Calcium channel blockade in embryonic cardiac progenitor cells disrupts normal cardiac cell differentiation

Stem Cells and Development

Volumn 19, Issue 12, 2010, Pages 1959-1965

  Linask, Kaari L ^a,b   Linask, Kersti K ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; DILTIAZEM; FLUO 3; OMEGA CONOTOXIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL POPULATION; CHICK EMBRYO; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; GASTRULATION; GROWTH INHIBITION; HEART DEVELOPMENT; HEART MUSCLE; HEART MUSCLE CELL; MUSCLE DEVELOPMENT; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL;

ANILINE COMPOUNDS; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM CHANNELS, N-TYPE; CELL DIFFERENTIATION; CHICK EMBRYO; DILTIAZEM; HEART; MICROSCOPY, CONFOCAL; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; OMEGA-CONOTOXINS; STEM CELLS; XANTHENES;

EID: 78649719511     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2010.0192     Document Type: Article

References (35)

1. Kehat I, D Kenyagin-Karsenti, M Snir, H Segev, M Amit, A Gepstein, E Livne, O Binah, J Itskovitz-Eldor and L Gepstein. (2001). Human embryonic stem cells can differentiate into myocytes with structural and functional properties of car-diomyocytes. J Clin Invest 108:407-414.
2. Korhonen T, R Rapila, VP Ronkainen, JT Koivumaki and P Tavi. (2010). Local Ca2\+ releases enable rapid heart rates in developing cardiomyocytes. J Physiol 588:1407-1417.
3. Satin J, I Itzhaki, S Rapoport, EA Schroder, L Izu, G Arbel, R Beyar, CW Balke, J Schiller and L Gepstein. (2008). Calcium handling in human embryonic stem cell-derived cardio-myocytes. Stem Cells 26:1961-1972.
4. Sedam O, K Dolnikov, N Zeevi-Levin, N Leibovich, M Amit, J Itskovitz-Eldor and O Binah. (2008). 1,4,5-Inositol triphos-phate-operated intracellular Ca2\+ stores and angiotensin-II= endothelin-1 signaling pathway are functional in human embryonic stem cell-derived cardiomyocytes. Stem Cells 26:3130-3138.
5. Linask KK and YH Gui. (1995). Inhibitory effects of ouabain on early heart development and cardiomyogenesis in the chick embryo. Dev Dynamics 203:93-105.
6. Linask KK, MD Han, M Artman and CA Ludwig. (2001). Sodium-calcium exchanger (NCX-1) and calcium modulation. NCX protein expression patterns and regulation of early heart development. Dev Dynamics 221:249-264.
7. Koushik SV, J Wang, R Rogers, D Moskophidis, NA Lambert, RL Creazzo and SJ Conway. (2001). Targeted inacti-vation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization. FASEB J 15:1209-1211.
8. Hamburger V and H Hamilton. (1951). Series of embryonic chicken growth. J Morphology 88:49-92.
9. Linask KK and JW Lash. (1988). A role for fibronectin in the migration of avian precardiac cells. I. Dose dependent effects of fibronectin antibody. Dev Biol 129:315-323.
10. Cai CL, X Liang, Y Shi, PH Chu, SL Pfaff, J Chen and S Evans. (2003). Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell 5:877-889.
11. Linask K. (2003). Regulation of heart morphology: current molecular and cellular perspectives on the coordinated emergence of cardiac form and function. Birth Defects Res C 69:14-24.
12. Bixby JL, GB Grunwald and RJ Bookman. (1994). Ca influx and neurite growth in response to purified N-cadherin and laminin. J Cell Biol 127:1461-1475.
13. Lampidis T, D Kolonias, N Savaraj and R Rubin. (1992). Cardiostimulatory and antiarrhythmic activity of tubulin-binding agents. Proc Natl Acad Sci USA 89:1256-1260.
14. Linask KK and T Tsuda. (2000). Application of plastic embedding for sectioning whole-mount immunostained early vertebrate embryos. In: Developmental Biology Protocols. Tuan RS and CW Lo, eds. Humana, Totowa, NJ, pp 165-173.
15. Linask KK. (2003). Regulation of heart morphology: current molecular and cellular perspectives on the coordinated emergence of cardiac form and function. Birth Defects Res C Embryo Today 69:14-24.
16. deDiego C, F Chen, L Xie, A Dave, M Thu, C Rongey, J Weiss and M Valderrabano. (2008). Cardiac alternans in embryonic mouse ventricles. Am J Physiol Heart Circ Physiol 294:H433-H440.
17. Koivumaki JT, J Takalo, T Korhonen, P Tavi and M Weck-strom. (2009). Modelling sarcoplasmic reticulum calcium ATPase and its regulation in cardiac myocytes. Philos Transact A Math Phys Eng Sci 367:2181-2202.
18. Itzhaki I, J Schiller, R Beyar, J Satin and L Gepstein. (2006). Calcium handling in embryonic stem cell-derived cardiac myocytes: of mice and men. Ann N Y Acad Sci 1080:207-215.
19. Passier R and C Mummery. (2003). Origin and use of embryonic and adult stem cells in differentiation and tissue repair. Cardiovasc Res 58:324-335.
20. 2\+-mobilizing receptors of gastrulating chick embryo. Comp Biochem Physiol 97C:9-12.
21. Linask KK. (1992). N-cadherin localization in early heart development and polar expression of Na, K-ATPase, and integrin during pericardial coelom formation and epitheli-alization of the differentiating myocardium. Dev Biol 151:213-224.
22. Linask KK, KA Knudsen and YH Gui. (1997). N-cadherin-catenin interaction: necessary component of cardiac cell compartmentalization during early vertebrate heart development. Dev Biol 185:148-164.
23. Porter GJ, R Makuck and S Rivkees. (2003). Intracellular calcium plays an essential role in cardiac development. Dev Dyn 227:280-290.
24. Hove JR, RW Koster, AS Forouhar, G Acevedo-Bolton, SE Fraser and M Gharib. (2003). Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis. Nature 142:172-177.
25. Stein G, M Srivastava, H Merker and D Neubert. (1990). Effects of calcium channel blockers on the development of early rat postimplantation embryos in culture. Arch Toxicol 64:623-638.
26. Manisastry SM, M Han and KK Linask. (2006). Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development. Dev Dyn 235:2160-2174.
27. Klein PS and DA Melton. (1996). A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci USA 93:8455-8459.
28. Kwon C, KR Cordes and D Srivastava. (2008). Wnt=beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis. Cell Cycle 7:3815-3818.
29. Ueno S, G Weidinger, T Osugi, AD Kohn, JL Golob, L Pabon, H Reinecke, RT Moon and CE Murry. (2007). Biphasic role for Wnt=beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells. Proc Natl Acad Sci USA 104:9685-9690.
30. Foley AC and M Mercola. (2005). Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex. Genes Dev 19:387-396.
31. Qin Y, L Lin, W Pan and D Wu. (2009). Regulation of phosphatidylinositol kinases and metabolism by Wnt3A and Dvl. J Biol Chem 284:22544-22548.
32. Nagy, II, A Railo, R Rapila, T Hast, R Sormunen, P Tavi, J Rasanen and SJ Vainio. (2010). Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression. Cardiovasc Res 85:100-109.
33. Pandur P, M Lasche, L Eisenberg and M Kuhl. (2002). Wnt-11 activation of a non-canonical Wnt signaling pathway is required for cardiogenesis. Nature 418:636-641.
34. Sheldahl LC, DC Slusarski, P Pandur, JR Miller, M Kuhl and RT Moon. (2003). Dishevelled activates Ca2\+ flux, PKC, and CamKII in vertebrate embryos. J Cell Biol 161:769-777.
35. Linask K, YH Gui, R Rasheed and L Kwon. (1992). Pattern development during pericardial coelom formation and specification of the cardiomyocyte cell population by N-cadherin and the Drosophila armadillo protein homologue in the early chick embryo. Mol Biol Cell 3 (Suppl.):206A.