Mechanism of DNA Methylation: The Double Role of DNA as a Substrate and as a Cofactor

Journal of Molecular Biology

Volumn 400, Issue 3, 2010, Pages 632-644

  Zangi, Ronen ^a,b   Arrieta, Ana ^a   Cossío, Fernando P ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

DNA as cofactor; DNA cytosine methyltransferase; DNA phosphate group; Methylation reaction mechanism; Quantum mechanical calculations

Indexed keywords

ARGININE; CYSTEINE; CYTOSINE; DNA METHYLTRANSFERASE; GLUTAMIC ACID; NUCLEOPHILE; SERINE; THYMIDYLATE SYNTHASE;

ARTICLE; CATALYSIS; DNA METHYLATION; ENZYME ACTIVITY; PRIORITY JOURNAL;

BACTERIA (MICROORGANISMS);

EID: 77954383792     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.05.021     Document Type: Article

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