-
1
-
-
2342466734
-
Global prevalence of diabetes: estimates for the year 2000 and projections for 2030
-
Wild S, Roglic G, Green A, Sicree R, King H, (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27: 1047-1053.
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
2
-
-
0018184054
-
The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin
-
Rinderknecht E, Humbel RE, (1978) The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. J Biol Chem 253: 2769-2776.
-
(1978)
J Biol Chem
, vol.253
, pp. 2769-2776
-
-
Rinderknecht, E.1
Humbel, R.E.2
-
3
-
-
0023276184
-
Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults
-
Guler HP, Zapf J, Froesch ER, (1987) Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults. N Engl J Med 317: 137-140.
-
(1987)
N Engl J Med
, vol.317
, pp. 137-140
-
-
Guler, H.P.1
Zapf, J.2
Froesch, E.R.3
-
4
-
-
20444454294
-
The growth hormone hypothesis - 2005 revision
-
Frystyk J, (2005) The growth hormone hypothesis- 2005 revision. Horm Metab Res 37Suppl 1: 44-48.
-
(2005)
Horm Metab Res
, vol.37
, pp. 44-48
-
-
Frystyk, J.1
-
5
-
-
0022538474
-
Protein kinase activity of the insulin receptor
-
Gammeltoft S, Van Obberghen E, (1986) Protein kinase activity of the insulin receptor. Biochem J 235: 1-11.
-
(1986)
Biochem J
, vol.235
, pp. 1-11
-
-
Gammeltoft, S.1
van Obberghen, E.2
-
6
-
-
33244464562
-
Critical nodes in signalling pathways: insights into insulin action
-
Taniguchi CM, Emanuelli B, Kahn CR, (2006) Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 7: 85-96.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 85-96
-
-
Taniguchi, C.M.1
Emanuelli, B.2
Kahn, C.R.3
-
7
-
-
0014682321
-
Production and excretion of hydrogen gas in man
-
Levitt MD, (1969) Production and excretion of hydrogen gas in man. N Engl J Med 281: 122-127.
-
(1969)
N Engl J Med
, vol.281
, pp. 122-127
-
-
Levitt, M.D.1
-
8
-
-
80054910098
-
How to interpret hydrogen breath tests
-
Ghoshal UC, (2011) How to interpret hydrogen breath tests. J Neurogastroenterol Motil 17: 312-317.
-
(2011)
J Neurogastroenterol Motil
, vol.17
, pp. 312-317
-
-
Ghoshal, U.C.1
-
9
-
-
0034890442
-
Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation
-
Gharib B, Hanna S, Abdallahi OM, Lepidi H, Gardette B, et al. (2001) Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation. C R Acad Sci III 324: 719-724.
-
(2001)
C R Acad Sci III
, vol.324
, pp. 719-724
-
-
Gharib, B.1
Hanna, S.2
Abdallahi, O.M.3
Lepidi, H.4
Gardette, B.5
-
10
-
-
34250021071
-
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals
-
Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, et al. (2007) Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 13: 688-694.
-
(2007)
Nat Med
, vol.13
, pp. 688-694
-
-
Ohsawa, I.1
Ishikawa, M.2
Takahashi, K.3
Watanabe, M.4
Nishimaki, K.5
-
11
-
-
61449159621
-
Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease
-
Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, et al. (2009) Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease. Neurosci Lett 453: 81-85.
-
(2009)
Neurosci Lett
, vol.453
, pp. 81-85
-
-
Fu, Y.1
Ito, M.2
Fujita, Y.3
Ito, M.4
Ichihara, M.5
-
12
-
-
56349087883
-
Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice
-
Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S, (2008) Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. Biochem Biophys Res Commun 377: 1195-1198.
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 1195-1198
-
-
Ohsawa, I.1
Nishimaki, K.2
Yamagata, K.3
Ishikawa, M.4
Ohta, S.5
-
13
-
-
70349705530
-
Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, et al. (2009) Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. PLoS One 4: e7247.
-
(2009)
PLoS One
, vol.4
-
-
Fujita, K.1
Seike, T.2
Yutsudo, N.3
Ohno, M.4
Yamada, H.5
-
14
-
-
77649193005
-
Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats
-
Chen H, Sun YP, Li Y, Liu WW, Xiang HG, et al. (2010) Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats. Biochem Biophys Res Commun 393: 308-313.
-
(2010)
Biochem Biophys Res Commun
, vol.393
, pp. 308-313
-
-
Chen, H.1
Sun, Y.P.2
Li, Y.3
Liu, W.W.4
Xiang, H.G.5
-
15
-
-
70349748784
-
Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells
-
Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, et al. (2009) Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells. Biochem Biophys Res Commun 389: 651-656.
-
(2009)
Biochem Biophys Res Commun
, vol.389
, pp. 651-656
-
-
Itoh, T.1
Fujita, Y.2
Ito, M.3
Masuda, A.4
Ohno, K.5
-
16
-
-
79959655309
-
Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice
-
Kamimura N, Nishimaki K, Ohsawa I, Ohta S, (2011) Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice. Obesity (Silver Spring) 19: 1396-1403.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 1396-1403
-
-
Kamimura, N.1
Nishimaki, K.2
Ohsawa, I.3
Ohta, S.4
-
17
-
-
41349120002
-
Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance
-
Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, et al. (2008) Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res 28: 137-143.
-
(2008)
Nutr Res
, vol.28
, pp. 137-143
-
-
Kajiyama, S.1
Hasegawa, G.2
Asano, M.3
Hosoda, H.4
Fukui, M.5
-
18
-
-
0030572883
-
Comparison of isoproterenol with BRL37344 in activation of beta 3-adrenoceptors to inhibit the uptake of [14C]deoxy-D-glucose and translocation of glucose transporter (GLUT4) to membrane fraction in rat adipocytes
-
Chang CJ, Kao JT, Lee TL, Lai CW, Cheng JT, (1996) Comparison of isoproterenol with BRL37344 in activation of beta 3-adrenoceptors to inhibit the uptake of [14C]deoxy-D-glucose and translocation of glucose transporter (GLUT4) to membrane fraction in rat adipocytes. J Auton Nerv Syst 61: 191-194.
-
(1996)
J Auton Nerv Syst
, vol.61
, pp. 191-194
-
-
Chang, C.J.1
Kao, J.T.2
Lee, T.L.3
Lai, C.W.4
Cheng, J.T.5
-
19
-
-
0024229140
-
Diet-induced type II diabetes in C57BL/6J mice
-
Surwit RS, Kuhn CM, Cochrane C, McCubbin JA, Feinglos MN, (1988) Diet-induced type II diabetes in C57BL/6J mice. Diabetes 37: 1163-1167.
-
(1988)
Diabetes
, vol.37
, pp. 1163-1167
-
-
Surwit, R.S.1
Kuhn, C.M.2
Cochrane, C.3
McCubbin, J.A.4
Feinglos, M.N.5
-
20
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, et al. (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
-
21
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, et al. (1996) Abnormal splicing of the leptin receptor in diabetic mice. Nature 379: 632-635.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
-
22
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, et al. (1996) Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84: 491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
-
23
-
-
78751662679
-
Type 1 diabetes: etiology, immunology, and therapeutic strategies
-
van Belle TL, Coppieters KT, von Herrath MG, (2011) Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol Rev 91: 79-118.
-
(2011)
Physiol Rev
, vol.91
, pp. 79-118
-
-
van Belle, T.L.1
Coppieters, K.T.2
von Herrath, M.G.3
-
24
-
-
84872253042
-
Noninsulin pharmacological management of type 1 diabetes mellitus
-
Garg V, (2011) Noninsulin pharmacological management of type 1 diabetes mellitus. Indian J Endocrinol Metab 15: S5-S11.
-
(2011)
Indian J Endocrinol Metab
, vol.15
-
-
Garg, V.1
-
25
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S, Finkel T, (2005) Mitochondria, oxidants, and aging. Cell 120: 483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
26
-
-
14644442283
-
Oxygen, oxidative stress, hypoxia, and heart failure
-
Giordano FJ, (2005) Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Invest 115: 500-508.
-
(2005)
J Clin Invest
, vol.115
, pp. 500-508
-
-
Giordano, F.J.1
-
27
-
-
0036086130
-
Free radicals in the physiological control of cell function
-
Droge W, (2002) Free radicals in the physiological control of cell function. Physiol Rev 82: 47-95.
-
(2002)
Physiol Rev
, vol.82
, pp. 47-95
-
-
Droge, W.1
-
28
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance B, Sies H, Boveris A, (1979) Hydroperoxide metabolism in mammalian organs. Physiol Rev 59: 527-605.
-
(1979)
Physiol Rev
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
29
-
-
77949869116
-
Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study
-
Nakao A, Toyoda Y, Sharma P, Evans M, Guthrie N, (2010) Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. J Clin Biochem Nutr 46: 140-149.
-
(2010)
J Clin Biochem Nutr
, vol.46
, pp. 140-149
-
-
Nakao, A.1
Toyoda, Y.2
Sharma, P.3
Evans, M.4
Guthrie, N.5
-
30
-
-
77953903866
-
Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release
-
Xie K, Yu Y, Pei Y, Hou L, Chen S, et al. (2010) Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release. Shock 34: 90-97.
-
(2010)
Shock
, vol.34
, pp. 90-97
-
-
Xie, K.1
Yu, Y.2
Pei, Y.3
Hou, L.4
Chen, S.5
-
31
-
-
0024394697
-
The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid
-
Aruoma OI, Halliwell B, Hoey BM, Butler J, (1989) The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radic Biol Med 6: 593-597.
-
(1989)
Free Radic Biol Med
, vol.6
, pp. 593-597
-
-
Aruoma, O.I.1
Halliwell, B.2
Hoey, B.M.3
Butler, J.4
-
32
-
-
0030474051
-
Thiol regulation of endotoxin-induced release of tumour necrosis factor alpha from isolated rat Kupffer cells
-
Neuschwander-Tetri BA, Bellezzo JM, Britton RS, Bacon BR, Fox ES, (1996) Thiol regulation of endotoxin-induced release of tumour necrosis factor alpha from isolated rat Kupffer cells. Biochem J 320 (Pt 3): 1005-1010.
-
(1996)
Biochem J
, vol.320
, Issue.Pt 3
, pp. 1005-1010
-
-
Neuschwander-Tetri, B.A.1
Bellezzo, J.M.2
Britton, R.S.3
Bacon, B.R.4
Fox, E.S.5
-
33
-
-
0347758406
-
Evidence that glutathione depletion is a mechanism responsible for the anti-inflammatory effects of ethyl pyruvate in cultured lipopolysaccharide-stimulated RAW 264.7 cells
-
Song M, Kellum JA, Kaldas H, Fink MP, (2004) Evidence that glutathione depletion is a mechanism responsible for the anti-inflammatory effects of ethyl pyruvate in cultured lipopolysaccharide-stimulated RAW 264.7 cells. J Pharmacol Exp Ther 308: 307-316.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 307-316
-
-
Song, M.1
Kellum, J.A.2
Kaldas, H.3
Fink, M.P.4
-
34
-
-
0032039959
-
Clinical applications of N-acetylcysteine
-
Kelly GS, (1998) Clinical applications of N-acetylcysteine. Altern Med Rev 3: 114-127.
-
(1998)
Altern Med Rev
, vol.3
, pp. 114-127
-
-
Kelly, G.S.1
-
35
-
-
0032841575
-
N-acetylcysteine, a cancer chemopreventive agent, causes oxidative damage to cellular and isolated DNA
-
Oikawa S, Yamada K, Yamashita N, Tada-Oikawa S, Kawanishi S, (1999) N-acetylcysteine, a cancer chemopreventive agent, causes oxidative damage to cellular and isolated DNA. Carcinogenesis 20: 1485-1490.
-
(1999)
Carcinogenesis
, vol.20
, pp. 1485-1490
-
-
Oikawa, S.1
Yamada, K.2
Yamashita, N.3
Tada-Oikawa, S.4
Kawanishi, S.5
-
36
-
-
0036521856
-
Antioxidant and pro-oxidant effect of the thiolic compounds N-acetyl-L-cysteine and glutathione against free radical-induced lipid peroxidation
-
Sagrista ML, Garcia AE, Africa De Madariaga M, Mora M, (2002) Antioxidant and pro-oxidant effect of the thiolic compounds N-acetyl-L-cysteine and glutathione against free radical-induced lipid peroxidation. Free Radic Res 36: 329-340.
-
(2002)
Free Radic Res
, vol.36
, pp. 329-340
-
-
Sagrista, M.L.1
Garcia, A.E.2
Africa de Madariaga, M.3
Mora, M.4
-
37
-
-
33745845821
-
Quantitative measurement of hydroxyl radical induced DNA double-strand breaks and the effect of N-acetyl-L-cysteine
-
Su M, Yang Y, Yang G, (2006) Quantitative measurement of hydroxyl radical induced DNA double-strand breaks and the effect of N-acetyl-L-cysteine. FEBS Lett 580: 4136-4142.
-
(2006)
FEBS Lett
, vol.580
, pp. 4136-4142
-
-
Su, M.1
Yang, Y.2
Yang, G.3
-
38
-
-
33644614521
-
A dual effect of N-acetylcysteine on acute ethanol-induced liver damage in mice
-
Wang AL, Wang JP, Wang H, Chen YH, Zhao L, et al. (2006) A dual effect of N-acetylcysteine on acute ethanol-induced liver damage in mice. Hepatol Res 34: 199-206.
-
(2006)
Hepatol Res
, vol.34
, pp. 199-206
-
-
Wang, A.L.1
Wang, J.P.2
Wang, H.3
Chen, Y.H.4
Zhao, L.5
-
39
-
-
0035884859
-
Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise
-
Childs A, Jacobs C, Kaminski T, Halliwell B, Leeuwenburgh C, (2001) Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise. Free Radic Biol Med 31: 745-753.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 745-753
-
-
Childs, A.1
Jacobs, C.2
Kaminski, T.3
Halliwell, B.4
Leeuwenburgh, C.5
-
40
-
-
0020508747
-
Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases
-
Ames BN, (1983) Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science 221: 1256-1264.
-
(1983)
Science
, vol.221
, pp. 1256-1264
-
-
Ames, B.N.1
-
41
-
-
0024239038
-
Antioxidant defenses and lipid peroxidation in human blood plasma
-
Frei B, Stocker R, Ames BN, (1988) Antioxidant defenses and lipid peroxidation in human blood plasma. Proc Natl Acad Sci U S A 85: 9748-9752.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 9748-9752
-
-
Frei, B.1
Stocker, R.2
Ames, B.N.3
-
42
-
-
0029868538
-
Vitamin C-driven free radical generation from iron
-
Herbert V, Shaw S, Jayatilleke E, (1996) Vitamin C-driven free radical generation from iron. J Nutr 126: 1213S-1220S.
-
(1996)
J Nutr
, vol.126
-
-
Herbert, V.1
Shaw, S.2
Jayatilleke, E.3
-
43
-
-
0030024893
-
Ascorbyl radical formation in patients with sepsis: effect of ascorbate loading
-
Galley HF, Davies MJ, Webster NR, (1996) Ascorbyl radical formation in patients with sepsis: effect of ascorbate loading. Free Radic Biol Med 20: 139-143.
-
(1996)
Free Radic Biol Med
, vol.20
, pp. 139-143
-
-
Galley, H.F.1
Davies, M.J.2
Webster, N.R.3
-
44
-
-
77950901103
-
Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure
-
Tanno M, Kuno A, Yano T, Miura T, Hisahara S, et al. (2010) Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure. J Biol Chem 285: 8375-8382.
-
(2010)
J Biol Chem
, vol.285
, pp. 8375-8382
-
-
Tanno, M.1
Kuno, A.2
Yano, T.3
Miura, T.4
Hisahara, S.5
-
45
-
-
61849121847
-
Apoptotic signaling induced by H2O2-mediated oxidative stress in differentiated C2C12 myotubes
-
Siu PM, Wang Y, Alway SE, (2009) Apoptotic signaling induced by H2O2-mediated oxidative stress in differentiated C2C12 myotubes. Life Sci 84: 468-481.
-
(2009)
Life Sci
, vol.84
, pp. 468-481
-
-
Siu, P.M.1
Wang, Y.2
Alway, S.E.3
-
46
-
-
84857672123
-
Antioxidant and Hepatoprotective Effects of the Red Ginseng Essential Oil in H(2)O(2)-Treated HepG2 Cells and CCl(4)-Treated Mice
-
Bak MJ, Jun M, Jeong WS, (2012) Antioxidant and Hepatoprotective Effects of the Red Ginseng Essential Oil in H(2)O(2)-Treated HepG2 Cells and CCl(4)-Treated Mice. Int J Mol Sci 13: 2314-2330.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 2314-2330
-
-
Bak, M.J.1
Jun, M.2
Jeong, W.S.3
-
47
-
-
0025373728
-
Glucose transport and glucose transporters in muscle and their metabolic regulation
-
Klip A, Paquet MR, (1990) Glucose transport and glucose transporters in muscle and their metabolic regulation. Diabetes Care 13: 228-243.
-
(1990)
Diabetes Care
, vol.13
, pp. 228-243
-
-
Klip, A.1
Paquet, M.R.2
-
48
-
-
0017759258
-
Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle
-
Yaffe D, Saxel O, (1977) Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. Nature 270: 725-727.
-
(1977)
Nature
, vol.270
, pp. 725-727
-
-
Yaffe, D.1
Saxel, O.2
-
49
-
-
0036288402
-
Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states
-
Farese RV, (2002) Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states. Am J Physiol Endocrinol Metab 283: E1-11.
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
, pp. 1-11
-
-
Farese, R.V.1
-
50
-
-
80052511813
-
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
-
Mihaylova MM, Shaw RJ, (2011) The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat Cell Biol 13: 1016-1023.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1016-1023
-
-
Mihaylova, M.M.1
Shaw, R.J.2
-
51
-
-
33947596679
-
The GLUT4 glucose transporter
-
Huang S, Czech MP, (2007) The GLUT4 glucose transporter. Cell Metab 5: 237-252.
-
(2007)
Cell Metab
, vol.5
, pp. 237-252
-
-
Huang, S.1
Czech, M.P.2
-
52
-
-
0037189548
-
Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport
-
Chen HC, Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert M, et al. (2002) Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport. J Biol Chem 277: 23554-23562.
-
(2002)
J Biol Chem
, vol.277
, pp. 23554-23562
-
-
Chen, H.C.1
Bandyopadhyay, G.2
Sajan, M.P.3
Kanoh, Y.4
Standaert, M.5
-
53
-
-
0028657016
-
Treatment of cultured pancreatic B-cells with streptozotocin induces cell death by apoptosis
-
Morgan NG, Cable HC, Newcombe NR, Williams GT, (1994) Treatment of cultured pancreatic B-cells with streptozotocin induces cell death by apoptosis. Biosci Rep 14: 243-250.
-
(1994)
Biosci Rep
, vol.14
, pp. 243-250
-
-
Morgan, N.G.1
Cable, H.C.2
Newcombe, N.R.3
Williams, G.T.4
-
54
-
-
0029257151
-
Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotozin contributes to islet cell DNA damage
-
Kroncke KD, Fehsel K, Sommer A, Rodriguez ML, Kolb-Bachofen V, (1995) Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotozin contributes to islet cell DNA damage. Biol Chem Hoppe Seyler 376: 179-185.
-
(1995)
Biol Chem Hoppe Seyler
, vol.376
, pp. 179-185
-
-
Kroncke, K.D.1
Fehsel, K.2
Sommer, A.3
Rodriguez, M.L.4
Kolb-Bachofen, V.5
-
55
-
-
0029556228
-
Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability
-
Delaney CA, Dunger A, Di Matteo M, Cunningham JM, Green MH, et al. (1995) Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability. Biochem Pharmacol 50: 2015-2020.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 2015-2020
-
-
Delaney, C.A.1
Dunger, A.2
Di Matteo, M.3
Cunningham, J.M.4
Green, M.H.5
-
56
-
-
0034434893
-
Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin
-
Elsner M, Guldbakke B, Tiedge M, Munday R, Lenzen S, (2000) Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin. Diabetologia 43: 1528-1533.
-
(2000)
Diabetologia
, vol.43
, pp. 1528-1533
-
-
Elsner, M.1
Guldbakke, B.2
Tiedge, M.3
Munday, R.4
Lenzen, S.5
-
57
-
-
0018090354
-
Insulin receptors are widely distributed in the central nervous system of the rat
-
Havrankova J, Roth J, Brownstein M, (1978) Insulin receptors are widely distributed in the central nervous system of the rat. Nature 272: 827-829.
-
(1978)
Nature
, vol.272
, pp. 827-829
-
-
Havrankova, J.1
Roth, J.2
Brownstein, M.3
-
58
-
-
0025612094
-
Localization of insulin receptor mRNA in rat brain by in situ hybridization
-
Marks JL, Porte D Jr, Stahl WL, Baskin DG, (1990) Localization of insulin receptor mRNA in rat brain by in situ hybridization. Endocrinology 127: 3234-3236.
-
(1990)
Endocrinology
, vol.127
, pp. 3234-3236
-
-
Marks, J.L.1
Porte Jr., D.2
Stahl, W.L.3
Baskin, D.G.4
-
59
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
Bruning JC, Gautam D, Burks DJ, Gillette J, Schubert M, et al. (2000) Role of brain insulin receptor in control of body weight and reproduction. Science 289: 2122-2125.
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Bruning, J.C.1
Gautam, D.2
Burks, D.J.3
Gillette, J.4
Schubert, M.5
-
60
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, et al. (1999) Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20: 68-100.
-
(1999)
Endocr Rev
, vol.20
, pp. 68-100
-
-
Kalra, S.P.1
Dube, M.G.2
Pu, S.3
Xu, B.4
Horvath, T.L.5
-
61
-
-
0035430665
-
Ghrelin: an orexigenic and somatotrophic signal from the stomach
-
Inui A, (2001) Ghrelin: an orexigenic and somatotrophic signal from the stomach. Nat Rev Neurosci 2: 551-560.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 551-560
-
-
Inui, A.1
-
62
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz MW, Woods SC, Porte D Jr, Seeley RJ, Baskin DG, (2000) Central nervous system control of food intake. Nature 404: 661-671.
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte Jr., D.3
Seeley, R.J.4
Baskin, D.G.5
-
63
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, et al. (1999) Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402: 656-660.
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
-
64
-
-
0035843183
-
A role for ghrelin in the central regulation of feeding
-
Nakazato M, Murakami N, Date Y, Kojima M, Matsuo H, et al. (2001) A role for ghrelin in the central regulation of feeding. Nature 409: 194-198.
-
(2001)
Nature
, vol.409
, pp. 194-198
-
-
Nakazato, M.1
Murakami, N.2
Date, Y.3
Kojima, M.4
Matsuo, H.5
-
65
-
-
0036892144
-
Role of ghrelin in streptozotocin-induced diabetic hyperphagia
-
Ishii S, Kamegai J, Tamura H, Shimizu T, Sugihara H, et al. (2002) Role of ghrelin in streptozotocin-induced diabetic hyperphagia. Endocrinology 143: 4934-4937.
-
(2002)
Endocrinology
, vol.143
, pp. 4934-4937
-
-
Ishii, S.1
Kamegai, J.2
Tamura, H.3
Shimizu, T.4
Sugihara, H.5
-
66
-
-
33646773565
-
Role of endogenous ghrelin in the hyperphagia of mice with streptozotocin-induced diabetes
-
Dong J, Peeters TL, De Smet B, Moechars D, Delporte C, et al. (2006) Role of endogenous ghrelin in the hyperphagia of mice with streptozotocin-induced diabetes. Endocrinology 147: 2634-2642.
-
(2006)
Endocrinology
, vol.147
, pp. 2634-2642
-
-
Dong, J.1
Peeters, T.L.2
de Smet, B.3
Moechars, D.4
Delporte, C.5
-
67
-
-
10744227324
-
Insulin is required for prandial ghrelin suppression in humans
-
Murdolo G, Lucidi P, Di Loreto C, Parlanti N, De Cicco A, et al. (2003) Insulin is required for prandial ghrelin suppression in humans. Diabetes 52: 2923-2927.
-
(2003)
Diabetes
, vol.52
, pp. 2923-2927
-
-
Murdolo, G.1
Lucidi, P.2
Di Loreto, C.3
Parlanti, N.4
de Cicco, A.5
-
68
-
-
84255199265
-
Central nervous control of energy and glucose balance: focus on the central melanocortin system
-
Xu Y, Elmquist JK, Fukuda M, (2011) Central nervous control of energy and glucose balance: focus on the central melanocortin system. Ann N Y Acad Sci 1243: 1-14.
-
(2011)
Ann N Y Acad Sci
, vol.1243
, pp. 1-14
-
-
Xu, Y.1
Elmquist, J.K.2
Fukuda, M.3
-
69
-
-
0030724591
-
Pathogenesis of type 2 diabetes mellitus: metabolic and molecular implications for identifying diabetes genes
-
RA D, (1997) Pathogenesis of type 2 diabetes mellitus: metabolic and molecular implications for identifying diabetes genes. Diabetes Rev 5: 177-269.
-
(1997)
Diabetes Rev
, vol.5
, pp. 177-269
-
-
-
70
-
-
75149180515
-
Standards of medical care in diabetes-2010
-
American Diabetes A, (2010) Standards of medical care in diabetes-2010. Diabetes Care 33Suppl 1: S11-61.
-
(2010)
Diabetes Care
, vol.33
-
-
American Diabetes, A.1
-
71
-
-
57849094494
-
Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice
-
Nagata K, Nakashima-Kamimura N, Mikami T, Ohsawa I, Ohta S, (2009) Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice. Neuropsychopharmacology 34: 501-508.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 501-508
-
-
Nagata, K.1
Nakashima-Kamimura, N.2
Mikami, T.3
Ohsawa, I.4
Ohta, S.5
-
72
-
-
68149136575
-
Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice
-
Nakashima-Kamimura N, Mori T, Ohsawa I, Asoh S, Ohta S, (2009) Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. Cancer Chemother Pharmacol 64: 753-761.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 753-761
-
-
Nakashima-Kamimura, N.1
Mori, T.2
Ohsawa, I.3
Asoh, S.4
Ohta, S.5
|