Surfactants and block copolymers in drug delivery

Colloids in Drug Delivery

Volumn , Issue , 2016, Pages 1-54

  Misra, Ambikanandan ^a   Florence, Kiruba ^a   Lalan, Manisha ^a   Shah, Tapan ^a  

^a M S UNIVERSITY OF BARODA   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BLOCK COPOLYMERS;

DRUG DELIVERY;

EID: 84872353119     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (196)

1. Afsaneh, L., John, S., and Glen, S. K., 2002. Poly(ethylene oxide)-block-poly(l-amino acid) micelles for drug delivery. Adv. Drug Deliv. Rev., 54, 169-190.
2. Aguire, J. M., Bagan, J. V., Rodriguez, C., Jimenez, Y., Martinez, C. R., Diaz de Rojas, F., and Ponte, A., 2004. Efficacy of mometasone furoate microemulsion in the treatment of erosive, ulcerative oral lichen planus:Pilot study. J. Oral Pathol. Med., 33(7), 381-385.
3. Alexandris, P., 2000. Amphiphilic Block Copolymers: Self Assembly and Applications. Amsterdam, Elsevier.
4. Alving, C. R., 1982. Therapeutic potential of liposomes as carriers in leishmaniasis, malaria and vaccines. In Targeting of Drugs, G. Gregoriadis, J. Senior, and A. Trouet (Eds), p. 285. New York, Plenum Press.
5. Ameller, T., Marsaud, V., Legrand, P., et al., 2003. Polyester-poly(ethylene glycol) nanoparticles loaded with the pure anti estrogen RU 58668: Physicochemical and opsonization properties. Pharm. Res., 20, 1063-1070.
6. Anacker, E. W., Geer, R. D., and Eylar E. H., 1971. Dependence of micelle aggregation number on polar head structure. I. Light scattering by aqueous solutions of decylammonium salts and related surfactants. J. Phys. Chem., 75(3), 369-374.
7. Armes, S. P., Butun, V., and Billingham, N. C., 1997. Synthesis and aqueous solution properties of novel hydrophilic- hydrophilic block copolymers based on tertiary amine methacrylates. Chem. Commun., 671-672.
8. Armes, S. P., Lee, A. S., Gast, A. P., and Butun, V., 1999. Characterizing the structure of pH dependent polyelectrolyte block copolymer micelles. Macromolecules, 32, 302-310.
9. Arnarson, T. and Elworthy, P. H., 1981. Effects of structural variations on non-ionic surfactants on micellar properties and solubilization: Surfactants containing very long hydrocarbon chains. J. Pharm. Pharmacol., 33, 141.
10. Arunothayanun, P. and Pirayavaraporn, C., 2004. Self-emulsifying drug delivery systems (SEDDS) for ritonavir oral solution. International Conference on AIDS (15th, Bangkok, Thailand). Abstract no. A10030.
11. Atef, E. and Belmonte, A. A., 2008. Formulation and in vitro and in vivo characterization of a phenytoin selfemulsifying drug delivery system (SEDDS). Eur. J. Pharm. Sci., 35(4), 257-263.
12. Attama, A. A. and Nzekwe, I. T., 2003. The use of solid self-emulsifying systems in the delivery of diclofenac. Int. J. Pharm., 262(1-2), 23-28.
13. Attwood, D. and Florence, A. T., 1983. Surfactant Systems-Their Chemistry, Pharmacy and Biology, pp. 72-117. New York, Chapman & Hall.
14. Atyabi, F., Khodaverdi, E., and Dinarvand, R., 2007. Temperature modulated drug permeation through liquid crystal embedded cellulose membranes. Int. J. Pharm., 339(1-2), 213-221.
15. Bajpai, A. K. and Choubey, J., 2006. Design of gelatin nanoparticles as swelling controlled delivery system for chloroquin phosphate. J. Mater. Sci. Mater. Med., 17(4), 345-358.
16. Bakker-Wounderberg, I. A., Storm, G., and Woodle, M. C., 1994. Liposomes in treatment of infections. J. Drug Target, 2, 363-371.
17. Balmbra R. R., Clunie, J. S., Corkill, J. M., et al., 1962. Effect of temperature on the micelle size of a homogeneous non-ionic detergent. Trans. Faraday Soc., 58, 1661.
18. Barker, M. and Vincent, B., 1984. Micellar solutions and microemulsions containing polystyrene/poly(ethylene oxide) AB block copolymers. Colloids Surf., 8, 297-314.
19. Barrat, G. M., Tenu, J. P., Yapo, A., and Petit, J. F., 1986. Preparation and characterization of liposomes containing mannosylated phospholipids capable of targetting drugs to macrophages. Biochim. Biophys. Acta, 862, 153-164.
20. Berne, B. J. and Pecora, R., 2000. Dynamic Light Scattering with Applications to Chemistry, Biology and Physics. New York, Dover Publications.
21. Bilensoy, E., Dogan, A. L., Sen, M., and Hincal, A. A., 2007. Complexation behavior of antiestrogen drug tamoxifen citrate with natural and modified cyclodextrins. J. Inclusion Phenom. Macrocyclic Chem., 57, 651-655.
22. Borges, O., Borchard, G., Verhoef, J. C., et al., 2005. Preparation of coated nanoparticles for a new mucosal vaccine delivery system. Int. J. Pharm., 299(1-2), 268-276.
23. Boudad, H., Legrand, P., LeBas, G., Cheron, M., Duchene, D., and Ponchel, G., 2001. Combined hydroxyopropyl- beta-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir. Int. J. Pharm., 218, 113-124.
24. Boyd, B. J., 2005. Colloidal drug delivery, Drug delivery report, 63-70.
25. Boyd, B. J., 2008. Past and future evolution in colloidal drug delivery systems. Expert Opin. Drug Deliv., 5(1), 69-85.
26. Boyd, B. J. and Whittaker, D. V., 2006. Lyotropic liquid crystalline phases formed from glycerate surfactants as sustained release drug delivery systems. Int. J. Pharm., 309(1-2), 218-226.
27. Brignole, C., Marimpietri, D., Pagnan, G., et al., 2005. Neuroblastoma targeting by c-myb-selective antisense oligonucleotides entrapped in anti GD2 immunoliposome: Immune cell mediated anti tumour activities. Cancer Lett., 228, 181-186.
28. Burchard, W., 1983. Static and dynamic light scattering from branched polymers and biopolymers. Adv. Polym. Sci., 48, 1-124.
29. Burke, S., Shen, H., and Eisenberg, A., 2001. Multiple vesicular morphologies from block copolymers in solution. Macromol. Symp., 175, 273-283.
30. Caralgia, M., Addeo, R., Costanzo, R., et al., 2006. Phase II study of temozolomide plus pegylated liposomal doxorubicin in the treatment of brain metastases from solid tumours. Cancer Chemother. Pharmacol., 57, 34-39.
31. Chae, G. S. and Lee, J. S., 2005. Enhancement of the stability of BCNU using self-emulsifying drug delivery systems (SEDDS) and in vitro antitumor activity of self-emulsified BCNU-loaded PLGA wafer. Int. J. Pharm., 301(1-2), 6-14.
32. Charman, S. A. and Charman, W. N., 1992. Self-emulsifying drug delivery systems: Formulation and biopharmaceutic evaluation of an investigational lipophilic compound. Pharm. Res., 9(1), 87-93.
33. Chausson, M. and Fluchere, A.-S., 2008. Block copolymers of the type poly(caprolactone)-b-poly(ethylene oxide) for the preparation and stabilization of nanoemulsions. Int. J. Pharm., 362(1-2), 153-162.
34. Chiappetta, D. A. and Sosnik, A., 2007. Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability and bioavailability of drugs. Eur. J. Pharm. Biopharm., 66, 303-317.
35. Cilek, A., Celebi, N., and Tirnaksiz, F., 2006. Lecithin based microemulsion of a peptide for oral administration, preparation, characterization and physical stability of the formulation. Drug Deliv., 13(1), 19-24.
36. Cirpanh, Y., Bilensoy, E., Calis, S., and Hincal, A. A., 2006. Camphothecin inclusion complexes with natural and modified beta cyclodextrins. In: Proceedings of the 33rd Annual Meeting and Exhibition on Controlled Release Society, Vienna, July 22-26, pp. 988-989.
37. Cirpanh, Y., Bilensoy, E., Calis, S., and Hincal, A. A., 2007. Development of camphothecin loaded nanoparticles from amphiphilic beta cyclodextrin derivatives. Paper presented at the Pharmaceutical Sciences World Congress PSWC, Amsterdam, April 22-25.
38. Coester, C., Nayyar, P., and Samuel, J., 2006. In vitro uptake of gelatin nanoparticles by murine dendritic cells and their intracellular localization. Eur. J. Pharm. Biopharm., 62(3), 306-314.
39. Constantinides, P. P., 1995. Lipid microemulsion for improving drugs dissolution and oral absorption: Physical and biopharmaceutical aspects. Pharm. Res., 12, 1561-1572.
40. Corkill, J. M., Goodman, J. F., Harrold, S. P., 1964. Thermodynamics of micellization of non-ionic detergents. Trans. Faraday Soc., 60, 202.
41. Couvreur, P. and Vauthier, C., 1991. Poly alkyl cyanoacrylate nanoparticles as drug carriers: Present state and future perspective. J. Control. Release, 17, 187-198.
42. Daoud, M. and Cotton, J. P., 1982. Star-shaped polymers: A model for the conformation and its concentration dependence. J. Phys. (Fr), 43, 531-538.
43. Di Stefano, A., Carafa, M., Sozio, P., et al., 2004. Evaluation of rat striatal l-dopa and DA concentration after intraperitoneal administration of l-dopa pro drugs in liposomal formulations. J. Control. Release, 99, 293-300.
44. Doddoli, C., Ghez, O., Barlesi, F., D'journo, B., Robitail, S., Thomas, P., and Clerc, T., 2005. In vitro and in vivo methotrexate disposition in alveolar macrophages: Comparison of pharmacokinetic parameters of two formulations. Int. J. Pharm., 297, 180-189.
45. Dominguez, A., Fernandez, A., Gonzalez, N., et al., 1997. Determination of critical micelle concentration of some surfactants by three techniques. J. Chem. Educ., 74(10), 1227-1231.
46. Douglas, S. J., Davis, S. S., and Illum, L., 1987. Nanoparticles in drug delivery. Crit. Rev. Ther. Drug Carrier Syst., 3, 233-261.
47. Eastman, S. J., Tousignant, J. D., Lukason, M. J., et al., 1997. Optimization of formulations and conditions for the aerosol delivery of functional cationic lipid: DNA complexes. Hum. Gene Ther., 8, 313-322.
48. Eisenberg, A. and Yu, K. E., 1998. Bilayer morphologies of self-assembled crew-cut aggregates of amphiphilic PS-b-PEO diblock copolymers in solution. Macromolecules, 31, 3509-3518.
49. Fessi, H., Puisieux, F., Devissaguet, J. P., et al., 1989. Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int. J. Pharm. 55, R1-R4.
50. Florence, A. T., 1993. Non-ionic surfactant vesicles preparation and characterisation. In: Liposome Technology, G. Gregoradis (Ed.), 2nd ed., Vol. 2, pp. 157-176. Boca Raton, FL, CRC Press.
51. Forster, S. and Plantenberg, T., 2002. From self-organizing polymers to nanohybrid and biomaterials. Angew. Chem. Int., 41, 688-714.
52. Fujimoto, Y., Okuhata, Y., Tyngi, S., Namba, Y., and Oku, N., 2000. Magnetic resonance lymphography of profounded lymph nodes with liposomal gadolinium-diethylenetriamine penta acetic acid. Biol. Pharm. Bull., 23, 97-100.
53. Ganta, S., Paxton, J. W., Baguley, B. C., and Garg, S., 2008. Pharmacokinetics and pharmacodynamics of chlorambucil delivered in parenteral emulsion. Int. J. Pharm., 360(1-2), 115-121.
54. Gaucher Genevieve, Dufresne Marie-Helene, Sant Vinayak, P., et al., 2005. Block copolymer micelles:Preparation, characterization and application in drug delivery. J. Control. Release, 109, 169-188.
55. Godin, B. and Touitou, E., 2003. Ethosomes: New prospects in transdermal delivery. Crit. Rev. Ther. Drug Carrier Syst., 20, 63-102.
56. Gradishar, W. J., 2005. The future of breast cancer: The role of prognostic factors. Breast Cancer Res. Treat., 89, S17-S26.
57. Granger, C. E., Feliz, C. P., Parrot-Lopez, H., and Langlois, B. R., 2000. Fluorine containing beta cyclodextrin:A new class of ampbiphilic carriers. Tetrahedron Lett., 41, 9257-9260.
58. Gregoriadis, G., Bacon, A., Caparros-Wanderley, W., and McCormack, B., 2002. A role for liposomes in genetic vaccinatin. Vaccine, 20, B1-B9.
59. Gursoy, N. and Benita, S., 2004. Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. Biomed. Pharmacother., 58(3), 173-182.
60. Hadjichristidis, N., Pispas, S., and Floudas, G. A., 2003. Block Copolymers: Synthetic Strategies, Physical Properties, and Applications. New York, Wiley.
61. Han, I., Kim, M., and Kim, J., 2004. Enhanced transfollicular delivery of adriamycin with a liposome and iontophoresis. Exp. Dermatol., 13, 86-92.
62. Hede, K., 2005. Blocking cancer with RNA interference moves towards the clinic. J. Natl. Cancer Inst., 97, 626-628.
63. Hioka, N., Chowdhary, R. K., Chansarkar, N., et al., 2002. Studies of a benzoporphyrin derivative with Pluronics. Can. J. Chem., 80, 1321-1326.
64. Hofheinz, R. D., Gnad-Vogt, S. U., Beyer, U., and Hochchaus, A., 2005. Liposomal encapsulated anti cancer drugs. Anti Cancer Drugs, 16, 691-707.
65. Holmberg, E. G., Reuer, Q. R., Geisert, E. E., et al., 1994. Delivery of plasmid DNA to glial cells using pH sensitive liposomes. Biochem. Biophys. Res. Commun., 201(2), 888-893.
66. Hong, J. Y., Kim, J. K., Song, Y. K., et al., 2006. A new self-emulsifying formulation of itraconazole with improved dissolution and oral absorption. J. Control. Release, 110(2), 332-338.
67. Hurtrez, G., 1992. Study of PS-PEO and PEO-PS-PEO block copolymers (in French). PhD Thesis. University Haute Alsace, France.
68. Hyung Park, J., Kwon, S., Lee, M., et al., 2006. Self-assembled nanoparticles based on glycol chitosan bearing hydrophobic moieties as carriers for doxorubicin: In vivo biodistribution and anti tumour activity. Biomaterials, 27(1), 119-126.
69. Illum, L., Hunneyball, I. M., and Davis, S. S., 1986. The effect of hydrophilic coatings on the uptake of colloidal particles by the liver and by peritoneal macrophages, Int. J. Pharm., 29, 53-65.
70. Irache, J. M., Durrer, C., Duchene, D., and Ponchel, G., 1996. Bioadhesion of lectin latex conjugates to rat intestinal mucosa. Pharm. Res., 13, 1716.
71. Israelachvili, J. N., 1992. Intermolecular and Surface Forces. London, Harcourt Brace and Company.
72. Jeong, Y. L., Kang, M. K., Sun, H. S., et al., 2004. All trans retinoic acid release from core shell type nanoparticles of polyepsilon caprolactone poly(ethylene glycol) diblock copolymer. Int. J. Pharm., 273, 95-107.
73. Jiang, J., Tong, X., and Zhao, Y., 2005. A new design for light-breakable polymer micelles. J. Am. Chem. Soc., 127, 8290-8291.
74. Jones, M. S., 1999. Effect of pH on the lower critical solution temperatures of random copolymers of N-isopropylacrylamide and acrylic acid. Eur. Polym. J., 35(5), 795-801.
75. Kabanova, A. V. and Gendelman, H. E., 2007. Nanomedicine in the diagnosis and therapy of neurodegenerative disorders. Progr. Polym. Sci., 32, 1054-1082.
76. Kalyanasundaram, K. and Thomas, J. K. 1977. Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies of micellar systems. J. Am. Chem. Soc., 99, 2039-2044.
77. Kang, B. K. and Lee, J. S., 2004. Development of self-microemulsifying drug delivery systems (SMEDDS) for oral bioavailability enhancement of simvastatin in beagle dogs. Int. J. Pharm., 274(1-2), 65-73.
78. Kaparissides, C., Alexandridou, S., Kotti, K., and Chaitidou, S., 2006. Recent advances in novel drug delivery systems. Available at http://www.azonano.com/oars.asp
79. Kataoka, K., Harada, A., and Nagasaki, Y., 2001. Block copolymer micelles for drug delivery: Design, characterization and biological significance. Adv. Drug Deliv. Rev., 47, 113-131.
80. Kaul, G. and Amiji, M., 2002. Long circulating poly ethylene glycol modified gelatin nanoparticles for intracellular delivery. Pharm. Res., 19(7), 1061-1067.
81. Kaul, G. and Amiji, M., 2004. Biodistribution and targeting potential of poly(ethylene glycol)-modified gelatin nanoparticles in subcutaneous murine tumor model. J. Drug Targeting. 12(9-10), 585-591.
82. Khoo, S. M., Humberstone, A. J., Porter, C. J. H., et al., 1998. Formulation design and bioavailability assessment of lipidic self-emulsifying formulations of halofantrine. Int. J. Pharm., 167(1-2), 155-164.
83. Kim, S. Y. and Kim, J. H., 2001. Drug-releasing kinetics of MPEG/PLLA block copolymer micelles with different PLLA block lengths. J. Appl. Polym. Sci., 82(10), 2599-2605.
84. Kirby, C. J. and Gregoriadis, G., 1980. Action of indomethacin on neutral and positively charged monolayers. Life Sci., 27, 2223-2230.
85. Klevens, H. B., 1950. Solubilization. Chem. Rev., 47, 1.
86. Kolthoff, I. M. and Stricks, W., 1948. Solubilization of dimethylaminoazobenzene in solutions of detergents. I. The effect of temperature on the solubilization and upon the critical concentration. J. Phys. Colloid Chem., 52, 195.
87. Kosaric, N., Cairns, W. L., and Gray N. C. C., 1987. Introduction: Biotechnology and the surfactant Industry. In: Biosurfactants and Biotechnology. Surfactant Science Series. N. Kosaric, W.L. Cairns, and N. C. C. Gray (Eds), Vol. 25, pp. 1-21. New York, Marcel Dekker.
88. Kositza, M. J., Bohne, C., Hatton, T. A., et al., 1999. Micellization dynamics of PEO-PPO-PEO block copolymers measured by stopped flow. Progr. Colloid Polym. Sci., 112, 146-151.
89. Kreuter, J., 1991. Nanoparticles based drug delivery systems. J. Control. Release, 16, 169-176.
90. Kunii, R. and Onishi, H., 2007. Preparation and antitumor characteristics of PLA/(PEG-PPG-PEG) nanoparticles loaded with camptothecin. Eur. J. Pharm. Biopharm., 67(1), 9-17.
91. Kwon, G. S., 1998. Diblock copolymer nanoparticles for drug delivery. Crit. Rev. Ther. Drug Carrier Syst., 15, 481-512.
92. Kwon, G. and Naito, M., 1997. Block copolymer micelles for drug delivery: Loading and release of doxorubicin. J. Control. Release, 48(2-3), 195-201.
93. Lasic, D. D., 1990. On the thermodynamic stability of liposomes. J. Colloid Interface Sci., 140, 302-304.
94. Lattuada, R. and Martini, A., 1998. SmeddsR (self micro-emulsifying drug delivery systems) for oral administration of an immunosuppressive drug. Eur. J. Pharm. Sci., 6(1), S67.
95. Law, S. L., Huang, K. J., and Chiang, C. H., 2000. Acyclovir containing liposomes for potential ocular delivery. Corneal penetration and absorption. J. Control. Release, 631(1-2), 135-140.
96. Lawrence, A. S. C., 1937. Internal solubility in soap micelles. Trans. Faraday Soc., 33(325), 815.
97. Lecommandoux, S., Rodriguez-Hernandez, J., Checot, F., et al., 2005. Toward "smart" nano-objects by selfassembly of block copolymers in solution. Progr. Polym. Sci., 30(7), 691-724.
98. Leroux, J.-C., Taillefer, J., Jones, M.-C., and Brasseur, N., 2000. Preparation and characterization of pHresponsive polymeric micelles for the delivery of photosensitizing anticancer drugs. J. Pharm. Sci., 89, 52-62.
99. Lewis, D. H., 1990. Controlled release of bioactive agents from lactide/glycolide polymers. In: Biodegradable Polymers as Drug Carrier Systems, M. Chasin and R. Langer (Eds), pp. 1-43. New York, Marcel Dekker.
100. Linse, P. 2000. Modelling of self-assembly of block copolymers in selective solvent. In: Amphiphilic Block Copolymers: Self Assembly and Applications, B. Lindman, P. Alexandridis (Eds), pp. 13-40. Amsterdam, Elsevier.
101. Liu, C. G., Desai, K. G., Chen, X. G., and Park, H. J., 2005. Preparation and characterization of nanoparticles containing trypsin based on hydrophobically modified chitosan. J. Agric. Food Chem., 53(5), 1728-1733.
102. Liu, H., Pan, W. S., Tang, R., and Luo, S. D., 2004. Topical delivery of acyclovir palmitate liposome formulations through rat skin in vitro. Pharmazie, 59, 203-206.
103. Lu, J.-L. and Wang, J.-C., 2008. Self-microemulsifying drug delivery system (SMEDDS) improves anticancer effect of oral 9-nitrocamptothecin on human cancer xenografts in nude mice. Eur. J. Pharm. Biopharm., 69(3), 899-907.
104. Lu, Z., Yeh, T. K., Tsai, M., Au, J. L., and Wientjes, M. G., 2004. Paclitaxel loaded gelatin nanoparticles for intravesical bladder cancer therapy. Clin. Cancer Res., 10(22), 7677-7684.
105. Lukyanov Anatoly, N. and Torchilin Vladimir, P., 2004. Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. Adv. Drug Deliv. Rev., 56, 1273-1289.
106. Maestrelli, F., Garcia-Fuentes, M., Mura, P., and Alonso, M. J., 2006. A new nanocarrier consisting of chitosan and hydroxypropylcyclodextrin. Eur. J. Pharm. Biopharm., 69, 79-86.
107. Malmsten, M., 2002. Surfactants and Polymers in Drug Delivery. New York, Marcel Dekker.
108. Manosroi, A., Konganeramit, L., and Manosroi, J., 2004. Stability and transdermal absorption of topical amphotericin B liposome formulations. Int. J. Pharm., 270, 279-286.
109. Mansourie, S., Cuie, Y., Winnik, F., et al., 2006. Characterization of folate chitosan DNA nanoparticles for gene therapy. Biomaterials, 27(9), 2060-2065.
110. Matsumoto, M., Matsuzawa, Y., Noguchi, S., Sakai, H., and Abe, M., 2004. Structure of Langmuir Blodgett films of amphiphilic cyclodextrin and water soluble benzophenone. Mol. Cryst. Liq. Cryst., 425, 197-204.
111. McCarron, P. A., Donnelly, R. F., Canning, P. E., et al., 2004. Bioadhesive non drug loaded nanoparticles as modulators of candidial adherence to buccal epithelial cells: A potentially novel prophylaxis for candidosis. Biomaterials, 25, 2399-2407.
112. Misselwitz, B. and Sasche, A., 1997. Interstitial MR lymphography using GD-carrying liposomes. Acta Radio. Suppl., 412, 51-55.
113. Moffitt, M., Khougaz, K., and Eisenberg, A., 1996. Micellization of ionic block copolymers. Acc. Chem. Res., 29(2), 95-102.
114. Moghimi, S. M. and Hunter, A. S., 2001. Recognition by macrophages and liver cells of opsonized phospholipid vesicles and phospholipid headgroups. Pharm. Res., 18, 1-8.
115. Mrozek, E., Rhoades, C. A., Allen, J., Hade, E. M., and Shapiro, C. L., 2005. Phase I trial of liposomal encapsulated doxorubicin (MyocetTM, D-99) and weekly docetaxel in advanced breast cancer patients. Ann. Oncol., 16, 1087-1093.
116. Mueller, R. H. and Wallis, K. H., 1993. Surface modification of i.v. injectable biodegradable nanoparticles with poloxamer polymers and Poloxamine 908. Int. J. Pharm., 89, 25-31.
117. Mukherjee, P., 1972. Size distribution of small and large micelles. Multiple equilibrium analysis. J. Phys. Chem., 76, 565.
118. Muller, N. 1972. Kinetics of micelle dissociation by temperature-jump techniques. Reinterpretation. J. Phys. Chem., 76, 3017.
119. Munk, P. 1996. Equilibrium and nonequilibrium polymer micelles. In: Solvents and Selforganization of Polymer. NATO ASI Series, Series E: Applied Sciences, S. E. Webber, P. Munk, and Z. Tuzar (Eds), Vol. 327, pp. 19-32. Dordrecht, Kluwer Academic.
120. Murray, R. C. and Hartley, G. S., 1935. Equilibrium between micelles and simple ions, with particular reference to the solubility of long-chain salts. Trans. Faraday Soc. 31, 185.
121. Nagarajan, R. 1996. Solubilization of hydrophobic substances by block copolymer micelles in aqueous solution. In: Solvents and Selforganization of Polymer. NATO ASI Series, Series E: Applied Sciences, S. E. Webber, P. Munk, and Z. Tuzar (Eds), Vol. 327, pp. 121-165. Dordrecht, Kluwer Academic.
122. New, R. R. C., 1989. Introduction. In: Liposomes: A Practical Approach. R. R. C. New (Eds), p. 1. Oxford, London, OIRL Press.
123. Nicolaos, G., Crauste-Manciet, Farinotti, R., et al., 2003. Improvement of cefpodoxime proxetil oral absorption in rats by an oil-in-water submicron emulsion. Int. J. Pharm., 263(1-2), 165-171.
124. Nishiyama, N., Bae, Y., Miyata, K., et al., 2005. Smart polymeric micelles for gene and drug delivery. Drug Discov. Today: Technol., 2(1), 21-26.
125. Noolandi, J. and Hong, K. M., 1982. Interfacial properties of immiscible homopolymer blends in the presence of block copolymers. Macromolecules, 15, 482-492.
126. Nowakowska, M. and Zczubiałka, K., 2003. Response of micelles formed by smart terpolymers to stimuli studied by dynamic light scattering. Polymer, 44, 5269-5274.
127. Opanasopit, P. and Yokoyama, M., 2004. Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting. Pharm. Res., 21(11), 2001-2008.
128. Oussoren, C. and Storm, G., 2001. Liposomes to target the lymphatics by subcutaneous administration. Adv. Drug Deliv. Rev., 50, 143-156.
129. Palamakula, A., Nutan, M. T. H., and Khan, M. A., 2004. Response surface methodology in optimization and characterization of limonene-based Coenzyme Q10 from self-nanoemulsified capsule dosage form. AAPS Pharm. Sci. Technol., 5(4), 1-8.
130. Pandey, R., Ahmad, Z., Sharma, S., and Khuller, G. K., 2005. Inhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis. Int. J. Antimicrob. Agents, 26(4), 298-303.
131. Papahadjopoulos, D., Vali, W. J., Jacobson, K., and Poste, G., 1975. Effects of local anaesthetics on membrane properties I changes in the fluidity of phospholipids bilayers. Biochim. Biophys. Acta, 394, 504-519.
132. Park, E. K., Lee, S. B., and Lee, Y. M., 2005. Preparation and characterization of methoxy poly(ethylene glycol)/poly(epsilon-caprolactone) amphiphilic block copolymeric nanospheres for tumour specific folate mediated targeting of anticancer drugs. Biomaterials, 26, 1053-1061.
133. Patton, J. S., Fishburn, C. S., and Weers, J. G., 2004. The lungs as a portal for entry of systemic drug delivery. Proc. Am. Thorac. Soc., 1, 339-344.
134. Paveli, Z., Skalko-Basnet, N., and Schubert, R., 2001. Liposomal gels for vaginal drug delivery. Int. J. Pharm., 219, 139-149.
135. Peer, D. and Margalit, R., 2004. Tumour targeted hyaluronan nanoliposomes increase the antitumour activity of liposomal doxorubicin in syngeneic and human xenograft mouse tumour models. Neoplasia, 6, 343-353.
136. Perlman, M. E., Murdande, S. B., Gumkowski, M. J., et al., 2008. Development of a self-emulsifying formulation that reduces the food effect for torcetrapib. Int. J. Pharm., 351(1-2), 15-22.
137. Peroche, S., Degobert, G., Putaux, J. L., Blanchin, M. G., Fessi, H., and Parrot-Lopez, H., 2005. Synthesis and characterization of novel nanospheres made from amphiphilic perfluoroalkylthio-beta cyclodextrins. Eur. J. Pharm. Biopharm., 60, 123-131.
138. Perrie, Y., Barralet, J. E., McNeil, S., and Vangala, A., 2004. Surfactant vesicle mediated delivery of DNA vaccines via the subcutaneous route. Int. J. Pharm., 284, 31-41.
139. Pethica, B. A., 1960. Proceedings of the 3rd International Congress on Surface Activity, Cologne. 1, 212.
140. Pfeifer, B. A., Burdick, J. A., Little, S. R., and Langer, R., 2005. Poly(ester-anhydride) poly(beta-amino ester) micro and nanospheres: DNA encapsulation and cellular transfection. Int. J. Pharm., 304, 210-219.
141. Pich, A. and Schiemenz, N., 2006. Preparation of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) particles in O/W emulsion. Polymer, 47(6), 1912-1920.
142. Ping Zhang and Ying Liu, 2008. Preparation and evaluation of self-microemulsifying drug delivery system of oridonin. Int. J. Pharm., 355(1-2), 269-276.
143. Pitt, C. G., 1990. Poly(E-caprolactone) and its co polymers, In: Biodegradable Polymers as Drug Carrier Systems, M. Chasin and R. Langer (Eds), p. 71. New York, Marcel Dekker.
144. Price, C., 1982. Colloidal properties of block copolymers. In: Developments in Block Copolymers, Vol. 1, p. 39-79. London, Applied Science.
145. Quintana, J. R., Villacampa, M., and Katime, I., 1996. Block copolymers: Micellization in solution. In: Polymer Material Encyclopedia, Vol. 1, pp. 815-821. Boca Raton, FL, CRC Press.
146. Quirk, R. P., Kinning, D. J., and Fetters, L. J., 1989. Block Copolymers. Comprehensive Polymer Science, Vol. 7, pp. 1-26. Oxford, Pergamon Press.
147. Rapoport, N., 2007. Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery. Progr. Polym. Sci., 32, 962-990.
148. Reigelman, S., Allawala, N. A., Hrenoff, M. K., et al. 1958. The ultraviolet absorption spectrum as a criterion of the type of solubilization. J. Colloid Sci., 13, 208.
149. Reis, C. P., Neufeld, R. J., Ribeiro, A. J., et al., 2006. Nanoencapsulation I. Methods for preparation of drugloaded polymeric nanoparticles. Nanomedicine, 2(1), 8-21.
150. Riess, G., 2003. Micellization of block copolymers. Prog. Polym. Sci., 28, 1107-1170.
151. Riess, G., Hurtrez, G., and Bahadur, P., 1985. Block copolymers. In: Encyclopedia of Polymer Science and Engineering, H. F. Mark and J. I. Kroschwitz (Eds), 2nd ed., Vol. 2, pp. 324-434. New York, Wiley.
152. Rodrigues, L., Banat Ibrahim, M., Teixeira, J., et al., 2006. Biosurfactants: Potential applications in medicine. J. Antimicrob. Chemother., 57(4), 609-618.
153. Rodriguez, S. Galindo, Allemann, E., et al. 2004. Physicochemical parameters associated with nanoparticle formation in the salting-out, emulsification-diffusion, and nanoprecipitation methods. Pharm. Res., 21, 1428-1439.
154. Rodriguez Stephen, C. and Singer Edward, J., 1996. Toxicology of polyoxyalkylene block copolymer. In: Non Ionic Surfactants, Surfactant Science Series, V. M. Nace (Ed.), Vol. 60, pp. 211-231. New York, Marcel Dekker.
155. Rosler, A., Vandermeulen, G. W.M., and Klok, H.-A., 2001. Advanced drug delivery devices via self-assembly of amphiphilic block copolymers. Adv. Drug Deliv. Rev., 53, 95-108.
156. Sadzuka, Y., Horota, S., and Sonobe, T., 2000. Intraperitoneal administration of doxorubicin encapsulating liposomes against peritoneal dissemination. Toxicol. Lett., 116, 51-59.
157. Scherlund, M., Malmsten, M., Holmqvist, P., et al., 2000. Thermosetting microemulsions and mixed micellar solutions as drug delivery systems for periodontal anesthesia. Int. J. Pharm., 194(1), 103-116.
158. Schott, H., 1967. Solubilization of a water-insoluble dye. II. J. Phys. Chem., 71, 3611.
159. Schwarz, L. A., Johnson, J. L., Black, M., et al., 1996. Delivery of DNA-cationic liposome complexes by small particle aerosol. Hum. Gene Ther., 24, 35-36.
160. Shah, N. H., Carvajal, M. T., Patel, C. I., et al., 1994. Self-emulsifying drug delivery systems (SEDDS) with polyglycolized glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs. Int. J. Pharm., 106, 15-23.
161. Shahiwala, A. and Misra, A., 2004. Nasal delivery of levonorgestrol for contraception: An experimental study in rats. Fertil. Steril., 81(Suppl. 1), 893-898.
162. Shimizu, K., Takada, M., Asai, T., Kuromi, K., Baba, K., and Oku, N., 2002. Cancer chemotherapy by liposomal 6-[[2-(dimethyal amino ethyl]amino]-3-hydroxy-7H-indeno[2,1-c] quinolin-7-one dihydrochloride (TAS-103), a novel anticancer gent. Biol. Pharm. Bull., 25, 1385-1387.
163. Skiba, M., Skiba-Lahiani, M., and Arnaud, P., 2002. Design of nanocapsules based on novel fluorophilic cyclodextrin derivatives and their potential role in oxygen delivery. J. Inclusion Phenom. Macrocyclic Chem., 44, 151-154.
164. Soppimath, K. S., Aminabhavi, T. M., Kulkarni, A. R., et al., 2001. Biodegradable polymeric nanoparticles as drug delivery devices. J. Control. Release, 70(1-2), 1-20.
165. Stover, T. C., Sharma, A., Robertson, G. P., and Kester, M., 2005. Systemic delivery of liposomal short chain ceramide limits solid tumour growth in murine models of breast adenocarcinoma. Clin. Cancer Ther., 11, 3465-3474.
166. Tadros Tharwat, F., 2005. Applied Surfactants: Principles and Applications, pp. 2-17. Hoboken, NJ, Wiley.
167. Thanatuksorn, P., Kawai, K., Hayakawa, M., et al., 2009. Improvement of the oral bioavailability of coenzyme Q10 by emulsification with fats and emulsifiers used in the food industry. LWT-Food Sci. Technol., 42(1), 385-390.
168. Topp, M. D. C., Dijkstra, P. J., Talsma, H., et al., 1997. Thermosensitive micelle-forming block copolymers of poly-(ethylene glycol) and poly(N-isopropylacrylamide). Macromolecules, 30(26), 8518-8520.
169. Torchilin, V. P., 1998. Liposomes as carriers of contrast agents in in vivo diagnostics. In: Medical Applications of Liposomes, D. D. Lasic and D. Papahadjapoulos (Eds.), p. 515. Oxford, Elsevier.
170. Toub, N., Angiari, C., Eboue, D., et al., 2005. Cellular fate of oligonucleotides when delivered by nanocapsules of poly(isobutylcyanoacrylate). J. Control. Release, 106, 209-213.
171. Tuzar, Z. and Kratochvil, P., 1993. Micelles of block and graft copolymers in solution. In: Surface and Colloid Science, E. Matijevic (Ed.), Vol. 15, pp. 1-83. New York, Plenum Press.
172. Uhrich, K. E., Cannizzaro, S. M., et al., 1999. Polymeric systems for controlled drug release. Chem. Rev., 99, 3181-3198.
173. U.S. Pat. 6288121, Stefano Bader, Helsinn Healthcare Inc., 2001. Nimesulide topical formulations in the form of liquid crystals.
174. U.S. Pat 6306434, Chung II Hong, Chong Kun Dang Corp. (KR), 2001. Pharmaceutical composition comprising cyclosporine solid state microemulsion.
175. U.S. Pat. 6623765, Donn, M. Denis, University of Florida, Research Foundation, 2003. Microemulsion and micelle system for solubilising drugs.
176. U.S. Pat. 6638522, Nirmal Mulye, Pharmasolutions, 2003. Microemulsion concentrate composition of cyclosporine.
177. U.S. Pat. 6703034, Balraj, S. Parmar, University of Florida, 2004. Neem oil microemulsion without cosurfactants and alcohol and the process to form the same.
178. U.S. Pat. 7115565, Ping Goa, Pharmacia and Upjohn Company, 2006. Chemotherapeutic microemulsions composition of paclitaxel with improved oral bioavailability.
179. van Nostrum, C. F., 2004. Polymeric micelles to deliver photosensitizers for photodynamic therapy. Adv. Drug Deliv. Rev., 56, 9-16.
180. Vandervoort, J. and Ludwig, A., 2004. Preparation and evaluation of drug loaded gelatin nanoparticles for topical ophthalmic use. Eur. J. Pharm. Biopharm., 57(2), 251-261.
181. Verschraegen, C. F., Gilbert, B. E., Loyer, E., et al., 2004. Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro camphothecin in patients with advanced pulmonary malignancies. Clin. Cancer Res., 100, 1449-1458.
182. Vyas, S. P. and Uchegbu, I. F., 1998. Non-ionic surfactant based vesicles (niosomes) in drug delivery. Int. J. of Pharm., 172, 33-70.
183. Vyas, S. P., Kannan, M. P., Jain, S., Mishra, V., and Singh, P., 2004. Design of liposomal aerosols for improved delivery of rifampicin to alveolar macrophages. Int. J. Pharm., 269, 37-49.
184. Vyas, S. P., Quraishi, S., Gupta, S., and Jaganathan, K. S., 2005. Aerosolized liposome based delivery of amphotericin B to alveolar macrophages. Int. J. Pharm., 296, 12-25.
185. Wang, D., Nagata, L. P., Christopher, M. E., et al., 2004. Intranasal immunization with liposome-encapsulated plasmid DNA encoding influenza virus hemagglutinin elicits mucosal, cellular and humoral immune responses. J. Clinical Virology. 31(1), 99-106.
186. Wang, J.-J., Sung, K. C., Yeh, C.-H., and Fang, J.-Y., 2008. The delivery and antinociceptive effects of morphine and its ester prodrugs from lipid emulsions. Int. J. Pharm., 353(1-2), 95-104.
187. Wells, J. M., Li, H., Sen, A., Jahreis, G. P., and Hui, S. W., 2000. Electroporation enhanced gene delivery in mammary tumours. Gene Ther., 7, 541-547.
188. West, J. L., Sershen, S. R., Westcott, S. L., et al., 2000. Temperature-sensitive polymer-nanoshell composites for photothermally modulated drug delivery. J. Biomed. Mater. Res., 51, 293-296.
189. Willimann, H., Walde, J. I., Luisi, A., Gazzaniga, A., and Dtroppolo, F., 1992. Lecithin organogels as matrix for transdermal transport of drugs. J. Pharm. Sci. 81(9), 871-874.
190. Wooley, K. L., Thurmond, K. B., Kowalewski, T., 1996. Water-soluble needle-like structures: The preparation of shell-cross-linked small particles. J. Am. Chem. Soc., 118, 7239-7240.
191. Wu, P. C., Tsai, Y. H., Liao, C. C., et al., 2004. Characterization and biodistribution of cefoxitin loaded liposomes. Int. J. Pharm., 271, 31-39.
192. Wu, W. and Wang, Y., 2006. Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system. Eur. J. Pharm. Biopharm., 63(3), 288-294.
193. Yamamoto, Y., Nagasaki, Y., Kato, M., and Kataoka, K., 1999. Surface charge modulation of poly(ethylene glycol)-poly(d,l-lactide) block copolymer micelles: conjugation of charged peptides. Colloids Surf. B, 16, 135-146.
194. Yokoyama, M., 1992. Block copolymers as drug carriers. Crit. Rev. Ther. Drug Carrier Syst., 9, 213-248.
195. Yonese, M., Toyotama, A., Kugimiya, S., et al., 2001. Preparation of a novel aggregate like sugar-ball micelle composed of poly(methylglutamate) and poly(ethyleneglycol) modified by lactose and its molecular recognition by lectin. Chem. Pharm. Bull., 49, 169-172.
196. Zana, R., 2000. Fluorescence studies of amphiphilic block copolymers in solution. In: Amphiphilic Block Copolymers: Self Assembly and Applications, B. Lindman and P. Alexandridis (Eds), pp. 221-252. Amsterdam, Elsevier.