The L-type Ca2+ Channels Blocker Nifedipine Represses Mesodermal Fate Determination in Murine Embryonic Stem Cells

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Nguemo, Filomain ^a   Fleischmann, Bernd K ^b   Gupta, Manoj K ^a   Šarić, Tomo ^a   Malan, Daniela ^b   Liang, Huamin ^c   Pfannkuche, Kurt ^a   Bloch, Wilhelm ^d   Schunkert, Heribert ^e   Hescheler, Jürgen ^a   Reppel, Michael ^a,e  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

^e UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; CALCIUM CHANNEL L TYPE; CALCIUM ION; ENHANCED GREEN FLUORESCENT PROTEIN; NIFEDIPINE; VERAPAMIL; CALCIUM CHANNEL BLOCKING AGENT; CAV1.2 PROTEIN, MOUSE; GREEN FLUORESCENT PROTEIN; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL LINEAGE; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; EMBRYOID BODY; EMBRYONIC STEM CELL; GENE CONTROL; GENE EXPRESSION; GROWTH INHIBITION; HEART DEVELOPMENT; HEART MUSCLE CELL; IN VITRO STUDY; INCUBATION TIME; MESODERM; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; CALCIUM SIGNALING; CELL LINE; CLASSIFICATION; CYTOLOGY; DOWN REGULATION; DRUG EFFECT; GENETICS; HEART; METABOLISM; PRENATAL DEVELOPMENT;

IPS; MURINAE;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL LINE; DOWN-REGULATION; EMBRYOID BODIES; EMBRYONIC STEM CELLS; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; HEART; INDUCED PLURIPOTENT STEM CELLS; MESODERM; MICE; MYOCYTES, CARDIAC; NIFEDIPINE; RECOMBINANT PROTEINS;

EID: 84872192952     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053407     Document Type: Article

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