-
1
-
-
0141682318
-
Primordial germ cells in the mouse
-
McLaren, A. (2003) Primordial germ cells in the mouse. Dev. Biol., 262, 1-15.
-
(2003)
Dev. Biol.
, vol.262
, pp. 1-15
-
-
Mclaren, A.1
-
2
-
-
0019393572
-
Proliferation and migration of primordial germ cells during compensatory growth in mouse embryos
-
Tam, P.P. and Snow, M.H. (1981) Proliferation and migration of primordial germ cells during compensatory growth in mouse embryos. J. Embryol. Exp. Morphol., 64, 133-147.
-
(1981)
J. Embryol. Exp. Morphol.
, vol.64
, pp. 133-147
-
-
Tam, P.P.1
Snow, M.H.2
-
3
-
-
0026669014
-
Long-term proliferation of mouse primordial germ cells in culture
-
Resnick, J.L., Bixler, L.S., Cheng, L. and Donovan, P.J. (1992) Long-term proliferation of mouse primordial germ cells in culture. Nature, 359, 550-551.
-
(1992)
Nature
, vol.359
, pp. 550-551
-
-
Resnick, J.L.1
Bixler, L.S.2
Cheng, L.3
Donovan, P.J.4
-
4
-
-
0026699762
-
Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture
-
Matsui, Y., Zsebo, K. and Hogan, B.L. (1992) Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell, 70, 841-847.
-
(1992)
Cell
, vol.70
, pp. 841-847
-
-
Matsui, Y.1
Zsebo, K.2
Hogan, B.L.3
-
5
-
-
0027714752
-
Proliferation and migration of primordial germ cells in We/We mouse embryos
-
Buehr, M., McLaren, A., Bartley, A. and Darling, S. (1993) Proliferation and migration of primordial germ cells in We/We mouse embryos. Dev. Dyn., 198, 182-189.
-
(1993)
Dev. Dyn.
, vol.198
, pp. 182-189
-
-
Buehr, M.1
Mclaren, A.2
Bartley, A.3
Darling, S.4
-
6
-
-
0001047032
-
Gene-induced embryological modifications of primordial germ cells in the mouse
-
Mintz, B. and Russell, E.S. (1957) Gene-induced embryological modifications of primordial germ cells in the mouse. J. Exp. Zool. Part A Ecol. Genet. Physiol., 134, 207-237.
-
(1957)
J. Exp. Zool. Part A Ecol. Genet. Physiol.
, vol.134
, pp. 207-237
-
-
Mintz, B.1
Russell, E.S.2
-
7
-
-
33846146040
-
Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration
-
Runyan, C., Schaible, K., Molyneaux, K., Wang, Z., Levin, L. and Wylie, C. (2006) Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration. Development, 133, 4861-4869.
-
(2006)
Development
, vol.133
, pp. 4861-4869
-
-
Runyan, C.1
Schaible, K.2
Molyneaux, K.3
Wang, Z.4
Levin, L.5
Wylie, C.6
-
8
-
-
0025741284
-
Requirement for mast cell growth factor for primordial germ cell survival in culture
-
Dolci, S., Williams, D.E., Ernst, M.K., Resnick, J.L., Brannan, C.I., Lock, L.F., Lyman, S.D., Boswell, H.S. and Donovan, P.J. (1991) Requirement for mast cell growth factor for primordial germ cell survival in culture. Nature, 352, 809-811.
-
(1991)
Nature
, vol.352
, pp. 809-811
-
-
Dolci, S.1
Williams, D.E.2
Ernst, M.K.3
Resnick, J.L.4
Brannan, C.I.5
Lock, L.F.6
Lyman, S.D.7
Boswell, H.S.8
Donovan, P.J.9
-
9
-
-
0025779118
-
Effects of the steel gene product on mouse primordial germ cells in culture
-
Godin, I., Deed, R., Cooke, J., Zsebo, K., Dexter, M. and Wylie, C.C. (1991) Effects of the steel gene product on mouse primordial germ cells in culture. Nature, 352, 807-809.
-
(1991)
Nature
, vol.352
, pp. 807-809
-
-
Godin, I.1
Deed, R.2
Cooke, J.3
Zsebo, K.4
Dexter, M.5
Wylie, C.C.6
-
10
-
-
0025939841
-
Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture
-
Matsui, Y., Toksoz, D., Nishikawa, S., Williams, D., Zsebo, K. and Hogan, B.L. (1991) Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture. Nature, 353, 750-752.
-
(1991)
Nature
, vol.353
, pp. 750-752
-
-
Matsui, Y.1
Toksoz, D.2
Nishikawa, S.3
Williams, D.4
Zsebo, K.5
Hogan, B.L.6
-
11
-
-
34249883075
-
Chemoattractant action and molecular signaling pathways of Kit ligand on mouse primordial germ cells
-
Farini, D., La Sala, G., Tedesco, M. and De Felici, M. (2007) Chemoattractant action and molecular signaling pathways of Kit ligand on mouse primordial germ cells. Dev. Biol., 306, 572-583.
-
(2007)
Dev. Biol.
, vol.306
, pp. 572-583
-
-
Farini, D.1
Sala, G.L.2
Tedesco, M.3
Felici, M.D.4
-
12
-
-
84855290502
-
Ror2 enhances polarity and directional migration of primordial germ cells
-
Laird, D.J., Altshuler-Keylin, S., Kissner, M.D., Zhou, X. and Anderson, K.V. (2011) Ror2 enhances polarity and directional migration of primordial germ cells. PLoS Genet., 7, e1002428.
-
(2011)
PLoS Genet.
, vol.7
-
-
Laird, D.J.1
Altshuler-Keylin, S.2
Kissner, M.D.3
Zhou, X.4
Anderson, K.V.5
-
13
-
-
0028959163
-
Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines
-
Kitayama, H., Kanakura, Y., Furitsu, T., Tsujimura, T., Oritani, K., Ikeda, H., Sugahara, H., Mitsui, H., Kanayama, Y., Kitamura, Y. et al. (1995) Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines. Blood, 85, 790-798.
-
(1995)
Blood
, vol.85
, pp. 790-798
-
-
Kitayama, H.1
Kanakura, Y.2
Furitsu, T.3
Tsujimura, T.4
Oritani, K.5
Ikeda, H.6
Sugahara, H.7
Mitsui, H.8
Kanayama, Y.9
Kitamura, Y.10
-
14
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
Hirota, S., Isozaki, K., Moriyama, Y., Hashimoto, K., Nishida, T., Ishiguro, S., Kawano, K., Hanada, M., Kurata, A., Takeda, M. et al. (1998) Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science, 279, 577-580.
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
Hashimoto, K.4
Nishida, T.5
Ishiguro, S.6
Kawano, K.7
Hanada, M.8
Kurata, A.9
Takeda, M.10
-
15
-
-
48549093520
-
Loss of the transmembrane but not the soluble kit ligand isoform increases testicular germ cell tumor susceptibility in mice
-
Heaney, J.D., Lam, M.Y., Michelson, M.V. and Nadeau, J.H. (2008) Loss of the transmembrane but not the soluble kit ligand isoform increases testicular germ cell tumor susceptibility in mice. Cancer Res., 68, 5193-5197.
-
(2008)
Cancer Res.
, vol.68
, pp. 5193-5197
-
-
Heaney, J.D.1
Lam, M.Y.2
Michelson, M.V.3
Nadeau, J.H.4
-
16
-
-
36849048758
-
Mutations of c-kit gene in bilateral testicular germ cell tumours in Japan
-
Sakuma, Y., Matsukuma, S., Yoshihara, M., Sakurai, S., Nishii, M., Kishida, T., Kubota, Y., Nagashima, Y., Inayama, Y., Sasaki, T. et al. (2008) Mutations of c-kit gene in bilateral testicular germ cell tumours in Japan. Cancer Lett., 259, 119-126.
-
(2008)
Cancer Lett.
, vol.259
, pp. 119-126
-
-
Sakuma, Y.1
Matsukuma, S.2
Yoshihara, M.3
Sakurai, S.4
Nishii, M.5
Kishida, T.6
Kubota, Y.7
Nagashima, Y.8
Inayama, Y.9
Sasaki, T.10
-
17
-
-
10744221713
-
Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors
-
Looijenga, L.H., de Leeuw, H., van Oorschot, M., van Gurp, R.J., Stoop, H., Gillis, A.J., de Gouveia Brazao, C.A., Weber, R.F., Kirkels, W.J., van Dijk, T. et al. (2003) Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors. Cancer Res., 63, 7674-7678.
-
(2003)
Cancer Res.
, vol.63
, pp. 7674-7678
-
-
Looijenga, L.H.1
Leeuw, H.D.2
Oorschot, M.V.3
Gurp, R.J.V.4
Stoop, H.5
Gillis, A.J.6
Brazao, C.A.D.G.7
Weber, R.F.8
Kirkels, W.J.9
Dijk, T.V.10
-
18
-
-
0038312141
-
Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase
-
Sommer, G., Agosti, V., Ehlers, I., Rossi, F., Corbacioglu, S., Farkas, J., Moore, M., Manova, K., Antonescu, C.R. and Besmer, P. (2003) Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase. Proc. Natl Acad. Sci. USA, 100, 6706-6711.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 6706-6711
-
-
Sommer, G.1
Agosti, V.2
Ehlers, I.3
Rossi, F.4
Corbacioglu, S.5
Farkas, J.6
Moore, M.7
Manova, K.8
Antonescu, C.R.9
Besmer, P.10
-
19
-
-
0031848146
-
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene
-
Nishida, T., Hirota, S., Taniguchi, M., Hashimoto, K., Isozaki, K., Nakamura, H., Kanakura, Y., Tanaka, T., Takabayashi, A., Matsuda, H. et al. (1998) Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat. Genet., 19, 323-324.
-
(1998)
Nat. Genet.
, vol.19
, pp. 323-324
-
-
Nishida, T.1
Hirota, S.2
Taniguchi, M.3
Hashimoto, K.4
Isozaki, K.5
Nakamura, H.6
Kanakura, Y.7
Tanaka, T.8
Takabayashi, A.9
Matsuda, H.10
-
20
-
-
25844507795
-
Signaling by Kit protein-tyrosine kinase-the stem cell factor receptor
-
Roskoski, R. Jr (2005) Signaling by Kit protein-tyrosine kinase-the stem cell factor receptor. Biochem. Biophys. Res. Commun., 337, 1-13.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.337
, pp. 1-13
-
-
Roskoski, R.Jr.1
-
21
-
-
0026611951
-
p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein
-
Duronio, V., Welham, M.J., Abraham, S., Dryden, P. and Schrader, J.W. (1992) p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein. Proc. Natl Acad. Sci. USA, 89, 1587-1591.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 1587-1591
-
-
Duronio, V.1
Welham, M.J.2
Abraham, S.3
Dryden, P.4
Schrader, J.W.5
-
22
-
-
0028128692
-
Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells
-
Serve, H., Hsu, Y.C. and Besmer, P. (1994) Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells. J. Biol. Chem., 269, 6026-6030.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6026-6030
-
-
Serve, H.1
Hsu, Y.C.2
Besmer, P.3
-
23
-
-
0031472434
-
Stem cell factor, the JAK-STAT pathway and signal transduction
-
Linnekin, D., Mou, S., Deberry, C.S., Weiler, S.R., Keller, J.R., Ruscetti, F.W. and Longo, D.L. (1997) Stem cell factor, the JAK-STAT pathway and signal transduction. Leuk. Lymphoma, 27, 439-444.
-
(1997)
Leuk. Lymphoma
, vol.27
, pp. 439-444
-
-
Linnekin, D.1
Mou, S.2
Deberry, C.S.3
Weiler, S.R.4
Keller, J.R.5
Ruscetti, F.W.6
Longo, D.L.7
-
24
-
-
0030668320
-
Stat1 associates with c-kit and is activated in response to stem cell factor
-
Deberry, C., Mou, S. and Linnekin, D. (1997) Stat1 associates with c-kit and is activated in response to stem cell factor. Biochem. J., 327, 73-80.
-
(1997)
Biochem. J.
, vol.327
, pp. 73-80
-
-
Deberry, C.1
Mou, S.2
Linnekin, D.3
-
25
-
-
0030833445
-
Lyn associates with the juxtamembrane region of c-Kit and is activated by stem cell factor in hematopoietic cell lines and normal progenitor cells
-
Linnekin, D., DeBerry, C.S. and Mou, S. (1997) Lyn associates with the juxtamembrane region of c-Kit and is activated by stem cell factor in hematopoietic cell lines and normal progenitor cells. J. Biol. Chem., 272, 27450-27455.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27450-27455
-
-
Linnekin, D.1
Deberry, C.S.2
Mou, S.3
-
26
-
-
0034654307
-
Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses
-
Kissel, H., Timokhina, I., Hardy, M.P., Rothschild, G., Tajima, Y., Soares, V., Angeles, M., Whitlow, S.R., Manova, K. and Besmer, P. (2000) Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses. EMBO J., 19, 1312-1326.
-
(2000)
EMBO J.
, vol.19
, pp. 1312-1326
-
-
Kissel, H.1
Timokhina, I.2
Hardy, M.P.3
Rothschild, G.4
Tajima, Y.5
Soares, V.6
Angeles, M.7
Whitlow, S.R.8
Manova, K.9
Besmer, P.10
-
27
-
-
0033981729
-
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility
-
Blume-Jensen, P., Jiang, G., Hyman, R., Lee, K.F., O'Gorman, S. and Hunter, T. (2000) Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility. Nat. Genet., 24, 157-162.
-
(2000)
Nat. Genet.
, vol.24
, pp. 157-162
-
-
Blume-Jensen, P.1
Jiang, G.2
Hyman, R.3
Lee, K.F.4
O'gorman, S.5
Hunter, T.6
-
28
-
-
1942533518
-
Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages
-
USA
-
Kimura, Y., Jones, N., Kluppel, M., Hirashima, M., Tachibana, K., Cohn, J.B., Wrana, J.L., Pawson, T. and Bernstein, A. (2004) Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages. Proc. Natl Acad. Sci. USA, 101, 6015-6020.
-
(2004)
Proc. Natl Acad. Sci.
, vol.101
, pp. 6015-6020
-
-
Kimura, Y.1
Jones, N.2
Kluppel, M.3
Hirashima, M.4
Tachibana, K.5
Cohn, J.B.6
Wrana, J.L.7
Pawson, T.8
Bernstein, A.9
-
29
-
-
78650736648
-
Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background
-
Cook, M.S., Munger, S.C., Nadeau, J.H. and Capel, B. (2011) Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development, 138, 23-32.
-
(2011)
Development
, vol.138
, pp. 23-32
-
-
Cook, M.S.1
Munger, S.C.2
Nadeau, J.H.3
Capel, B.4
-
30
-
-
45349107280
-
Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice
-
Kurimoto, K., Yabuta, Y., Ohinata, Y., Shigeta, M., Yamanaka, K. and Saitou, M. (2008) Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice. Genes Dev., 22, 1617-1635.
-
(2008)
Genes Dev.
, vol.22
, pp. 1617-1635
-
-
Kurimoto, K.1
Yabuta, Y.2
Ohinata, Y.3
Shigeta, M.4
Yamanaka, K.5
Saitou, M.6
-
31
-
-
0025611985
-
Gonadal expression of c-kit encoded at the W locus of the mouse
-
Manova, K., Nocka, K., Besmer, P. and Bachvarova, R.F. (1990) Gonadal expression of c-kit encoded at the W locus of the mouse. Development, 110, 1057-1069.
-
(1990)
Development
, vol.110
, pp. 1057-1069
-
-
Manova, K.1
Nocka, K.2
Besmer, P.3
Bachvarova, R.F.4
-
32
-
-
67650714475
-
Steel factor controls primordial germ cell survival and motility from the time of their specification in the allantois, and provides a continuous niche throughout their migration
-
Gu, Y., Runyan, C., Shoemaker, A., Surani, A. and Wylie, C. (2009) Steel factor controls primordial germ cell survival and motility from the time of their specification in the allantois, and provides a continuous niche throughout their migration. Development, 136, 1295-1303.
-
(2009)
Development
, vol.136
, pp. 1295-1303
-
-
Gu, Y.1
Runyan, C.2
Shoemaker, A.3
Surani, A.4
Wylie, C.5
-
33
-
-
20944433211
-
Analysis of mouse embryonic patterning and morphogenesis by forward genetics
-
Garcia-Garcia, M.J., Eggenschwiler, J.T., Caspary, T., Alcorn, H.L., Wyler, M.R., Huangfu, D., Rakeman, A.S., Lee, J.D., Feinberg, E.H., Timmer, J.R. et al. (2005) Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Proc. Natl Acad. Sci. USA, 102, 5913-5919.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 5913-5919
-
-
Garcia-Garcia, M.J.1
Eggenschwiler, J.T.2
Caspary, T.3
Alcorn, H.L.4
Wyler, M.R.5
Huangfu, D.6
Rakeman, A.S.7
Lee, J.D.8
Feinberg, E.H.9
Timmer, J.R.10
-
34
-
-
0025334596
-
Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W
-
Nocka, K., Tan, J.C., Chiu, E., Chu, T.Y., Ray, P., Traktman, P. and Besmer, P. (1990) Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W. EMBO J., 9, 1805-1813.
-
(1990)
EMBO J.
, vol.9
, pp. 1805-1813
-
-
Nocka, K.1
Tan, J.C.2
Chiu, E.3
Chu, T.Y.4
Ray, P.5
Traktman, P.6
Besmer, P.7
-
35
-
-
0016852799
-
A study of the primordial germ cells during their migratory phase in Steel mutant mice
-
McCoshen, J.A. and McCallion, D.J. (1975) A study of the primordial germ cells during their migratory phase in Steel mutant mice. Experientia, 31, 589-590.
-
(1975)
Experientia
, vol.31
, pp. 589-590
-
-
Mccoshen, J.A.1
Mccallion, D.J.2
-
36
-
-
0033387530
-
Germline-specific expression of the Oct-4/green fluorescent protein (GFP) transgene in mice
-
Yoshimizu, T., Sugiyama, N., De Felice, M., Yeom, Y.I., Ohbo, K., Masuko, K., Obinata, M., Abe, K., Scholer, H.R. and Matsui, Y. (1999) Germline-specific expression of the Oct-4/green fluorescent protein (GFP) transgene in mice. Dev. Growth Differ., 41, 675-684.
-
(1999)
Dev. Growth Differ.
, vol.41
, pp. 675-684
-
-
Yoshimizu, T.1
Sugiyama, N.2
De Felice, M.3
Yeom, Y.I.4
Ohbo, K.5
Masuko, K.6
Obinata, M.7
Abe, K.8
Scholer, H.R.9
Matsui, Y.10
-
37
-
-
0028151430
-
Mechanism of down-regulation of c-kit receptor
-
Roles of receptor tyrosine kinase, phosphatidylinositol 3 '-kinase, and protein kinase C
-
Yee, N.S., Hsiau, C.W., Serve, H., Vosseller, K. and Besmer, P. (1994) Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphatidylinositol 3 '-kinase, and protein kinase C. J. Biol. Chem., 269, 31991-31998.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 31991-31998
-
-
Yee, N.S.1
Hsiau, C.W.2
Serve, H.3
Vosseller, K.4
Besmer, P.5
-
38
-
-
33748059560
-
Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor
-
Rossi, F., Ehlers, I., Agosti, V., Socci, N.D., Viale, A., Sommer, G., Yozgat, Y., Manova, K., Antonescu, C.R. and Besmer, P. (2006) Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor. Proc. Natl Acad. Sci. USA, 103, 12843-12848.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 12843-12848
-
-
Rossi, F.1
Ehlers, I.2
Agosti, V.3
Socci, N.D.4
Viale, A.5
Sommer, G.6
Yozgat, Y.7
Manova, K.8
Antonescu, C.R.9
Besmer, P.10
-
39
-
-
31144476177
-
The roles of FGF signaling in germ cell migration in the mouse
-
Takeuchi, Y., Molyneaux, K., Runyan, C., Schaible, K. and Wylie, C. (2005) The roles of FGF signaling in germ cell migration in the mouse. Development, 132, 5399-5409.
-
(2005)
Development
, vol.132
, pp. 5399-5409
-
-
Takeuchi, Y.1
Molyneaux, K.2
Runyan, C.3
Schaible, K.4
Wylie, C.5
-
40
-
-
0032476674
-
Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation
-
Timokhina, I., Kissel, H., Stella, G. and Besmer, P. (1998) Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. EMBO J., 17, 6250-6262.
-
(1998)
EMBO J.
, vol.17
, pp. 6250-6262
-
-
Timokhina, I.1
Kissel, H.2
Stella, G.3
Besmer, P.4
-
41
-
-
77957107846
-
Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib
-
Rossi, F., Yozgat, Y., de Stanchina, E., Veach, D., Clarkson, B., Manova, K., Giancotti, F.G., Antonescu, C.R. and Besmer, P. (2010) Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib. Mol. Cancer Res., 8, 1271-1283.
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 1271-1283
-
-
Rossi, F.1
Yozgat, Y.2
Stanchina, E.D.3
Veach, D.4
Clarkson, B.5
Manova, K.6
Giancotti, F.G.7
Antonescu, C.R.8
Besmer, P.9
-
42
-
-
58649094197
-
Changes in the structure and function of ICC networks in ICC hyperplasia and gastrointestinal stromal tumors
-
Kwon, J.G., Hwang, S.J., Hennig, G.W., Bayguinov, Y., McCann, C., Chen, H., Rossi, F., Besmer, P., Sanders, K.M. and Ward, S.M. (2009) Changes in the structure and function of ICC networks in ICC hyperplasia and gastrointestinal stromal tumors. Gastroenterology, 136, 630-639.
-
(2009)
Gastroenterology
, vol.136
, pp. 630-639
-
-
Kwon, J.G.1
Hwang, S.J.2
Hennig, G.W.3
Bayguinov, Y.4
Mccann, C.5
Chen, H.6
Rossi, F.7
Besmer, P.8
Sanders, K.M.9
Ward, S.M.10
-
43
-
-
1642458352
-
c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways
-
Hong, L., Munugalavadla, V. and Kapur, R. (2004) c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways. Mol. Cell. Biol., 24, 1401-1410.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 1401-1410
-
-
Hong, L.1
Munugalavadla, V.2
Kapur, R.3
-
44
-
-
77957943127
-
ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours
-
Chi, P., Chen, Y., Zhang, L., Guo, X., Wongvipat, J., Shamu, T., Fletcher, J.A., Dewell, S., Maki, R.G., Zheng, D. et al. (2010) ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours. Nature, 467, 849-853.
-
(2010)
Nature
, vol.467
, pp. 849-853
-
-
Chi, P.1
Chen, Y.2
Zhang, L.3
Guo, X.4
Wongvipat, J.5
Shamu, T.6
Fletcher, J.A.7
Dewell, S.8
Maki, R.G.9
Zheng, D.10
-
45
-
-
36749030022
-
KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway
-
Bauer, S., Duensing, A., Demetri, G.D. and Fletcher, J.A. (2007) KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway. Oncogene, 26, 7560-7568.
-
(2007)
Oncogene
, vol.26
, pp. 7560-7568
-
-
Bauer, S.1
Duensing, A.2
Demetri, G.D.3
Fletcher, J.A.4
-
46
-
-
64349098673
-
Proapoptotic effects of lindane on mouse primordial germ cells
-
La Sala, G., Farini, D. and De Felici, M. (2009) Proapoptotic effects of lindane on mouse primordial germ cells. Toxicol. Sci., 108, 445-451.
-
(2009)
Toxicol. Sci.
, vol.108
, pp. 445-451
-
-
Sala, G.L.1
Farini, D.2
Felici, M.D.3
-
47
-
-
42149176654
-
AKT signaling promotes 326 Human Molecular Genetics, 2013
-
Kimura, T., Tomooka, M., Yamano, N., Murayama, K., Matoba, S., Umehara, H., Kanai, Y. and Nakano, T. (2008) AKT signaling promotes 326 Human Molecular Genetics, 2013, Vol. 22, No. 2derivation of embryonic germ cells from primordial germ cells. Development, 135, 869-879.
-
(2008)
derivation of embryonic germ cells from primordial germ cells. Development
, vol.22
, Issue.2
, pp. 869-879
-
-
Kimura, T.1
Tomooka, M.2
Yamano, N.3
Murayama, K.4
Matoba, S.5
Umehara, H.6
Kanai, Y.7
Nakano, T.8
-
48
-
-
0036679127
-
Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer
-
De Miguel, M.P., Cheng, L., Holland, E.C., Federspiel, M.J. and Donovan, P.J. (2002) Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer. Proc. Natl Acad. Sci. USA, 99, 10458-10463.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 10458-10463
-
-
Miguel, M.P.D.1
Cheng, L.2
Holland, E.C.3
Federspiel, M.J.4
Donovan, P.J.5
-
49
-
-
0038067837
-
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production
-
Kimura, T., Suzuki, A., Fujita, Y., Yomogida, K., Lomeli, H., Asada, N., Ikeuchi, M., Nagy, A., Mak, T.W. and Nakano, T. (2003) Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production. Development, 130, 1691-1700.
-
(2003)
Development
, vol.130
, pp. 1691-1700
-
-
Kimura, T.1
Suzuki, A.2
Fujita, Y.3
Yomogida, K.4
Lomeli, H.5
Asada, N.6
Ikeuchi, M.7
Nagy, A.8
Mak, T.W.9
Nakano, T.10
-
50
-
-
33749461709
-
Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor
-
Bauer, S., Yu, L.K., Demetri, G.D. and Fletcher, J.A. (2006) Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor. Cancer Res., 66, 9153-9161.
-
(2006)
Cancer Res.
, vol.66
, pp. 9153-9161
-
-
Bauer, S.1
Yu, L.K.2
Demetri, G.D.3
Fletcher, J.A.4
-
51
-
-
33845751024
-
Neoplasia driven by mutant c-KIT is mediated by intracellular, not plasma membrane, receptor signaling
-
Xiang, Z., Kreisel, F., Cain, J., Colson, A. and Tomasson, M.H. (2007) Neoplasia driven by mutant c-KIT is mediated by intracellular, not plasma membrane, receptor signaling. Mol. Cell. Biol., 27, 267-282.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 267-282
-
-
Xiang, Z.1
Kreisel, F.2
Cain, J.3
Colson, A.4
Tomasson, M.H.5
-
52
-
-
77954649854
-
Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state
-
Leitch, H.G., Blair, K., Mansfield, W., Ayetey, H., Humphreys, P., Nichols, J., Surani, M.A. and Smith, A. (2010) Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state. Development, 137, 2279-2287.
-
(2010)
Development
, vol.137
, pp. 2279-2287
-
-
Leitch, H.G.1
Blair, K.2
Mansfield, W.3
Ayetey, H.4
Humphreys, P.5
Nichols, J.6
Surani, M.A.7
Smith, A.8
-
53
-
-
0037230304
-
Activation of the JNK signaling pathway: breaking the brake on apoptosis
-
Lin, A. (2003) Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays, 25, 17-24.
-
(2003)
Bioessays
, vol.25
, pp. 17-24
-
-
Lin, A.1
-
54
-
-
0030840413
-
Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway
-
Logan, S.K., Falasca, M., Hu, P. and Schlessinger, J. (1997) Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway. Mol. Cell. Biol., 17, 5784-5790.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5784-5790
-
-
Logan, S.K.1
Falasca, M.2
Hu, P.3
Schlessinger, J.4
-
55
-
-
4644241746
-
The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis
-
Weston, C.R., Wong, A., Hall, J.P., Goad, M.E., Flavell, R.A. and Davis, R.J. (2004) The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc. Natl Acad. Sci. USA, 101, 14114-14119.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 14114-14119
-
-
Weston, C.R.1
Wong, A.2
Hall, J.P.3
Goad, M.E.4
Flavell, R.A.5
Davis, R.J.6
-
56
-
-
1242316958
-
JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD
-
Yu, C., Minemoto, Y., Zhang, J., Liu, J., Tang, F., Bui, T.N., Xiang, J. and Lin, A. (2004) JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. Mol. Cell, 13, 329-340.
-
(2004)
Mol. Cell
, vol.13
, pp. 329-340
-
-
Yu, C.1
Minemoto, Y.2
Zhang, J.3
Liu, J.4
Tang, F.5
Bui, T.N.6
Xiang, J.7
Lin, A.8
-
57
-
-
84655167578
-
A chromatin-modifying function of JNK during stem cell differentiation
-
Tiwari, V.K., Stadler, M.B., Wirbelauer, C., Paro, R., Schubeler, D. and Beisel, C. (2011) A chromatin-modifying function of JNK during stem cell differentiation. Nat. Genet., 44, 94-100.
-
(2011)
Nat. Genet.
, vol.44
, pp. 94-100
-
-
Tiwari, V.K.1
Stadler, M.B.2
Wirbelauer, C.3
Paro, R.4
Schubeler, D.5
Beisel, C.6
-
58
-
-
2542520755
-
Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)
-
Duensing, A., Medeiros, F., McConarty, B., Joseph, N.E., Panigrahy, D., Singer, S., Fletcher, C.D., Demetri, G.D. and Fletcher, J.A. (2004) Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs). Oncogene, 23, 3999-4006.
-
(2004)
Oncogene
, vol.23
, pp. 3999-4006
-
-
Duensing, A.1
Medeiros, F.2
Mcconarty, B.3
Joseph, N.E.4
Panigrahy, D.5
Singer, S.6
Fletcher, C.D.7
Demetri, G.D.8
Fletcher, J.A.9
-
59
-
-
0036275755
-
Allele-specific expression of imprinted genes in mouse migratory primordial germ cells
-
Szabo, P.E., Hubner, K., Scholer, H. and Mann, J.R. (2002) Allele-specific expression of imprinted genes in mouse migratory primordial germ cells. Mech. Dev., 115, 157-160.
-
(2002)
Mech. Dev.
, vol.115
, pp. 157-160
-
-
Szabo, P.E.1
Hubner, K.2
Scholer, H.3
Mann, J.R.4
-
60
-
-
0032938813
-
A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo
-
Yamaguchi, T.P., Bradley, A., McMahon, A.P. and Jones, S. (1999) A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development, 126, 1211-1223.
-
(1999)
Development
, vol.126
, pp. 1211-1223
-
-
Yamaguchi, T.P.1
Bradley, A.2
Mcmahon, A.P.3
Jones, S.4
-
61
-
-
0034004353
-
The onset of germ cell migration in the mouse embryo
-
Anderson, R., Copeland, T.K., Scholer, H., Heasman, J. and Wylie, C. (2000) The onset of germ cell migration in the mouse embryo. Mech. Dev., 91, 61-68.
-
(2000)
Mech. Dev.
, vol.91
, pp. 61-68
-
-
Anderson, R.1
Copeland, T.K.2
Scholer, H.3
Heasman, J.4
Wylie, C.5
|