Stability of peptide-condensed plasmid DNA formulations

Journal of Pharmaceutical Sciences

Volumn 87, Issue 6, 1998, Pages 678-683

  Adami, Roger C ^a   Collard, Wendy T ^a   Gupta, Shamita A ^a   Kwok, Kai Y ^a   Bonadio, Jeffrey ^a   Rice, Kevin G ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; LYSINE; POLYPEPTIDE; PROTECTIVE AGENT;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; DNA STRUCTURE; DNA SYNTHESIS; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; MOLECULAR WEIGHT; PLASMID; POLYMERIZATION;

EID: 0031834992     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js9800477     Document Type: Article

References (22)

1. Kawabata, K.; Takakura, Y.; Hashida, M. The Fate of Plasmid DNA After Intravenous Injection in Mice: Involvement of Scavenger Receptors in Its Hepatic Uptake Pharm. Res. 1995, 12, 825-30.
2. Niidome, T.; Ohmori, N.; Ichinose, A.; Wada, A.; Mihara, H.; Hirayama, T.; Aoyagi, H. Binding of Cationic α-Helical Peptides to Plasmid DNA and Their Gene Transfer Abilities into Cells. J. Biol. Chem. 1997, 24, 15307-15312.
3. Wadhwa, M. S.; Knoell, D.; Young, T.; Rice, K. G. Targeted Gene Delivery with a Low Molecular Weight Glycopeptide Carrier. Bioconjugate Chem. 1995, 6, 283-291.
4. Ferkol, H.; Perales, J. C.; Mularo, F.; Hanson, R. W. Receptor Mediated Gene Transfer into Macrophages. Proc. Natl. Acad. Sci. 1996, 93, 101-105.
5. Midoux, P.; Mendes, C.; Legrand, A.; Raimond, J.; Mayer, R.; Monsigny, M.; Roch, A. C. Specific Gene Transfer Mediated by Lactosylated Poly-L-Lysine into Hepatoma Cells. Nucleic Acid Res. 1993, 21, 871-878.
6. Zhang, Y. P.; Reimer, D. L.; Zhang, G.; Lee, P. H.; Bally, M. B. Self-Assembling DNA-Lipid Particles for Gene Transfer. Pharm. Res. 1997, 14, 190-196.
7. 33P] DNA Following Intravenous Administration of DNA/ Cationic Lipid Complexes in Mice: Use of a Novel Radionuclide Approach. J. Pharm. Sci. 1996, 85, 612-618.
8. Eastman, S. J.; Tousignant, J. D.; Lukason, M. J.; Murray, H.; Siegel, C. S.; Constantino, P.; Harris, D. J.; Cheng, S. H.; Scheule, R. K. Optimization of Formulations and Conditions for the Aerosol Delivery of Functional Cationic Lipid: DNA Complexes. Hum. Gene Ther. 1997, 8, 313-322.
9. Lee, R. J.; Huang, L. Folate-Targeted, Anionic Liposome-Entrapped Polylysine-Condensed DNA for Tumor Cell-Specific Gene Transfer. J. Biol. Chem. 1996, 271, 8481-8487.
10. Gao, X.; Huang, L. Potentiation of Cationic Liposome-Mediated Gene Delivery by Polycations. Biochemistry 1996, 35, 1027-1036.
11. Cheng, P. W. Receptor Ligand-Facilitated Gene Transfer: Enhancement of Liposome-Mediated Gene Transfer and Expression by Transferrin. Hum. Gene Ther. 1996, 7, 275-282.
12. Niemiec, S. M.; Latta, J. M.; Ramachandran C.; Weiner, N. D. Perifollicular Transgenic Expression of Human Interleukin-1 Receptor Antagonist Protein Following Topical Application of Novel Liposome-Plasmid DNA Formulations In Vivo. J. Pharm. Sci. 1997, 86, 701-708.
13. Mathiowitz, E.; Jacob, J. S.; Jong, Y. S.; Carino, G. P.; Chickering, D. E.; Chaturvedi, P.; Santos, C. A.; Vijayaraghavan, K.; Montgomery, S.; Bassett, M.; Morrell, C. Biologically Erodable Microspheres as Potential Oral Drug Delivery Systems. Nature 1997, 386, 410-414.
14. Wyber, K. A.; Andrews, J.; D'Emanuele, A. The Use of Sonication for the Efficient Delivery of Plasmid DNA into Cells. Pharm. Res. 1997, 14, 750-756.
15. Leibiger, I.; Leibiger, B.; Sarrach, D.; Walther, R.; Zuhlke, H. Genetic Manipulation of Rat Hepatocytes In Vivo. Implications for a Therapy Model of Type-1 Diabetes. Biomed. Biochim. Acta 1990, 12, 1193-1200.
16. Wasan, E. K.; Reimer, D. L.; Bally M. B. Plasmid DNA is Protected Against Ultrasonic Cavitation-Induced Damage When Complexed to Cationic Liposomes. J. Pharm. Sci. 1996, 85, 427-433.
17. Lew, D.; Parker, S. E.; Latimer, T.; Abai, A. M.; Kuwahara-Rundell, A.; Doh, S. G.; Yang, Z. Y.; Laface, D.; Gromkowski, S. H.; Nabel, G. J.; Manthorpe, M.; Norman, J. Cancer Gene Therapy Using Plasmid DNA: Pharmacokinetic Study of DNA Following Injection in Mice. Hum. Gene Ther., 1995, 6, 553-564.
18. Puyal, C.; Milhaud, P.; Bienvenue, A.; Philippot, J. R. A New Cationic Liposome Encapsulating Genetic Material. A Potential Delivery System for Polynucleotides. Eur. J. Biochem. 1995, 228, 697-703.
19. Wadhwa, M. S.; Collard, W. T.; Adami, R. C.; Mckenzie, D. L..; Rice, K. G. Peptide-Mediated Gene Delivery: Influence of Peptide Structure on Gene Expression. Bioconjugate Chem. 1997, 8, 81-88.
20. Kunitz, M. Crystalline Desoxyribonuclease I. Isolation and General Properties Spectrophotometric Method for the Measurement of Desoxyribonuclease Activity. J. Gen. Physiol. 1950, 33, 349-362.
21. Elsner, H. I.; Lindblad, E. B. Ultrasonic Degradation of DNA. DNA 1989, 8, 697-701.
22. Wolfert, M. A.; Seymour, L. W. Atomic Force Microscopic Analysis of the Influence of the Molecular Weight of Poly-(L)lysine on the size of Polylelectrolyte Complexes Formed with DNA. Gene Ther. 1996, 3, 269-273.