveratrol promotes clearance of Alzheimer's disease amyloid-β peptides [J]
    • Marambaud P, Zhao H, Davies P Resveratrol promotes clearance of Alzheimer's disease amyloid-β peptides [J]. J Biol Chem 2005, 280(45):37377-37382.
    • (2005) J Biol Chem , vol.280 , Issue.45 , pp. 37377-37382
    • Marambaud, P.1    Zhao, H.2    Davies, P.3
  • 97
    • 1942472491 scopus 로고    scopus 로고
    • Neuroprotective effects of resveratrol against β-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C [J]
    • Han YS, Zheng WH, Bastianetto S, et al. Neuroprotective effects of resveratrol against β-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C [J]. Brit J Pharmacol 2004, 141(6):997-1005.
    • (2004) Brit J Pharmacol , vol.141 , Issue.6 , pp. 997-1005
    • Han, Y.S.1    Zheng, W.H.2    Bastianetto, S.3
  • 98
    • 77950575506 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-β peptide metabolism [J]
    • Vingtdeux V, Giliberto L, Zhao H, et al. AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-β peptide metabolism [J]. J Biol Chem 2010, 285(12):9100-9113.
    • (2010) J Biol Chem , vol.285 , Issue.12 , pp. 9100-9113
    • Vingtdeux, V.1    Giliberto, L.2    Zhao, H.3
  • 99
    • 84892561930 scopus 로고    scopus 로고
    • Dietary resveratrol prevents Alzheimer's markers and increases life span in SAMP8 [J]
    • Porquet D, Casadesus G, Bayod S, et al. Dietary resveratrol prevents Alzheimer's markers and increases life span in SAMP8 [J]. Age 2012.
    • (2012) Age
    • Porquet, D.1    Casadesus, G.2    Bayod, S.3
  • 100
    • 56149119401 scopus 로고    scopus 로고
    • Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats [J]
    • Jin F, Wu Q, Lu YF, et al. Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats [J]. Eur J Pharmacol 2008, 600(1-3):78-82.
    • (2008) Eur J Pharmacol , vol.600 , Issue.1-3 , pp. 78-82
    • Jin, F.1    Wu, Q.2    Lu, Y.F.3
  • 101
    • 49849091089 scopus 로고    scopus 로고
    • Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice [J]
    • Blanchet J, Longpre F, Bureau G, et al. Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice [J]. Prog Neuro-Psychoph 2008, 32(5):1243-1250.
    • (2008) Prog Neuro-Psychoph , vol.32 , Issue.5 , pp. 1243-1250
    • Blanchet, J.1    Longpre, F.2    Bureau, G.3
  • 102
    • 33748310632 scopus 로고    scopus 로고
    • Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms [J]
    • Kumar P, Padi SSV, Naidu PS, et al. Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms [J]. Behav Pharmacol 2006, 17(5-6):485-492.
    • (2006) Behav Pharmacol , vol.17 , Issue.5-6 , pp. 485-492
    • Kumar, P.1    Padi, S.S.V.2    Naidu, P.S.3
  • 104
    • 77952674793 scopus 로고    scopus 로고
    • Anti-inflammatory activities of resveratrol in the brain: role of resveratrol in microglial activation [J]
    • Zhang F, Liu J, Shi JS Anti-inflammatory activities of resveratrol in the brain: role of resveratrol in microglial activation [J]. Eur J Pharmacol 2010, 636(1):1-7.
    • (2010) Eur J Pharmacol , vol.636 , Issue.1 , pp. 1-7
    • Zhang, F.1    Liu, J.2    Shi, J.S.3
  • 105
    • 31544456122 scopus 로고    scopus 로고
    • Protective effect of 1, 2, 4-benzenetriol on LPS-induced NO production by BV2 microglial cells [J]
    • Hou RCW, Chen YS, Chen CH, et al. Protective effect of 1, 2, 4-benzenetriol on LPS-induced NO production by BV2 microglial cells [J]. J Biomed Sci 2006, 13(1):89-99.
    • (2006) J Biomed Sci , vol.13 , Issue.1 , pp. 89-99
    • Hou, R.C.W.1    Chen, Y.S.2    Chen, C.H.3
  • 106
    • 58149518005 scopus 로고    scopus 로고
    • Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-[kappa] B pathways [J]
    • Jung WK, Ahn YW, Lee SH, et al. Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-[kappa] B pathways [J]. Food Chem Toxicol 2009, 47(2):410-417.
    • (2009) Food Chem Toxicol , vol.47 , Issue.2 , pp. 410-417
    • Jung, W.K.1    Ahn, Y.W.2    Lee, S.H.3
  • 107
    • 1642308134 scopus 로고    scopus 로고
    • Neurodegenerative diseases and oxidative stress [J]
    • Barnham KJ, Masters CL, Bush AI Neurodegenerative diseases and oxidative stress [J]. Nat Rev Drug Discov 2004, 3(3):205-214.
    • (2004) Nat Rev Drug Discov , vol.3 , Issue.3 , pp. 205-214
    • Barnham, K.J.1    Masters, C.L.2    Bush, A.I.3
  • 108
    • 33748750998 scopus 로고    scopus 로고
    • Dual effects of antioxidants in neurodegeneration: direct neuroprotection against oxidative stress and indirect protection via suppression of gliamediated inflammation [J]
    • Wang JY, Wen LL, Huang YN, et al. Dual effects of antioxidants in neurodegeneration: direct neuroprotection against oxidative stress and indirect protection via suppression of gliamediated inflammation [J]. Curr Pharm Design 2006, 12(27):3521-3533.
    • (2006) Curr Pharm Design , vol.12 , Issue.27 , pp. 3521-3533
    • Wang, J.Y.1    Wen, L.L.2    Huang, Y.N.3
  • 109
    • 36849092504 scopus 로고    scopus 로고
    • Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia [J]
    • Candelario-Jalil E, de Oliveira AC, Graf S, et al. Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia [J]. J Neuroinflamm 2007, 4(25):1-12.
    • (2007) J Neuroinflamm , vol.4 , Issue.25 , pp. 1-12
    • Candelario-Jalil, E.1    de Oliveira, A.C.2    Graf, S.3
  • 110
    • 0242662063 scopus 로고    scopus 로고
    • Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: effect on nitrosative and oxidative stress derived from microglial cells [J]
    • Lorenz P, Roychowdhury S, Engelmann M, et al. Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: effect on nitrosative and oxidative stress derived from microglial cells [J]. Nitric Oxide 2003, 9(2):64-76.
    • (2003) Nitric Oxide , vol.9 , Issue.2 , pp. 64-76
    • Lorenz, P.1    Roychowdhury, S.2    Engelmann, M.3
  • 111
    • 34447649377 scopus 로고    scopus 로고
    • Direct in vivo evidence of protective effects of grape seed procyanidin fractions and other antioxidants against ethanol-induced oxidative DNA damage in mouse brain cells [J]
    • Guo L, Wang LH, Sun B, et al. Direct in vivo evidence of protective effects of grape seed procyanidin fractions and other antioxidants against ethanol-induced oxidative DNA damage in mouse brain cells [J]. J Agric Food Chem 2007, 55(14):5881-5891.
    • (2007) J Agric Food Chem , vol.55 , Issue.14 , pp. 5881-5891
    • Guo, L.1    Wang, L.H.2    Sun, B.3
  • 112
    • 78650394881 scopus 로고    scopus 로고
    • Possible metabolic pathways of ethanol responsible for oxidative DNA damage in human peripheral lymphocytes [J]
    • Yan Y, Yang JY, Mou YH, et al. Possible metabolic pathways of ethanol responsible for oxidative DNA damage in human peripheral lymphocytes [J]. Alcohol Clin Exp Res 2011, 35(1):1-9.
    • (2011) Alcohol Clin Exp Res , vol.35 , Issue.1 , pp. 1-9
    • Yan, Y.1    Yang, J.Y.2    Mou, Y.H.3
  • 113
    • 49749101150 scopus 로고    scopus 로고
    • Oxidative DNA damage induced by ethanol in mouse peripheral leucocytes [J]
    • Guo L, Yang JY, Wu CF Oxidative DNA damage induced by ethanol in mouse peripheral leucocytes [J]. Basic Clin Pharmacol Toxicol 2008, 103(3):222-227.
    • (2008) Basic Clin Pharmacol Toxicol , vol.103 , Issue.3 , pp. 222-227
    • Guo, L.1    Yang, J.Y.2    Wu, C.F.3
  • 114
    • 84855242085 scopus 로고    scopus 로고
    • Differences in the activities of resveratrol and ascorbic acid in protection of ethanol-induced oxidative DNA damage in human peripheral lymphocytes [J]
    • Yan Y, Yang JY, Mou YH, et al. Differences in the activities of resveratrol and ascorbic acid in protection of ethanol-induced oxidative DNA damage in human peripheral lymphocytes [J]. Food Chem Toxicol 2012, 50(2):168-174.
    • (2012) Food Chem Toxicol , vol.50 , Issue.2 , pp. 168-174
    • Yan, Y.1    Yang, J.Y.2    Mou, Y.H.3
  • 115
    • 84863692899 scopus 로고    scopus 로고
    • Specific Conditions for Resveratrol Neuroprotection against Ethanol-Induced Toxicity [J]
    • Gonthier B, Allibe N, Cottet-Rousselle C, et al. Specific Conditions for Resveratrol Neuroprotection against Ethanol-Induced Toxicity [J]. J Toxicol 2012, 2012:973134.
    • (2012) J Toxicol , vol.2012 , pp. 973134
    • Gonthier, B.1    Allibe, N.2    Cottet-Rousselle, C.3
  • 116
    • 34447517642 scopus 로고    scopus 로고
    • Resveratrol inhibition of Propionibacterium acnes [J]
    • Docherty JJ, McEwen HA, Sweet TJ, et al. Resveratrol inhibition of Propionibacterium acnes [J]. J Antimicrob Chemother 2007, 59(6):1182-1184.
    • (2007) J Antimicrob Chemother , vol.59 , Issue.6 , pp. 1182-1184
    • Docherty, J.J.1    McEwen, H.A.2    Sweet, T.J.3
  • 117
    • 79953043473 scopus 로고    scopus 로고
    • Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy [J]
    • Morselli E, Maiuri M, Markaki M, et al. Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy [J]. Cell Death Dis 2010, 1(1):e10.
    • (2010) Cell Death Dis , vol.1 , Issue.1
    • Morselli, E.1    Maiuri, M.2    Markaki, M.3
  • 118
    • 79960117900 scopus 로고    scopus 로고
    • Promise of resveratrol for easing status epilepticus and epilepsy [J]
    • Shetty AK Promise of resveratrol for easing status epilepticus and epilepsy [J]. Pharmacol Therapeut 2011, 131(3):269-286.
    • (2011) Pharmacol Therapeut , vol.131 , Issue.3 , pp. 269-286
    • Shetty, A.K.1
  • 119
    • 0037248470 scopus 로고    scopus 로고
    • Absorption of three wine-related polyphenols in three different matrices by healthy subjects [J]
    • Goldberg D, Yan J, Soleas G Absorption of three wine-related polyphenols in three different matrices by healthy subjects [J]. Clin Biochem 2003, 36(1):79-87.
    • (2003) Clin Biochem , vol.36 , Issue.1 , pp. 79-87
    • Goldberg, D.1    Yan, J.2    Soleas, G.3
  • 120
    • 77953353711 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics and tolerability of trans-resveratrol 2000mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects [J]
    • La PC, Voduc N, Zhang G, et al. Steady-state pharmacokinetics and tolerability of trans-resveratrol 2000mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects [J]. Clin Pharmacokinet 2010, 49(7):449-454.
    • (2010) Clin Pharmacokinet , vol.49 , Issue.7 , pp. 449-454
    • La, P.C.1    Voduc, N.2    Zhang, G.3
  • 121
    • 77956412951 scopus 로고    scopus 로고
    • Resveratrol modulates drug and carcinogen-metabolizing enzymes in a healthy volunteer study [J]
    • Chow H, Garland L, Hsu C, et al. Resveratrol modulates drug and carcinogen-metabolizing enzymes in a healthy volunteer study [J]. Cancer Prev Res 2010, 3(9):1168-1175.
    • (2010) Cancer Prev Res , vol.3 , Issue.9 , pp. 1168-1175
    • Chow, H.1    Garland, L.2    Hsu, C.3
  • 123
    • 79951683262 scopus 로고    scopus 로고
    • Effects of resveratrol and other wine polyphenols on vascular function: an update [J]
    • Gresele P, Cerletti C, Guglielmini G, et al. Effects of resveratrol and other wine polyphenols on vascular function: an update [J]. J Nutr Biochem 2011, 22(3):201-211.
    • (2011) J Nutr Biochem , vol.22 , Issue.3 , pp. 201-211
    • Gresele, P.1    Cerletti, C.2    Guglielmini, G.3
  • 124
    • 0037816232 scopus 로고    scopus 로고
    • Effect of low doses of ethanol on platelet function in long-life abstainers and moderate wine drinkers [J]
    • Miceli M, Alberti L, Bennardini F, et al. Effect of low doses of ethanol on platelet function in long-life abstainers and moderate wine drinkers [J]. Life Sci 2003, 73(12):1557-1566.
    • (2003) Life Sci , vol.73 , Issue.12 , pp. 1557-1566
    • Miceli, M.1    Alberti, L.2    Bennardini, F.3
  • 125
    • 84863328591 scopus 로고    scopus 로고
    • The journey of resveratrol from yeast to human [J]
    • Timmers S, Auwerx J, Schrauwen P The journey of resveratrol from yeast to human [J]. Aging 2012, 4(3):1-13.
    • (2012) Aging , vol.4 , Issue.3 , pp. 1-13
    • Timmers, S.1    Auwerx, J.2    Schrauwen, P.3
  • 126
    • 33947528355 scopus 로고    scopus 로고
    • Quantitation of trans-resveratrol and detection of its metabolites in human plasma and urine by high performance liquid chromatography [J]
    • Boocock D, Patel K, Faust G, et al. Quantitation of trans-resveratrol and detection of its metabolites in human plasma and urine by high performance liquid chromatography [J]. J Chromatogr B, Analyt Technol Biomed Life Sci 2007, 848(2):182-187.
    • (2007) J Chromatogr B, Analyt Technol Biomed Life Sci , vol.848 , Issue.2 , pp. 182-187
    • Boocock, D.1    Patel, K.2    Faust, G.3
  • 127
    • 67649999248 scopus 로고    scopus 로고
    • Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers [J]
    • Almeida L, Vazda SM, Falcao A, et al. Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers [J]. Mol Nutr Food Res 2009, 53(1):7-15.
    • (2009) Mol Nutr Food Res , vol.53 , Issue.1 , pp. 7-15
    • Almeida, L.1    Vazda, S.M.2    Falcao, A.3
  • 128
    • 71449113221 scopus 로고    scopus 로고
    • Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects. [J]
    • Nunes T, Almeida L, Rocha J, et al. Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects. [J]. J Clin Pharmacol 2009, 49(12):1477-1482.
    • (2009) J Clin Pharmacol , vol.49 , Issue.12 , pp. 1477-1482
    • Nunes, T.1    Almeida, L.2    Rocha, J.3
  • 129
    • 20344401340 scopus 로고    scopus 로고
    • Bioavailability of trans-resveratrol from red wine in humans [J]
    • Vitaglione P, Sforza S, Galaverna G, et al. Bioavailability of trans-resveratrol from red wine in humans [J]. Mol Nutr Food Res 2005, 49(5):495-504.
    • (2005) Mol Nutr Food Res , vol.49 , Issue.5 , pp. 495-504
    • Vitaglione, P.1    Sforza, S.2    Galaverna, G.3
  • 130
    • 78549288940 scopus 로고    scopus 로고
    • Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis [J]
    • Brown V, Patel K, Viskaduraki M, et al. Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis [J]. Cancer Res 2010, 70(22):9003-9011.
    • (2010) Cancer Res , vol.70 , Issue.22 , pp. 9003-9011
    • Brown, V.1    Patel, K.2    Viskaduraki, M.3
  • 131
    • 1242336775 scopus 로고    scopus 로고
    • Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice [J]
    • Meng X, Maliakal P, Lu H, et al. Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice [J]. J Agric Food Chem 2004, 52(4):935-942.
    • (2004) J Agric Food Chem , vol.52 , Issue.4 , pp. 935-942
    • Meng, X.1    Maliakal, P.2    Lu, H.3
  • 132
    • 77957355158 scopus 로고    scopus 로고
    • Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients [J]
    • Patel K, Brown V, Jones D, et al. Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients [J]. Cancer Res 2010, 70(19):7392-7399.
    • (2010) Cancer Res , vol.70 , Issue.19 , pp. 7392-7399
    • Patel, K.1    Brown, V.2    Jones, D.3
  • 133
    • 75049085079 scopus 로고    scopus 로고
    • Matrix effects on the bioavailability of resveratrol in humans. [J]
    • Ortuño J, Covas MI, Farre M, et al. Matrix effects on the bioavailability of resveratrol in humans. [J]. Food Chem 2010, 120(4):1123-1130.
    • (2010) Food Chem , vol.120 , Issue.4 , pp. 1123-1130
    • Ortuño, J.1    Covas, M.I.2    Farre, M.3
  • 134
    • 9444296057 scopus 로고    scopus 로고
    • High absorption but very low bioavailability of oral resveratrol in humans [J]
    • Walle T, Hsieh F, DeLegge M, et al. High absorption but very low bioavailability of oral resveratrol in humans [J]. Drug Metab Dispos 2004, 32(12):1377-1382.
    • (2004) Drug Metab Dispos , vol.32 , Issue.12 , pp. 1377-1382
    • Walle, T.1    Hsieh, F.2    DeLegge, M.3
  • 135
    • 51049085099 scopus 로고    scopus 로고
    • Resveratrol, at concentrations attainable with moderate wine consumption, stimulates human platelet nitric oxide production. [J]
    • Gresele P, Pignatelli P, Guglielmini G, et al. Resveratrol, at concentrations attainable with moderate wine consumption, stimulates human platelet nitric oxide production. [J]. J Nutr 2008, 138(9):1602-1608.
    • (2008) J Nutr , vol.138 , Issue.9 , pp. 1602-1608
    • Gresele, P.1    Pignatelli, P.2    Guglielmini, G.3
  • 136
    • 18844372768 scopus 로고    scopus 로고
    • Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry [J]
    • Urpi SM, Jauregui O, Lamuela RR, et al. Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry [J]. Anal Chem 2005, 77(10):3149-3155.
    • (2005) Anal Chem , vol.77 , Issue.10 , pp. 3149-3155
    • Urpi, S.M.1    Jauregui, O.2    Lamuela, R.R.3
  • 137
    • 79955675928 scopus 로고    scopus 로고
    • A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal. [J]
    • Ghanim H, Sia C, Korzeniewski K, et al. A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal. [J]. J Clin Endocrinol Metab 2011, 96(5):1409-1414.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.5 , pp. 1409-1414
    • Ghanim, H.1    Sia, C.2    Korzeniewski, K.3
  • 138
    • 77953032816 scopus 로고    scopus 로고
    • Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation [J]
    • Kennedy D, Wightman E, Reay J, et al. Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation [J]. Am J Clin Nutr 2010, 91(6):1590-1597.
    • (2010) Am J Clin Nutr , vol.91 , Issue.6 , pp. 1590-1597
    • Kennedy, D.1    Wightman, E.2    Reay, J.3
  • 139
    • 84950170835 scopus 로고    scopus 로고
    • Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure [J]
    • Wong RH, PR H, JD B Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure [J]. Nutr Metab Cardiovasc Dis 2011, 21(11):851-856.
    • (2011) Nutr Metab Cardiovasc Dis , vol.21 , Issue.11 , pp. 851-856
    • Wong, R.H.1    PR, H.2    JD, B.3
  • 140
    • 79958099432 scopus 로고    scopus 로고
    • Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer [J]
    • Nguyen A, Martinez M, Stamos M, et al. Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer [J]. Cancer Manag Res 2009, 1:25-37.
    • (2009) Cancer Manag Res , vol.1 , pp. 25-37
    • Nguyen, A.1    Martinez, M.2    Stamos, M.3
  • 141
    • 78851472303 scopus 로고    scopus 로고
    • Clinical trials of resveratrol [J]
    • Patel KR, Scott E, Brown VA, et al. Clinical trials of resveratrol [J]. Ann NY Acad Sci 2011, 1215:161-169.
    • (2011) Ann NY Acad Sci , vol.1215 , pp. 161-169
    • Patel, K.R.1    Scott, E.2    Brown, V.A.3
  • 142
    • 76649084868 scopus 로고    scopus 로고
    • Resveratrol/SRT-501 [J]
    • Elliott P, Walpole S, Morelli L, et al. Resveratrol/SRT-501 [J]. Drugs Fut 2009, 34(4):291-295.
    • (2009) Drugs Fut , vol.34 , Issue.4 , pp. 291-295
    • Elliott, P.1    Walpole, S.2    Morelli, L.3
  • 143
    • 80052910300 scopus 로고    scopus 로고
    • Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients [J]
    • Brasnyo P, Molnar G, Mohas M, et al. Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients [J]. Br J Nutr 2011, 106(3):383-389.
    • (2011) Br J Nutr , vol.106 , Issue.3 , pp. 383-389
    • Brasnyo, P.1    Molnar, G.2    Mohas, M.3
  • 144
    • 80455143206 scopus 로고    scopus 로고
    • Calorie Restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. [J]
    • Timmers S, Konings E, Bilet L, et al. Calorie Restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. [J]. Cell Metab 2011, 14(5):612-622.
    • (2011) Cell Metab , vol.14 , Issue.5 , pp. 612-622
    • Timmers, S.1    Konings, E.2    Bilet, L.3
  • 145
    • 84860131782 scopus 로고    scopus 로고
    • Pilot study of resveratrol in older adults with impaired glucose tolerance. [J]
    • Crandall J, Oram V, Trandafirescu G, et al. Pilot study of resveratrol in older adults with impaired glucose tolerance. [J]. J Gerontol A-Biol 2012, 67(12):1307-1312.
    • (2012) J Gerontol A-Biol , vol.67 , Issue.12 , pp. 1307-1312
    • Crandall, J.1    Oram, V.2    Trandafirescu, G.3


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