메뉴 건너뛰기




Volumn 122, Issue 4, 2009, Pages 299-305

Flow cytometric determination of intracellular non-protein thiols in Leishmania promastigotes using 5-chloromethyl fluorescein diacetate

Author keywords

Antileishmanial; Antimony resistance; CMFDA; Leishmaniasis; Promastigotes; Thiols

Indexed keywords

5 CHLOROMETHYL FLUORESCEIN DIACETATE; ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; ANTIMONY; ANTIOXIDANT; BUTHIONINE SULFOXIMINE; CATALASE; CYSTEINE; DIAMIDE; DYE; MILTEFOSINE; N ETHYLMALEIMIDE; NON PROTEIN THIOL; THIOL; UNCLASSIFIED DRUG;

EID: 67449146892     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2009.04.012     Document Type: Article
Times cited : (41)

References (43)
  • 2
    • 0028822932 scopus 로고
    • New mechanisms of drug resistance in parasitic protozoa
    • Borst P., and Ouellette M. New mechanisms of drug resistance in parasitic protozoa. Annual Review of Microbiology 49 (1995) 427-460
    • (1995) Annual Review of Microbiology , vol.49 , pp. 427-460
    • Borst, P.1    Ouellette, M.2
  • 4
    • 34249787648 scopus 로고    scopus 로고
    • A novel ATP-binding cassette transporter from Leishmania is involved in transport of phosphatidylcholine analogues and resistance to alkyl-phospholipids
    • Castanys-Muñoz E., Alder-Baerens N., Pomorski T., Gamarro F., and Castanys S. A novel ATP-binding cassette transporter from Leishmania is involved in transport of phosphatidylcholine analogues and resistance to alkyl-phospholipids. Molecular Microbiology 64 (2007) 1141-1153
    • (2007) Molecular Microbiology , vol.64 , pp. 1141-1153
    • Castanys-Muñoz, E.1    Alder-Baerens, N.2    Pomorski, T.3    Gamarro, F.4    Castanys, S.5
  • 5
    • 0029658379 scopus 로고    scopus 로고
    • 2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes
    • 2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes. Japanese Journal of Pharmacology 71 (1996) 299-305
    • (1996) Japanese Journal of Pharmacology , vol.71 , pp. 299-305
    • Chikahisa, L.1    Oyama, Y.2    Okazaki, E.3    Noda, K.4
  • 6
    • 0142106997 scopus 로고    scopus 로고
    • Functional genetic identification of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major
    • Coelho A.C., Beverley S.M., and Cotrim P.C. Functional genetic identification of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major. Molecular and Biochemical Parasitology 130 (2003) 83-90
    • (2003) Molecular and Biochemical Parasitology , vol.130 , pp. 83-90
    • Coelho, A.C.1    Beverley, S.M.2    Cotrim, P.C.3
  • 7
    • 0025890981 scopus 로고
    • Differential specificity of monochlorobimane for isozymes of human and rodent glutathione S-transferases
    • Cook J.A., Iype S.N., and Mitchell J.B. Differential specificity of monochlorobimane for isozymes of human and rodent glutathione S-transferases. Cancer Research 51 (1991) 1606-1612
    • (1991) Cancer Research , vol.51 , pp. 1606-1612
    • Cook, J.A.1    Iype, S.N.2    Mitchell, J.B.3
  • 8
    • 0034672943 scopus 로고    scopus 로고
    • Metabolism and functions of glutathione in brain
    • Dringen R. Metabolism and functions of glutathione in brain. Progress in Neurobiology 62 (2000) 649-671
    • (2000) Progress in Neurobiology , vol.62 , pp. 649-671
    • Dringen, R.1
  • 9
    • 0022002912 scopus 로고
    • Trypanothione: a novel bis(glutathionyl)-spermidine cofactor for glutathione reductase in trypanosomatids
    • Fairlamb A.H., Blackburn P., Ulrich P., Chait B.T., and Cerami A. Trypanothione: a novel bis(glutathionyl)-spermidine cofactor for glutathione reductase in trypanosomatids. Science 227 (1985) 1485-1487
    • (1985) Science , vol.227 , pp. 1485-1487
    • Fairlamb, A.H.1    Blackburn, P.2    Ulrich, P.3    Chait, B.T.4    Cerami, A.5
  • 10
    • 0026793462 scopus 로고
    • Metabolism and functions of trypanothione in the Kinetoplastida
    • Fairlamb A.H., and Cerami A. Metabolism and functions of trypanothione in the Kinetoplastida. Annual Review of Microbiology 46 (1992) 695-729
    • (1992) Annual Review of Microbiology , vol.46 , pp. 695-729
    • Fairlamb, A.H.1    Cerami, A.2
  • 11
    • 0033230579 scopus 로고    scopus 로고
    • Glutathione and trypanothione in parasitic hydroperoxide metabolism
    • Flohé L., Hecht H.J., and Steinert P. Glutathione and trypanothione in parasitic hydroperoxide metabolism. Free Radical Biology and Medicine 27 (1999) 966-984
    • (1999) Free Radical Biology and Medicine , vol.27 , pp. 966-984
    • Flohé, L.1    Hecht, H.J.2    Steinert, P.3
  • 13
    • 0037328022 scopus 로고    scopus 로고
    • Role of superoxide dismutase in survival of Leishmania within the macrophage
    • Ghosh S., Goswami S., and Adhya S. Role of superoxide dismutase in survival of Leishmania within the macrophage. The Biochemical Journal 369 (2003) 447-452
    • (2003) The Biochemical Journal , vol.369 , pp. 447-452
    • Ghosh, S.1    Goswami, S.2    Adhya, S.3
  • 14
    • 0018666729 scopus 로고
    • Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
    • Griffith O.W., and Meister A. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). The Journal of Biological Chemistry 254 (1979) 7558-7560
    • (1979) The Journal of Biological Chemistry , vol.254 , pp. 7558-7560
    • Griffith, O.W.1    Meister, A.2
  • 16
    • 0028325262 scopus 로고
    • Evaluation of methods for measuring cellular glutathione content using flow cytometry
    • Hedley D.W., and Chow S. Evaluation of methods for measuring cellular glutathione content using flow cytometry. Cytometry 15 (1994) 349-358
    • (1994) Cytometry , vol.15 , pp. 349-358
    • Hedley, D.W.1    Chow, S.2
  • 17
    • 0027494350 scopus 로고
    • Phenotype of recombinant Leishmania donovani and Trypanosoma cruzi which over-express trypanothione reductase. Sensitivity towards agents that are thought to induce oxidative stress
    • Kelly J.M., Taylor M.C., Smith K., Hunter K.J., and Fairlamb A.H. Phenotype of recombinant Leishmania donovani and Trypanosoma cruzi which over-express trypanothione reductase. Sensitivity towards agents that are thought to induce oxidative stress. European Journal of Biochemistry 218 (1993) 29-37
    • (1993) European Journal of Biochemistry , vol.218 , pp. 29-37
    • Kelly, J.M.1    Taylor, M.C.2    Smith, K.3    Hunter, K.J.4    Fairlamb, A.H.5
  • 18
    • 0035065855 scopus 로고    scopus 로고
    • Rapid reduction of intracellular glutathione in human bronchial epithelial cells exposed to occupational levels of toluene diisocyanate
    • Lantz R.C., Lemus R., Lange R.W., and Karol M.H. Rapid reduction of intracellular glutathione in human bronchial epithelial cells exposed to occupational levels of toluene diisocyanate. Toxicological Sciences 60 (2001) 348-355
    • (2001) Toxicological Sciences , vol.60 , pp. 348-355
    • Lantz, R.C.1    Lemus, R.2    Lange, R.W.3    Karol, M.H.4
  • 19
    • 34948899791 scopus 로고    scopus 로고
    • Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony
    • Mandal G., Wyllie S., Singh N., Sundar S., Fairlamb A.H., and Chatterjee M. Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony. Parasitology 134 (2007) 1679-1687
    • (2007) Parasitology , vol.134 , pp. 1679-1687
    • Mandal, G.1    Wyllie, S.2    Singh, N.3    Sundar, S.4    Fairlamb, A.H.5    Chatterjee, M.6
  • 24
    • 33646456171 scopus 로고    scopus 로고
    • Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani infected macrophages
    • Mookerjee Basu J., Mookerjee A., Sen P., Bhaumik S., Sen P., Banerjee S., Naskar K., Choudhuri S.K., Saha B., Raha S., and Roy S. Sodium antimony gluconate induces generation of reactive oxygen species and nitric oxide via phosphoinositide 3-kinase and mitogen-activated protein kinase activation in Leishmania donovani infected macrophages. Antimicrobial Agents and Chemotherapy 50 (2006) 1788-1797
    • (2006) Antimicrobial Agents and Chemotherapy , vol.50 , pp. 1788-1797
    • Mookerjee Basu, J.1    Mookerjee, A.2    Sen, P.3    Bhaumik, S.4    Sen, P.5    Banerjee, S.6    Naskar, K.7    Choudhuri, S.K.8    Saha, B.9    Raha, S.10    Roy, S.11
  • 30
    • 0024119576 scopus 로고
    • A flow cytometric assay for intracellular nonprotein thiols using mercury orange
    • O'Connor J.E., Kimler B.F., Morgan M.C., and Tempas K.J. A flow cytometric assay for intracellular nonprotein thiols using mercury orange. Cytometry 9 (1988) 529-532
    • (1988) Cytometry , vol.9 , pp. 529-532
    • O'Connor, J.E.1    Kimler, B.F.2    Morgan, M.C.3    Tempas, K.J.4
  • 31
    • 0031455412 scopus 로고    scopus 로고
    • Cloning, characterization and overexpression of two iron superoxide dismutase cDNAs from Leishmania chagasi: role in pathogenesis
    • Paramchuk W.J., Ismail S.O., Bhatia A., and Gedamu L. Cloning, characterization and overexpression of two iron superoxide dismutase cDNAs from Leishmania chagasi: role in pathogenesis. Molecular and Biochemical Parasitology 90 (1997) 203-221
    • (1997) Molecular and Biochemical Parasitology , vol.90 , pp. 203-221
    • Paramchuk, W.J.1    Ismail, S.O.2    Bhatia, A.3    Gedamu, L.4
  • 32
    • 0025877058 scopus 로고
    • Flow cytometric analysis of cell cycle-dependent changes in cell thiol level by combining a new laser dye with Hoechst 33342
    • Poot M., Kavanagh T.J., Kang H.C., Haugland R.P., and Rabinovitch P.S. Flow cytometric analysis of cell cycle-dependent changes in cell thiol level by combining a new laser dye with Hoechst 33342. Cytometry 12 (1991) 184-187
    • (1991) Cytometry , vol.12 , pp. 184-187
    • Poot, M.1    Kavanagh, T.J.2    Kang, H.C.3    Haugland, R.P.4    Rabinovitch, P.S.5
  • 34
    • 0038544289 scopus 로고    scopus 로고
    • Evaluation of fluorescent dyes for measuring intracellular glutathione content in primary cultures of human neurons and neuroblastoma SH-SY5Y
    • Sebastià J., Cristòfol R., Martín M., Rodríguez-Farré E., and Sanfeliu C. Evaluation of fluorescent dyes for measuring intracellular glutathione content in primary cultures of human neurons and neuroblastoma SH-SY5Y. Cytometry A 51 (2003) 16-25
    • (2003) Cytometry A , vol.51 , pp. 16-25
    • Sebastià, J.1    Cristòfol, R.2    Martín, M.3    Rodríguez-Farré, E.4    Sanfeliu, C.5
  • 35
    • 0023832140 scopus 로고
    • Levels of polyamines, glutathione and glutathione-spermidine conjugates during growth of the insect trypanosomatid Crithidia fasciculata
    • Shim H., and Fairlamb A.H. Levels of polyamines, glutathione and glutathione-spermidine conjugates during growth of the insect trypanosomatid Crithidia fasciculata. Journal of General Microbiology 134 (1988) 807-817
    • (1988) Journal of General Microbiology , vol.134 , pp. 807-817
    • Shim, H.1    Fairlamb, A.H.2
  • 36
    • 0033230043 scopus 로고    scopus 로고
    • Glutathione and its role in cellular functions
    • Sies H. Glutathione and its role in cellular functions. Free Radical Biology and Medicine 27 (1999) 916-921
    • (1999) Free Radical Biology and Medicine , vol.27 , pp. 916-921
    • Sies, H.1
  • 39
    • 34548494139 scopus 로고    scopus 로고
    • Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity
    • Versteeg H.H., and Ruf W. Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity. The Journal of Biological Chemistry 282 (2007) 25416-25424
    • (2007) The Journal of Biological Chemistry , vol.282 , pp. 25416-25424
    • Versteeg, H.H.1    Ruf, W.2
  • 40
    • 3042641848 scopus 로고    scopus 로고
    • Trypanothione S-transferase activity in a trypanosomatid ribosomal elongation factor 1B
    • Vickers T.J., and Fairlamb A.H. Trypanothione S-transferase activity in a trypanosomatid ribosomal elongation factor 1B. The Journal of Biological Chemistry 279 (2004) 27246-27256
    • (2004) The Journal of Biological Chemistry , vol.279 , pp. 27246-27256
    • Vickers, T.J.1    Fairlamb, A.H.2
  • 41
    • 4544289321 scopus 로고    scopus 로고
    • Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani
    • Wyllie S., Cunningham M.L., and Fairlamb A.H. Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani. The Journal of Biological Chemistry 279 (2004) 39925-39932
    • (2004) The Journal of Biological Chemistry , vol.279 , pp. 39925-39932
    • Wyllie, S.1    Cunningham, M.L.2    Fairlamb, A.H.3
  • 42
    • 42049091432 scopus 로고    scopus 로고
    • Roles of trypanothione S-transferase and tryparedoxin peroxidase in resistance to antimonials
    • Wyllie S., Vickers T.J., and Fairlamb A.H. Roles of trypanothione S-transferase and tryparedoxin peroxidase in resistance to antimonials. Antimicrobial Agents and Chemotherapy 52 (2008) 1359-1365
    • (2008) Antimicrobial Agents and Chemotherapy , vol.52 , pp. 1359-1365
    • Wyllie, S.1    Vickers, T.J.2    Fairlamb, A.H.3
  • 43
    • 0028142514 scopus 로고
    • Localization of cytosolically oriented maleimide-reactive domain of vacuolar H(+)-pyrophosphatase
    • Zhen R.G., Kim E.J., and Rea P.A. Localization of cytosolically oriented maleimide-reactive domain of vacuolar H(+)-pyrophosphatase. Journal of Biological Chemistry 269 (1994) 23342-23350
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 23342-23350
    • Zhen, R.G.1    Kim, E.J.2    Rea, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.