메뉴 건너뛰기




Volumn 87, Issue 2, 2013, Pages 269-283

FadD3 is an acyl-CoA synthetase that initiates catabolism of cholesterol rings C and D in actinobacteria

Author keywords

[No Author keywords available]

Indexed keywords

3A ALPHA H 4ALPHA (3' PROPANOATE) 7A BETA METHYLHEXAHYDRO 1,5 INDANEDIONE; ADENOSINE TRIPHOSPHATE; COENZYME A; FADD3 PROTEIN; LONG CHAIN FATTY ACID COENZYME A LIGASE; UNCLASSIFIED DRUG;

EID: 84872370910     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12095     Document Type: Article
Times cited : (70)

References (62)
  • 1
    • 60249099423 scopus 로고    scopus 로고
    • Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis
    • Arora, P., Goyal, A., Natarajan, V.T., Rajakumara, E., Verma, P., Gupta, R., etal. (2009) Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis. Nat Chem Biol 5: 166-173.
    • (2009) Nat Chem Biol , vol.5 , pp. 166-173
    • Arora, P.1    Goyal, A.2    Natarajan, V.T.3    Rajakumara, E.4    Verma, P.5    Gupta, R.6
  • 2
    • 0026631359 scopus 로고
    • Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases
    • Babbitt, P.C., Kenyon, G.L., Martin, B.M., Charest, H., Slyvestre, M., Scholten, J.D., etal. (1992) Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases. Biochemistry 31: 5594-5604.
    • (1992) Biochemistry , vol.31 , pp. 5594-5604
    • Babbitt, P.C.1    Kenyon, G.L.2    Martin, B.M.3    Charest, H.4    Slyvestre, M.5    Scholten, J.D.6
  • 3
    • 0000404096 scopus 로고
    • The growth of micro-organisms in relation to their energy supply
    • Bauchop, T., and Elsden, S.R. (1960) The growth of micro-organisms in relation to their energy supply. J Gen Microbiol 23: 457-469.
    • (1960) J Gen Microbiol , vol.23 , pp. 457-469
    • Bauchop, T.1    Elsden, S.R.2
  • 4
    • 3442889456 scopus 로고    scopus 로고
    • On the mechanism of action of the antifungal agent propionate
    • Brock, M., and Buckel, W. (2004) On the mechanism of action of the antifungal agent propionate. Eur J Biochem 271: 3227-3241.
    • (2004) Eur J Biochem , vol.271 , pp. 3227-3241
    • Brock, M.1    Buckel, W.2
  • 5
    • 0036774642 scopus 로고    scopus 로고
    • Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv
    • Camus, J.C., Pryor, M.J., Médigue, C., and Cole, S.T. (2002) Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Microbiology 148: 2967-2973.
    • (2002) Microbiology , vol.148 , pp. 2967-2973
    • Camus, J.C.1    Pryor, M.J.2    Médigue, C.3    Cole, S.T.4
  • 6
    • 65649132303 scopus 로고    scopus 로고
    • Characterization of 3-ketosteroid 9α-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis
    • Capyk, J.K., D'Angelo, I., Strynadka, N.C., and Eltis, L.D. (2009) Characterization of 3-ketosteroid 9α-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis. J Biol Chem 284: 9937-9946.
    • (2009) J Biol Chem , vol.284 , pp. 9937-9946
    • Capyk, J.K.1    D'Angelo, I.2    Strynadka, N.C.3    Eltis, L.D.4
  • 7
    • 81755171443 scopus 로고    scopus 로고
    • Activity of 3-ketosteroid 9α-hydroxylase (KshAB) indicates cholesterol side chain and ring degradation occur simultaneously in Mycobacterium tuberculosis
    • Capyk, J.K., Casabon, I., Gruninger, R., Strynadka, N.C., and Eltis, L.D. (2011) Activity of 3-ketosteroid 9α-hydroxylase (KshAB) indicates cholesterol side chain and ring degradation occur simultaneously in Mycobacterium tuberculosis. J Biol Chem 286: 40717-40724.
    • (2011) J Biol Chem , vol.286 , pp. 40717-40724
    • Capyk, J.K.1    Casabon, I.2    Gruninger, R.3    Strynadka, N.C.4    Eltis, L.D.5
  • 9
    • 0031469570 scopus 로고    scopus 로고
    • Acyl-adenylate motif of the acyl-adenylate/thioester-forming enzyme superfamily: a site-directed mutagenesis study with the Pseudomonas sp. strain CBS3 4-chlorobenzoate:coenzyme A ligase
    • Chang, K.H., Xiang, H., and Dunaway-Mariano, D. (1997) Acyl-adenylate motif of the acyl-adenylate/thioester-forming enzyme superfamily: a site-directed mutagenesis study with the Pseudomonas sp. strain CBS3 4-chlorobenzoate:coenzyme A ligase. Biochemistry 36: 15650-15659.
    • (1997) Biochemistry , vol.36 , pp. 15650-15659
    • Chang, K.H.1    Xiang, H.2    Dunaway-Mariano, D.3
  • 10
    • 84868614745 scopus 로고    scopus 로고
    • Genomic and transcriptomic studies of an RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine)-degrading actinobacterium
    • Chen, H.P., Zhu, S.H., Casabon, I., Hallam, S.J., Crocker, F.H., Mohn, W.W., etal. (2012) Genomic and transcriptomic studies of an RDX (hexahydro-1, 3, 5-trinitro-1, 3, 5-triazine)-degrading actinobacterium. Appl Environ Microbiol 78: 7798-7800.
    • (2012) Appl Environ Microbiol , vol.78 , pp. 7798-7800
    • Chen, H.P.1    Zhu, S.H.2    Casabon, I.3    Hallam, S.J.4    Crocker, F.H.5    Mohn, W.W.6
  • 11
    • 0032508046 scopus 로고    scopus 로고
    • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
    • Cole, S.T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., etal. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537-544.
    • (1998) Nature , vol.393 , pp. 537-544
    • Cole, S.T.1    Brosch, R.2    Parkhill, J.3    Garnier, T.4    Churcher, C.5    Harris, D.6
  • 13
    • 77954575769 scopus 로고    scopus 로고
    • A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism
    • Dresen, C., Lin, L.Y., D'Angelo, I., Tocheva, E.I., Strynadka, N., and Eltis, L.D. (2010) A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism. J Biol Chem 285: 22264-22275.
    • (2010) J Biol Chem , vol.285 , pp. 22264-22275
    • Dresen, C.1    Lin, L.Y.2    D'Angelo, I.3    Tocheva, E.I.4    Strynadka, N.5    Eltis, L.D.6
  • 14
    • 0035910144 scopus 로고    scopus 로고
    • Unmarked gene deletion mutagenesis of kstD, encoding 3-ketosteroid Δ1-dehydrogenase, in Rhodococcus erythropolis SQ1 using sacB as counter-selectable marker
    • van der Geize, R., Hessels, G.I., van Gerwen, R., van der Meijden, P., and Dijkhuizen, L. (2001) Unmarked gene deletion mutagenesis of kstD, encoding 3-ketosteroid Δ1-dehydrogenase, in Rhodococcus erythropolis SQ1 using sacB as counter-selectable marker. FEMS Microbiol Lett 205: 197-202.
    • (2001) FEMS Microbiol Lett , vol.205 , pp. 197-202
    • van der Geize, R.1    van Hessels, G.I.2    van der Gerwen, R.3    Meijden, P.4    Dijkhuizen, L.5
  • 15
    • 33846904705 scopus 로고    scopus 로고
    • A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages
    • van der Geize, R., Yam, K., Heuser, T., Wilbrink, M.H., Hara, H., Anderton, M.C., etal. (2007) A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages. Proc Natl Acad Sci USA 104: 1947-1952.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1947-1952
    • van der Geize, R.1    Yam, K.2    Heuser, T.3    Wilbrink, M.H.4    Hara, H.5    Anderton, M.C.6
  • 16
    • 80052330722 scopus 로고    scopus 로고
    • The steroid catabolic pathway of the intracellular pathogen Rhodococcus equi is important for pathogenesis and a target for vaccine development
    • van der Geize, R., Grommen, A.W.F., Hessels, G.I., Jacobs, A.A.C., and Dijkhuizen, L. (2011) The steroid catabolic pathway of the intracellular pathogen Rhodococcus equi is important for pathogenesis and a target for vaccine development. PLoS Pathog 7: e1002181.
    • (2011) PLoS Pathog , vol.7
    • van der Geize, R.1    Grommen, A.W.F.2    Hessels, G.I.3    Jacobs, A.A.C.4    Dijkhuizen, L.5
  • 17
    • 0028226896 scopus 로고
    • Analysis of core sequences in the D-Phe activating domain of the multifunctional peptide synthetase TycA by site-directed mutagenesis
    • Gocht, M., and Marahiel, M.A. (1994) Analysis of core sequences in the D-Phe activating domain of the multifunctional peptide synthetase TycA by site-directed mutagenesis. J Bacteriol 176: 2654-2662.
    • (1994) J Bacteriol , vol.176 , pp. 2654-2662
    • Gocht, M.1    Marahiel, M.A.2
  • 18
    • 80053459692 scopus 로고    scopus 로고
    • High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism
    • Griffin, J.E., Gawronski, J.D., DeJesus, M.A., Ioerger, T.R., Akerley, B.J., and Sassetti, C.M. (2011) High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism. PLoS Pathog 7: e1002251.
    • (2011) PLoS Pathog , vol.7
    • Griffin, J.E.1    Gawronski, J.D.2    DeJesus, M.A.3    Ioerger, T.R.4    Akerley, B.J.5    Sassetti, C.M.6
  • 20
    • 0016888730 scopus 로고
    • Fatty acid activation: specificity, localization, and function
    • Groot, P.H.E., Scholte, H.R., and Hulsmann, W.C. (1976) Fatty acid activation: specificity, localization, and function. Adv Lipid Res 14: 75-126.
    • (1976) Adv Lipid Res , vol.14 , pp. 75-126
    • Groot, P.H.E.1    Scholte, H.R.2    Hulsmann, W.C.3
  • 21
    • 0017775191 scopus 로고
    • Microbiological degradation of bile acids. Metabolites formed from 3-(3aα-hexahydro-7aβ-methyl-1,5-dioxoindan-4α-yl) propionic acid by Streptomyces rubescens
    • Hashimoto, S., and Hayakawa, S. (1977) Microbiological degradation of bile acids. Metabolites formed from 3-(3aα-hexahydro-7aβ-methyl-1, 5-dioxoindan-4α-yl) propionic acid by Streptomyces rubescens. Biochem J 164: 715-726.
    • (1977) Biochem J , vol.164 , pp. 715-726
    • Hashimoto, S.1    Hayakawa, S.2
  • 22
    • 77957671514 scopus 로고    scopus 로고
    • Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survival
    • Homolka, S., Niemann, S., Russell, D.G., and Rohde, K.H. (2010) Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survival. PLoS Pathog 6: e1000988.
    • (2010) PLoS Pathog , vol.6
    • Homolka, S.1    Niemann, S.2    Russell, D.G.3    Rohde, K.H.4
  • 23
    • 25144452553 scopus 로고    scopus 로고
    • Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441
    • Horinouchi, M., Hayashi, T., Koshino, H., Kurita, T., and Kudo, T. (2005) Identification of 9, 17-dioxo-1, 2, 3, 4, 10, 19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2, 4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441. Appl Environ Microbiol 71: 5275-5281.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 5275-5281
    • Horinouchi, M.1    Hayashi, T.2    Koshino, H.3    Kurita, T.4    Kudo, T.5
  • 24
    • 33748051066 scopus 로고    scopus 로고
    • ORF18-disrupted mutant of Comamonas testosteroni TA441 accumulates significant amounts of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid and its derivatives after incubation with steroids
    • Horinouchi, M., Hayashi, T., Koshino, H., and Kudo, T. (2006) ORF18-disrupted mutant of Comamonas testosteroni TA441 accumulates significant amounts of 9, 17-dioxo-1, 2, 3, 4, 10, 19-hexanorandrostan-5-oic acid and its derivatives after incubation with steroids. J Steroid Biochem Mol Biol 101: 78-84.
    • (2006) J Steroid Biochem Mol Biol , vol.101 , pp. 78-84
    • Horinouchi, M.1    Hayashi, T.2    Koshino, H.3    Kudo, T.4
  • 25
    • 0037133231 scopus 로고    scopus 로고
    • Characterization of the propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica: residue Lys592 is required for propionyl-AMP synthesis
    • Horswill, A.R., and Escalante-Semerena, J.C. (2002) Characterization of the propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica: residue Lys592 is required for propionyl-AMP synthesis. Biochemistry 41: 2379-2387.
    • (2002) Biochemistry , vol.41 , pp. 2379-2387
    • Horswill, A.R.1    Escalante-Semerena, J.C.2
  • 26
    • 72949108894 scopus 로고    scopus 로고
    • 3-Ketosteroid 9α-hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis
    • Hu, Y., van der Geize, R., Besra, G.S., Gurcha, S.S., Liu, A., Rohde, M., etal. (2010) 3-Ketosteroid 9α-hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis. Mol Microbiol 75: 107-121.
    • (2010) Mol Microbiol , vol.75 , pp. 107-121
    • Hu, Y.1    van der Geize, R.2    Besra, G.S.3    Gurcha, S.S.4    Liu, A.5    Rohde, M.6
  • 27
    • 78449258062 scopus 로고    scopus 로고
    • Functional redundancy of steroid C26-monooxygenase activity in Mycobacterium tuberculosis revealed by biochemical and genetic analyses
    • Johnston, J.B., Ouellet, H., and Ortiz de Montellano, P.R. (2010) Functional redundancy of steroid C26-monooxygenase activity in Mycobacterium tuberculosis revealed by biochemical and genetic analyses. J Biol Chem 285: 36352-36360.
    • (2010) J Biol Chem , vol.285 , pp. 36352-36360
    • Johnston, J.B.1    Ouellet, H.2    Ortiz de Montellano, P.R.3
  • 28
    • 0343193205 scopus 로고    scopus 로고
    • The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies
    • Jung, J.W., An, J.H., Na, K.B., Kim, Y.S., and Lee, W. (2000) The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies. Protein Sci 9: 1294-1303.
    • (2000) Protein Sci , vol.9 , pp. 1294-1303
    • Jung, J.W.1    An, J.H.2    Na, K.B.3    Kim, Y.S.4    Lee, W.5
  • 29
    • 0035711194 scopus 로고    scopus 로고
    • Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency
    • Kapust, R.B., Tözsér, J., Fox, J.D., Anderson, D.E., Cherry, S., Copeland, T.D., and Waugh, D.S. (2001) Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency. Protein Eng 14: 993-1000.
    • (2001) Protein Eng , vol.14 , pp. 993-1000
    • Kapust, R.B.1    Tözsér, J.2    Fox, J.D.3    Anderson, D.E.4    Cherry, S.5    Copeland, T.D.6    Waugh, D.S.7
  • 30
    • 77952370884 scopus 로고    scopus 로고
    • Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2
    • Kendall, S.L., Burgess, P., Balhana, R., Withers, M., ten Bokum, A., Lott, J.S., etal. (2010) Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2. Microbiology 156: 1362-1371.
    • (2010) Microbiology , vol.156 , pp. 1362-1371
    • Kendall, S.L.1    Burgess, P.2    Balhana, R.3    Withers, M.4    ten Bokum, A.5    Lott, J.S.6
  • 31
    • 77956930778 scopus 로고    scopus 로고
    • Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism
    • Kim, M.J., Wainwright, H.C., Locketz, M., Bekker, L.G., Walther, G.B., Dittrich, C., etal. (2010) Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism. EMBO Mol Med 2: 258-274.
    • (2010) EMBO Mol Med , vol.2 , pp. 258-274
    • Kim, M.J.1    Wainwright, H.C.2    Locketz, M.3    Bekker, L.G.4    Walther, G.B.5    Dittrich, C.6
  • 32
    • 73649123859 scopus 로고    scopus 로고
    • Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism
    • Lack, N.A., Yam, K.C., Lowe, E.D., Horsman, G.P., Owen, R.L., Sim, E., and Eltis, L.D. (2010) Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism. J Biol Chem 285: 434-443.
    • (2010) J Biol Chem , vol.285 , pp. 434-443
    • Lack, N.A.1    Yam, K.C.2    Lowe, E.D.3    Horsman, G.P.4    Owen, R.L.5    Sim, E.6    Eltis, L.D.7
  • 33
    • 0014086905 scopus 로고
    • Mechanisms of steroid oxidation by microorganisms. XII. Metabolism of hexahydroindanpropionic acid derivatives
    • Lee, S.S., and Sih, C.J. (1967) Mechanisms of steroid oxidation by microorganisms. XII. Metabolism of hexahydroindanpropionic acid derivatives. Biochemistry 6: 1395-1403.
    • (1967) Biochemistry , vol.6 , pp. 1395-1403
    • Lee, S.S.1    Sih, C.J.2
  • 34
    • 0342794213 scopus 로고    scopus 로고
    • Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
    • McKinney, J.D., Höner zu Bentrup, K., Muñoz-Elías, E.J., Miczak, A., Chen, B., Chan, W.T., etal. (2000) Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature 406: 735-738.
    • (2000) Nature , vol.406 , pp. 735-738
    • McKinney, J.D.1    Höner zu Bentrup, K.2    Muñoz-Elías, E.J.3    Miczak, A.4    Chen, B.5    Chan, W.T.6
  • 35
    • 33746191929 scopus 로고    scopus 로고
    • The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse
    • McLeod, M.P., Warren, R.L., Hsiao, W.W., Araki, N., Myhre, M., Fernandes, C., etal. (2006) The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse. Proc Natl Acad Sci USA 103: 15582-15587.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15582-15587
    • McLeod, M.P.1    Warren, R.L.2    Hsiao, W.W.3    Araki, N.4    Myhre, M.5    Fernandes, C.6
  • 36
    • 0029042175 scopus 로고
    • The binding of propionyl-CoA and carboxymethyl-CoA to Escherichia coli citrate synthase
    • Man, W.J., Li, Y., O'Connor, C.D., and Wilton, D.C. (1995) The binding of propionyl-CoA and carboxymethyl-CoA to Escherichia coli citrate synthase. Biochim Biophys Acta 1250: 69-75.
    • (1995) Biochim Biophys Acta , vol.1250 , pp. 69-75
    • Man, W.J.1    Li, Y.2    O'Connor, C.D.3    Wilton, D.C.4
  • 37
    • 0025218652 scopus 로고
    • Catabolism of methylperhydroindanedione propionate by Rhodococcus equi: evidence of a MEPHIP-reductase activity
    • Miclo, A., and Germain, P. (1990) Catabolism of methylperhydroindanedione propionate by Rhodococcus equi: evidence of a MEPHIP-reductase activity. Appl Microbiol Biotechnol 32: 594-599.
    • (1990) Appl Microbiol Biotechnol , vol.32 , pp. 594-599
    • Miclo, A.1    Germain, P.2
  • 40
    • 4644233997 scopus 로고    scopus 로고
    • Isolation and characterization of a rolling-circle-type plasmid from Rhodococcus erythropolis and application of the plasmid to multiple-recombinant-protein expression
    • Nakashima, N., and Tamura, T. (2004) Isolation and characterization of a rolling-circle-type plasmid from Rhodococcus erythropolis and application of the plasmid to multiple-recombinant-protein expression. Appl Environ Microbiol 70: 5557-5568.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 5557-5568
    • Nakashima, N.1    Tamura, T.2
  • 41
    • 73449085857 scopus 로고    scopus 로고
    • A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol
    • Nesbitt, N.M., Yang, X., Fontán, P., Kolesnikova, I., Smith, I., Sampson, N.S., and Dubnau, E. (2010) A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol. Infect Immun 78: 275-282.
    • (2010) Infect Immun , vol.78 , pp. 275-282
    • Nesbitt, N.M.1    Yang, X.2    Fontán, P.3    Kolesnikova, I.4    Smith, I.5    Sampson, N.S.6    Dubnau, E.7
  • 42
    • 80755138435 scopus 로고    scopus 로고
    • Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis
    • Ouellet, H., Johnston, J.B., and Ortiz de Montellano, P.R. (2011) Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis. Trends Microbiol 19: 530-539.
    • (2011) Trends Microbiol , vol.19 , pp. 530-539
    • Ouellet, H.1    Johnston, J.B.2    Ortiz de Montellano, P.R.3
  • 43
    • 41949119272 scopus 로고    scopus 로고
    • Mycobacterial persistence requires the utilization of host cholesterol
    • Pandey, A.K., and Sassetti, C.M. (2008) Mycobacterial persistence requires the utilization of host cholesterol. Proc Natl Acad Sci USA 105: 4376-4380.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 4376-4380
    • Pandey, A.K.1    Sassetti, C.M.2
  • 44
    • 2442643102 scopus 로고    scopus 로고
    • Toxicity caused by hydroxycinnamoyl-coenzyme A thioester accumulation in mutants of Acinetobacter sp. strain ADP1
    • Parke, D., and Ornston, L.N. (2004) Toxicity caused by hydroxycinnamoyl-coenzyme A thioester accumulation in mutants of Acinetobacter sp. strain ADP1. Appl Environ Microbiol 70: 2974-2983.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 2974-2983
    • Parke, D.1    Ornston, L.N.2
  • 45
    • 20444419421 scopus 로고    scopus 로고
    • Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages
    • Rengarajan, J., Bloom, B.R., and Rubin, E.J. (2005) Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages. Proc Natl Acad Sci USA 102: 8327-8332.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8327-8332
    • Rengarajan, J.1    Bloom, B.R.2    Rubin, E.J.3
  • 46
    • 75149194492 scopus 로고    scopus 로고
    • In Salmonella enterica, 2-methylcitrate blocks gluconeogenesis
    • Rocco, C.J., and Escalante-Semerena, J.C. (2010) In Salmonella enterica, 2-methylcitrate blocks gluconeogenesis. J Bacteriol 192: 771-778.
    • (2010) J Bacteriol , vol.192 , pp. 771-778
    • Rocco, C.J.1    Escalante-Semerena, J.C.2
  • 47
    • 33845683474 scopus 로고    scopus 로고
    • Who puts the tubercle in tuberculosis?
    • Russell, D.G. (2007) Who puts the tubercle in tuberculosis? Nat Rev Microbiol 5: 39-47.
    • (2007) Nat Rev Microbiol , vol.5 , pp. 39-47
    • Russell, D.G.1
  • 50
    • 0242268400 scopus 로고    scopus 로고
    • Genetic requirements for mycobacterial survival during infection
    • Sassetti, C.M., and Rubin, E.J. (2003) Genetic requirements for mycobacterial survival during infection. Proc Natl Acad Sci USA 100: 12989-12994.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12989-12994
    • Sassetti, C.M.1    Rubin, E.J.2
  • 51
    • 0028289983 scopus 로고
    • Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicum
    • Schäfer, A., Tauch, A., Jäger, W., Kalinowski, J., Thierbach, G., and Pühler, A. (1994) Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicum. Gene 145: 69-73.
    • (1994) Gene , vol.145 , pp. 69-73
    • Schäfer, A.1    Tauch, A.2    Jäger, W.3    Kalinowski, J.4    Thierbach, G.5    Pühler, A.6
  • 52
    • 0043142536 scopus 로고    scopus 로고
    • Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment
    • Schnappinger, D., Ehrt, S., Voskuil, M.I., Liu, Y., Mangan, J.A., Monahan, I.M., etal. (2003) Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J Exp Med 198: 693-704.
    • (2003) J Exp Med , vol.198 , pp. 693-704
    • Schnappinger, D.1    Ehrt, S.2    Voskuil, M.I.3    Liu, Y.4    Mangan, J.A.5    Monahan, I.M.6
  • 53
    • 0029128756 scopus 로고
    • A novel transformation of polychlorinated biphenyls by Rhodococcus sp. strain RHA1
    • Seto, M., Kimbara, K., Shimura, M., Hatta, T., Fukuda, M., and Yano, K. (1995) A novel transformation of polychlorinated biphenyls by Rhodococcus sp. strain RHA1. Appl Environ Microbiol 61: 3353-3358.
    • (1995) Appl Environ Microbiol , vol.61 , pp. 3353-3358
    • Seto, M.1    Kimbara, K.2    Shimura, M.3    Hatta, T.4    Fukuda, M.5    Yano, K.6
  • 54
    • 0347457075 scopus 로고    scopus 로고
    • Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
    • Starai, V.J., Celic, I., Cole, R.N., Boeke, J.D., and Escalante-Semerena, J.C. (2002) Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine. Science 298: 2390-2392.
    • (2002) Science , vol.298 , pp. 2390-2392
    • Starai, V.J.1    Celic, I.2    Cole, R.N.3    Boeke, J.D.4    Escalante-Semerena, J.C.5
  • 55
    • 84870712589 scopus 로고    scopus 로고
    • Two transporters essential for the reassimilation of novel cholate metabolites by Rhodococcus jostii RHA1
    • doi: 10.1128/JB.01167-12.
    • Swain, K., Casabon, I., Eltis, L.D., and Mohn, W.W. (2012) Two transporters essential for the reassimilation of novel cholate metabolites by Rhodococcus jostii RHA1. J Bacteriol doi: 10.1128/JB.01167-12.
    • (2012) J Bacteriol
    • Swain, K.1    Casabon, I.2    Eltis, L.D.3    Mohn, W.W.4
  • 56
    • 83755168972 scopus 로고    scopus 로고
    • Pathway profiling in Mycobacterium tuberculosis: elucidation of a cholesterol-derived catabolite and the enzymes that catalyze its metabolism
    • Thomas, S.T., VanderVen, B.C., Sherman, D.R., Russell, D.G., and Sampson, N.S. (2011) Pathway profiling in Mycobacterium tuberculosis: elucidation of a cholesterol-derived catabolite and the enzymes that catalyze its metabolism. J Biol Chem 286: 43668-43678.
    • (2011) J Biol Chem , vol.286 , pp. 43668-43678
    • Thomas, S.T.1    VanderVen, B.C.2    Sherman, D.R.3    Russell, D.G.4    Sampson, N.S.5
  • 57
    • 1842577641 scopus 로고    scopus 로고
    • Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria
    • Trivedi, O.A., Arora, P., Sridharan, V., Tickoo, R., Mohanty, D., and Gokhale, R.S. (2004) Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria. Nature 428: 441-445.
    • (2004) Nature , vol.428 , pp. 441-445
    • Trivedi, O.A.1    Arora, P.2    Sridharan, V.3    Tickoo, R.4    Mohanty, D.5    Gokhale, R.S.6
  • 58
    • 79955103273 scopus 로고    scopus 로고
    • WHO Geneva, Switzerland: World Health Organization -.
    • WHO (2011) Global Tuberculosis Control: WHO Report 2011. Geneva, Switzerland: World Health Organization, pp. 3-73.
    • (2011) Global Tuberculosis Control: WHO Report 2011 , pp. 3-73
  • 59
    • 79960100287 scopus 로고    scopus 로고
    • FadD19 of Rhodococcus rhodochrous DSM43269: a steroid-CoA ligase essential for degradation of C24-branched sterol side chains
    • Wilbrink, M.H., Petrusma, M., Dijkhuizen, L., and van der Geize, R. (2011) FadD19 of Rhodococcus rhodochrous DSM43269: a steroid-CoA ligase essential for degradation of C24-branched sterol side chains. Appl Environ Microbiol 77: 4455-4464.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 4455-4464
    • Wilbrink, M.H.1    Petrusma, M.2    van der Dijkhuizen, L.3    Geize, R.4
  • 60
    • 79959791094 scopus 로고    scopus 로고
    • The reversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMP
    • Xu, H., Hegde, S.S., and Blanchard, J.S. (2011) The reversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMP. Biochemistry 50: 5883-5892.
    • (2011) Biochemistry , vol.50 , pp. 5883-5892
    • Xu, H.1    Hegde, S.S.2    Blanchard, J.S.3
  • 61
    • 63449105307 scopus 로고    scopus 로고
    • Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis
    • Yam, K.C., D'Angelo, I., Kalscheuer, R., Zhu, H., Wang, J.X., Snieckus, V., etal. (2009) Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis. PLoS Pathog 5: e1000344.
    • (2009) PLoS Pathog , vol.5
    • Yam, K.C.1    D'Angelo, I.2    Kalscheuer, R.3    Zhu, H.4    Wang, J.X.5    Snieckus, V.6
  • 62
    • 34547731308 scopus 로고    scopus 로고
    • Rv1106c from Mycobacterium tuberculosis is a 3β-hydroxysteroid dehydrogenase
    • Yang, X., Dubnau, E., Smith, I., and Sampson, N.S. (2007) Rv1106c from Mycobacterium tuberculosis is a 3β-hydroxysteroid dehydrogenase. Biochemistry 46: 9058-9067.
    • (2007) Biochemistry , vol.46 , pp. 9058-9067
    • Yang, X.1    Dubnau, E.2    Smith, I.3    Sampson, N.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.