-
1
-
-
0037087324
-
Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors
-
Cunard R, Ricote M, DiCampli D etal. Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors. J Immunol 2002; 1689:2795-2802.
-
(2002)
J Immunol
, vol.1689
, pp. 2795-2802
-
-
Cunard, R.1
Ricote, M.2
DiCampli, D.3
-
2
-
-
0034141545
-
The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses
-
Clark RB, Bishop-Bailey D, Estrada-Hernandez T, Hla T, Puddington L, Padula SJ. The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. J Immunol 2000; 164:1364-1371.
-
(2000)
J Immunol
, vol.164
, pp. 1364-1371
-
-
Clark, R.B.1
Bishop-Bailey, D.2
Estrada-Hernandez, T.3
Hla, T.4
Puddington, L.5
Padula, S.J.6
-
3
-
-
0034672472
-
Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-12 production in murine dendritic cells
-
Faveeuw C, Fougeray S, Angeli V etal. Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-12 production in murine dendritic cells. FEBS Lett 2000; 486:261-266.
-
(2000)
FEBS Lett
, vol.486
, pp. 261-266
-
-
Faveeuw, C.1
Fougeray, S.2
Angeli, V.3
-
4
-
-
0035062387
-
The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis
-
Harris SG, Phipps RP. The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis. Eur J Immunol 2001; 31:1098-1105.
-
(2001)
Eur J Immunol
, vol.31
, pp. 1098-1105
-
-
Harris, S.G.1
Phipps, R.P.2
-
5
-
-
69449086033
-
PPAR gamma regulates retinoic acid-mediated DC induction of Tregs
-
Housley WJ, O'Conor CA, Nichols F etal. PPAR gamma regulates retinoic acid-mediated DC induction of Tregs. J Leukoc Biol 2009; 86:293-301.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 293-301
-
-
Housley, W.J.1
O'Conor, C.A.2
Nichols, F.3
-
6
-
-
0142210174
-
Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor
-
Chung SW, Kang BY, Kim TS. Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor. Mol Pharmacol 2003; 64:1169-1179.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 1169-1179
-
-
Chung, S.W.1
Kang, B.Y.2
Kim, T.S.3
-
7
-
-
0001297403
-
Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT
-
Yang XY, Wang LH, Chen T etal. Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT. J Biol Chem 2000; 275:4541-4544.
-
(2000)
J Biol Chem
, vol.275
, pp. 4541-4544
-
-
Yang, X.Y.1
Wang, L.H.2
Chen, T.3
-
8
-
-
78650642538
-
Peroxisome proliferator-activated receptor α and γ agonists together with TGFβ convert human CD4+CD25- T cells into functional Foxp3+ regulatory T cells
-
Lei J, Hasegawa H, Matsumoto T, Yasukawa M. Peroxisome proliferator-activated receptor α and γ agonists together with TGFβ convert human CD4+CD25- T cells into functional Foxp3+ regulatory T cells. J Immunol 2010; 185:7186-7198.
-
(2010)
J Immunol
, vol.185
, pp. 7186-7198
-
-
Lei, J.1
Hasegawa, H.2
Matsumoto, T.3
Yasukawa, M.4
-
9
-
-
33947615887
-
Peroxisome proliferator-activated receptor gamma (PPARgamma) and immunoregulation: enhancement of regulatory T cells through PPARgamma-dependent and independent mechanisms
-
Wohlfert EA, Nichols FC, Nevius E, Clark RB. Peroxisome proliferator-activated receptor gamma (PPARgamma) and immunoregulation: enhancement of regulatory T cells through PPARgamma-dependent and independent mechanisms. J Immunol 2007; 178:4129-4135.
-
(2007)
J Immunol
, vol.178
, pp. 4129-4135
-
-
Wohlfert, E.A.1
Nichols, F.C.2
Nevius, E.3
Clark, R.B.4
-
10
-
-
33847403883
-
Peroxisome proliferator activated receptor gamma is required for regulatory CD4+ T cell-mediated protection against colitis
-
Hontecillas R, Bassaganya-Riera J. Peroxisome proliferator activated receptor gamma is required for regulatory CD4+ T cell-mediated protection against colitis. J Immunol 2007; 178:2940-2949.
-
(2007)
J Immunol
, vol.178
, pp. 2940-2949
-
-
Hontecillas, R.1
Bassaganya-Riera, J.2
-
11
-
-
84862986986
-
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
-
Cipolletta D, Feuerer M, Am L etal. PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature 2012; 486:549-553.
-
(2012)
Nature
, vol.486
, pp. 549-553
-
-
Cipolletta, D.1
Feuerer, M.2
Am, L.3
-
12
-
-
4444280899
-
Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease
-
Bassaganya-Riera J, Reynolds K, Martino-Catt S etal. Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease. Gasteroenterology 2004; 127:777-791.
-
(2004)
Gasteroenterology
, vol.127
, pp. 777-791
-
-
Bassaganya-Riera, J.1
Reynolds, K.2
Martino-Catt, S.3
-
13
-
-
0032544790
-
Troglitazone prevents insulin dependent diabetes in the non-obese diabetic mouse
-
Beales PE, Liddi R, Giorgini AE etal. Troglitazone prevents insulin dependent diabetes in the non-obese diabetic mouse. Eur J Pharmacol 1998; 357:221-225.
-
(1998)
Eur J Pharmacol
, vol.357
, pp. 221-225
-
-
Beales, P.E.1
Liddi, R.2
Giorgini, A.E.3
-
14
-
-
0036499074
-
2 ameliorates experimental autoimmune encephalomyelitis
-
2 ameliorates experimental autoimmune encephalomyelitis. J Immunol 2002; 168:2508-2515.
-
(2002)
J Immunol
, vol.168
, pp. 2508-2515
-
-
Diab, A.1
Deng, C.2
Smith, J.D.3
-
15
-
-
0036260784
-
Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis
-
Feinstein DL, Galea E, Gavrilyuk V etal. Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis. Ann Neurol 2002; 51:694-702.
-
(2002)
Ann Neurol
, vol.51
, pp. 694-702
-
-
Feinstein, D.L.1
Galea, E.2
Gavrilyuk, V.3
-
16
-
-
0141540467
-
Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma
-
Mueller C, Weaver V, Vanden Heuvel JP, August A, Cantorna MT. Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma. Arch Biochem Biophys 2003; 418:186-196.
-
(2003)
Arch Biochem Biophys
, vol.418
, pp. 186-196
-
-
Mueller, C.1
Weaver, V.2
Vanden Heuvel, J.P.3
August, A.4
Cantorna, M.T.5
-
17
-
-
0042624848
-
Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation
-
Woerly G, Honda K, Loyens M etal. Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation. J Exp Med 2003; 198:411-421.
-
(2003)
J Exp Med
, vol.198
, pp. 411-421
-
-
Woerly, G.1
Honda, K.2
Loyens, M.3
-
18
-
-
0035341427
-
Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor γ
-
Nino M, Iwabuchi K, Kikuchi S etal. Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor γ. J Neuroimmunol 2001; 116:40-48.
-
(2001)
J Neuroimmunol
, vol.116
, pp. 40-48
-
-
Nino, M.1
Iwabuchi, K.2
Kikuchi, S.3
-
19
-
-
0036546185
-
Peroxisome proliferator-activated receptor-γ agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation
-
Natarajan C, Bright JJ. Peroxisome proliferator-activated receptor-γ agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. Genes Immun 2002; 3:59-70.
-
(2002)
Genes Immun
, vol.3
, pp. 59-70
-
-
Natarajan, C.1
Bright, J.J.2
-
20
-
-
33747777758
-
PPARgamma as a new therapeutic target in inflammatory bowel diseases
-
Dubuquoy L, Rousseaux C, Thuru X etal. PPARgamma as a new therapeutic target in inflammatory bowel diseases. Gut 2006; 55:1341-1349.
-
(2006)
Gut
, vol.55
, pp. 1341-1349
-
-
Dubuquoy, L.1
Rousseaux, C.2
Thuru, X.3
-
21
-
-
1542498518
-
Peroxisome proliferator-activated receptor-gamma: therapeutic target for diseases beyond diabetes: quo vadis?
-
Pershadsingh HA. Peroxisome proliferator-activated receptor-gamma: therapeutic target for diseases beyond diabetes: quo vadis? Exp Opin Investig Drugs 2004; 13:215-228.
-
(2004)
Exp Opin Investig Drugs
, vol.13
, pp. 215-228
-
-
Pershadsingh, H.A.1
-
22
-
-
47349092662
-
PPAR-gamma: therapeutic potential for multiple sclerosis
-
Drew PD, Xu J, Racke MK. PPAR-gamma: therapeutic potential for multiple sclerosis. PPAR Res 2008; 2008:627463-627472.
-
(2008)
PPAR Res
, vol.2008
, pp. 627463-627472
-
-
Drew, P.D.1
Xu, J.2
Racke, M.K.3
-
23
-
-
1542313910
-
Anti-inflammatory and anti-proliferative actions of PPAR-gamma agonists on T lymphocyte derived from MS patients
-
Schmidt S, Moric E, Schmidt M, Sastre M, Feinstein DL, Heneka MT. Anti-inflammatory and anti-proliferative actions of PPAR-gamma agonists on T lymphocyte derived from MS patients. J Leukoc Biol 2004; 75:478-485.
-
(2004)
J Leukoc Biol
, vol.75
, pp. 478-485
-
-
Schmidt, S.1
Moric, E.2
Schmidt, M.3
Sastre, M.4
Feinstein, D.L.5
Heneka, M.T.6
-
24
-
-
70449394029
-
Pancreatic islet inflammation in type 2 diabetes: from α and β cell compensation to dysfunction
-
Ehses JA, Ellingsgaard H, Boni-Schnetzler M, Donath MY. Pancreatic islet inflammation in type 2 diabetes: from α and β cell compensation to dysfunction. Arch Physiol Biochem 2009; 115:240-247.
-
(2009)
Arch Physiol Biochem
, vol.115
, pp. 240-247
-
-
Ehses, J.A.1
Ellingsgaard, H.2
Boni-Schnetzler, M.3
Donath, M.Y.4
-
25
-
-
41149115561
-
Islet inflammation in type 2 diabetes
-
Donath MY, Schumann DM, Faulenbach M, Ellingsgaard H, Perren A, Ehses JA. Islet inflammation in type 2 diabetes. Diabetes Care 2008; 31:S161-164.
-
(2008)
Diabetes Care
, vol.31
-
-
Donath, M.Y.1
Schumann, D.M.2
Faulenbach, M.3
Ellingsgaard, H.4
Perren, A.5
Ehses, J.A.6
-
26
-
-
67650685521
-
Islet-associated macrophages in type 2 diabetes
-
Richardson SJ, Wilcox A, Bone AJ, Foulis AK, Morgan NG. Islet-associated macrophages in type 2 diabetes. Diabetologia 2009; 52:1686-1688.
-
(2009)
Diabetologia
, vol.52
, pp. 1686-1688
-
-
Richardson, S.J.1
Wilcox, A.2
Bone, A.J.3
Foulis, A.K.4
Morgan, N.G.5
-
27
-
-
82655171679
-
Immunology in the clinic review series; focus on metabolic diseases: development of islet autoimmune disease in type 2 diabetes patients: potential sequelae of chronic inflammation
-
Brooks-Worrell B, Palmer JP. Immunology in the clinic review series; focus on metabolic diseases: development of islet autoimmune disease in type 2 diabetes patients: potential sequelae of chronic inflammation. Clin Exp Immunol 2012; 167:40-46.
-
(2012)
Clin Exp Immunol
, vol.167
, pp. 40-46
-
-
Brooks-Worrell, B.1
Palmer, J.P.2
-
28
-
-
84867911343
-
Biomarkers and immune-modulating therapies for Type 2 diabetes
-
Brooks-Worrell B, Narla R, Palmer JP. Biomarkers and immune-modulating therapies for Type 2 diabetes. Trends Immunol 2012; 33:546-553.
-
(2012)
Trends Immunol
, vol.33
, pp. 546-553
-
-
Brooks-Worrell, B.1
Narla, R.2
Palmer, J.P.3
-
29
-
-
0032940245
-
Cellular immune response to human islet proteins in antibody-positive type 2 diabetic patients
-
Brooks-Worrell B, Juneja R, Minokadeh A, Greenbaum CJ, Palmer JP. Cellular immune response to human islet proteins in antibody-positive type 2 diabetic patients. Diabetes 1999; 48:983-988.
-
(1999)
Diabetes
, vol.48
, pp. 983-988
-
-
Brooks-Worrell, B.1
Juneja, R.2
Minokadeh, A.3
Greenbaum, C.J.4
Palmer, J.P.5
-
30
-
-
34547403175
-
Contrasting cellular and humoral autoimmunity associated with latent autoimmune diabetes in adults
-
Mayer A, Fabien N, Gutowski MC etal. Contrasting cellular and humoral autoimmunity associated with latent autoimmune diabetes in adults. Eur J Endocrin 2007; 157:53-61.
-
(2007)
Eur J Endocrin
, vol.157
, pp. 53-61
-
-
Mayer, A.1
Fabien, N.2
Gutowski, M.C.3
-
31
-
-
79951689303
-
Identification of autoantibody negative autoimmune type 2 diabetes patients
-
Brooks-Worrell B, Reichow JL, Goel A, Ismail H, Palmer JP. Identification of autoantibody negative autoimmune type 2 diabetes patients. Diabetes Care 2011; 34:168-173.
-
(2011)
Diabetes Care
, vol.34
, pp. 168-173
-
-
Brooks-Worrell, B.1
Reichow, J.L.2
Goel, A.3
Ismail, H.4
Palmer, J.P.5
-
32
-
-
34547605312
-
T cell responses to islet antigens improves detection of autoimmune diabetes and identifies patients with more severe β-cell lesions in phenotypic type 2 diabetes
-
Goel A, Chiu H, Felton J, Palmer JP, Brooks-Worrell B. T cell responses to islet antigens improves detection of autoimmune diabetes and identifies patients with more severe β-cell lesions in phenotypic type 2 diabetes. Diabetes 2007; 56:2110-2115.
-
(2007)
Diabetes
, vol.56
, pp. 2110-2115
-
-
Goel, A.1
Chiu, H.2
Felton, J.3
Palmer, J.P.4
Brooks-Worrell, B.5
-
33
-
-
55449125262
-
Rosiglitazone and pioglitazone similarly improve insulin sensitivity and secretion, glucose tolerance and adipocytokines in type 2 diabetic patients
-
Miyaaki Y, DeFronzo RA. Rosiglitazone and pioglitazone similarly improve insulin sensitivity and secretion, glucose tolerance and adipocytokines in type 2 diabetic patients. Diabetes Obes Metab 2008; 10:1204-1211.
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 1204-1211
-
-
Miyaaki, Y.1
DeFronzo, R.A.2
-
34
-
-
33845405222
-
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
-
Kahn SE, Haffner SM, Heise MA etal. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006; 355:2427-2443.
-
(2006)
N Engl J Med
, vol.355
, pp. 2427-2443
-
-
Kahn, S.E.1
Haffner, S.M.2
Heise, M.A.3
-
35
-
-
0030589224
-
Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins
-
Brooks-Worrell B, Starkebaum GA, Greenbaum C, Palmer JP. Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins. J Immunol 1996; 157:5668-5674.
-
(1996)
J Immunol
, vol.157
, pp. 5668-5674
-
-
Brooks-Worrell, B.1
Starkebaum, G.A.2
Greenbaum, C.3
Palmer, J.P.4
-
36
-
-
0035871763
-
Intermolecular antigen spreading occurs during the pre-clinical period of human type 1 diabetes
-
Brooks-Worrell B, Gersuk VH, Greenbaum C, Palmer JP. Intermolecular antigen spreading occurs during the pre-clinical period of human type 1 diabetes. J Immunol 2001; 166:5265-5270.
-
(2001)
J Immunol
, vol.166
, pp. 5265-5270
-
-
Brooks-Worrell, B.1
Gersuk, V.H.2
Greenbaum, C.3
Palmer, J.P.4
-
37
-
-
33750594322
-
Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled study
-
Seyfert-Margolis V, Gisler TD, Asare AL etal. Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled study. Diabetes 2006; 55:2588-2594.
-
(2006)
Diabetes
, vol.55
, pp. 2588-2594
-
-
Seyfert-Margolis, V.1
Gisler, T.D.2
Asare, A.L.3
-
38
-
-
70350534475
-
Validity and reproducibility of measurement of islet autoreactivity by T cell assays in subjects with early type 1 diabetes
-
Herold KC, Brooks-Worrell B, Palmer J etal. Validity and reproducibility of measurement of islet autoreactivity by T cell assays in subjects with early type 1 diabetes. Diabetes Care 2009; 58:2588-2595.
-
(2009)
Diabetes Care
, vol.58
, pp. 2588-2595
-
-
Herold, K.C.1
Brooks-Worrell, B.2
Palmer, J.3
-
39
-
-
65049083839
-
Improved T cell assay for identification of Type 1 diabetes patients
-
Brooks-Worrell B, Warsen A, Palmer JP. Improved T cell assay for identification of Type 1 diabetes patients. J Immunol Methods 2009; 344:79-83.
-
(2009)
J Immunol Methods
, vol.344
, pp. 79-83
-
-
Brooks-Worrell, B.1
Warsen, A.2
Palmer, J.P.3
-
40
-
-
33846468972
-
Peroxisome proliferator-activated receptor-g agonists suppress the production of IL-12 family cytokines by activated glia
-
Xu J, Drew PD. Peroxisome proliferator-activated receptor-g agonists suppress the production of IL-12 family cytokines by activated glia. J Immunol 2007; 178:1904-1913.
-
(2007)
J Immunol
, vol.178
, pp. 1904-1913
-
-
Xu, J.1
Drew, P.D.2
-
41
-
-
0027336689
-
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
-
Hsieh CS, Macatonia SE, Tripp CS, Wolf SF, O'Garra A, Murphy KM. Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science 1993; 260:547-549.
-
(1993)
Science
, vol.260
, pp. 547-549
-
-
Hsieh, C.S.1
Macatonia, S.E.2
Tripp, C.S.3
Wolf, S.F.4
O'Garra, A.5
Murphy, K.M.6
-
42
-
-
0027409793
-
Natural killer cell stimulatory factor (interleukin-12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells
-
Manetti R, Parronchi P, Giudizi MG etal. Natural killer cell stimulatory factor (interleukin-12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells. J Exp Med 1993; 177:1199-1204.
-
(1993)
J Exp Med
, vol.177
, pp. 1199-1204
-
-
Manetti, R.1
Parronchi, P.2
Giudizi, M.G.3
-
43
-
-
0028809507
-
Expression of co-stimulatory molecules B7-1 (CD80), B-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
-
Windhagen A, Newcombe J, Dangond F etal. Expression of co-stimulatory molecules B7-1 (CD80), B-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J Exp Med 1995; 182:1985-1996.
-
(1995)
J Exp Med
, vol.182
, pp. 1985-1996
-
-
Windhagen, A.1
Newcombe, J.2
Dangond, F.3
-
44
-
-
0032528896
-
Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy
-
Comabella M, Balashov K, Issaadeh S, Smith D, Weiner HL, Khoury SJ. Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy. J Clin Invest 1998; 102:671-678.
-
(1998)
J Clin Invest
, vol.102
, pp. 671-678
-
-
Comabella, M.1
Balashov, K.2
Issaadeh, S.3
Smith, D.4
Weiner, H.L.5
Khoury, S.J.6
-
45
-
-
0004882072
-
Elevated serum levels of interleukin-12 in chronic progressive multiple sclerosis
-
Nicoletti F, Patti F, Cocuzza C etal. Elevated serum levels of interleukin-12 in chronic progressive multiple sclerosis. J Neuroimmunol 1996; 70:87-90.
-
(1996)
J Neuroimmunol
, vol.70
, pp. 87-90
-
-
Nicoletti, F.1
Patti, F.2
Cocuzza, C.3
|