Gene delivery using ternary lipopolyplexes incorporating branched cationic peptides: The role of peptide sequence and branching

Molecular Pharmaceutics

Volumn 10, Issue 1, 2013, Pages 127-141

  Welser, Katharina ^a   Campbell, Frederick ^a   Kudsiova, Laila ^b   Mohammadi, Atefeh ^a   Dawson, Natalie ^a   Hart, Stephen L ^c   Barlow, David J ^b   Hailes, Helen C ^a   Lawrence, M Jayne ^b   Tabor, Alethea B ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Molecular Microbiology Research Laboratory   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

branched peptides; cationic peptides; circular dichroism; lipids; nonviral gene delivery; small angle neutron scattering; structure activity correlation

Indexed keywords

1,2 DI O OCTADECENYL 3 TRIMETHYLAMMONIUM PROPANE; ARGININE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; LIPID; LYSINE; PLASMID DNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BRANCHING MORPHOGENESIS; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIGHT SCATTERING; LUNG ALVEOLUS CELL; NEUTRON SCATTERING; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SURFACE CHARGE; ZETA POTENTIAL;

CATIONS; CELL LINE, TUMOR; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; CIRCULAR DICHROISM; DNA; EPITHELIAL CELLS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; LIPIDS; PARTICLE SIZE; PEPTIDES; PLASMIDS; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; TRANSFECTION;

EID: 84872166236     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300187t     Document Type: Article

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