Acetylated sp1 inhibits PTEN expression through binding to PTEN core promoter and recruitment of HDAC1 and promotes cancer cell migration and invasion

Carcinogenesis

Volumn 34, Issue 1, 2013, Pages 58-67

  Kou, Xiao Xing ^a   Hao, Ting ^a   Meng, Zhen ^a   Zhou, Yan Heng ^a   Gan, Ye Hua ^a  

^a PEKING UNIVERSITY SCHOOL AND HOSPITAL OF STOMATOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE 1; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR SP1;

ACETYLATION; ADENOID CYSTIC CARCINOMA; ANIMAL CELL; ARTICLE; BINDING SITE; CANCER CELL; CANCER CELL CULTURE; CANCER INVASION; CARCINOGENESIS; CELL INVASION; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE MUTATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; LUNG METASTASIS; MALE; METASTASIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN EXPRESSION; SALIVARY GLAND CANCER; SITE DIRECTED MUTAGENESIS; TONGUE CANCER; UPREGULATION;

ACETYLATION; BASE SEQUENCE; CELL LINE; DNA PRIMERS; HISTONE DEACETYLASE 1; HUMANS; MUTAGENESIS, SITE-DIRECTED; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PTEN PHOSPHOHYDROLASE; REAL-TIME POLYMERASE CHAIN REACTION; SP1 TRANSCRIPTION FACTOR;

EID: 84872168313     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs336     Document Type: Article

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