메뉴 건너뛰기




Volumn 3, Issue 9, 2010, Pages 1168-1175

Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; BILIRUBIN GLUCURONIDE; BUSPIRONE; CAFFEINE; CYTOCHROME P450 1A2; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DEXTROMETHORPHAN; GLUCURONOSYLTRANSFERASE 1A1; GLUTATHIONE TRANSFERASE; LOSARTAN; RESVERATROL;

EID: 77956412951     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-09-0155     Document Type: Article
Times cited : (268)

References (34)
  • 2
    • 0031839670 scopus 로고    scopus 로고
    • Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the "French paradox"?
    • Kopp P. Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the "French paradox"? Eur J Endocrinol 1998;138:619-20.
    • (1998) Eur J Endocrinol , vol.138 , pp. 619-620
    • Kopp, P.1
  • 3
    • 33646068410 scopus 로고    scopus 로고
    • Resveratrol as a chemopreventive agent: A promising molecule for fighting cancer
    • Delmas D, Lancon A, Colin D, Jannin B, Latruffe N. Resveratrol as a chemopreventive agent: a promising molecule for fighting cancer. Curr Drug Targets 2006;7:423-42.
    • (2006) Curr Drug Targets , vol.7 , pp. 423-442
    • Delmas, D.1    Lancon, A.2    Colin, D.3    Jannin, B.4    Latruffe, N.5
  • 4
    • 22844450866 scopus 로고    scopus 로고
    • Resveratrol as an anticancer nutrient: Molecular basis, open questions and promises
    • Signorelli P, Ghidoni R. Resveratrol as an anticancer nutrient: molecular basis, open questions and promises. J Nutr Biochem 2005;16:449-66.
    • (2005) J Nutr Biochem , vol.16 , pp. 449-466
    • Signorelli, P.1    Ghidoni, R.2
  • 7
    • 67650297506 scopus 로고    scopus 로고
    • Cancer prevention and treatment with resveratrol: From rodent studies to clinical trials
    • Bishayee A. Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials. Cancer Prev Res 2009;2:409-18.
    • (2009) Cancer Prev Res , vol.2 , pp. 409-418
    • Bishayee, A.1
  • 8
    • 0032535055 scopus 로고    scopus 로고
    • Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor
    • Ciolino HP, Daschner PJ, Yeh GC. Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor. Cancer Res 1998;58:5707-12.
    • (1998) Cancer Res , vol.58 , pp. 5707-5712
    • Ciolino, H.P.1    Daschner, P.J.2    Yeh, G.C.3
  • 9
    • 11844306055 scopus 로고    scopus 로고
    • Cell-based high-throughput bioassays to assess induction and inhibition of CYP1A enzymes
    • Yueh MF, Kawahara M, Raucy J. Cell-based high-throughput bioassays to assess induction and inhibition of CYP1A enzymes. Toxicol In Vitro 2005;19:275-87.
    • (2005) Toxicol in Vitro , vol.19 , pp. 275-287
    • Yueh, M.F.1    Kawahara, M.2    Raucy, J.3
  • 10
    • 0042700218 scopus 로고    scopus 로고
    • Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene
    • Revel A, Raanani H, Younglai E, et al. Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[a]pyrene. J Appl Toxicol 2003;23:255-61.
    • (2003) J Appl Toxicol , vol.23 , pp. 255-261
    • Revel, A.1    Raanani, H.2    Younglai, E.3
  • 11
    • 0035313982 scopus 로고    scopus 로고
    • Lung carcinogenesis: Resveratrol modulates the expression of genes involved in the metabolism of pah in human bronchial epithelial cells
    • Mollerup S, Ovrebo S, Haugen A. Lung carcinogenesis: resveratrol modulates the expression of genes involved in the metabolism of PAH in human bronchial epithelial cells. Int J Cancer 2001;92:18-25. (Pubitemid 32187027)
    • (2001) International Journal of Cancer , vol.92 , Issue.1 , pp. 18-25
    • Mollerup, S.1    Ovrebo, S.2    Haugen, A.3
  • 12
    • 6444222048 scopus 로고    scopus 로고
    • Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells
    • Chen ZH, Hurh YJ, Na HK, et al. Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells. Carcinogenesis 2004;25:2005-13.
    • (2004) Carcinogenesis , vol.25 , pp. 2005-2013
    • Chen, Z.H.1    Hurh, Y.J.2    Na, H.K.3
  • 13
    • 0035976379 scopus 로고    scopus 로고
    • Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components
    • Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91.
    • (2001) Toxicol Lett , vol.125 , pp. 83-91
    • Piver, B.1    Berthou, F.2    Dreano, Y.3    Lucas, D.4
  • 14
    • 0035076024 scopus 로고    scopus 로고
    • Effect of trans-resveratrol on 7-benzyloxy-4-trifluoromethylcoumarin O-dealkylation catalyzed by human recombinant CYP3A4 and CYP3A5
    • Chang TK, Yeung RK. Effect of trans-resveratrol on 7-benzyloxy-4- trifluoromethylcoumarin O-dealkylation catalyzed by human recombinant CYP3A4 and CYP3A5. Can J Physiol Pharmacol 2001;79:220-6.
    • (2001) Can J Physiol Pharmacol , vol.79 , pp. 220-226
    • Chang, T.K.1    Yeung, R.K.2
  • 15
    • 0037436851 scopus 로고    scopus 로고
    • Antioxidant activity of melatonin in Chinese hamster ovarian cells: Changes in cellular proliferation and differentiation
    • Sainz RM, Mayo JC, Tan DX, Lopez-Burillo S, Natarajan M, Reiter RJ. Antioxidant activity of melatonin in Chinese hamster ovarian cells: changes in cellular proliferation and differentiation. Biochem Biophys Res Commun 2003;302:625-34.
    • (2003) Biochem Biophys Res Commun , vol.302 , pp. 625-634
    • Sainz, R.M.1    Mayo, J.C.2    Tan, D.X.3    Lopez-Burillo, S.4    Natarajan, M.5    Reiter, R.J.6
  • 16
    • 3042641988 scopus 로고    scopus 로고
    • Alteration in phase I and II enzyme activities and polycyclic aromatic hydrocarbons-DNA adduct formation by plant phenolics in mouse epidermis
    • Szaefer H, Cichocki M, Brauze D, Baer-Dubowska W. Alteration in phase I and II enzyme activities and polycyclic aromatic hydrocarbons-DNA adduct formation by plant phenolics in mouse epidermis. Nutr Cancer 2004;48:70-7.
    • (2004) Nutr Cancer , vol.48 , pp. 70-77
    • Szaefer, H.1    Cichocki, M.2    Brauze, D.3    Baer-Dubowska, W.4
  • 17
    • 0037294150 scopus 로고    scopus 로고
    • Mechanism-based in vitro screening of potential cancer chemopreventive agents
    • Gerhauser C, Klimo K, Heiss E, et al. Mechanism-based in vitro screening of potential cancer chemopreventive agents. Mutat Res 2003;523-524:163-72.
    • (2003) Mutat Res , vol.523-524 , pp. 163-172
    • Gerhauser, C.1    Klimo, K.2    Heiss, E.3
  • 18
    • 0037402970 scopus 로고    scopus 로고
    • Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes
    • Yen GC, Duh PD, Lin CW. Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes. Free Radic Res 2003;37:509-14.
    • (2003) Free Radic Res , vol.37 , pp. 509-514
    • Yen, G.C.1    Duh, P.D.2    Lin, C.W.3
  • 19
    • 0038548118 scopus 로고    scopus 로고
    • The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes
    • Christensen M, Andersson K, Dalen P, et al. The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes. Clin Pharmacol Ther 2003;73:517-28.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 517-528
    • Christensen, M.1    Andersson, K.2    Dalen, P.3
  • 20
    • 0021336171 scopus 로고
    • Quantitative determination of dextromethorphan and three metabolites in urine by reverse-phase high-performance liquid chromatography
    • Park YH, Kullberg MP, Hinsvark ON. Quantitative determination of dextromethorphan and three metabolites in urine by reverse-phase high-performance liquid chromatography. J Pharm Sci 1984;73:24-9.
    • (1984) J Pharm Sci , vol.73 , pp. 24-29
    • Park, Y.H.1    Kullberg, M.P.2    Hinsvark, O.N.3
  • 21
    • 0027227583 scopus 로고
    • High-performance liquid chromatography determination of dextromethorphan and dextrorphan for oxidation phenotyping by fluorescence and ultraviolet detection
    • Lam YWF, Rodriguez SY. High-performance liquid chromatography determination of dextromethorphan and dextrorphan for oxidation phenotyping by fluorescence and ultraviolet detection. Ther Drug Monit 1993;15:300-4.
    • (1993) Ther Drug Monit , vol.15 , pp. 300-304
    • Lam, Y.W.F.1    Rodriguez, S.Y.2
  • 22
    • 0030970607 scopus 로고    scopus 로고
    • An improved method for the simultaneous determination of losartan and its major metabolite, EXP3174, in human plasma and urine by high-performance liquid chromatography with fluorescence detection
    • Ritter MA, Furtek CI, Lo MW. An improved method for the simultaneous determination of losartan and its major metabolite, EXP3174, in human plasma and urine by high-performance liquid chromatography with fluorescence detection. J Pharm Biomed Anal 1997;15:1021-9.
    • (1997) J Pharm Biomed Anal , vol.15 , pp. 1021-1029
    • Ritter, M.A.1    Furtek, C.I.2    Lo, M.W.3
  • 24
    • 33947528355 scopus 로고    scopus 로고
    • Quantitation of trans-resveratrol and detection of its metabolites in human plasma and urine by high performance liquid chromatography
    • Boocock D, Patel KR, Faust GES, et al. Quantitation of trans-resveratrol and detection of its metabolites in human plasma and urine by high performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 2007;848:182-7.
    • (2007) J Chromatogr B Analyt Technol Biomed Life Sci , vol.848 , pp. 182-187
    • Boocock, D.1    Patel, K.R.2    Faust, G.E.S.3
  • 27
    • 34250901592 scopus 로고    scopus 로고
    • Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent
    • Boocock DJ, Faust GE, Patel KR, et al. Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent. Cancer Epidemiol Biomarkers Prev 2007;16:1246-52.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 1246-1252
    • Boocock, D.J.1    Faust, G.E.2    Patel, K.R.3
  • 28
    • 0035930896 scopus 로고    scopus 로고
    • Benzo[a]pyrene-induced toxicity: Paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels
    • Uno S, Dalton TP, Shertzer HG, et al. Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels. Biochem Biophys Res Commun 2001;289:1049-56.
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 1049-1056
    • Uno, S.1    Dalton, T.P.2    Shertzer, H.G.3
  • 29
    • 2142695286 scopus 로고    scopus 로고
    • Oral exposure to benzo[a]pyrene in the mouse: Detoxication by inducible cytochrome P450 is more important than metabolic activation
    • Uno S, Dalton TP, Derkenne S, et al. Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation. Mol Pharmacol 2004;65:1225-37.
    • (2004) Mol Pharmacol , vol.65 , pp. 1225-1237
    • Uno, S.1    Dalton, T.P.2    Derkenne, S.3
  • 30
    • 19944434201 scopus 로고    scopus 로고
    • CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
    • Jin Y, Desta Z, Stearns V, et al. CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J Natl Cancer Inst 2005;97:30-9.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 30-39
    • Jin, Y.1    Desta, Z.2    Stearns, V.3
  • 31
    • 33847034287 scopus 로고    scopus 로고
    • The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen
    • Goetz MP, Knox SK, Suman VJ, et al. The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen. Breast Cancer Res Treat 2007;101:113-21.
    • (2007) Breast Cancer Res Treat , vol.101 , pp. 113-121
    • Goetz, M.P.1    Knox, S.K.2    Suman, V.J.3
  • 32
    • 67549122883 scopus 로고    scopus 로고
    • Cruciferous vegetable feeding alters UGT1A1 activity: Diet- and genotype-dependent changes in serum bilirubin in a controlled feeding trial
    • Navarro SL, Peterson S, Chen C, et al. Cruciferous vegetable feeding alters UGT1A1 activity: diet- and genotype-dependent changes in serum bilirubin in a controlled feeding trial. Cancer Prev Res 2009;2:345-52.
    • (2009) Cancer Prev Res , vol.2 , pp. 345-352
    • Navarro, S.L.1    Peterson, S.2    Chen, C.3
  • 33
    • 0028867826 scopus 로고
    • The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
    • Bosma PJ, Chowdhury JR, Bakker C, et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 1995;333:1171-5.
    • (1995) N Engl J Med , vol.333 , pp. 1171-1175
    • Bosma, P.J.1    Chowdhury, J.R.2    Bakker, C.3
  • 34
    • 34548103204 scopus 로고    scopus 로고
    • Modulation of human glutathione S-transferases by polyphenon E intervention
    • Chow HH, Hakim IA, Vining DR, et al. Modulation of human glutathione S-transferases by polyphenon E intervention. Cancer Epidemiol Biomarkers Prev 2007;16:1662-6.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 1662-1666
    • Chow, H.H.1    Hakim, I.A.2    Vining, D.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.