Sickle Erythrocytes Target Cytotoxics to Hypoxic Tumor Microvessels and Potentiate a Tumoricidal Response

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Terman, David S ^a   Viglianti, Benjamin L ^b   Zennadi, Rahima ^c   Fels, Diane ^c   Boruta, Richard J ^d   Yuan, Hong ^d   Dreher, Mathew R ^e   Grant, Gerald ^c   Rabbani, Zahid N ^c   Moon, Ejung ^c   Lan, Lan ^c   Eble, Joseph ^f   Cao, Yiting ^c   Sorg, Brian ^g   Ashcraft, Kathleen ^c   Palmer, Greg ^c   Telen, Marilyn J ^c   Dewhirst, Mark W ^c  

^a Molecular Genetics Program Jenomic   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f MAYO CLINIC   (United States)

^g NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD51 ANTIGEN; CELL ADHESION MOLECULE; HEME OXYGENASE; HEMIN; HEMOGLOBIN; HYDROGEN PEROXIDE; LAMININ ALPHA 5; PROTEIN PCAM1; PROTOPORPHYRIN ZINC; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOACCUMULATION; BLOOD VESSEL OCCLUSION; BREAST CARCINOMA; CANCER CELL DESTRUCTION; CELL ADHESION; CELL DAMAGE; CELL HYPOXIA; CELL MEDIATED CYTOTOXICITY; CELL SURVIVAL; CELLULAR DISTRIBUTION; CLONOGENIC ASSAY; CONTROLLED STUDY; ERYTHROCYTE; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MICROVASCULATURE; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; SICKLE CELL; TUMOR CELL; TUMOR VASCULARIZATION;

ANEMIA, SICKLE CELL; ANIMALS; ANOXIA; BLOTTING, WESTERN; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; CYTOTOXICITY, IMMUNOLOGIC; ERYTHROCYTES, ABNORMAL; FEMALE; HEME OXYGENASE-1; HEMIN; HUMANS; HYDROGEN PEROXIDE; IMMUNOTHERAPY, ADOPTIVE; MEMBRANE PROTEINS; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; PROTOPORPHYRINS; REACTIVE OXYGEN SPECIES; TUMOR MICROENVIRONMENT;

EID: 84872231284     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052543     Document Type: Article

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