-
1
-
-
0034772197
-
A policy for leishmaniasis with respect to the prevention and control of drug resistance
-
Bryceson A, (2001) A policy for leishmaniasis with respect to the prevention and control of drug resistance. Trop Med Int Health 6: 928-934.
-
(2001)
Trop Med Int Health
, vol.6
, pp. 928-934
-
-
Bryceson, A.1
-
2
-
-
0025331743
-
Treatment of visceral leishmaniasis in Kenya by aminosidine alone or combined with sodium stibogluconate
-
Chunge CN, Owate J, Pamba HO, Donno L, (1990) Treatment of visceral leishmaniasis in Kenya by aminosidine alone or combined with sodium stibogluconate. Trans R Soc Trop Med Hyg 84: 221-225.
-
(1990)
Trans R Soc Trop Med Hyg
, vol.84
, pp. 221-225
-
-
Chunge, C.N.1
Owate, J.2
Pamba, H.O.3
Donno, L.4
-
3
-
-
28044469320
-
Treatment options for visceral leishmaniasis: a systematic review of clinical studies done in India, 1980-2004
-
Olliaro PL, Guerin PJ, Gerstl S, Haaskjold AA, Rottingen JA, et al. (2005) Treatment options for visceral leishmaniasis: a systematic review of clinical studies done in India, 1980-2004. Lancet Infect Dis 5: 763-774.
-
(2005)
Lancet Infect Dis
, vol.5
, pp. 763-774
-
-
Olliaro, P.L.1
Guerin, P.J.2
Gerstl, S.3
Haaskjold, A.A.4
Rottingen, J.A.5
-
4
-
-
53349151814
-
New treatment approach in Indian visceral leishmaniasis: single-dose liposomal amphotericin B followed by short-course oral miltefosine
-
Sundar S, Rai M, Chakravarty J, Agarwal D, Agarwal N, et al. (2008) New treatment approach in Indian visceral leishmaniasis: single-dose liposomal amphotericin B followed by short-course oral miltefosine. Clin Infect Dis 47: 1000-1006.
-
(2008)
Clin Infect Dis
, vol.47
, pp. 1000-1006
-
-
Sundar, S.1
Rai, M.2
Chakravarty, J.3
Agarwal, D.4
Agarwal, N.5
-
5
-
-
78149258813
-
Cost-effectiveness analysis of combination therapies for visceral leishmaniasis in the Indian subcontinent
-
Meheus F, Balasegaram M, Olliaro P, Sundar S, Suman R, et al. (2010) Cost-effectiveness analysis of combination therapies for visceral leishmaniasis in the Indian subcontinent. PLoS Negl Trop Dis 4: e818.
-
(2010)
PLoS Negl Trop Dis
, vol.4
-
-
Meheus, F.1
Balasegaram, M.2
Olliaro, P.3
Sundar, S.4
Suman, R.5
-
6
-
-
79551683357
-
Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial
-
Sundar S, Sinha PK, Rai M, Verma DK, Nawin K, et al. (2011) Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial. Lancet 377: 477-486.
-
(2011)
Lancet
, vol.377
, pp. 477-486
-
-
Sundar, S.1
Sinha, P.K.2
Rai, M.3
Verma, D.K.4
Nawin, K.5
-
7
-
-
84861665791
-
WHO Leishmaniasis control team. Leishmaniasis worldwide and global estimates of its incidence
-
Alvar J, Vélez ID, Bern C, Herrero M, Desjeux P, et al. (2012) WHO Leishmaniasis control team. Leishmaniasis worldwide and global estimates of its incidence. PLoS One 7: e35671.
-
(2012)
PLoS One
, vol.7
-
-
Alvar, J.1
Vélez, I.D.2
Bern, C.3
Herrero, M.4
Desjeux, P.5
-
8
-
-
77955333692
-
New antileishmanial candidates and lead compounds
-
Richard JV, Werbovetz KA, (2010) New antileishmanial candidates and lead compounds. Curr Opin Chem Biol 14: 447-455.
-
(2010)
Curr Opin Chem Biol
, vol.14
, pp. 447-455
-
-
Richard, J.V.1
Werbovetz, K.A.2
-
9
-
-
0034780949
-
Drug resistance in Indian visceral leishmaniasis
-
Sundar S, (2001) Drug resistance in Indian visceral leishmaniasis. Trop Med Int Health 6: 840-854.
-
(2001)
Trop Med Int Health
, vol.6
, pp. 840-854
-
-
Sundar, S.1
-
10
-
-
78349260454
-
Drug combinations for visceral leishmaniasis
-
Olliaro PL, (2010) Drug combinations for visceral leishmaniasis. Curr Opin Infect Dis 23: 595-602.
-
(2010)
Curr Opin Infect Dis
, vol.23
, pp. 595-602
-
-
Olliaro, P.L.1
-
11
-
-
29944439964
-
In vitro and in vivo interactions between miltefosine and othe antileishmanial drugs
-
Seifert K, Croft SL, (2006) In vitro and in vivo interactions between miltefosine and othe antileishmanial drugs. Antim Agents Chemother 50: 73-79.
-
(2006)
Antim Agents Chemother
, vol.50
, pp. 73-79
-
-
Seifert, K.1
Croft, S.L.2
-
12
-
-
79959679843
-
Safety and Efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East Africa: study protocol for a randomized controlled trial
-
Omollo R, Alexander N, Edwards T, Khalil EA, Younis BM, et al. (2011) Safety and Efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East Africa: study protocol for a randomized controlled trial. Trials 12: 166.
-
(2011)
Trials
, vol.12
, pp. 166
-
-
Omollo, R.1
Alexander, N.2
Edwards, T.3
Khalil, E.A.4
Younis, B.M.5
-
13
-
-
77049105214
-
Combination therapy for visceral leishmaniasis
-
van Griensven J, Balasegaram M, Meheus F, Alvar J, Lynen L, et al. (2010) Combination therapy for visceral leishmaniasis. Lancet Infect Dis 10: 184-194.
-
(2010)
Lancet Infect Dis
, vol.10
, pp. 184-194
-
-
van Griensven, J.1
Balasegaram, M.2
Meheus, F.3
Alvar, J.4
Lynen, L.5
-
14
-
-
0344333486
-
Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line
-
Chiquero MJ, Perez-Victoria JM, O'Valle F, González-Ros JM, del Moral RG, et al. (1998) Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line. Biochem Pharmacol 55: 131-139.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 131-139
-
-
Chiquero, M.J.1
Perez-Victoria, J.M.2
O'Valle, F.3
González-Ros, J.M.4
del Moral, R.G.5
-
15
-
-
0141457689
-
Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine)
-
Seifert K, Matu S, Pérez-Victoria F, Castany S, Gamarro F, et al. (2003) Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). Int J Antimicrob Agents 22: 380-387.
-
(2003)
Int J Antimicrob Agents
, vol.22
, pp. 380-387
-
-
Seifert, K.1
Matu, S.2
Pérez-Victoria, F.3
Castany, S.4
Gamarro, F.5
-
16
-
-
0035924221
-
Chemosensitization of a multidrug-resistant Leishmania tropica line by new sesquiterpenes from Maytenus magellanica and Maytenus chubutensis
-
Kennedy ML, Cortés-Selva F, Pérez-Victoria JM, Jiménez IA, González AG, et al. (2001) Chemosensitization of a multidrug-resistant Leishmania tropica line by new sesquiterpenes from Maytenus magellanica and Maytenus chubutensis. J Med Chem 44: 4668-4676.
-
(2001)
J Med Chem
, vol.44
, pp. 4668-4676
-
-
Kennedy, M.L.1
Cortés-Selva, F.2
Pérez-Victoria, J.M.3
Jiménez, I.A.4
González, A.G.5
-
17
-
-
34547337720
-
Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo
-
Seifert K, Pérez-Victoria FJ, Stettler M, Sánchez-Cañete MP, Castanys S, et al. (2007) Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo. Int J Antimicrob Agents 30: 229-235.
-
(2007)
Int J Antimicrob Agents
, vol.30
, pp. 229-235
-
-
Seifert, K.1
Pérez-Victoria, F.J.2
Stettler, M.3
Sánchez-Cañete, M.P.4
Castanys, S.5
-
18
-
-
67449146892
-
Flow cytometric determination of intracellular non-protein thiols in Leishmania promastiotes using 5-chloromethyl fluorescein diacetate
-
Sarkar A, Mandal G, Singh N, Sundar S, Chatterjee M, (2009) Flow cytometric determination of intracellular non-protein thiols in Leishmania promastiotes using 5-chloromethyl fluorescein diacetate. Exp Parasitol 122: 299-305.
-
(2009)
Exp Parasitol
, vol.122
, pp. 299-305
-
-
Sarkar, A.1
Mandal, G.2
Singh, N.3
Sundar, S.4
Chatterjee, M.5
-
19
-
-
79952356991
-
Increased glycolytic ATP synthesis is associated with Tafenoquine resistance in Leishmania major
-
Manzano JI, Carvalho L, Pérez-Victoria JM, Castanys S, Gamarro F, (2011) Increased glycolytic ATP synthesis is associated with Tafenoquine resistance in Leishmania major. Antimicrob Agents Chemother 55: 1045-1052.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 1045-1052
-
-
Manzano, J.I.1
Carvalho, L.2
Pérez-Victoria, J.M.3
Castanys, S.4
Gamarro, F.5
-
20
-
-
78649644451
-
Tafenoquine, an antiplasmodial 8-aminoquinoline, targets Leishmania respiratory Complex III and induces apoptosis
-
Carvalho L, Luque-Ortega JR, Manzano JI, Castanys S, Rivas L, et al. (2010) Tafenoquine, an antiplasmodial 8-aminoquinoline, targets Leishmania respiratory Complex III and induces apoptosis. Antimicrob Agents Chemother 54: 5344-5351.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 5344-5351
-
-
Carvalho, L.1
Luque-Ortega, J.R.2
Manzano, J.I.3
Castanys, S.4
Rivas, L.5
-
21
-
-
0029841913
-
Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania
-
Mukhopadhyay R, Dey S, Xu N, Gade D, Lightbody J, et al. (1996) Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania. Proc Natl Acad Sci USA 93: 10383-10387.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10383-10387
-
-
Mukhopadhyay, R.1
Dey, S.2
Xu, N.3
Gade, D.4
Lightbody, J.5
-
22
-
-
80053395366
-
Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania
-
doi:10.1038
-
Moreira W, Leprohon P, Ouellette M, (2011) Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania. Cell Death Dis doi: 10.1038.
-
(2011)
Cell Death Dis
-
-
Moreira, W.1
Leprohon, P.2
Ouellette, M.3
-
23
-
-
0029064954
-
Ribosomes of Leishmania are a target for the aminoglycosides
-
Maarouf M, Lawrence F, Croft SL, Robert-Gero M, (1995) Ribosomes of Leishmania are a target for the aminoglycosides. Parasitol Res 81: 421-425.
-
(1995)
Parasitol Res
, vol.81
, pp. 421-425
-
-
Maarouf, M.1
Lawrence, F.2
Croft, S.L.3
Robert-Gero, M.4
-
24
-
-
0031149815
-
In vivo interference of paromomycin with mitochondrial activity of Leishmania
-
Maarouf M, de Kouchkovsky Y, Brown S, Petit PX, Robert-Gero M, (1997) In vivo interference of paromomycin with mitochondrial activity of Leishmania. Exp Cell Res 232: 339-348.
-
(1997)
Exp Cell Res
, vol.232
, pp. 339-348
-
-
Maarouf, M.1
de Kouchkovsky, Y.2
Brown, S.3
Petit, P.X.4
Robert-Gero, M.5
-
25
-
-
0030975596
-
Inhibition of the respiratory chain results in a reversible metabolic arrest in Leishmania promastigotes
-
Van Hellemond JJ, Tielens AG, (1997) Inhibition of the respiratory chain results in a reversible metabolic arrest in Leishmania promastigotes. Mol Biochem Parasitol 85: 135-138.
-
(1997)
Mol Biochem Parasitol
, vol.85
, pp. 135-138
-
-
Van Hellemond, J.J.1
Tielens, A.G.2
-
26
-
-
84863711529
-
Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol
-
Hendrickx S, Inocêncio da Luz R, Bhandari V, Kuypers K, Shaw CD, et al. (2012) Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol. PLoS Negl Trop Dis 6: e1664.
-
(2012)
PLoS Negl Trop Dis
, vol.6
-
-
Hendrickx, S.1
Inocêncio da Luz, R.2
Bhandari, V.3
Kuypers, K.4
Shaw, C.D.5
-
27
-
-
84857852404
-
Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background
-
Decuypere S, Vanaerschot M, Brunker K, Imamura H, Müller S, et al. (2012) Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background. PLoS Negl Trop Dis 6: e1514.
-
(2012)
PLoS Negl Trop Dis
, vol.6
-
-
Decuypere, S.1
Vanaerschot, M.2
Brunker, K.3
Imamura, H.4
Müller, S.5
-
28
-
-
84863652183
-
Drug susceptibility in Leishmania isolates following miltefosine treatment in cases of visceral leishmaniasis and post kala-azar dermal leishmaniasis
-
Bhandari V, Kulshrestha A, Deep DK, Stark O, Prajapati VK, et al. (2012) Drug susceptibility in Leishmania isolates following miltefosine treatment in cases of visceral leishmaniasis and post kala-azar dermal leishmaniasis. PLoS Negl Trop Dis 6: e1657.
-
(2012)
PLoS Negl Trop Dis
, vol.6
-
-
Bhandari, V.1
Kulshrestha, A.2
Deep, D.K.3
Stark, O.4
Prajapati, V.K.5
-
29
-
-
77950330640
-
In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent
-
Seifert K, Escobar P, Croft SL, (2010) In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent. J Antimicrob Chemother 65: 508-511.
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 508-511
-
-
Seifert, K.1
Escobar, P.2
Croft, S.L.3
-
30
-
-
70349131162
-
In vitro susceptibilities of Leishmania donovani promastigote and amastigote stages to antileishmanial reference drugs: practical relevance of stage-specific differences
-
Vermeersch M, da Luz RI, Toté K, Timmermans JP, Cos P, et al. (2009) In vitro susceptibilities of Leishmania donovani promastigote and amastigote stages to antileishmanial reference drugs: practical relevance of stage-specific differences. Antimicrob Agents Chemother 53: 3855-3859.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 3855-3859
-
-
Vermeersch, M.1
da Luz, R.I.2
Toté, K.3
Timmermans, J.P.4
Cos, P.5
-
31
-
-
0031893745
-
Mechanism of Amphotericin B resistance in Leishmania donovani promastigotes
-
Mbongo N, Loiseau PM, Billion MA, Robert-Gero M, (1998) Mechanism of Amphotericin B resistance in Leishmania donovani promastigotes. Antimicrob Agents Chemother 42: 352-357.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 352-357
-
-
Mbongo, N.1
Loiseau, P.M.2
Billion, M.A.3
Robert-Gero, M.4
-
32
-
-
33745253122
-
Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use
-
Pérez-Victoria FJ, Sánchez-Cañete MP, Seifert K, Croft SL, Sundar S, et al. (2006) Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use. Drug Resist Updat 9: 26-39.
-
(2006)
Drug Resist Updat
, vol.9
, pp. 26-39
-
-
Pérez-Victoria, F.J.1
Sánchez-Cañete, M.P.2
Seifert, K.3
Croft, S.L.4
Sundar, S.5
|