Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor

Developmental Cell

Volumn 2, Issue 1, 2002, Pages 115-124

  Kramer, Kenneth L ^a   Yost, H Joseph ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR 1; ACTIVIN RECEPTOR LIKE KINASE 4; ACTIVIN RECEPTOR-LIKE KINASE 4; ENTEROPEPTIDASE; FIBRILLIN; FIBROGLYCAN; FIBRONECTIN; GLYCOPROTEIN; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN COFACTOR; MEMBRANE PROTEIN; PROTEIN SUBUNIT; PROTEOGLYCAN; PROTEOHEPARAN SULFATE; SYNDECAN; TRANSFORMING GROWTH FACTOR BETA; VG1 PROTEIN; PROTEIN; SDC2 PROTEIN, XENOPUS; SDC2 PROTEIN, ZEBRAFISH; SYNDECAN 2; VG1 PROTEIN, XENOPUS; XENOPUS PROTEIN; ZEBRAFISH PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL MIGRATION; CELL MOTION; CONTROLLED STUDY; CYTOLOGY; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; EMBRYOLOGY; GASTROINTESTINAL TRACT; GASTRULA; GASTRULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETICS; HEART; IN VIVO STUDY; INTESTINE; MESODERM; METABOLISM; MOLECULAR GENETICS; NONHUMAN; PHYSIOLOGY; PRIMORDIAL GERM CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SITUS INVERSUS; VISCERA; XENOPUS; DIGESTIVE SYSTEM; PRENATAL DEVELOPMENT;

ANIMALIA;

ACTIVIN RECEPTORS, TYPE I; AMINO ACID SEQUENCE; ANIMALS; CELL MOVEMENT; DIGESTIVE SYSTEM; ECTODERM; GASTRULA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; HEART; HEPARITIN SULFATE; MEMBRANE GLYCOPROTEINS; MESODERM; MOLECULAR SEQUENCE DATA; PROTEINS; PROTEOGLYCANS; SIGNAL TRANSDUCTION; SITUS INVERSUS; SYNDECAN-2; TRANSFORMING GROWTH FACTOR BETA; XENOPUS; XENOPUS PROTEINS; ZEBRAFISH PROTEINS;

EID: 0036007121     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(01)00107-1     Document Type: Article

References (41)

1. Functions of cell surface heparan sulfate proteoglycans
2. The development of handedness in left/right asymmetry
3. Conserved and divergent mechanisms in left-right axis formation
4. Syndecans: Multifunctional cell-surface coreceptors
5. Secretion and mesoderm-inducing activity of the TGF-beta-related domain of Xenopus Vg1
6. Developmental expression of the protein product of Vg1, a localized maternal mRNA in the frog Xenopus laevis
7. Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase
8. The TGF-beta family member derriere is involved in regulation of the establishment of left-right asymmetry
9. Beta-catenin signaling activity dissected in the early Xenopus embryo: A novel antisense approach
10. Inhibition of activin receptor signaling promotes neuralization in Xenopus
11. Dominant-negative. Smad2 mutants inhibit activin/Vg1 signaling and disrupt axis formation in Xenopus
12. A short polypeptide marker sequence useful for recombinant protein identification and purification
13. Initiation of vertabrate left-right axis formation by maternal Vg1
14. The left-right coordinator: The role of Vg1 in organizing left-right axis formation
15. Daily, a Drosophila glypican, controls cellular responses to the TGF-beta-related morphogen Dpp
16. Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation
17. Induction of dorsal mesoderm by soluble, mature Vg1 protein
18. Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue- and development-specific patterns
19. The left side gets all the best genes
20. Control of extra-cellular matrix assembly by syndecan-2 proteoglycan
21. Betaglycan binds inhibin and can mediate functional antagonism of activin signaling
22. Role of heparan sulfate proteoglycans in cell-cell signaling in drosophila
23. Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development
24. Asymmetry revisited
25. Cardiac looping and the vertebrate left-right axis: Antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent BMP pathway
26. Regulation of left-right patterning in mice by growth/differentiation factor-1
27. Molecular interactions of syndecans during development
28. The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development
29. Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3
30. Localized synthesis of the Vg1 protein during early Xenopus development
31. Embryonic expression patterns of Xenopus syndecans
32. Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures
33. Processed Vg1 protein is an axial mesoderm inducer in Xenopus
34. DNA sequences mediating the transcriptional response of the Mix.2 homeobox gene to mesoderm induction
35. Mesendoderm induction and reversal of left-right pattern by mouse gdf1, a Vg1-related gene
36. Formation and activation by phosphorylation of activin receptor complexes
37. Nodal signals to Smads through Cripto-Dependent and Cripto-Independent Mechanisms
38. Regulation of vertebrate left-right asymmetries by extracellular matrix
39. Diverse initiation in a conserved left-right pathway?
40. Repetitive Ser-Gly sequences enhance heparan sulfate assembly in proteoglycans
41. The syndecans, tuners of transmembrane signaling