Gender differences in the long-chain polyunsaturated fatty acid status: Systematic review of 51 publications

Annals of Nutrition and Metabolism

Volumn 62, Issue 2, 2013, Pages 98-112

  Lohner, Szimonetta ^a   Fekete, Katalin ^a   Marosvölgyi, Tamás ^a   Decsi, Tamás ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Arachidonic acid; Docosahexaenoic acid; Gender differences; Long chain polyunsaturated fatty acids; Sex hormones

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; LINOLEIC ACID; LIPID; LONG CHAIN POLYUNSATURATED FATTY ACID; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; COCHRANE LIBRARY; DATA EXTRACTION; ERYTHROCYTE MEMBRANE; HUMAN; LIPID BLOOD LEVEL; LIPID COMPOSITION; MEDLINE; META ANALYSIS; PHOSPHOLIPID BLOOD LEVEL; PLASMA; PRIORITY JOURNAL; PUBLICATION; REVIEW; SCOPUS; SEX DIFFERENCE; SYSTEMATIC REVIEW;

SCOPUS;

EID: 84872271189     PISSN: 02506807     EISSN: 14219697     Source Type: Journal    
DOI: 10.1159/000345599     Document Type: Review

References (65)

1. Burdge GC, Wootton SA. Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. Br J Nutr 2002; 88: 411-420
2. Harnack K, Andersen G, Somoza V. Quantitation of alpha-linolenic acid elongation to eicosapentaenoic and docosahexaenoic acid as affected by the ratio of n6/n3 fatty acids. Nutr Metab (Lond) 2009; 6: 8
3. Hodson L, Skeaff CM, Fielding BA. Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake. Prog Lipid Res 2008; 47: 348-380
4. Decsi T, Kennedy K. Sex-specific differences in essential fatty acid metabolism. Am J Clin Nutr 2011; 94: 1914S-1919S
5. Ando T, Yanagihashi T, Wakisaka I, Tomari T. Relationship between serum fatty acid composition and life style and/or health status in a rural population in Kagoshima (in Japanese). Nihon Koshu Eisei Zasshi 1990; 37: 752-760
6. Antonini FM, Bucalossi A, Petruzzi E, Simoni R, Morini PL, D'Alessandro A. Fatty acid composition of adipose tissue in normal, atherosclerotic and diabetic subjects. Atherosclerosis 1970; 11: 279-289
7. Araki K, Akiyam Y, Murayama H, Fukase O, Yamamoto A, Fujiwara T, Oshiba K, Kawaraya C, Otachi J, Masumoto K. Relationship between dietary intake and serum fatty acids compositions of the residents in Hyogo Prefecture (in Japanese). Nihon Koshu Eisei Zasshi 1990; 37: 620-628
8. Bakewell L, Burdge GC, Calder PC. Polyunsaturated fatty acid concentrations in young men and women consuming their habitual diets. Br J Nutr 2006; 96: 93-99
9. Bolton-Smith C, Woodward M, Tavendale R. Evidence for age-related differences in the fatty acid composition of human adipose tissue, independent of diet. Eur J Clin Nutr 1997; 51: 619-624
10. Brouwer DA, Van Der Dijs FP, Leerink CB, Steward HN, Kroon TA, Suverkropp GH, Romer JW, Van Doormaal JJ, Muskiet FA. The dietary fatty acids of patients with coronary artery disease and controls in Curacao. Implications for primary and secondary prevention. West Indian Med J 1997; 46: 53-56
11. Cheng HH, Wen YY, Chen C. Serum fatty acid composition in primary school children is associated with serum cholesterol levels and dietary fat intake. Eur J Clin Nutr 2003; 57: 1613-1620
12. Christensen JH, Christensen MS, Dyerberg J, Schmidt EB. Heart rate variability and fatty acid content of blood cell membranes: a dose-response study with n-3 fatty acids. Am J Clin Nutr 1999; 70: 331-337
13. di Giuseppe R, De Lorgeril M, Salen P, Laporte F, Di Castelnuovo A, Krogh V, Siani A, Arnout J, Cappuccio FP, Van Dongen M, et al. Alcohol consumption and n-3 polyunsaturated fatty acids in healthy men and women from 3 European populations. Am J Clin Nutr 2009; 89: 354-362
14. Elizondo-Montemayor L, Serrano-González M, Ugalde-Casas PA, Cuello-García C, Borbolla-Escoboza JR. Plasma phospholipid fatty acids in obese male and female Mexican children. Ann Nutr Metab 2010; 57: 234-241
15. Fernandez-Real JM, Vayreda M, Casamitjana R, Gonzalez-Huix F, Ricart W. Circulating granulocyte-macrophage colony-stimulating factor and serum fatty acid composition in men and women. Metabolism 2001; 50: 1479-1483
16. Geppert J, Min Y, Neville M, Lowy C, Ghebremeskel K. Gender-specific fatty acid profiles in platelet phosphatidyl-choline and -ethanolamine. Prostaglandins Leukot Essent Fatty Acids 2010; 82: 51-56
17. Giltay EJ, Gooren LJ, Toorians AW, Katan MB, Zock PL. Docosahexaenoic acid concentrations are higher in women than in men because of estrogenic effects. Am J Clin Nutr 2004; 80: 1167-1174
18. Glew RH, Chuang LT, Berry T, Okolie H, Crossey MJ, VanderJagt DJ. Lipid profiles and trans fatty acids in serum phospholipids of semi-nomadic Fulani in northern Nigeria. J Health Popul Nutr 2010; 28: 159-166
19. Glew RH, Casados JK, Huang YS, Chuang LT, VanderJagt DJ. The fatty acid composition of the serum phospholipids of children with sickle cell disease in Nigeria. Prostaglandins Leukot Essent Fatty Acids 2002; 67: 217-222
20. Hagenfeldt L, Hagenfeldt K, Wennmalm A. Turnover of plasma free arachidonic and oleic acids in men and women. Horm Metab Res 1975; 7: 467-471
21. Hirai K, Kozuki M, Miyanaga K, Miyagawa F, Takezoe R, Hasegawa M, Mori M. Lower levels of eicosapentaenoic acid and the ratio of docosahexaenoic acid to arachidonic acid in sera of patients with multi-infarct dementia. J Clin Biochem Nutr 2005; 36: 83-89
22. Hirai K, Horiuchi R, Ohno Y, Higuchi H, Asano Y. Lower eicosapentaenoic acid and higher arachidonic acid levels in sera of young adults in the Netherlands than in Japan. Environ Health Prev Med 2000; 5: 60-65
23. Hodge AM, Simpson JA, Gibson RA, Sinclair AJ, Makrides M, O'Dea K, English DR, Giles GG. Plasma phospholipid fatty acid composition as a biomarker of habitual dietary fat intake in an ethnically diverse cohort. Nutr Metab Cardiovasc Dis 2007; 17: 415-426
24. Innis SM, Kuhnlein HV, Kinloch D. The composition of red cell membrane phospholipids in Canadian Inuit consuming a diet high in marine mammals. Lipids 1988; 23: 1064-1068
25. Iwamoto M, Imaizumi K, Sato M, Hirooka Y, Sakai K, Takeshita A, Kono M. Serum lipid profiles in Japanese women and men during consumption of walnuts. Eur J Clin Nutr 2002; 56: 629-637
26. Jagannathan SN. Fatty acid composition of adipose tissue in Indian adults: sex difference and influence of pregnancy. Ind J Biochem 1969; 6: 222-225
27. Kale A, Joshi S, Naphade N, Sapkale S, Raju MS, Pillai A, Nasrallah H, Mahadik SP. Opposite changes in predominantly docosahexaenoic acid (DHA) in cerebrospinal fluid and red blood cells from never-medicated first-episode psychotic patients. Schizophr Res 2008; 98: 295-301
28. Karlsson M, Marild S, Brandberg J, Lonn L, Friberg P, Strandvik B. Serum phospholipid fatty acids, adipose tissue, and metabolic markers in obese adolescents. Obesity 2006; 14: 1931-1939
29. Kieu NT, Yasugi E, Hung NT, Kido T, Kondo K, Yamamoto S, Chuyen NV, Oshima M. Serum fatty acids, lipoprotein (a) and apolipoprotein profiles of middle-Aged men and women in South Vietnam. Asia Pac J Clin Nutr 2002; 11: 112-116
30. Kuriki K, Nagaya T, Tokudome Y, Imaeda N, Fujiwara N, Sato J, Goto C, Ikeda M, Maki S, Tajima K, et al. Plasma concentrations of (n-3) highly unsaturated fatty acids are good biomarkers of relative dietary fatty acid intakes: a cross-sectional study. J Nutr 2003; 133: 3643-3650
31. Lee HY, Woo J, Chen ZY, Leung SF, Peng XH. Serum fatty acid, lipid profile and dietary intake of Hong Kong Chinese omnivores and vegetarians. Eur J Clin Nutr 2000; 54: 768-773
32. Lemaitre RN, Siscovick DS, Berry EM, Kark JD, Friedlander Y. Familial aggregation of red blood cell membrane fatty acid composition: the Kibbutzim Family Study. Metabolism 2008; 57: 662-668
33. Lucas M, Dewailly E, Blanchet C, Gingras S, Holub BJ. Plasma omega-3 and psychological distress among Nunavik Inuit (Canada).Psychiatry Res 2009; 167: 266-278
34. Mamalakis G, Kalogeropoulos N, Andrikopoulos N, Hatzis C, Kromhout D, Moschandreas J, Kafatos A. Depression and long chain n-3 fatty acids in adipose tissue in adults from Crete. Eur J Clin Nutr 2006; 60: 882-888
35. Mamalakis G, Kafatos A, Tornaritis M, Alevizos B. Anxiety and adipose essential fatty acid precursors for prostaglandin E1 and E2. J Am Coll Nutr 1998; 17: 239-243
36. McNamara RK, Jandacek R, Rider T, Tso P, Dwivedi Y, Pandey GN. Selective deficits in erythrocyte docosahexaenoic acid composition in adult patients with bipolar disorder and major depressive disorder. J Affect Disord 2010; 126: 303-311
37. Melchert HU, Limsathayourat N, Mihajlovic H, Eichberg J, Thefeld W, Rottka H. Fatty acid patterns in triglycerides, diglycerides, free fatty acids, cholesteryl esters and phosphatidylcholine in serum from vegetarians and non-vegetarians. Atherosclerosis 1987; 65: 159-166
38. Metherel AH, Armstrong JM, Patterson AC, Stark KD. Assessment of blood measures of n-3 polyunsaturated fatty acids with acute fish oil supplementation and washout in men and women. Prostaglandins Leukot Essent Fatty Acids 2009; 81: 23-29
39. Mitchell EA, Lewis S, Cutler DR. Essential fatty acids and maladjusted behaviour in children. Prostaglandins Leukot Med 1983; 12: 281-287
40. Nakamura T, Takebe K, Tando Y, Arai Y, Yamada N, Ishii M, Kikuchi H, Machida K, Imamura K, Terada A. Serum fatty acid composition in normal Japanese and its relationship with dietary fish and vegetable oil contents and blood lipid levels. Ann Nutr Metab 1995; 39: 261-270
41. Nikkari T, Luukkainen P, Pietinen P, Puska P. Fatty acid composition of serum lipid fractions in relation to gender and quality of dietary fat. Ann Med 1995; 27: 491-498
42. Saadatian-Elahi M, Slimani N, Chajes V, Jenab M, Goudable J, Biessy C, Ferrari P, Byrnes G, Autier P, Peeters PH, et al. Plasma phospholipid fatty acid profiles and their association with food intakes: results from a cross-sectional study within the European Prospective Investigation into Cancer and Nutrition. Am J Clin Nutr 2009; 89: 331-346
43. Sfar S, Laporte F, Braham H, Jawed A, Amor S, Kerkeni A. Influence of dietary habits, age and gender on plasma fatty acids levels in a population of healthy Tunisian subjects. Exp Gerontol 2010; 45: 719-725
44. Smit EN, Fokkema MR, Boersma ER, Muskiet FA. Higher erythrocyte 22: 6n-3 and 22: 5n-6, and lower 22: 5n-3 suggest higher delta-4-desaturation capacity in women of childbearing age. Br J Nutr 2003; 89: 739-740
45. Sutherland WH, Shilton ME, Nye ER, Gillies ME, Bakani I, Robertson MC. Urban/rural differences in red blood cell fatty acid composition, plasma lipids and diet in Melanesian Fijians. Eur J Clin Nutr 1995; 49: 233-241
46. Takita T, Nakamura K, Kimira M, Yamada N, Kobayashi Y, Innami S. Serum fatty acid compositions and lipid concentrations and their correlations. J Clin Biochem Nutr 1996; 20: 149-159
47. Tavendale R, Lee AJ, Smith WC, Tunstall-Pedoe H. Adipose tissue fatty acids in Scottish men and women: results from the Scottish Heart Health Study. Atherosclerosis 1992; 94: 161-169
48. Tjønneland A, Overvad K, Thorling E, Ewertz M. Adipose tissue fatty acids as biomarkers of dietary exposure in Danish men and women. Am J Clin Nutr 1993; 57: 629-633
49. Umemura U, Ishimori M, Kobayashi T, Tamura Y, Koike KA, Shimamoto T. Possible effects of diets on serum lipids, fatty acids and blood pressure levels in male and female Japanese university students. Environ Health Prev Med 2005; 10: 42-47
50. Vallés J, Aznar J, Santos MT. Composition of platelet fatty acids and their modulation by plasma fatty acids in humans: effect of age and sex. Atherosclerosis 1988; 71: 215-225
51. Warensjö E, Ohrvall M, Vessby B. Fatty acid composition and estimated desaturase activities are associated with obesity and lifestyle variables in men and women. Nutr Metab Cardiovasc Dis 2006; 16: 128-136
52. Wennberg M, Bergdahl IA, Hallmans G, Norberg M, Lundh T, Skerfving S, Strömberg U, Vessby B, Jansson JH. Fish consumption and myocardial infarction: a second prospective biomarker study from northern Sweden. Am J Clin Nutr 2011; 93: 27-36
53. Wennberg M, Bergdahl IA, Stegmayr B, Hallmans G, Lundh T, Skerfving S, Strömberg U, Vessby B, Jansson JH. Fish intake, mercury, long-chain n-3 polyunsaturated fatty acids and risk of stroke in northern Sweden. Br J Nutr 2007; 98: 1038-1045
54. Yamada T, Strong JP, Ishii T, Ueno T, Koyama M, Wagayama H, Shimizu A, Sakai T, Malcom GT, Guzman MA. Atherosclerosis and omega-3 fatty acids in the populations of a fishing village and a farming village in Japan. Atherosclerosis 2000; 153: 469-481
55. Yeh LL, Kuller LH, Bunker CH, Ukoli FA, Huston SL, Terrell DF. The role of socioeconomic status and serum fatty acids in the relationship between intake of animal foods and cardiovascular risk factors. Ann Epidemiol 1996; 6: 290-298
56. Meyer BJ. Are we consuming enough long chain omega-3 polyunsaturated fatty acids for optimal health?. Prostaglandins Leukot Essent Fatty Acids 2011; 85: 275-280
57. Childs CE, Roume-Nadal, Burdge GC, Calder PC. Gender differences in the n-3 fatty acid content of tissues. Proc Nutr Soc 2008; 67: 19-27
58. Extier A, Langelier B, Perruchot MH, Guesnet P, Van Veldhoven PP, Lavialle M, Alessandri JM. Gender affects liver desaturase expression in a rat model of n-3 fatty acid repletion. J Nutr Biochem 2010; 21: 180-1
59. Pawlosky R, Hibbeln J, Lin Y, Salem N Jr. n-3 fatty acid metabolism in women. Br J Nutr 2003; 90: 993-995
60. Arab L, Akbar J. Biomarkers and the measurement of fatty acids. Public Health Nutr 2002; 5: 865-871
61. Ma J, Folsom AR, Shahar E, Eckfeldt JH. Plasma fatty acid composition as an indicator of habitual dietary fat intake in middleaged adults. Am J Clin Nutr 1995; 62: 564-571
62. Katan MB, Van Birgelen A, Deslypere JP, Penders M, Van Staveren WA. Biological markers of dietary intake, with emphasis on fatty acids. Ann Nutr Metab 1991; 35: 249-252
63. Glatz JF, Soffers AE, Katan MB. Fatty acid composition of serum cholesteryl esters and erythrocyte membranes as indicators of linoleic acid intake in man. Am J Clin Nutr 1989; 49: 269-276
64. Plakké T, Berkel J, Beynen AC, Hermus RJ, Katan MB. Relationship between the fatty acid composition of the diet and that of the subcutaneous adipose tissue in individual human subjects. Hum Nutr Appl Nutr 1983; 37: 365-372
65. Beynen AC, Hermus RJ, Hautvast JG. A mathematical relationship between the fatty acid composition of the diet and that of the adipose tissue in man. Am J Clin Nutr 1980; 33: 81-85