UHRF1 discriminates against binding to fully-methylated CpG-Sites by steric repulsion

Biophysical Chemistry

Volumn 171, Issue , 2013, Pages 38-45

  Bianchi, Caterina ^a   Zangi, Ronen ^a,b  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

DNA methylation; Epigenetics; Free energy calculation; Molecular dynamics simulation; Protein DNA interaction

Indexed keywords

CYTOSINE; UBIQUITIN; UBIQUITIN LIKE CONTAINING PHD AND RING FINGER DOMAINS 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CPG ISLAND; DNA METHYLATION; HYDROGEN BOND; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; STEREOCHEMISTRY; SUBSTITUTION REACTION;

CCAAT-ENHANCER-BINDING PROTEINS; CPG ISLANDS; DNA; DNA METHYLATION; HUMANS; MOLECULAR DYNAMICS SIMULATION; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS;

EID: 84872332138     PISSN: 03014622     EISSN: 18734200     Source Type: Journal    
DOI: 10.1016/j.bpc.2012.10.002     Document Type: Article

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