Efficacy of mometasone furoate microemulsion in the treatment of erosive-ulcerative oral lichen planus: Pilot study

Journal of Oral Pathology and Medicine

Volumn 33, Issue 7, 2004, Pages 381-385

  Aguirre, José M ^a   Bagan J V ^b   Rodriguez, C ^a   Jimenez, Y ^b   Martinez Conde R ^a   Diaz De Rojas F ^c   Ponte, A ^c  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

^c Schering Plough   (Spain)

Author keywords

Erosive ulcerative; Mometasone; OLP; Treatment

Indexed keywords

CLOBETASOL; FLUCONAZOLE; MOMETASONE FUROATE; NYSTATIN;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CORTICOSTEROID THERAPY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; DRUG SAFETY; EROSION; ERYTHEMA; FEMALE; HUMAN; IMMUNOPATHOLOGY; LICHEN PLANUS; MALE; MICROEMULSION; MOUTH INFECTION; MOUTH LICHEN PLANUS; MOUTH ULCER; MOUTHWASH; PAIN; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; SIDE EFFECT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STUDENT T TEST; SURFACE PROPERTY; SYMPTOMATOLOGY; THRUSH;

ADMINISTRATION, TOPICAL; ADULT; AGED; ANTI-INFLAMMATORY AGENTS; EMULSIONS; FEMALE; GLUCOCORTICOIDS; HUMANS; LICHEN PLANUS, ORAL; MALE; MIDDLE AGED; MOUTHWASHES; PILOT PROJECTS; PREGNADIENEDIOLS;

EID: 3342922530     PISSN: 09042512     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2004.00213.x     Document Type: Article

References (23)

1. Silverman S, Gorsky M, Lozada-Nur F, Giannotti K. A prospective study of findings and management in 214 patients with oral lichen planus. Oral Surg Oral Med Oral Pathol 1991; 72: 665-70.
2. Bagan JV, Milian MA, Peñarrocha M, Jimenez Y. A clinical study of 205 patients with oral lichen planus. J Oral Maxillofac Surg 1992; 50: 116-8.
3. Scully C, Beyli M, Ferreiro MC, et al. Update on oral lichen planus: Etiopathogenesis and management. Crit Rev Oral Biol Med 1998; 9: 86-122.
4. Wun C, Silverman SJ, Lozada-Nur F, Mayer P, Watson JJ. Oral lichen planus: patient profile, disease progression and treatment responses. J Am Dent Assoc 2001; 132: 901-9.
5. Myers SL, Rhodus NL, Parsons HM, Hodges JS, Kaimal S. A retrospective survey of oral lichenoid lesions: revisiting the diagnostic process for oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 93: 676-81.
6. Olivier V, Lacour JP, Mpusnier A, Garraffo R, Monteil RA, Ortonne JP. Treatment of chronic erosive oral lichen planus with low concentrations of topical tacrolimus: an open prospective study. Arch Dermatol 2002; 138: 1335-8.
7. Lozada-Nur F, Miranda C, Maliski R. Double-blind clinical trial of 0.05% clobetasol propionate ointment in orabase and 0.05% fluocinocide ointment in orabase in the treatment of patients with oral vesiculoerosive diseases. Oral Surg Oral Med Oral Pathol 1994; 77: 598-604.
8. Harpenau LA, Plemons JM, Rees TD. Effectiveness of a low dose of cyclosporine in the management of patients with oral erosive lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995; 80: 161-7.
9. Buajeeb W, Kraivaphan P, Pobrusksa Ch. Efficacy of topical retinoic acid compared with topical fluocinolone acetonide in the treatment of oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 83: 21-5.
10. Cribier B, Frances C, Chosidow O. Treatment of lichen planus. An Evidence-Based Medicine analysis of efficacy. Arch Dermatol 1998; 134: 1521-30.
11. Scully C, Eisen D, Carrozzo M. Management of oral lichen planus. Am J Clin Dermatol 2000; 1: 287-306.
12. Hegarty AM, Hodgson TA, Lewsey JD, Porter SR. Fluticasone propionate spray and betamethasone sodium phosphate mouthrinse: a randomized crossover study for the treatment of symptomatic oral lichen planus. J Am Acad Dermatol 2002; 47: 271-9.
13. Lozada-Nur F, Miranda C. Oral lichen planus: topical and systemic therapy. Sem Cutan Med Surg 1997; 16: 295-300.
14. Gonzalez-Moles MA, Morales P, Rodriguez-Archilla A, Ruiz-Avila I, Gonzalez-Moles S. Treatment of severe chronic oral erosive lesions with clobetasol propionate in aqueous solution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 93: 264-70.
15. Nashan D, Nowok K, Luger T. Efficacy and safety of the new topical corticosteroid mometasone furoate for treatment of inflammatory skin diseases. A multicenter study. H-G-Z Hautkr 1996; 71: 263-6.
16. Prakash A, Benfield P. Topical mometasone. A review of its pharmacological properties and therapeutic use in the treatment of dermatological disorders. Drugs 1998; 55: 145-63.
17. Teixeira F, Mosqueda-Taylor A, Montano S, Dominguez-Soto L. Treatment of recurrent oral ulcers with mometasone furoate lotion. Postgrad Med J 1999; 75: 574.
18. Scott J, Huskisson EC. Graphic representation of pain. Pain 1976; 2: 175-84.
19. Odds FC. Candida and candidosis. London: Bailliere-Tindal, 1988.
20. Wittes J, Brittain E. The role of internal pilot studies in increasing the efficiency of clinical trials. Stat Med 1990; 9: 65-72.
21. Voute ABE, Schulten EAJM, Langendijk PNJ, Kostense PJ, van der Waal I. Fluocinonide in an adhesive base for treatment of oral lichen planus: a double-blind, placebo-controlled clinical study. Oral Surg Oral Med Oral Pathol 1993; 75: 181-5.
22. Robertson DB, Maibach HI. Topical glucocorticoids. In: Schleimer RP, Claman HN, Oronsky A, eds. Anti-inflammatory steroid action. San Diego: Academic Press, 1989; 494-524.
23. Onrust SV, Lamb HM. Mometasone furoate. A review of its intranasal use in allergic rhinitis. Drugs 1998; 56: 725-745.