Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: A model of spondylocostal dysostosis and spondylothoracic dysostosis

Bone

Volumn 53, Issue 1, 2013, Pages 248-258

  Makino, Yuji ^a,b   Takahashi, Yu ^c   Tanabe, Rieko ^d   Tamamura, Yoshihiro ^a   Watanabe, Takashi ^a   Haraikawa, Mayu ^d   Hamagaki, Miwako ^a   Hata, Kenji ^e   Kanno, Jun ^c   Yoneda, Toshiyuki ^e   Saga, Yumiko ^f   Goseki Sone, Masae ^d   Kaneko, Kazuo ^b   Yamaguchi, Akira ^a   Iimura, Tadahiro ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d JAPAN WOMEN'S UNIVERSITY   (Japan)

^e OSAKA UNIVERSITY   (Japan)

^f National Institute of Genetics and Department of Genetics   (Japan)

Author keywords

Skeletal development; Spondylocostal dysostosis; Spondylothoracic dysostosis; The segmentation clock; Vertebrae

Indexed keywords

BONE MORPHOGENETIC PROTEIN; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; BONE RADIOGRAPHY; BONE TISSUE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DYSOSTOSIS; EXTRACELLULAR MATRIX; FETUS; GENE; GENE LOSS; GROWTH RATE; HISTOPATHOLOGY; IMAGE ANALYSIS; IMMUNOFLUORESCENCE TEST; IN SITU HYBRIDIZATION; JARCHO LEVIN SYNDROME; MESP2 GENE; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; SPATIOTEMPORAL DISORDER; SPINE DISEASE; SPONDYLOTHORACIC DYSOSTOSIS; THREE DIMENSIONAL IMAGING; VERTEBRA BODY;

ABNORMALITIES, MULTIPLE; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE AND BONES; CONTRACTURE; DISEASE MODELS, ANIMAL; DYSOSTOSES; FLUORESCENT ANTIBODY TECHNIQUE; HEART DEFECTS, CONGENITAL; HERNIA, DIAPHRAGMATIC; MICE; MICE, KNOCKOUT; OSTEOCHONDRODYSPLASIAS; RIBS; SPINE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84872186104     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2012.11.033     Document Type: Article

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