A gene regulatory motif that generates oscillatory or multiway switch outputs

Journal of the Royal Society Interface

Volumn 10, Issue 79, 2013, Pages

  Panovska Griffiths, Jasmina ^a,b   Page, Karen M ^b   Briscoe, James ^c  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Gene regulatory network; Morphogen; Multistate switch; Neural tube; Oscillations; Sonic Hedgehog

Indexed keywords

GENES; TISSUE; TOPOLOGY; TRANSCRIPTION FACTORS; TUBES (COMPONENTS);

GENE REGULATORY NETWORKS; MORPHOGEN; MULTI-STATE; NEURAL TUBE; OSCILLATIONS; SONIC HEDGEHOGS;

SWITCHING CIRCUITS;

OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR;

ARTICLE; CONCENTRATION (PARAMETERS); GENE EXPRESSION; GENE INTERACTION; GENE REGULATORY NETWORK; GENE SWITCHING; GENETIC STABILITY; LINEAR SYSTEM; MEMBRANE STRUCTURE; MOLECULAR DYNAMICS; OSCILLATION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; QUALITATIVE ANALYSIS; SIGNAL TRANSDUCTION; STEADY STATE; ANIMAL; BIOLOGICAL MODEL; BIOLOGICAL RHYTHM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEURAL TUBE; PHYSIOLOGY; PRENATAL DEVELOPMENT; SPECIES DIFFERENCE; VERTEBRATE;

ERINACEIDAE; VERTEBRATA;

ANIMALS; BIOLOGICAL CLOCKS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; HEDGEHOG PROTEINS; MODELS, BIOLOGICAL; NEURAL TUBE; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS; VERTEBRATES;

EID: 84872235871     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2012.0826     Document Type: Article

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