메뉴 건너뛰기




Volumn 8, Issue 12, 2012, Pages

Reciprocal Signaling between the Ectoderm and a Mesendodermal Left-Right Organizer Directs Left-Right Determination in the Sea Urchin Embryo

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR;

EID: 84872020298     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003121     Document Type: Article
Times cited : (59)

References (112)
  • 1
    • 0034175652 scopus 로고    scopus 로고
    • Conserved and divergent mechanisms in left-right axis formation
    • Burdine RD, Schier AF, (2000) Conserved and divergent mechanisms in left-right axis formation. Genes Dev 14: 763-776.
    • (2000) Genes Dev , vol.14 , pp. 763-776
    • Burdine, R.D.1    Schier, A.F.2
  • 2
    • 9944241753 scopus 로고    scopus 로고
    • Left-right asymmetry in embryonic development: a comprehensive review
    • Levin M, (2005) Left-right asymmetry in embryonic development: a comprehensive review. Mech Dev 122: 3-25.
    • (2005) Mech Dev , vol.122 , pp. 3-25
    • Levin, M.1
  • 3
    • 0041845296 scopus 로고    scopus 로고
    • Cilia are at the heart of vertebrate left-right asymmetry
    • McGrath J, Brueckner M, (2003) Cilia are at the heart of vertebrate left-right asymmetry. Curr Opin Genet Dev 13: 385-392.
    • (2003) Curr Opin Genet Dev , vol.13 , pp. 385-392
    • McGrath, J.1    Brueckner, M.2
  • 4
    • 70349529877 scopus 로고    scopus 로고
    • Left-right asymmetry in gut development: what happens next?
    • Burn SF, Hill RE, (2009) Left-right asymmetry in gut development: what happens next? Bioessays 31: 1026-1037.
    • (2009) Bioessays , vol.31 , pp. 1026-1037
    • Burn, S.F.1    Hill, R.E.2
  • 5
    • 0041885055 scopus 로고    scopus 로고
    • Left-right asymmetry: nodal points
    • Mercola M, (2003) Left-right asymmetry: nodal points. J Cell Sci 116: 3251-3257.
    • (2003) J Cell Sci , vol.116 , pp. 3251-3257
    • Mercola, M.1
  • 6
    • 33646204913 scopus 로고    scopus 로고
    • Nodal flow and the generation of left-right asymmetry
    • Hirokawa N, Tanaka Y, Okada Y, Takeda S, (2006) Nodal flow and the generation of left-right asymmetry. Cell 125: 33-45.
    • (2006) Cell , vol.125 , pp. 33-45
    • Hirokawa, N.1    Tanaka, Y.2    Okada, Y.3    Takeda, S.4
  • 7
    • 70449670932 scopus 로고    scopus 로고
    • Disorders of left-right asymmetry: heterotaxy and situs inversus
    • Sutherland MJ, Ware SM, (2009) Disorders of left-right asymmetry: heterotaxy and situs inversus. Am J Med Genet C Semin Med Genet 151C: 307-317.
    • (2009) Am J Med Genet C Semin Med Genet , vol.151 C , pp. 307-317
    • Sutherland, M.J.1    Ware, S.M.2
  • 8
    • 0036843552 scopus 로고    scopus 로고
    • The evolution of left-right asymmetry in chordates
    • Boorman CJ, Shimeld SM, (2002) The evolution of left-right asymmetry in chordates. Bioessays 24: 1004-1011.
    • (2002) Bioessays , vol.24 , pp. 1004-1011
    • Boorman, C.J.1    Shimeld, S.M.2
  • 9
    • 0033978733 scopus 로고    scopus 로고
    • Left-right asymmetric expression of BbPtx, a Ptx-related gene, in a lancelet species and the developmental left-sidedness in deuterostomes
    • Yasui K, Zhang S, Uemura M, Saiga H, (2000) Left-right asymmetric expression of BbPtx, a Ptx-related gene, in a lancelet species and the developmental left-sidedness in deuterostomes. Development 127: 187-195.
    • (2000) Development , vol.127 , pp. 187-195
    • Yasui, K.1    Zhang, S.2    Uemura, M.3    Saiga, H.4
  • 10
    • 21344438625 scopus 로고    scopus 로고
    • Left-right asymmetry in the sea urchin embryo is regulated by Nodal signalling on the right side
    • Duboc V, Rottinger E, Besnardeau L, Lapraz F, Lepage T, (2005) Left-right asymmetry in the sea urchin embryo is regulated by Nodal signalling on the right side. Developmental Cell 9: 147-158.
    • (2005) Developmental Cell , vol.9 , pp. 147-158
    • Duboc, V.1    Rottinger, E.2    Besnardeau, L.3    Lapraz, F.4    Lepage, T.5
  • 11
    • 60549099164 scopus 로고    scopus 로고
    • Nodal signalling is involved in left-right asymmetry in snails
    • Grande C, Patel NH, (2009) Nodal signalling is involved in left-right asymmetry in snails. Nature 457: 1007-1011.
    • (2009) Nature , vol.457 , pp. 1007-1011
    • Grande, C.1    Patel, N.H.2
  • 13
    • 57149127744 scopus 로고    scopus 로고
    • The development and evolution of left-right asymmetry in invertebrates: lessons from Drosophila and snails
    • Okumura T, Utsuno H, Kuroda J, Gittenberger E, Asami T, et al. (2008) The development and evolution of left-right asymmetry in invertebrates: lessons from Drosophila and snails. Dev Dyn 237: 3497-3515.
    • (2008) Dev Dyn , vol.237 , pp. 3497-3515
    • Okumura, T.1    Utsuno, H.2    Kuroda, J.3    Gittenberger, E.4    Asami, T.5
  • 14
    • 0031128033 scopus 로고    scopus 로고
    • Left-right asymmetry in vertebrate embryogenesis
    • Levin M, (1997) Left-right asymmetry in vertebrate embryogenesis. Bioessays 19: 287-296.
    • (1997) Bioessays , vol.19 , pp. 287-296
    • Levin, M.1
  • 15
    • 0031769527 scopus 로고    scopus 로고
    • Molecular mechanisms of vertebrate left-right development
    • Ramsdell AF, Yost HJ, (1998) Molecular mechanisms of vertebrate left-right development. Trends Genet 14: 459-465.
    • (1998) Trends Genet , vol.14 , pp. 459-465
    • Ramsdell, A.F.1    Yost, H.J.2
  • 17
    • 66149094719 scopus 로고    scopus 로고
    • Cell movements at Hensen's node establish left/right asymmetric gene expression in the chick
    • Gros J, Feistel K, Viebahn C, Blum M, Tabin CJ, (2009) Cell movements at Hensen's node establish left/right asymmetric gene expression in the chick. Science 324: 941-944.
    • (2009) Science , vol.324 , pp. 941-944
    • Gros, J.1    Feistel, K.2    Viebahn, C.3    Blum, M.4    Tabin, C.J.5
  • 18
    • 0032707182 scopus 로고    scopus 로고
    • Gap junction-mediated transfer of left-right patterning signals in the early chick blastoderm is upstream of Shh asymmetry in the node
    • Levin M, Mercola M, (1999) Gap junction-mediated transfer of left-right patterning signals in the early chick blastoderm is upstream of Shh asymmetry in the node. Development 126: 4703-4714.
    • (1999) Development , vol.126 , pp. 4703-4714
    • Levin, M.1    Mercola, M.2
  • 19
    • 0037020041 scopus 로고    scopus 로고
    • Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning
    • Levin M, Thorlin T, Robinson KR, Nogi T, Mercola M, (2002) Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning. Cell 111: 77-89.
    • (2002) Cell , vol.111 , pp. 77-89
    • Levin, M.1    Thorlin, T.2    Robinson, K.R.3    Nogi, T.4    Mercola, M.5
  • 20
    • 0036007121 scopus 로고    scopus 로고
    • Ectodermal Syndecan-2 Mediates Left-Right Axis Formation in Migrating Mesoderm as a Cell-Nonautonomous Vg1 Cofactor
    • Kramer KL, Yost HJ, (2002) Ectodermal Syndecan-2 Mediates Left-Right Axis Formation in Migrating Mesoderm as a Cell-Nonautonomous Vg1 Cofactor. Developmental Cell 2: 115-124.
    • (2002) Developmental Cell , vol.2 , pp. 115-124
    • Kramer, K.L.1    Yost, H.J.2
  • 21
    • 28444473118 scopus 로고    scopus 로고
    • Do we know anything about how left-right asymmetry is first established in the vertebrate embryo?
    • Tabin C, (2005) Do we know anything about how left-right asymmetry is first established in the vertebrate embryo? J Mol Histol 36: 317-323.
    • (2005) J Mol Histol , vol.36 , pp. 317-323
    • Tabin, C.1
  • 22
    • 0037106188 scopus 로고    scopus 로고
    • Nodal activity in the node governs left-right asymmetry
    • Brennan J, Norris DP, Robertson EJ, (2002) Nodal activity in the node governs left-right asymmetry. Genes Dev 16: 2339-2344.
    • (2002) Genes Dev , vol.16 , pp. 2339-2344
    • Brennan, J.1    Norris, D.P.2    Robertson, E.J.3
  • 23
    • 0037377604 scopus 로고    scopus 로고
    • Left-right patterning of the mouse lateral plate requires nodal produced in the node
    • Saijoh Y, Oki S, Ohishi S, Hamada H, (2003) Left-right patterning of the mouse lateral plate requires nodal produced in the node. Dev Biol 256: 160-172.
    • (2003) Dev Biol , vol.256 , pp. 160-172
    • Saijoh, Y.1    Oki, S.2    Ohishi, S.3    Hamada, H.4
  • 24
    • 37249093137 scopus 로고    scopus 로고
    • Long-range action of Nodal requires interaction with GDF1
    • Tanaka C, Sakuma R, Nakamura T, Hamada H, Saijoh Y, (2007) Long-range action of Nodal requires interaction with GDF1. Genes Dev 21: 3272-3282.
    • (2007) Genes Dev , vol.21 , pp. 3272-3282
    • Tanaka, C.1    Sakuma, R.2    Nakamura, T.3    Hamada, H.4    Saijoh, Y.5
  • 25
    • 0032952544 scopus 로고    scopus 로고
    • The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping
    • Campione M, Steinbeisser H, Schweickert A, Deissler K, van Bebber F, et al. (1999) The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping. Development 126: 1225-1234.
    • (1999) Development , vol.126 , pp. 1225-1234
    • Campione, M.1    Steinbeisser, H.2    Schweickert, A.3    Deissler, K.4    van Bebber, F.5
  • 26
    • 0032493866 scopus 로고    scopus 로고
    • Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry
    • Yoshioka H, Meno C, Koshiba K, Sugihara M, Itoh H, et al. (1998) Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry. Cell 94: 299-305.
    • (1998) Cell , vol.94 , pp. 299-305
    • Yoshioka, H.1    Meno, C.2    Koshiba, K.3    Sugihara, M.4    Itoh, H.5
  • 27
    • 0033575873 scopus 로고    scopus 로고
    • Function of Rieger syndrome gene in left-right asymmetry and craniofacial development
    • Lu MF, Pressman C, Dyer R, Johnson RL, Martin JF, (1999) Function of Rieger syndrome gene in left-right asymmetry and craniofacial development. Nature 401: 276-278.
    • (1999) Nature , vol.401 , pp. 276-278
    • Lu, M.F.1    Pressman, C.2    Dyer, R.3    Johnson, R.L.4    Martin, J.F.5
  • 28
    • 33645110732 scopus 로고    scopus 로고
    • Left-right asymmetry in the vertebrate embryo: from early information to higher-level integration
    • Raya A, Belmonte JC, (2006) Left-right asymmetry in the vertebrate embryo: from early information to higher-level integration. Nat Rev Genet 7: 283-293.
    • (2006) Nat Rev Genet , vol.7 , pp. 283-293
    • Raya, A.1    Belmonte, J.C.2
  • 29
    • 84856321241 scopus 로고    scopus 로고
    • Linking early determinants and cilia-driven leftward flow in left-right axis specification of Xenopus laevis: a theoretical approach
    • Schweickert A, Walentek P, Thumberger T, Danilchik M, (2012) Linking early determinants and cilia-driven leftward flow in left-right axis specification of Xenopus laevis: a theoretical approach. Differentiation 83: S67-77.
    • (2012) Differentiation , vol.83
    • Schweickert, A.1    Walentek, P.2    Thumberger, T.3    Danilchik, M.4
  • 30
    • 78649716684 scopus 로고    scopus 로고
    • Far from solved: a perspective on what we know about early mechanisms of left-right asymmetry
    • Vandenberg LN, Levin M, (2010) Far from solved: a perspective on what we know about early mechanisms of left-right asymmetry. Dev Dyn 239: 3131-3146.
    • (2010) Dev Dyn , vol.239 , pp. 3131-3146
    • Vandenberg, L.N.1    Levin, M.2
  • 31
    • 18744413944 scopus 로고    scopus 로고
    • Retinoic acid signalling links left-right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo
    • Kawakami Y, Raya A, Raya RM, Rodriguez-Esteban C, Belmonte JC, (2005) Retinoic acid signalling links left-right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo. Nature 435: 165-171.
    • (2005) Nature , vol.435 , pp. 165-171
    • Kawakami, Y.1    Raya, A.2    Raya, R.M.3    Rodriguez-Esteban, C.4    Belmonte, J.C.5
  • 32
    • 33645870420 scopus 로고    scopus 로고
    • Ion flow regulates left-right asymmetry in sea urchin development
    • Hibino T, Ishii Y, Levin M, Nishino A, (2006) Ion flow regulates left-right asymmetry in sea urchin development. Dev Genes Evol 216: 265-276.
    • (2006) Dev Genes Evol , vol.216 , pp. 265-276
    • Hibino, T.1    Ishii, Y.2    Levin, M.3    Nishino, A.4
  • 33
    • 0347192982 scopus 로고    scopus 로고
    • Notch activity acts as a sensor for extracellular calcium during vertebrate left-right determination
    • Raya A, Kawakami Y, Rodriguez-Esteban C, Ibanes M, Rasskin-Gutman D, et al. (2004) Notch activity acts as a sensor for extracellular calcium during vertebrate left-right determination. Nature 427: 121-128.
    • (2004) Nature , vol.427 , pp. 121-128
    • Raya, A.1    Kawakami, Y.2    Rodriguez-Esteban, C.3    Ibanes, M.4    Rasskin-Gutman, D.5
  • 34
    • 84861685205 scopus 로고    scopus 로고
    • ATP4a Is Required for Wnt-Dependent Foxj1 Expression and Leftward Flow in Xenopus Left-Right Development
    • Walentek P, Beyer T, Thumberger T, Schweickert A, Blum M, (2012) ATP4a Is Required for Wnt-Dependent Foxj1 Expression and Leftward Flow in Xenopus Left-Right Development. Cell Rep 1: 516-527.
    • (2012) Cell Rep , vol.1 , pp. 516-527
    • Walentek, P.1    Beyer, T.2    Thumberger, T.3    Schweickert, A.4    Blum, M.5
  • 35
    • 0037232490 scopus 로고    scopus 로고
    • Node and midline defects are associated with left-right development in Delta1 mutant embryos
    • Przemeck GK, Heinzmann U, Beckers J, Hrabe de Angelis M, (2003) Node and midline defects are associated with left-right development in Delta1 mutant embryos. Development 130: 3-13.
    • (2003) Development , vol.130 , pp. 3-13
    • Przemeck, G.K.1    Heinzmann, U.2    Beckers, J.3    Hrabe de Angelis, M.4
  • 36
    • 0037598796 scopus 로고    scopus 로고
    • Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos
    • Raya A, Kawakami Y, Rodriguez-Esteban C, Buscher D, Koth CM, et al. (2003) Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos. Genes Dev 17: 1213-1218.
    • (2003) Genes Dev , vol.17 , pp. 1213-1218
    • Raya, A.1    Kawakami, Y.2    Rodriguez-Esteban, C.3    Buscher, D.4    Koth, C.M.5
  • 37
    • 0038274073 scopus 로고    scopus 로고
    • Notch signaling regulates left-right asymmetry determination by inducing Nodal expression
    • Krebs LT, Iwai N, Nonaka S, Welsh IC, Lan Y, et al. (2003) Notch signaling regulates left-right asymmetry determination by inducing Nodal expression. Genes Dev 17: 1207-1212.
    • (2003) Genes Dev , vol.17 , pp. 1207-1212
    • Krebs, L.T.1    Iwai, N.2    Nonaka, S.3    Welsh, I.C.4    Lan, Y.5
  • 38
    • 0039038195 scopus 로고
    • Echinoids
    • In: Reverberi G, editor, Amsterdam: North-Holland Publ
    • Czihak G (1971) Echinoids. In: Reverberi G, editor. Experimental embryology of marine invertebrates. Amsterdam: North-Holland Publ.,. pp. 363-482.
    • (1971) Experimental embryology of marine invertebrates , pp. 363-482
    • Czihak, G.1
  • 40
    • 0030068244 scopus 로고    scopus 로고
    • A fate map of the vegetal plate of the sea urchin (Lytechinus variegatus) mesenchyme blastula
    • Ruffins SW, Ettensohn CA, (1996) A fate map of the vegetal plate of the sea urchin (Lytechinus variegatus) mesenchyme blastula. Development 122: 253-263.
    • (1996) Development , vol.122 , pp. 253-263
    • Ruffins, S.W.1    Ettensohn, C.A.2
  • 41
    • 0032934519 scopus 로고    scopus 로고
    • LvNotch signaling mediates secondary mesenchyme specification in the sea urchin embryo
    • Sherwood DR, McClay DR, (1999) LvNotch signaling mediates secondary mesenchyme specification in the sea urchin embryo. Development 126: 1703-1713.
    • (1999) Development , vol.126 , pp. 1703-1713
    • Sherwood, D.R.1    McClay, D.R.2
  • 42
    • 0036333533 scopus 로고    scopus 로고
    • LvDelta is a mesoderm-inducing signal in the sea urchin embryo and can endow blastomeres with organizer-like properties
    • Sweet HC, Gehring M, Ettensohn CA, (2002) LvDelta is a mesoderm-inducing signal in the sea urchin embryo and can endow blastomeres with organizer-like properties. Development 129: 1945-1955.
    • (2002) Development , vol.129 , pp. 1945-1955
    • Sweet, H.C.1    Gehring, M.2    Ettensohn, C.A.3
  • 43
    • 0022476610 scopus 로고
    • The fate of the small micromeres in sea urchin development
    • Pehrson JR, Cohen LH, (1986) The fate of the small micromeres in sea urchin development. Dev Biol 113: 522-526.
    • (1986) Dev Biol , vol.113 , pp. 522-526
    • Pehrson, J.R.1    Cohen, L.H.2
  • 44
    • 0028137884 scopus 로고
    • The establishment of bilateral asymmetry in sea urchin embryos
    • McCain ER, McClay D, (1994) The establishment of bilateral asymmetry in sea urchin embryos. Development 120: 395-404.
    • (1994) Development , vol.120 , pp. 395-404
    • McCain, E.R.1    McClay, D.2
  • 45
    • 0347616545 scopus 로고    scopus 로고
    • Inversion of left-right asymmetry in the formation of the adult rudiment in sea urchin larvae: removal of a part of embryos at the gastrula stage
    • Aihara M, Amemiya S, (2000) Inversion of left-right asymmetry in the formation of the adult rudiment in sea urchin larvae: removal of a part of embryos at the gastrula stage. Zygote 8 Suppl 1: S82-83.
    • (2000) Zygote , vol.8 , Issue.SUPPL. 1
    • Aihara, M.1    Amemiya, S.2
  • 46
    • 34248388064 scopus 로고    scopus 로고
    • Micromere-derived signal regulates larval left-right polarity during sea urchin development
    • Kitazawa C, Amemiya S, (2007) Micromere-derived signal regulates larval left-right polarity during sea urchin development. J Exp Zool Part A Ecol Genet Physiol 307: 249-262.
    • (2007) J Exp Zool Part A Ecol Genet Physiol , vol.307 , pp. 249-262
    • Kitazawa, C.1    Amemiya, S.2
  • 47
    • 73649148396 scopus 로고    scopus 로고
    • Dynamics of Delta/Notch signaling on endomesoderm segregation in the sea urchin embryo
    • Croce JC, McClay DR, (2010) Dynamics of Delta/Notch signaling on endomesoderm segregation in the sea urchin embryo. Development 137: 83-91.
    • (2010) Development , vol.137 , pp. 83-91
    • Croce, J.C.1    McClay, D.R.2
  • 48
    • 33751504336 scopus 로고    scopus 로고
    • Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo
    • Rottinger E, Croce J, Lhomond G, Besnardeau L, Gache C, et al. (2006) Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo. Development 133: 4341-4353.
    • (2006) Development , vol.133 , pp. 4341-4353
    • Rottinger, E.1    Croce, J.2    Lhomond, G.3    Besnardeau, L.4    Gache, C.5
  • 49
    • 33748467781 scopus 로고    scopus 로고
    • cis-regulatory processing of Notch signaling input to the sea urchin glial cells missing gene during mesoderm specification
    • Ransick A, Davidson EH, (2006) cis-regulatory processing of Notch signaling input to the sea urchin glial cells missing gene during mesoderm specification. Dev Biol 297: 587-602.
    • (2006) Dev Biol , vol.297 , pp. 587-602
    • Ransick, A.1    Davidson, E.H.2
  • 50
    • 73649110278 scopus 로고    scopus 로고
    • Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo
    • Duboc V, Lapraz F, Saudemont A, Bessodes N, Mekpoh F, et al. (2010) Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo. Development 137: 223-235.
    • (2010) Development , vol.137 , pp. 223-235
    • Duboc, V.1    Lapraz, F.2    Saudemont, A.3    Bessodes, N.4    Mekpoh, F.5
  • 51
    • 84857505161 scopus 로고    scopus 로고
    • A comprehensive analysis of Delta signaling in pre-gastrular sea urchin embryos
    • Materna SC, Davidson EH, (2012) A comprehensive analysis of Delta signaling in pre-gastrular sea urchin embryos. Dev Biol 364: 77-87.
    • (2012) Dev Biol , vol.364 , pp. 77-87
    • Materna, S.C.1    Davidson, E.H.2
  • 52
    • 0023489922 scopus 로고
    • Localization and expression of msp130, a primary mesenchyme lineage- specific cell surface protein in the sea urchin embryo
    • Anstrom JA, Chin JE, Leaf DS, Parks AL, Raff RA, (1987) Localization and expression of msp130, a primary mesenchyme lineage- specific cell surface protein in the sea urchin embryo. Development 101: 255-265.
    • (1987) Development , vol.101 , pp. 255-265
    • Anstrom, J.A.1    Chin, J.E.2    Leaf, D.S.3    Parks, A.L.4    Raff, R.A.5
  • 53
    • 33751514939 scopus 로고    scopus 로고
    • Repression of mesodermal fate by foxa, a key endoderm regulator of the sea urchin embryo
    • Oliveri P, Walton KD, Davidson EH, McClay DR, (2006) Repression of mesodermal fate by foxa, a key endoderm regulator of the sea urchin embryo. Development 133: 4173-4181.
    • (2006) Development , vol.133 , pp. 4173-4181
    • Oliveri, P.1    Walton, K.D.2    Davidson, E.H.3    McClay, D.R.4
  • 54
    • 84856683088 scopus 로고    scopus 로고
    • Sequential signaling crosstalk regulates endomesoderm segregation in sea urchin embryos
    • Sethi AJ, Wikramanayake RM, Angerer RC, Range RC, Angerer LM, (2012) Sequential signaling crosstalk regulates endomesoderm segregation in sea urchin embryos. Science 335: 590-593.
    • (2012) Science , vol.335 , pp. 590-593
    • Sethi, A.J.1    Wikramanayake, R.M.2    Angerer, R.C.3    Range, R.C.4    Angerer, L.M.5
  • 55
    • 77953474257 scopus 로고    scopus 로고
    • Information processing at the foxa node of the sea urchin endomesoderm specification network
    • de-Leon SB, Davidson EH, (2010) Information processing at the foxa node of the sea urchin endomesoderm specification network. Proc Natl Acad Sci U S A 107: 10103-10108.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10103-10108
    • de-Leon, S.B.1    Davidson, E.H.2
  • 56
    • 77951205560 scopus 로고    scopus 로고
    • The endoderm gene regulatory network in sea urchin embryos up to mid-blastula stage
    • Peter IS, Davidson EH, (2010) The endoderm gene regulatory network in sea urchin embryos up to mid-blastula stage. Dev Biol 340: 188-199.
    • (2010) Dev Biol , vol.340 , pp. 188-199
    • Peter, I.S.1    Davidson, E.H.2
  • 58
    • 1242265691 scopus 로고    scopus 로고
    • Regulation of notch signaling activity
    • Schweisguth F, (2004) Regulation of notch signaling activity. Curr Biol 14: R129-138.
    • (2004) Curr Biol , vol.14
    • Schweisguth, F.1
  • 60
    • 18744406718 scopus 로고    scopus 로고
    • FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination
    • Tanaka Y, Okada Y, Hirokawa N, (2005) FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination. Nature 435: 172-177.
    • (2005) Nature , vol.435 , pp. 172-177
    • Tanaka, Y.1    Okada, Y.2    Hirokawa, N.3
  • 61
    • 63949088362 scopus 로고    scopus 로고
    • FGF signalling during embryo development regulates cilia length in diverse epithelia
    • Neugebauer JM, Amack JD, Peterson AG, Bisgrove BW, Yost HJ, (2009) FGF signalling during embryo development regulates cilia length in diverse epithelia. Nature 458: 651-654.
    • (2009) Nature , vol.458 , pp. 651-654
    • Neugebauer, J.M.1    Amack, J.D.2    Peterson, A.G.3    Bisgrove, B.W.4    Yost, H.J.5
  • 62
    • 38949085860 scopus 로고    scopus 로고
    • FGF signals guide migration of mesenchymal cells, control skeletal morphogenesis [corrected] and regulate gastrulation during sea urchin development
    • Rottinger E, Saudemont A, Duboc V, Besnardeau L, McClay D, et al. (2008) FGF signals guide migration of mesenchymal cells, control skeletal morphogenesis [corrected] and regulate gastrulation during sea urchin development. Development 135: 353-365.
    • (2008) Development , vol.135 , pp. 353-365
    • Rottinger, E.1    Saudemont, A.2    Duboc, V.3    Besnardeau, L.4    McClay, D.5
  • 63
    • 78650699481 scopus 로고    scopus 로고
    • Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm
    • doi:10.1371/journal.pgen.1001259
    • Saudemont A, Haillot E, Mekpoh F, Bessodes N, Quirin M, et al. (2010) Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm. PLoS Genet 6: e1001259 doi:10.1371/journal.pgen.1001259.
    • (2010) PLoS Genet , vol.6
    • Saudemont, A.1    Haillot, E.2    Mekpoh, F.3    Bessodes, N.4    Quirin, M.5
  • 64
    • 33745909944 scopus 로고    scopus 로고
    • Specification of ectoderm restricts the size of the animal plate and patterns neurogenesis in sea urchin embryos
    • Yaguchi S, Yaguchi J, Burke RD, (2006) Specification of ectoderm restricts the size of the animal plate and patterns neurogenesis in sea urchin embryos. Development 133: 2337-2346.
    • (2006) Development , vol.133 , pp. 2337-2346
    • Yaguchi, S.1    Yaguchi, J.2    Burke, R.D.3
  • 65
    • 72949097669 scopus 로고    scopus 로고
    • Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-chordin signaling network
    • doi:10.1371/journal.pbio.1000248
    • Lapraz F, Besnardeau L, Lepage T, (2009) Patterning of the dorsal-ventral axis in echinoderms: insights into the evolution of the BMP-chordin signaling network. PLoS Biol 7: e1000248 doi:10.1371/journal.pbio.1000248.
    • (2009) PLoS Biol , vol.7
    • Lapraz, F.1    Besnardeau, L.2    Lepage, T.3
  • 66
    • 12144288504 scopus 로고    scopus 로고
    • Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo
    • Duboc V, Rottinger E, Besnardeau L, Lepage T, (2004) Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo. Dev Cell 6: 397-410.
    • (2004) Dev Cell , vol.6 , pp. 397-410
    • Duboc, V.1    Rottinger, E.2    Besnardeau, L.3    Lepage, T.4
  • 67
    • 0032428685 scopus 로고    scopus 로고
    • Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
    • Nonaka S, Tanaka Y, Okada Y, Takeda S, Harada A, et al. (1998) Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95: 829-837.
    • (1998) Cell , vol.95 , pp. 829-837
    • Nonaka, S.1    Tanaka, Y.2    Okada, Y.3    Takeda, S.4    Harada, A.5
  • 68
    • 19344367605 scopus 로고    scopus 로고
    • Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination
    • Okada Y, Takeda S, Tanaka Y, Belmonte JC, Hirokawa N, (2005) Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination. Cell 121: 633-644.
    • (2005) Cell , vol.121 , pp. 633-644
    • Okada, Y.1    Takeda, S.2    Tanaka, Y.3    Belmonte, J.C.4    Hirokawa, N.5
  • 69
    • 17244366458 scopus 로고    scopus 로고
    • Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut
    • Essner JJ, Amack JD, Nyholm MK, Harris EB, Yost HJ, (2005) Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut. Development 132: 1247-1260.
    • (2005) Development , vol.132 , pp. 1247-1260
    • Essner, J.J.1    Amack, J.D.2    Nyholm, M.K.3    Harris, E.B.4    Yost, H.J.5
  • 70
    • 18844393668 scopus 로고    scopus 로고
    • Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis
    • Kramer-Zucker AG, Olale F, Haycraft CJ, Yoder BK, Schier AF, et al. (2005) Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development 132: 1907-1921.
    • (2005) Development , vol.132 , pp. 1907-1921
    • Kramer-Zucker, A.G.1    Olale, F.2    Haycraft, C.J.3    Yoder, B.K.4    Schier, A.F.5
  • 71
    • 33845872286 scopus 로고    scopus 로고
    • Cilia-driven leftward flow determines laterality in Xenopus
    • Schweickert A, Weber T, Beyer T, Vick P, Bogusch S, et al. (2007) Cilia-driven leftward flow determines laterality in Xenopus. Curr Biol 17: 60-66.
    • (2007) Curr Biol , vol.17 , pp. 60-66
    • Schweickert, A.1    Weber, T.2    Beyer, T.3    Vick, P.4    Bogusch, S.5
  • 72
    • 0029854744 scopus 로고    scopus 로고
    • Initiation of vertebrate left-right axis formation by maternal Vg1
    • Hyatt BA, Lohr JL, Yost HJ, (1996) Initiation of vertebrate left-right axis formation by maternal Vg1. Nature 384: 62-65.
    • (1996) Nature , vol.384 , pp. 62-65
    • Hyatt, B.A.1    Lohr, J.L.2    Yost, H.J.3
  • 73
    • 19344369929 scopus 로고    scopus 로고
    • Lefty Blocks a Subset of TGFbeta Signals by Antagonizing EGF-CFC Coreceptors
    • doi:10.1371/journal.pbio.0020030
    • Cheng SK, Olale F, Brivanlou AH, Schier AF, (2004) Lefty Blocks a Subset of TGFbeta Signals by Antagonizing EGF-CFC Coreceptors. PLoS Biol 2: e30 doi:10.1371/journal.pbio.0020030.
    • (2004) PLoS Biol , vol.2
    • Cheng, S.K.1    Olale, F.2    Brivanlou, A.H.3    Schier, A.F.4
  • 74
    • 0034050737 scopus 로고    scopus 로고
    • Regulation of left-right patterning in mice by growth/differentiation factor-1
    • Rankin CT, Bunton T, Lawler AM, Lee SJ, (2000) Regulation of left-right patterning in mice by growth/differentiation factor-1. Nat Genet 24: 262-265.
    • (2000) Nat Genet , vol.24 , pp. 262-265
    • Rankin, C.T.1    Bunton, T.2    Lawler, A.M.3    Lee, S.J.4
  • 75
    • 78049341348 scopus 로고    scopus 로고
    • Notch signalling regulates left-right asymmetry through ciliary length control
    • Lopes SS, Lourenco R, Pacheco L, Moreno N, Kreiling J, et al. (2010) Notch signalling regulates left-right asymmetry through ciliary length control. Development 137: 3625-3632.
    • (2010) Development , vol.137 , pp. 3625-3632
    • Lopes, S.S.1    Lourenco, R.2    Pacheco, L.3    Moreno, N.4    Kreiling, J.5
  • 76
    • 34548073070 scopus 로고    scopus 로고
    • Nodal activity around Kupffer's vesicle depends on the T-box transcription factors Notail and Spadetail and on Notch signaling
    • Gourronc F, Ahmad N, Nedza N, Eggleston T, Rebagliati M, (2007) Nodal activity around Kupffer's vesicle depends on the T-box transcription factors Notail and Spadetail and on Notch signaling. Dev Dyn 236: 2131-2146.
    • (2007) Dev Dyn , vol.236 , pp. 2131-2146
    • Gourronc, F.1    Ahmad, N.2    Nedza, N.3    Eggleston, T.4    Rebagliati, M.5
  • 77
    • 0027104493 scopus 로고
    • Cell interactions and mesodermal cell fates in the sea urchin embryo
    • Ettensohn CA, (1992) Cell interactions and mesodermal cell fates in the sea urchin embryo. Dev Suppl pp. 43-51.
    • (1992) Dev Suppl , pp. 43-51
    • Ettensohn, C.A.1
  • 78
    • 0033377612 scopus 로고    scopus 로고
    • The role of micromere signaling in Notch activation and mesoderm specification during sea urchin embryogenesis
    • Sweet HC, Hodor PG, Ettensohn CA, (1999) The role of micromere signaling in Notch activation and mesoderm specification during sea urchin embryogenesis. Development 126: 5255-5265.
    • (1999) Development , vol.126 , pp. 5255-5265
    • Sweet, H.C.1    Hodor, P.G.2    Ettensohn, C.A.3
  • 79
    • 0034528229 scopus 로고    scopus 로고
    • A micromere induction signal is activated by beta-catenin and acts through notch to initiate specification of secondary mesenchyme cells in the sea urchin embryo
    • McClay DR, Peterson RE, Range RC, Winter-Vann AM, Ferkowicz MJ, (2000) A micromere induction signal is activated by beta-catenin and acts through notch to initiate specification of secondary mesenchyme cells in the sea urchin embryo. Development 127: 5113-5122.
    • (2000) Development , vol.127 , pp. 5113-5122
    • McClay, D.R.1    Peterson, R.E.2    Range, R.C.3    Winter-Vann, A.M.4    Ferkowicz, M.J.5
  • 80
    • 33244498052 scopus 로고    scopus 로고
    • Frizzled5/8 is required in secondary mesenchyme cells to initiate archenteron invagination during sea urchin development
    • Croce J, Duloquin L, Lhomond G, McClay DR, Gache C, (2006) Frizzled5/8 is required in secondary mesenchyme cells to initiate archenteron invagination during sea urchin development. Development 133: 547-557.
    • (2006) Development , vol.133 , pp. 547-557
    • Croce, J.1    Duloquin, L.2    Lhomond, G.3    McClay, D.R.4    Gache, C.5
  • 81
    • 1642378927 scopus 로고    scopus 로고
    • Pigment cells trigger the onset of gastrulation in tropical sea urchin Echinometra mathaei
    • Takata H, Kominami T, (2004) Pigment cells trigger the onset of gastrulation in tropical sea urchin Echinometra mathaei. Dev Growth Differ 46: 23-35.
    • (2004) Dev Growth Differ , vol.46 , pp. 23-35
    • Takata, H.1    Kominami, T.2
  • 82
    • 84855433919 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling directly regulates Foxj1 expression and ciliogenesis in zebrafish Kupffer's vesicle
    • Caron A, Xu X, Lin X, (2012) Wnt/beta-catenin signaling directly regulates Foxj1 expression and ciliogenesis in zebrafish Kupffer's vesicle. Development 139: 514-524.
    • (2012) Development , vol.139 , pp. 514-524
    • Caron, A.1    Xu, X.2    Lin, X.3
  • 83
    • 0031595573 scopus 로고    scopus 로고
    • GSK3beta/shaggy mediates patterning along the animal-vegetal axis of the sea urchin embryo
    • Emily-Fenouil F, Ghiglione C, Lhomond G, Lepage T, Gache C, (1998) GSK3beta/shaggy mediates patterning along the animal-vegetal axis of the sea urchin embryo. Development 125: 2489-2498.
    • (1998) Development , vol.125 , pp. 2489-2498
    • Emily-Fenouil, F.1    Ghiglione, C.2    Lhomond, G.3    Lepage, T.4    Gache, C.5
  • 84
    • 0032914194 scopus 로고    scopus 로고
    • Nuclear beta-catenin is required to specify vegetal cell fates in the sea urchin embryo
    • Logan CY, Miller JR, Ferkowicz MJ, McClay DR, (1999) Nuclear beta-catenin is required to specify vegetal cell fates in the sea urchin embryo. Development 126: 345-357.
    • (1999) Development , vol.126 , pp. 345-357
    • Logan, C.Y.1    Miller, J.R.2    Ferkowicz, M.J.3    McClay, D.R.4
  • 85
    • 77952184721 scopus 로고    scopus 로고
    • The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor
    • Vaccari T, Duchi S, Cortese K, Tacchetti C, Bilder D, (2010) The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor. Development 137: 1825-1832.
    • (2010) Development , vol.137 , pp. 1825-1832
    • Vaccari, T.1    Duchi, S.2    Cortese, K.3    Tacchetti, C.4    Bilder, D.5
  • 86
    • 69949137273 scopus 로고    scopus 로고
    • The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila
    • Yan Y, Denef N, Schupbach T, (2009) The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila. Dev Cell 17: 387-402.
    • (2009) Dev Cell , vol.17 , pp. 387-402
    • Yan, Y.1    Denef, N.2    Schupbach, T.3
  • 87
    • 0027538120 scopus 로고
    • An ion-transporting ATPase encodes multiple apical localization signals
    • Gottardi CJ, Caplan MJ, (1993) An ion-transporting ATPase encodes multiple apical localization signals. J Cell Biol 121: 283-293.
    • (1993) J Cell Biol , vol.121 , pp. 283-293
    • Gottardi, C.J.1    Caplan, M.J.2
  • 89
    • 7544219964 scopus 로고    scopus 로고
    • BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo
    • Kishigami S, Yoshikawa S, Castranio T, Okazaki K, Furuta Y, et al. (2004) BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo. Dev Biol 276: 185-193.
    • (2004) Dev Biol , vol.276 , pp. 185-193
    • Kishigami, S.1    Yoshikawa, S.2    Castranio, T.3    Okazaki, K.4    Furuta, Y.5
  • 90
    • 34247560264 scopus 로고    scopus 로고
    • Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points
    • Chocron S, Verhoeven MC, Rentzsch F, Hammerschmidt M, Bakkers J, (2007) Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Dev Biol 305: 577-588.
    • (2007) Dev Biol , vol.305 , pp. 577-588
    • Chocron, S.1    Verhoeven, M.C.2    Rentzsch, F.3    Hammerschmidt, M.4    Bakkers, J.5
  • 91
    • 55749099692 scopus 로고    scopus 로고
    • BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4
    • Furtado MB, Solloway MJ, Jones VJ, Costa MW, Biben C, et al. (2008) BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4. Genes Dev 22: 3037-3049.
    • (2008) Genes Dev , vol.22 , pp. 3037-3049
    • Furtado, M.B.1    Solloway, M.J.2    Jones, V.J.3    Costa, M.W.4    Biben, C.5
  • 92
    • 80053456655 scopus 로고    scopus 로고
    • Bmp and Nodal Independently Regulate lefty1 Expression to Maintain Unilateral Nodal Activity during Left-Right Axis Specification in Zebrafish
    • doi:10.1371/journal.pgen.1002289
    • Smith KA, Noel E, Thurlings I, Rehmann H, Chocron S, et al. (2011) Bmp and Nodal Independently Regulate lefty1 Expression to Maintain Unilateral Nodal Activity during Left-Right Axis Specification in Zebrafish. PLoS Genet 7: e1002289 doi:10.1371/journal.pgen.1002289.
    • (2011) PLoS Genet , vol.7
    • Smith, K.A.1    Noel, E.2    Thurlings, I.3    Rehmann, H.4    Chocron, S.5
  • 93
    • 0343605257 scopus 로고    scopus 로고
    • Left-right asymmetry in BMP4 signalling pathway during chick gastrulation
    • Monsoro-Burq A, Le Douarin N, (2000) Left-right asymmetry in BMP4 signalling pathway during chick gastrulation. Mech Dev 97: 105-108.
    • (2000) Mech Dev , vol.97 , pp. 105-108
    • Monsoro-Burq, A.1    Le Douarin, N.2
  • 94
    • 0036638638 scopus 로고    scopus 로고
    • BMP signaling positively regulates Nodal expression during left right specification in the chick embryo
    • Piedra ME, Ros MA, (2002) BMP signaling positively regulates Nodal expression during left right specification in the chick embryo. Development 129: 3431-3440.
    • (2002) Development , vol.129 , pp. 3431-3440
    • Piedra, M.E.1    Ros, M.A.2
  • 95
    • 0036638625 scopus 로고    scopus 로고
    • BMP2 is a positive regulator of Nodal signaling during left-right axis formation in the chicken embryo
    • Schlange T, Arnold HH, Brand T, (2002) BMP2 is a positive regulator of Nodal signaling during left-right axis formation in the chicken embryo. Development 129: 3421-3429.
    • (2002) Development , vol.129 , pp. 3421-3429
    • Schlange, T.1    Arnold, H.H.2    Brand, T.3
  • 96
    • 70450284389 scopus 로고    scopus 로고
    • An Hh-dependent pathway in lateral plate mesoderm enables the generation of left/right asymmetry
    • Tsiairis CD, McMahon AP, (2009) An Hh-dependent pathway in lateral plate mesoderm enables the generation of left/right asymmetry. Curr Biol 19: 1912-1917.
    • (2009) Curr Biol , vol.19 , pp. 1912-1917
    • Tsiairis, C.D.1    McMahon, A.P.2
  • 97
    • 0036801060 scopus 로고    scopus 로고
    • Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse
    • Fujiwara T, Dehart DB, Sulik KK, Hogan BL, (2002) Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse. Development 129: 4685-4696.
    • (2002) Development , vol.129 , pp. 4685-4696
    • Fujiwara, T.1    Dehart, D.B.2    Sulik, K.K.3    Hogan, B.L.4
  • 98
    • 84858980401 scopus 로고    scopus 로고
    • Role of the gut endoderm in relaying left-right patterning in mice
    • doi:10.1371/journal.pbio.1001276
    • Viotti M, Niu L, Shi SH, Hadjantonakis AK, (2012) Role of the gut endoderm in relaying left-right patterning in mice. PLoS Biol 10: e1001276 doi:10.1371/journal.pbio.1001276.
    • (2012) PLoS Biol , vol.10
    • Viotti, M.1    Niu, L.2    Shi, S.H.3    Hadjantonakis, A.K.4
  • 100
    • 0029932564 scopus 로고    scopus 로고
    • Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos
    • Meno C, Saijoh Y, Fujii H, Ikeda M, Yokoyama T, et al. (1996) Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. Nature 381: 151-155.
    • (1996) Nature , vol.381 , pp. 151-155
    • Meno, C.1    Saijoh, Y.2    Fujii, H.3    Ikeda, M.4    Yokoyama, T.5
  • 101
    • 0032493876 scopus 로고    scopus 로고
    • lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal
    • Meno C, Shimono A, Saijoh Y, Yashiro K, Mochida K, et al. (1998) lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell 94: 287-297.
    • (1998) Cell , vol.94 , pp. 287-297
    • Meno, C.1    Shimono, A.2    Saijoh, Y.3    Yashiro, K.4    Mochida, K.5
  • 102
    • 33749042595 scopus 로고    scopus 로고
    • Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system
    • Nakamura T, Mine N, Nakaguchi E, Mochizuki A, Yamamoto M, et al. (2006) Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system. Dev Cell 11: 495-504.
    • (2006) Dev Cell , vol.11 , pp. 495-504
    • Nakamura, T.1    Mine, N.2    Nakaguchi, E.3    Mochizuki, A.4    Yamamoto, M.5
  • 103
    • 48949115139 scopus 로고    scopus 로고
    • Lefty acts as an essential modulator of Nodal activity during sea urchin oral-aboral axis formation
    • Duboc V, Lapraz F, Besnardeau L, Lepage T, (2008) Lefty acts as an essential modulator of Nodal activity during sea urchin oral-aboral axis formation. Dev Biol 320: 49-59.
    • (2008) Dev Biol , vol.320 , pp. 49-59
    • Duboc, V.1    Lapraz, F.2    Besnardeau, L.3    Lepage, T.4
  • 104
  • 105
    • 79956342935 scopus 로고    scopus 로고
    • Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells
    • doi:10.1371/journal.pone.0020143
    • Udelnow A, Kreyes A, Ellinger S, Landfester K, Walther P, et al. (2011) Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells. PLoS ONE 6: e20143 doi:10.1371/journal.pone.0020143.
    • (2011) PLoS ONE , vol.6
    • Udelnow, A.1    Kreyes, A.2    Ellinger, S.3    Landfester, K.4    Walther, P.5
  • 106
    • 84872012278 scopus 로고    scopus 로고
    • Anti-carcinogenic properties of omeprazole against human colon cancer formation in rats
    • Patlolla JM, Zhang Y, Li Q, Steele VE, Rao CV, (2011) Anti-carcinogenic properties of omeprazole against human colon cancer formation in rats. Int J Oncol.
    • (2011) Int J Oncol
    • Patlolla, J.M.1    Zhang, Y.2    Li, Q.3    Steele, V.E.4    Rao, C.V.5
  • 107
    • 0024598291 scopus 로고
    • Purification and characterization of the sea urchin embryo hatching enzyme
    • Lepage T, Gache C, (1989) Purification and characterization of the sea urchin embryo hatching enzyme. J Biol Chem 264: 4787-4793.
    • (1989) J Biol Chem , vol.264 , pp. 4787-4793
    • Lepage, T.1    Gache, C.2
  • 108
    • 33845903862 scopus 로고    scopus 로고
    • A conserved role for the nodal signaling pathway in the establishment of dorso-ventral and left-right axes in deuterostomes
    • Duboc V, Lepage T, (2006) A conserved role for the nodal signaling pathway in the establishment of dorso-ventral and left-right axes in deuterostomes. J Exp Zoolog B Mol Dev Evol.
    • (2006) J Exp Zoolog B Mol Dev Evol
    • Duboc, V.1    Lepage, T.2
  • 109
    • 36148930606 scopus 로고    scopus 로고
    • Cis-regulatory analysis of nodal and maternal control of dorsal-ventral axis formation by Univin, a TGF-{beta} related to Vg1
    • Range R, Lapraz F, Quirin M, Marro S, Besnardeau L, et al. (2007) Cis-regulatory analysis of nodal and maternal control of dorsal-ventral axis formation by Univin, a TGF-{beta} related to Vg1. Development 134: 3649-3664.
    • (2007) Development , vol.134 , pp. 3649-3664
    • Range, R.1    Lapraz, F.2    Quirin, M.3    Marro, S.4    Besnardeau, L.5
  • 110
    • 64549161094 scopus 로고    scopus 로고
    • Visualization, documentation, analysis, and communication of large-scale gene regulatory networks
    • Longabaugh WJ, Davidson EH, Bolouri H, (2009) Visualization, documentation, analysis, and communication of large-scale gene regulatory networks. Biochim Biophys Acta 1789: 363-374.
    • (2009) Biochim Biophys Acta , vol.1789 , pp. 363-374
    • Longabaugh, W.J.1    Davidson, E.H.2    Bolouri, H.3
  • 111
    • 16644403466 scopus 로고    scopus 로고
    • Using reporter genes to study cis-regulatory elements
    • Arnone MI, Dmochowski IJ, Gache C, (2004) Using reporter genes to study cis-regulatory elements. Methods Cell Biol 74: 621-652.
    • (2004) Methods Cell Biol , vol.74 , pp. 621-652
    • Arnone, M.I.1    Dmochowski, I.J.2    Gache, C.3
  • 112
    • 0026285616 scopus 로고
    • In situ hybridization: an improved whole mount method for Xenopus embryos
    • In: Kay BK, Peng HJ, editors, San Diego, Calif.: Academic Press Inc
    • Harland RM (1991) In situ hybridization: an improved whole mount method for Xenopus embryos. In: Kay BK, Peng HJ, editors. Methods in Cell Biology. San Diego, Calif.: Academic Press Inc. pp. 685-695.
    • (1991) Methods in Cell Biology , pp. 685-695
    • Harland, R.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.