Tgfbr2 regulates the maintenance of boundaries in the axial skeleton

Developmental Biology

Volumn 296, Issue 2, 2006, Pages 363-374

  Baffi, Michael O ^a   Moran, Molly A ^a   Serra, Rosa ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Axial skeleton; Pax; Sclerotome; TGF

Indexed keywords

COLLAGEN TYPE 2; FIBROMODULIN; PEANUT AGGLUTININ; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR PAX1; TRANSCRIPTION FACTOR PAX9; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BONE DEFECT; BONE DEVELOPMENT; BONE MASS; CELL FUNCTION; CELL PROLIFERATION; CHONDROGENESIS; COLLAGEN SYNTHESIS; CONTROLLED STUDY; EMBRYO; FEMALE; GENE DELETION; INTERVERTEBRAL DISK; MALE; MORPHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SCLEROTOME; SIGNAL TRANSDUCTION; STAINING; VERTEBRA BODY; VERTEBRA MALFORMATION;

ARACHIS HYPOGAEA;

EID: 33746885172     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2006.06.002     Document Type: Article

References (51)

1. Baffi M.O., Slattery E., Sohn P., Moses H.L., Chytil A., and Serra R. Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones. Dev. Biol. 276 (2004) 124-142
2. Bagnall K.M., and Sanders E.J. The binding pattern of peanut lectin associated with sclerotome migration and the formation of the vertebral axis in the chick embryo. Anat. Embryol. (Berl.) 180 (1989) 505-513
3. Bagnall K.M., Sanders E.J., and Berdan R.C. Communication compartments in the axial mesoderm of the chick embryo. Anat. Embryol. (Berl.) 186 (1992) 195-204
4. Balling R., Helwig U., Nadeau J., Neubuser A., Schmahl W., and Imai K. Pax genes and skeletal development. Ann. N. Y. Acad. Sci. 785 (1996) 27-33
5. Bronner-Fraser M. Mechanisms of neural crest cell migration. BioEssays 15 (1993) 221-230
6. Bronner-Fraser M., and Stern C. Effects of mesodermal tissues on avian neural crest cell migration. Dev. Biol. 143 (1991) 213-217
7. Bussen M., Petry M., Schuster-Gossler K., Leitges M., Gossler A., and Kispert A. The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev. 18 (2004) 1209-1221
8. Cancedda R., Cancedda F.D., and Castagnola P. Chondrocyte differentiation. Int. Rev. Cytol. 159 (1995) 265-358
9. Christ B., Huang R., and Wilting J. The development of the avian vertebral column. Anat. Embryol. (Berl.) 202 (2000) 179-194
10. Christ B., Huang R., and Scaal M. Formation and differentiation of the avian sclerotome. Anat. Embryol. (Berl.) 208 (2004) 333-350
11. Chytil A., Magnuson M.A., Wright C.V., and Moses H.L. Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis 32 (2002) 73-75
12. Dabovic B., Chen Y., Colarossi C., Obata H., Zambuto L., Perle M.A., and Rifkin D.B. Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability. J. Cell Biol. 156 (2002) 227-232
13. Delise A.M., and Tuan R.S. Analysis of N-cadherin function in limb mesenchymal chondrogenesis in vitro. Dev. Dyn. 225 (2002) 195-204
14. DeLise A.M., Fischer L., and Tuan R.S. Cellular interactions and signaling in cartilage development. Osteoarthr. Cartil. 8 (2000) 309-334
15. Goldstein R.S., and Kalcheim C. Determination of epithelial half-somites in skeletal morphogenesis. Development 116 (1992) 441-445
16. Henderson D.J., Conway S.J., and Copp A.J. Rib truncations and fusions in the Sp2H mouse reveal a role for Pax3 in specification of the ventro-lateral and posterior parts of the somite. Dev. Biol. 209 (1999) 143-158
17. Huang R., Zhi Q., Neubuser A., Muller T.S., Brand-Saberi B., Christ B., and Wilting J. Function of somite and somitocoele cells in the formation of the vertebral motion segment in avian embryos. Acta Anat. (Basel) 155 (1996) 231-241
18. Huang R., Zhi Q., Brand-Saberi B., and Christ B. New experimental evidence for somite resegmentation. Anat. Embryol. (Berl.) 202 (2000) 195-200
19. Jaakkola E., Crane A.M., Laiho K., Herzberg I., Sims A.M., Bradbury L., Calin A., Brophy S., Kauppi M., Kaarela K., Wordsworth B.P., Tuomilehto J., and Brown M.A. The effect of transforming growth factor beta1 gene polymorphisms in ankylosing spondylitis. Rheumatology (Oxford) 43 (2004) 32-38
20. Johnson J., Rhee J., Parsons S.M., Brown D., Olson E.N., and Rawls A. The anterior/posterior polarity of somites is disrupted in paraxis-deficient mice. Dev. Biol. 229 (2001) 176-187
21. Kraus F., Haenig B., and Kispert A. Cloning and expression analysis of the mouse T-box gene Tbx18. Mech. Dev. 100 (2001) 83-86
22. Leitges M., Neidhardt L., Haenig B., Herrmann B.G., and Kispert A. The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column. Development 127 (2000) 2259-2267
23. Mansouri A., Voss A.K., Thomas T., Yokota Y., and Gruss P. Uncx4.1 is required for the formation of the pedicles and proximal ribs and acts upstream of Pax9. Development 127 (2000) 2251-2258
24. McGaughran J.M., Oates A., Donnai D., Read A.P., and Tassabehji M. Mutations in PAX1 may be associated with Klippel-Feil syndrome. Eur. J. Hum. Genet. 11 (2003) 468-474
25. Mittapalli V.R., Huang R., Patel K., Christ B., and Scaal M. Arthrotome: a specific joint forming compartment in the avian somite. Dev. Dyn. 234 (2005) 48-53
26. Monsoro-Burq A.H. Sclerotome development and morphogenesis: when experimental embryology meets genetics. Int. J. Dev. Biol. 49 (2005) 301-308
27. Monsoro-Burq A.H., Bontoux M., Teillet M.A., and Le Douarin N.M. Heterogeneity in the development of the vertebra. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 10435-10439
28. Monsoro-Burq A.H., Duprez D., Watanabe Y., Bontoux M., Vincent C., Brickell P., and Le Douarin N. The role of bone morphogenetic proteins in vertebral development. Development 122 (1996) 3607-3616
29. Ovchinnikov D.A., Deng J.M., Ogunrinu G., and Behringer R.R. Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice. Genesis 26 (2000) 145-146
30. Paavola L.G., Wilson D.B., and Center E.M. Histochemistry of the developing notochord, perichordal sheath and vertebrae in Danforth's short-tail (sd) and normal C57BL/6 mice. J. Embryol. Exp. Morphol. 55 (1980) 227-245
31. Pelton R.W., Dickinson M.E., Moses H.L., and Hogan B.L.M. In situ hybridization analysis of TGF-β3 RNA expression during mouse development: comparative studies with TGF-b1 and -β2. Development 110 (1990) 600-620
32. Peters H., Doll U., and Niessing J. Differential expression of the chicken Pax-1 and Pax-9 gene: in situ hybridization and immunohistochemical analysis. Dev. Dyn. 203 (1995) 1-16
33. Peters H., Wilm B., Sakai N., Imai K., Maas R., and Balling R. Pax1 and Pax9 synergistically regulate vertebral column development. Development 126 (1999) 5399-5408
34. Poole A.R. The histopathology of ankylosing spondylitis: are there unifying hypotheses?. Am. J. Med. Sci. 316 (1998) 228-233
35. Rufai A., Benjamin M., and Ralphs J.R. The development of fibrocartilage in the rat intervertebral disc. Anat. Embryol. (Berl.) 192 (1995) 53-62
36. Saga Y., and Takeda H. The making of the somite: molecular events in vertebrate segmentation. Nat. Rev., Genet. 2 (2001) 835-845
37. Serra R., Johnson M., Filvaroff E.H., LaBorde J., Sheehan D.M., Derynck R., and Moses H.L. Expression of a truncated, kinase-defective TGF-β type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentation and osteoarthritis. J. Cell Biol. 139 (1997) 541-552
38. Smits P., and Lefebvre V. Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs. Development 130 (2003) 1135-1148
39. Sporle R., and Schughart K. Paradox segmentation along inter- and intrasomitic borderlines is followed by dysmorphology of the axial skeleton in the open brain (opb) mouse mutant. Dev. Genet. 22 (1998) 359-373
40. Stern C.D., and Vasiliauskas D. Segmentation: a view from the border. Curr. Top. Dev. Biol. 47 (2000) 107-129
41. Stern C.D., Sisodiya S.M., and Keynes R.J. Interactions between neurites and somite cells: inhibition and stimulation of nerve growth in the chick embryo. J. Embryol. Exp. Morphol. 91 (1986) 209-226
42. Stockdale F.E., Nikovits Jr. W., and Christ B. Molecular and cellular biology of avian somite development. Dev. Dyn. 219 (2000) 304-321
43. Stringa E., and Tuan R.S. Chondrogenic cell subpopulation of chick embryonic calvarium: isolation by peanut agglutinin affinity chromatography and in vitro characterization. Anat. Embryol. (Berl.) 194 (1996) 427-437
44. Tam P.P., and Trainor P.A. Specification and segmentation of the paraxial mesoderm. Anat. Embryol. (Berl.) 189 (1994) 275-305
45. Theiler K. Vertebral malformations. Adv. Anat. Embryol. Cell Biol. 112 (1988) 1-99
46. Tracy M.R., Dormans J.P., and Kusumi K. Klippel-Feil syndrome: clinical features and current understanding of etiology. Clin. Orthop. Relat. Res. (2004) 183-190
47. Walin J., Wilting J., Koseki H., Fritsch R., Christ B., and Balling R. The role of Pax-1 in axial development. Development 120 (1994) 1109-1121
48. Wilkinson D.G., and Nieto M.A. Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts. Methods Enzymol. 225 (1993) 361-373
49. Yamada Y., Okuizumi H., Miyauchi A., Takagi Y., Ikeda K., and Harada A. Association of transforming growth factor beta1 genotype with spinal osteophytosis in Japanese women. Arthritis Rheum. 43 (2000) 452-460
50. Yang X., Chen L., Xu X., Li C., Huang C., and Deng C.X. TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage. J. Cell Biol. 153 (2001) 35-46
51. Zuscik M.J., Baden J.F., Wu Q., Sheu T.J., Schwarz E.M., Drissi H., O'Keefe R.J., Puzas J.E., and Rosier R.N. 5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes. J. Cell Biochem. 92 (2004) 316-331